Understanding the sensitivity of tidal flats to environmental changes is challenging.Currently,most studies rely on process-based models to systematically explain the morphodynamic evolution of tidal flats.In this stu...Understanding the sensitivity of tidal flats to environmental changes is challenging.Currently,most studies rely on process-based models to systematically explain the morphodynamic evolution of tidal flats.In this study,we proposed an alternative empirical approach to explore tidal flat dynamics using statistical indices based on long-term time series of daily surface elevation development.Surface elevation dynamic(SED)indices focus on the magnitude and period of surface elevation changes,while morphodynamic signature(MDS)indices relate sediment dynamics to environmental drivers.The statistical analyses were applied to an intervention site in the Netherlands to determine the effect of recently constructed groynes on the tidal flat.Using these analyses,we were able to(1)detect a reduction in the daily SED and(2)determine that the changes in the daily SED were predominantly caused by the reduction in wave impact between the groynes rather than the reduction in tidal currents.Overall,the presented results showed that the combination of novel statistical indices provides new insights into the trajectories of tidal flats,ecosystem functioning,and sensitivity to physical drivers(wind and tides).Finally,we suggested how the SED and MDS indices may help to explore the future trajectories and climate resilience of intertidal habitats.展开更多
Confluences play a major role in the dynamics of networks of natural and man-made open channels, and field measurements on river confluences reveal that discordance in bed elevation is common.Studies of schematized co...Confluences play a major role in the dynamics of networks of natural and man-made open channels, and field measurements on river confluences reveal that discordance in bed elevation is common.Studies of schematized confluences with a step at the interface between the tributary and the main channel bed reveal that bed elevation discordance is an important additional control for the confluence hydrodynamics.This study aimed to improve understanding of the influence of bed elevation discordance on the flow patterns and head losses in a right-angled confluence of an open channel with rectangular cross-sections.A large eddy simulation (LES)-based numerical model was set up and validated with experiments by others.Four configurations with different bed discordance ratios were investigated.The results confirm that, with increasing bed elevation discordance, the tributary streamlines at the confluence interface deviate less from the geometrical confluence angle, the extent of the recirculation zone (RZ) gets smaller, the ratio of the water depth upstream to that downstream of the confluence decreases, and the water level depression reduces.The bed elevation discordance also leads to the development of a large-scale structure in the lee of the step.Despite the appearance of the large-scale structure, the reduced extent of the RZ and associated changes in flow deflection/contraction reduce total head losses experienced by the main channel with an increase of the bed discordance ratio.It turns out that bed elevation discordance converts the lateral momentum from the tributary to streamwise momentum in the main channel more efficiently.展开更多
In China′s Loess Plateau area, gully head is the most active zone of a drainage system in gully areas. The differentiation of loess gully head follows geospatial patterns and reflects the process of the loess landfor...In China′s Loess Plateau area, gully head is the most active zone of a drainage system in gully areas. The differentiation of loess gully head follows geospatial patterns and reflects the process of the loess landform development and evolution of its drainage system to some extent. In this study, the geomorphic meaning, basic characteristics, morphological structure and the basic types of loess gully heads were systematically analysed. Then, the loess gully head′s conceptual model was established, and an extraction method based on Digital Elevation Model(DEM) for loess gully head features and elements was proposed. Through analysing the achieved statistics of loess gully head features, loess gully heads have apparently similar and different characteristics depending on the different loess landforms where they are found. The loess head characteristics reflect their growth period and evolution tendency to a certain degree, and they indirectly represent evolutionary mechanisms. In addition, the loess gully developmental stages and the evolutionary processes can be deduced by using loess gully head characteristics. This study is of great significance for development and improvement of the theoretical system for describing loess gully landforms.展开更多
