Objective：To evaluate the clinical value with positron emission tomography/computerized tomography（PET/CT） imaging for the detection of vulnerable plaque in atherosclerotic lesions. Methods：Sixty people with a age...Objective：To evaluate the clinical value with positron emission tomography/computerized tomography（PET/CT） imaging for the detection of vulnerable plaque in atherosclerotic lesions. Methods：Sixty people with a age of over 60[mean age （69.2 ± 7.1）years] underwent three dimension（3D） whole-body fluorine-18-2-fluoro-2-deoxy-D-glucose（^18F-FDG） PET/CT imaging and were evaluated retrospectively, including 6 cases assessed as normal and 54 cases with active atherosclerotic plaque. Fifty-four cases with SUVs and CT values in the aortic wall of high-FDG-uptake were measured retrospectively. These high-FDG-uptake cases in the aortic wall were divided into three groups according their CT value. Cases in group 1 had high uptake in atherosclerotic lesions of the aortic wall with CT value of less than 60 Hu（soft plaque）. Cases in group 2 had high uptake with CT value between 60-100 Hu （intermediate plaque）, Cases in group 3 had high uptake with CT value more than 100 Hu（calcified plaque）, Group 4 was normal. Results： In group 1, there were 42 high-FDG-uptake sites （average SUV 1.553 ± 0.486）. In group 2, there were 30 high-FDG-uptake sites（average SUV 1.393 ± 0.296）. In group 3, there were 36 high-FDG-uptake sites（average SUV 1.354 ± 0.189）. In group 4, there were 33 normal-FDG-uptake sites （average SUV was 1.102 ± 0.141）, The SUVs showed significant difference among the four groups（F = 678.909, P = 0.000）. There were also significant difference found between the normal-FDG-uptake group and the high-FDG-uptake groups（P = 0.000, 0.000, 0.001, respectively）. Conclusion：Different degrees of ^18F-FDG uptake in active large atherosclerotic plaque were shown in different stages of atherosclerotic plaque formation. The soft plaque had the highest FDG uptake in this study. This suggested that ^18F- FDG PET/CT imaging may be of great potential value in early diagnosis and monitoring of vulnerable soft plaque in atherosclerotic lesions.展开更多
Primary malignant lymphoma of the prostate is exceedingly rare.Here we report a case of a 65-year-old man who presented with increased urinary frequency,urinary urgency,and urinary incontinence for two years.Benign pr...Primary malignant lymphoma of the prostate is exceedingly rare.Here we report a case of a 65-year-old man who presented with increased urinary frequency,urinary urgency,and urinary incontinence for two years.Benign prostatic hypertrophy was suspected at primary impression.Ultrasound revealed a hypoechoic lesion of the prostate.The total serum prostate-specific antigen was within normal range.Positron emission tomography/computerized tomography(PET/CT)showed a hypermetabolic prostatic lesion.Prostate biopsy was consistent with a non-germinal center diffuse large B cell lymphoma.There was complete remission of the prostatic lesion following six cycles of chemotherapy as shown on the second PET/CT imaging.18F-fluoro-deoxy glucose PET/CT is not only a complement to conventional imaging,but also plays a significant role in the diagnosis and evaluation of treatment response of prostatic lymphoma.展开更多
目的总结Hawkeye SPECT/CT固有均匀性在日常质量控制中的校准方法,并分析其产生性能漂移的常见原因。方法选择我院2013年1月-6月Hawkeye仪器日常质控的部分数据,分析仪器的均匀性等基本情况;针对我院Hawkeye探头出现的中心视野＂亮点＂...目的总结Hawkeye SPECT/CT固有均匀性在日常质量控制中的校准方法,并分析其产生性能漂移的常见原因。方法选择我院2013年1月-6月Hawkeye仪器日常质控的部分数据,分析仪器的均匀性等基本情况;针对我院Hawkeye探头出现的中心视野＂亮点＂,而且中心视野均匀性（Center Field of View,CFOV）均匀性值偏离很大（23.17%）的现象,使用仪器提供的迭代校准程序（Iterative Calibration,ITER）进行校正。结果仪器固有均匀性通过校正后均可达到正常值（CFOV〈3.5%）。结论 Hawkeye仪器均匀性值的漂移可以通过有效的日常质量控制得到校准,通过校准可以使相机均匀性保持在较理想状态、仪器整体性能得以保证。展开更多
