Objective To explore the relationship between the patterns of pronucleus and embryo development and pregnancy potential in the pronuclear stageMethods According to the number and distribution of nucleolar precursor bo...Objective To explore the relationship between the patterns of pronucleus and embryo development and pregnancy potential in the pronuclear stageMethods According to the number and distribution of nucleolar precursor bodies, the embryos at pronuclear stage were classified into 6 pronuclear patterns from 0 to 5, 16 - 18 h after in vitro fertilization (IV F) or intracytoplasmic sperm injection (ICSI). For each, pattern, the subsequent embryonic morphology and the pregnancy rate were analyzed.Results Embryos of Pattern 0 developed to significantly more embryos with good quality and higher pregnancy potential than the embryos developing from other patterns (83. 14% and 76. 11% respectively, P<0. 05). The pregnancy rate was decreased as less embryos of Pattern 0 were transferred . The pregnancy rate of the groups of only Pattern 0, with Pattern 0, and without Pattern 0 were 48. 08% , 32. 14% and 21. 28% respectively (P<0. 05).Conclusions The pronuclear patterns are of the predictive value of embryo development and pregnancy potential, which can be used as a new tool for the selection of embryos in IVF and ICSI.展开更多
To check previous findings of the most common complications among pregnancies with vanishing embryo（VE） in another actual study retropective and in group of patiens with selective embryo reduction （SER） Methods We...To check previous findings of the most common complications among pregnancies with vanishing embryo（VE） in another actual study retropective and in group of patiens with selective embryo reduction （SER） Methods We defined vanishing phenomenon as the spontaneous loss of one or more embryos after visualizing heart activity at the first trimester of pregnancy. Selective embryo reduction was performed between 8th-12th pregnancy week, through vaginal punction and aspiration of embryonic mass. Results Vanishing embryo was observed in 86 patients （18.0%）. In 61 patients （70.9%） this phenomenom happened before 9th pregnancy week. The incidence of VE increased with higher number of gestational sacs initially visualized （P〈0.03）. First trimester bleeding was more common among pregnancies with VE than in the control （P〈0.005）. The incidence of pregnancy induced hypertension was lower in pregnancies with VE than in the controls （P〈0.03）. In contrast, preterm spontaneous rupture of membranes was higher, although without statistical significance. Gestational age at delivery, mode of delivery and birth weight was similar in the group of VE and the controls （P=NS）. Conclusion All these informations may be useful in counselling patients on the prognosis and outcome of pregnancies achieved by oocyte donation.展开更多
文摘Objective To explore the relationship between the patterns of pronucleus and embryo development and pregnancy potential in the pronuclear stageMethods According to the number and distribution of nucleolar precursor bodies, the embryos at pronuclear stage were classified into 6 pronuclear patterns from 0 to 5, 16 - 18 h after in vitro fertilization (IV F) or intracytoplasmic sperm injection (ICSI). For each, pattern, the subsequent embryonic morphology and the pregnancy rate were analyzed.Results Embryos of Pattern 0 developed to significantly more embryos with good quality and higher pregnancy potential than the embryos developing from other patterns (83. 14% and 76. 11% respectively, P<0. 05). The pregnancy rate was decreased as less embryos of Pattern 0 were transferred . The pregnancy rate of the groups of only Pattern 0, with Pattern 0, and without Pattern 0 were 48. 08% , 32. 14% and 21. 28% respectively (P<0. 05).Conclusions The pronuclear patterns are of the predictive value of embryo development and pregnancy potential, which can be used as a new tool for the selection of embryos in IVF and ICSI.
文摘To check previous findings of the most common complications among pregnancies with vanishing embryo（VE） in another actual study retropective and in group of patiens with selective embryo reduction （SER） Methods We defined vanishing phenomenon as the spontaneous loss of one or more embryos after visualizing heart activity at the first trimester of pregnancy. Selective embryo reduction was performed between 8th-12th pregnancy week, through vaginal punction and aspiration of embryonic mass. Results Vanishing embryo was observed in 86 patients （18.0%）. In 61 patients （70.9%） this phenomenom happened before 9th pregnancy week. The incidence of VE increased with higher number of gestational sacs initially visualized （P〈0.03）. First trimester bleeding was more common among pregnancies with VE than in the control （P〈0.005）. The incidence of pregnancy induced hypertension was lower in pregnancies with VE than in the controls （P〈0.03）. In contrast, preterm spontaneous rupture of membranes was higher, although without statistical significance. Gestational age at delivery, mode of delivery and birth weight was similar in the group of VE and the controls （P=NS）. Conclusion All these informations may be useful in counselling patients on the prognosis and outcome of pregnancies achieved by oocyte donation.