AIM: To analyze changes of the optic nerve head(ONH) and peripapillary region during intraocular pressure(IOP) elevation in patients using spectral domain optical coherence tomography(SD-OCT).METHODS: Both an optic di...AIM: To analyze changes of the optic nerve head(ONH) and peripapillary region during intraocular pressure(IOP) elevation in patients using spectral domain optical coherence tomography(SD-OCT).METHODS: Both an optic disc 200×200 cube scan and a high-definition 5-line raster scan were obtained from open angle glaucoma patients presented with monocular elevation of IOP(≥30 mm Hg) using SD-OCT. Additional baseline characteristics included age, gender, diagnosis,best-corrected visual acuity, refractive error, findings of slit lamp biomicroscopy, findings of dilated stereoscopic examination of the ONH and fundus, IOP, pachymetry findings, and the results of visual field.RESULTS: The 24 patients were selected and divided into two groups: group 1 patients had no history of IOP elevation or glaucoma(n =14), and group 2 patients did have history of IOP elevation or glaucoma(n =10). In each patient, the study eye with elevated IOP was classified into group H(high), and the fellow eye was classified into group L(low). The mean deviation(MD)differed significantly between groups H and L when all eyes were considered(P =0.047) and in group 2(P =0.042), not in group 1(P =0.893). Retinal nerve fiber layer(RNFL) average thickness(P =0.050), rim area(P =0.015),vertical cup/disc ratio(P =0.011), cup volume(P =0.028),inferior quadrant RNFL thickness(P =0.017), and clockhour(1, 5, and 6) RNFL thicknesses(P =0.050, 0.012, and0.018, respectively), cup depth(P =0.008), central prelaminar layer thickness(P =0.023), mid-inferior prelaminar layer thickness(P =0.023), and nasal retinal slope(P =0.034)were significantly different between the eyes with groups H and L.CONCLUSION:RNFLaveragethickness,rim area,vertical cup/disc ratio, cup volume, inferior quadrant RNFL thickness, and clock-hour(1, 5, and 6) RNFL thicknesses significantly changed during acute IOP elevation.展开更多
The impact of temperature and particle size on minimumfluidizing velocity was studied and analyzed in a small pilot scale of bubbling fluidized bed reactor.This study was devoted to providing some data about fluidizat...The impact of temperature and particle size on minimumfluidizing velocity was studied and analyzed in a small pilot scale of bubbling fluidized bed reactor.This study was devoted to providing some data about fluidization to the literature under high temperature conditions.The experiments were carried out to evaluate the minimum fluidizing velocity over a vast range of temperature levels from 20℃ to 850℃ using silica sand with a particle size of 300-425μm,425-500μm,500-600μm,and 600-710μm.Furthermore,the variation in the minimumfluidized voidage was determined experimentally at the same conditions.The experimental data revealed that the Umf directly varied with particle size and inversely with temperature,whileεmf increases slightly with temperature based on the measurements of height at incipient fluidization.However,for all particle sizes used in this test,temperatures above 700℃ has a marginal effect on Umf.The results were compared with many empirical equations,and it was found that the experimental result is still in an acceptable range of empirical equations used.In which,our findings are not well predicted by the widely accepted correlations reported in the literature.Therefore,a new predicted equation has been developed that also accounts for the affecting of mean particle size in addition to other parameters.A good mean relative deviation of 5.473% between the experimental data and the predicted values was estimated from the correlation of the effective dimensionless group.Furthermore,the experimental work revealed that the minimum fluidizing velocity was not affected by the height of the bed even at high temperature.展开更多