目的:评价单光子发射计算机断层显像(SPECT)检查过程中患者和照顾者的受照剂量及患者附近的周围剂量当量率,探讨SPECT检查过程中加强辐射防护的重要性。方法:采用In Light型光激发光(OSL)剂量计测量SPECT患者注射药物99Tcm后3 d内照顾...目的:评价单光子发射计算机断层显像(SPECT)检查过程中患者和照顾者的受照剂量及患者附近的周围剂量当量率,探讨SPECT检查过程中加强辐射防护的重要性。方法:采用In Light型光激发光(OSL)剂量计测量SPECT患者注射药物99Tcm后3 d内照顾者的个人剂量当量Hp(10),用γ剂量率仪测量SPECT患者注射药物99Tcm后距患者不同距离及不同方向的周围剂量当量率H·*(10)。结果:SPECT患者佩戴的个人剂量当量Hp(10)在0.45~1.12 m Sv之间,照顾者个人剂量当量Hp(10)在0.09~0.22 m Sv之间。注射放射性药物99Tcm后患者体表周围剂量当量率较高,一定距离处的剂量率显著下降,注射后5.5 h的周围剂量当量率降至注射后即刻测量结果的15%~25%。结论:在SPECT检查过程中,患者注射放射性药物99Tcm后其周围辐射水平较高,应加强防护及管理,提高专业工作人员的防护意识。展开更多
文摘Objective：To evaluate the clinical value with positron emission tomography/computerized tomography（PET/CT） imaging for the detection of vulnerable plaque in atherosclerotic lesions. Methods：Sixty people with a age of over 60[mean age （69.2 ± 7.1）years] underwent three dimension（3D） whole-body fluorine-18-2-fluoro-2-deoxy-D-glucose（^18F-FDG） PET/CT imaging and were evaluated retrospectively, including 6 cases assessed as normal and 54 cases with active atherosclerotic plaque. Fifty-four cases with SUVs and CT values in the aortic wall of high-FDG-uptake were measured retrospectively. These high-FDG-uptake cases in the aortic wall were divided into three groups according their CT value. Cases in group 1 had high uptake in atherosclerotic lesions of the aortic wall with CT value of less than 60 Hu（soft plaque）. Cases in group 2 had high uptake with CT value between 60-100 Hu （intermediate plaque）, Cases in group 3 had high uptake with CT value more than 100 Hu（calcified plaque）, Group 4 was normal. Results： In group 1, there were 42 high-FDG-uptake sites （average SUV 1.553 ± 0.486）. In group 2, there were 30 high-FDG-uptake sites（average SUV 1.393 ± 0.296）. In group 3, there were 36 high-FDG-uptake sites（average SUV 1.354 ± 0.189）. In group 4, there were 33 normal-FDG-uptake sites （average SUV was 1.102 ± 0.141）, The SUVs showed significant difference among the four groups（F = 678.909, P = 0.000）. There were also significant difference found between the normal-FDG-uptake group and the high-FDG-uptake groups（P = 0.000, 0.000, 0.001, respectively）. Conclusion：Different degrees of ^18F-FDG uptake in active large atherosclerotic plaque were shown in different stages of atherosclerotic plaque formation. The soft plaque had the highest FDG uptake in this study. This suggested that ^18F- FDG PET/CT imaging may be of great potential value in early diagnosis and monitoring of vulnerable soft plaque in atherosclerotic lesions.
文摘Primary malignant lymphoma of the prostate is exceedingly rare.Here we report a case of a 65-year-old man who presented with increased urinary frequency,urinary urgency,and urinary incontinence for two years.Benign prostatic hypertrophy was suspected at primary impression.Ultrasound revealed a hypoechoic lesion of the prostate.The total serum prostate-specific antigen was within normal range.Positron emission tomography/computerized tomography(PET/CT)showed a hypermetabolic prostatic lesion.Prostate biopsy was consistent with a non-germinal center diffuse large B cell lymphoma.There was complete remission of the prostatic lesion following six cycles of chemotherapy as shown on the second PET/CT imaging.18F-fluoro-deoxy glucose PET/CT is not only a complement to conventional imaging,but also plays a significant role in the diagnosis and evaluation of treatment response of prostatic lymphoma.
文摘目的总结Hawkeye SPECT/CT固有均匀性在日常质量控制中的校准方法,并分析其产生性能漂移的常见原因。方法选择我院2013年1月-6月Hawkeye仪器日常质控的部分数据,分析仪器的均匀性等基本情况;针对我院Hawkeye探头出现的中心视野＂亮点＂,而且中心视野均匀性（Center Field of View,CFOV）均匀性值偏离很大（23.17%）的现象,使用仪器提供的迭代校准程序（Iterative Calibration,ITER）进行校正。结果仪器固有均匀性通过校正后均可达到正常值（CFOV〈3.5%）。结论 Hawkeye仪器均匀性值的漂移可以通过有效的日常质量控制得到校准,通过校准可以使相机均匀性保持在较理想状态、仪器整体性能得以保证。
文摘目的:评价单光子发射计算机断层显像(SPECT)检查过程中患者和照顾者的受照剂量及患者附近的周围剂量当量率,探讨SPECT检查过程中加强辐射防护的重要性。方法:采用In Light型光激发光(OSL)剂量计测量SPECT患者注射药物99Tcm后3 d内照顾者的个人剂量当量Hp(10),用γ剂量率仪测量SPECT患者注射药物99Tcm后距患者不同距离及不同方向的周围剂量当量率H·*(10)。结果:SPECT患者佩戴的个人剂量当量Hp(10)在0.45~1.12 m Sv之间,照顾者个人剂量当量Hp(10)在0.09~0.22 m Sv之间。注射放射性药物99Tcm后患者体表周围剂量当量率较高,一定距离处的剂量率显著下降,注射后5.5 h的周围剂量当量率降至注射后即刻测量结果的15%~25%。结论:在SPECT检查过程中,患者注射放射性药物99Tcm后其周围辐射水平较高,应加强防护及管理,提高专业工作人员的防护意识。