This paper presents a new method for simulating the evolution of a gully head in a loess catchment with cellular automata(CA) based on the Fisher discriminant. The experimental site is an indoor loess catchment that w...This paper presents a new method for simulating the evolution of a gully head in a loess catchment with cellular automata(CA) based on the Fisher discriminant. The experimental site is an indoor loess catchment that was constructed in a fixed-intensity rainfall erosion test facility. Nine high-resolution digital elevation model(DEM) data sets were gathered by close range photogrammetry during different phases of the experiment. To simulate the evolution of the catchment gully head, we assumed the following. First, the 5th and 6th DEM data sets were used as a data source for acquiring the location of the catchment gully head and for obtaining spatial variables with GIS spatial analysis tools. Second, the Fisher discriminant was used to calculate the weight of the spatial variables to determine the transition probabilities. Third, CA model was structured to simulate the evolution of the gully head by iterative looping. The status of the cell in the CA models was dynamically updated at the end of each loop to obtain realistic results. Finally, the nearest neighbor, G-function, K-function, Moran′s I and fractal indexes were used to evaluate the model results. Overall, the CA model can be used to simulate the evolution of a loess gully head. The experiment demonstrated the advantages of the CA model which can simulate the dynamic evolution of gully head evolution in a catchment.展开更多
Objective: To study the changes in cardiopulmonary function induced by mid/long-term simulated microgravity with 6^° head down bed rest (HDBR), and the effects of Taikong Yangxin Prescription (太空养心方, TYP...Objective: To study the changes in cardiopulmonary function induced by mid/long-term simulated microgravity with 6^° head down bed rest (HDBR), and the effects of Taikong Yangxin Prescription (太空养心方, TYP) as a countermeasure. Methods: Fourteen healthy male volunteers were randomly divided into a control group and a Chinese medicine (CM) group (7 in each group) by a random digital table based on their body weight. Both groups underwent6^° HDBR for 60 days. Subjects in the CM group received daily TYP pills and subjects in the control group received daily placebo pills. Cardiac systolic and pumping functions were measured by echocardiography before HDBR; on days 20, 42, and 57 of HDBR; and on day 3 of recovery after HDBR (R+3). Cardiopulmonary functional reserve and exercise capacity were evaluated before HDBR, on day 29, and on day R+3 by exercise testing. Results: The heart rate (HR) increased gradually during HDBR. The HR was significantly higher on day 57 than before HDBR in the control group (P〈0.05), but did not increase significantly in the CM group. The stroke volume/stroke volume index, ejection fraction, and left ventricular fractional shortening tended to decrease over time in the control group, but not in the CM group. These parameters were significantly higher in the CM group than in the control group on day 42 (P〈0.05 or P〈0.01). Exercise testing showed that maximum 02 consumption (VO2max), metabolic equivalents, relative 02 consumption (VO2), 02 pulse, and exercise duration were significantly lower on day 29 than before HDBR in the control group, but not in the CM group. Conclusions: Sixty days of 6^° HDBR induced a reduction in cardiac systolic and pumping functions, and reduced cardiopulmonary functional reserve and exercise capacity. Administration of TYP significantly improved cardiac systolic and pumping functions, and maintained cardiopulmonary functional reserve and exercise capacity.展开更多
Background Elevating the head of bed (HOB) 30°-45° has been widely supported as a means of ventilator associated pneumonia (VAP) prevention. However, it was poorly adhered in clinical practice. This obse...Background Elevating the head of bed (HOB) 30°-45° has been widely supported as a means of ventilator associated pneumonia (VAP) prevention. However, it was poorly adhered in clinical practice. This observational study aimed to investigate the factors impeding this simple practice at the bedside. Methods This prospective study was conducted in 33 Chinese academic hospital intensive care units (ICUs). HOB angle was measured four times daily at 5-7 hour intervals. The predefined HOB elevation goal was an angle ≥30°. Results The overall rate of achieving the HOB goal was 27.8% of the 8647 measurements in 314 patients during 2842 ventilation days. The HOB goal of ≥3 times/d was consistently achieved only in 15.9% of the cases. Almost 60% of patients had at least one 24 hours period during which the HOB goal was never documented. This low rate of protocol compliance was not associated with acute physiology and chronic health evaluation (APACHE) II score or dependence on vasopressors. In a survey, "nurse workload" was identified as the most important factor for non-compliance with the HOB goal. In addition, the rates of compliance were significantly different (P 〈0.001) between physicians self-reporting that they either did or did not know the Institutes of Healthcare Improvement (IHI) ventilator bundle. Conclusions Low adherence to a HOB angle of ≥30° was found in this nationwide survey. Nursing workload and lack of knowledge on VAP prevention were important barriers to changin.q this practice.展开更多
基金supported by the Royal Netherlands Academy of Arts and Sciences(KNAW)(Grant No.PSA-SA-E-02)the Province of Zeeland,the Netherlands(Grant No.CoE-Buitendijks)。
文摘Understanding the sensitivity of tidal flats to environmental changes is challenging.Currently,most studies rely on process-based models to systematically explain the morphodynamic evolution of tidal flats.In this study,we proposed an alternative empirical approach to explore tidal flat dynamics using statistical indices based on long-term time series of daily surface elevation development.Surface elevation dynamic(SED)indices focus on the magnitude and period of surface elevation changes,while morphodynamic signature(MDS)indices relate sediment dynamics to environmental drivers.The statistical analyses were applied to an intervention site in the Netherlands to determine the effect of recently constructed groynes on the tidal flat.Using these analyses,we were able to(1)detect a reduction in the daily SED and(2)determine that the changes in the daily SED were predominantly caused by the reduction in wave impact between the groynes rather than the reduction in tidal currents.Overall,the presented results showed that the combination of novel statistical indices provides new insights into the trajectories of tidal flats,ecosystem functioning,and sensitivity to physical drivers(wind and tides).Finally,we suggested how the SED and MDS indices may help to explore the future trajectories and climate resilience of intertidal habitats.
文摘Confluences play a major role in the dynamics of networks of natural and man-made open channels, and field measurements on river confluences reveal that discordance in bed elevation is common.Studies of schematized confluences with a step at the interface between the tributary and the main channel bed reveal that bed elevation discordance is an important additional control for the confluence hydrodynamics.This study aimed to improve understanding of the influence of bed elevation discordance on the flow patterns and head losses in a right-angled confluence of an open channel with rectangular cross-sections.A large eddy simulation (LES)-based numerical model was set up and validated with experiments by others.Four configurations with different bed discordance ratios were investigated.The results confirm that, with increasing bed elevation discordance, the tributary streamlines at the confluence interface deviate less from the geometrical confluence angle, the extent of the recirculation zone (RZ) gets smaller, the ratio of the water depth upstream to that downstream of the confluence decreases, and the water level depression reduces.The bed elevation discordance also leads to the development of a large-scale structure in the lee of the step.Despite the appearance of the large-scale structure, the reduced extent of the RZ and associated changes in flow deflection/contraction reduce total head losses experienced by the main channel with an increase of the bed discordance ratio.It turns out that bed elevation discordance converts the lateral momentum from the tributary to streamwise momentum in the main channel more efficiently.
基金Under the auspices of National Youth Science Foundation of China(No.41001294)Key Project of National Natural Science Foundation of China(No.40930531)Research Fund of State Key Laboratory Resources and Environment Information System(No.2010KF0002SA)
文摘In China′s Loess Plateau area, gully head is the most active zone of a drainage system in gully areas. The differentiation of loess gully head follows geospatial patterns and reflects the process of the loess landform development and evolution of its drainage system to some extent. In this study, the geomorphic meaning, basic characteristics, morphological structure and the basic types of loess gully heads were systematically analysed. Then, the loess gully head′s conceptual model was established, and an extraction method based on Digital Elevation Model(DEM) for loess gully head features and elements was proposed. Through analysing the achieved statistics of loess gully head features, loess gully heads have apparently similar and different characteristics depending on the different loess landforms where they are found. The loess head characteristics reflect their growth period and evolution tendency to a certain degree, and they indirectly represent evolutionary mechanisms. In addition, the loess gully developmental stages and the evolutionary processes can be deduced by using loess gully head characteristics. This study is of great significance for development and improvement of the theoretical system for describing loess gully landforms.
文摘AIM: To analyze changes of the optic nerve head(ONH) and peripapillary region during intraocular pressure(IOP) elevation in patients using spectral domain optical coherence tomography(SD-OCT).METHODS: Both an optic disc 200×200 cube scan and a high-definition 5-line raster scan were obtained from open angle glaucoma patients presented with monocular elevation of IOP(≥30 mm Hg) using SD-OCT. Additional baseline characteristics included age, gender, diagnosis,best-corrected visual acuity, refractive error, findings of slit lamp biomicroscopy, findings of dilated stereoscopic examination of the ONH and fundus, IOP, pachymetry findings, and the results of visual field.RESULTS: The 24 patients were selected and divided into two groups: group 1 patients had no history of IOP elevation or glaucoma(n =14), and group 2 patients did have history of IOP elevation or glaucoma(n =10). In each patient, the study eye with elevated IOP was classified into group H(high), and the fellow eye was classified into group L(low). The mean deviation(MD)differed significantly between groups H and L when all eyes were considered(P =0.047) and in group 2(P =0.042), not in group 1(P =0.893). Retinal nerve fiber layer(RNFL) average thickness(P =0.050), rim area(P =0.015),vertical cup/disc ratio(P =0.011), cup volume(P =0.028),inferior quadrant RNFL thickness(P =0.017), and clockhour(1, 5, and 6) RNFL thicknesses(P =0.050, 0.012, and0.018, respectively), cup depth(P =0.008), central prelaminar layer thickness(P =0.023), mid-inferior prelaminar layer thickness(P =0.023), and nasal retinal slope(P =0.034)were significantly different between the eyes with groups H and L.CONCLUSION:RNFLaveragethickness,rim area,vertical cup/disc ratio, cup volume, inferior quadrant RNFL thickness, and clock-hour(1, 5, and 6) RNFL thicknesses significantly changed during acute IOP elevation.
文摘The impact of temperature and particle size on minimumfluidizing velocity was studied and analyzed in a small pilot scale of bubbling fluidized bed reactor.This study was devoted to providing some data about fluidization to the literature under high temperature conditions.The experiments were carried out to evaluate the minimum fluidizing velocity over a vast range of temperature levels from 20℃ to 850℃ using silica sand with a particle size of 300-425μm,425-500μm,500-600μm,and 600-710μm.Furthermore,the variation in the minimumfluidized voidage was determined experimentally at the same conditions.The experimental data revealed that the Umf directly varied with particle size and inversely with temperature,whileεmf increases slightly with temperature based on the measurements of height at incipient fluidization.However,for all particle sizes used in this test,temperatures above 700℃ has a marginal effect on Umf.The results were compared with many empirical equations,and it was found that the experimental result is still in an acceptable range of empirical equations used.In which,our findings are not well predicted by the widely accepted correlations reported in the literature.Therefore,a new predicted equation has been developed that also accounts for the affecting of mean particle size in addition to other parameters.A good mean relative deviation of 5.473% between the experimental data and the predicted values was estimated from the correlation of the effective dimensionless group.Furthermore,the experimental work revealed that the minimum fluidizing velocity was not affected by the height of the bed even at high temperature.
基金National Natural Science Foundation of China(No.41171320,41101349)National Innovation and Entrepreneurship Program(No.201210319025)
文摘This paper presents a new method for simulating the evolution of a gully head in a loess catchment with cellular automata(CA) based on the Fisher discriminant. The experimental site is an indoor loess catchment that was constructed in a fixed-intensity rainfall erosion test facility. Nine high-resolution digital elevation model(DEM) data sets were gathered by close range photogrammetry during different phases of the experiment. To simulate the evolution of the catchment gully head, we assumed the following. First, the 5th and 6th DEM data sets were used as a data source for acquiring the location of the catchment gully head and for obtaining spatial variables with GIS spatial analysis tools. Second, the Fisher discriminant was used to calculate the weight of the spatial variables to determine the transition probabilities. Third, CA model was structured to simulate the evolution of the gully head by iterative looping. The status of the cell in the CA models was dynamically updated at the end of each loop to obtain realistic results. Finally, the nearest neighbor, G-function, K-function, Moran′s I and fractal indexes were used to evaluate the model results. Overall, the CA model can be used to simulate the evolution of a loess gully head. The experiment demonstrated the advantages of the CA model which can simulate the dynamic evolution of gully head evolution in a catchment.
基金Supported by the Advance Research Project in Manned Spaceflight(No.010202)the National Natural Science Foundation of China(No.30772694)
文摘Objective: To study the changes in cardiopulmonary function induced by mid/long-term simulated microgravity with 6^° head down bed rest (HDBR), and the effects of Taikong Yangxin Prescription (太空养心方, TYP) as a countermeasure. Methods: Fourteen healthy male volunteers were randomly divided into a control group and a Chinese medicine (CM) group (7 in each group) by a random digital table based on their body weight. Both groups underwent6^° HDBR for 60 days. Subjects in the CM group received daily TYP pills and subjects in the control group received daily placebo pills. Cardiac systolic and pumping functions were measured by echocardiography before HDBR; on days 20, 42, and 57 of HDBR; and on day 3 of recovery after HDBR (R+3). Cardiopulmonary functional reserve and exercise capacity were evaluated before HDBR, on day 29, and on day R+3 by exercise testing. Results: The heart rate (HR) increased gradually during HDBR. The HR was significantly higher on day 57 than before HDBR in the control group (P〈0.05), but did not increase significantly in the CM group. The stroke volume/stroke volume index, ejection fraction, and left ventricular fractional shortening tended to decrease over time in the control group, but not in the CM group. These parameters were significantly higher in the CM group than in the control group on day 42 (P〈0.05 or P〈0.01). Exercise testing showed that maximum 02 consumption (VO2max), metabolic equivalents, relative 02 consumption (VO2), 02 pulse, and exercise duration were significantly lower on day 29 than before HDBR in the control group, but not in the CM group. Conclusions: Sixty days of 6^° HDBR induced a reduction in cardiac systolic and pumping functions, and reduced cardiopulmonary functional reserve and exercise capacity. Administration of TYP significantly improved cardiac systolic and pumping functions, and maintained cardiopulmonary functional reserve and exercise capacity.
文摘Background Elevating the head of bed (HOB) 30°-45° has been widely supported as a means of ventilator associated pneumonia (VAP) prevention. However, it was poorly adhered in clinical practice. This observational study aimed to investigate the factors impeding this simple practice at the bedside. Methods This prospective study was conducted in 33 Chinese academic hospital intensive care units (ICUs). HOB angle was measured four times daily at 5-7 hour intervals. The predefined HOB elevation goal was an angle ≥30°. Results The overall rate of achieving the HOB goal was 27.8% of the 8647 measurements in 314 patients during 2842 ventilation days. The HOB goal of ≥3 times/d was consistently achieved only in 15.9% of the cases. Almost 60% of patients had at least one 24 hours period during which the HOB goal was never documented. This low rate of protocol compliance was not associated with acute physiology and chronic health evaluation (APACHE) II score or dependence on vasopressors. In a survey, "nurse workload" was identified as the most important factor for non-compliance with the HOB goal. In addition, the rates of compliance were significantly different (P 〈0.001) between physicians self-reporting that they either did or did not know the Institutes of Healthcare Improvement (IHI) ventilator bundle. Conclusions Low adherence to a HOB angle of ≥30° was found in this nationwide survey. Nursing workload and lack of knowledge on VAP prevention were important barriers to changin.q this practice.