Brain-computer interface(BCI)technology is rapidly advancing in medical research and application.As an emerging biomedical engineering technology,it has garnered significant attention in the clinical research of brain...Brain-computer interface(BCI)technology is rapidly advancing in medical research and application.As an emerging biomedical engineering technology,it has garnered significant attention in the clinical research of brain disease diagnosis and treatment,neurological rehabilitation,and mental health.However,BCI also raises several challenges and ethical concerns in clinical research.In this article,the authors investigate and discuss three aspects of BCI in medicine and healthcare:the state of international ethical governance,multidimensional ethical challenges pertaining to BCI in clinical research,and suggestive concerns for ethical review.Despite the great potential of frontier BCI research and development in the field of medical care,the ethical challenges induced by itself and the complexities of clinical research and brain function have put forward new special fields for ethics in BCI.To ensure"responsible innovation"in BCI research in healthcare and medicine,the creation of an ethical global governance framework and system,along with special guidelines for cutting-edge BCI research in medicine,is suggested.展开更多
Brain-computer interfaces(BCI)use neural activity as a control signal to enable direct communication between the human brain and external devices.The electrical signals generated by the brain are captured through elec...Brain-computer interfaces(BCI)use neural activity as a control signal to enable direct communication between the human brain and external devices.The electrical signals generated by the brain are captured through electroencephalogram(EEG)and translated into neural intentions reflecting the user’s behavior.Correct decoding of the neural intentions then facilitates the control of external devices.Reinforcement learning-based BCIs enhance decoders to complete tasks based only on feedback signals(rewards)from the environment,building a general framework for dynamic mapping from neural intentions to actions that adapt to changing environments.However,using traditional reinforcement learning methods can have challenges such as the curse of dimensionality and poor generalization.Therefore,in this paper,we use deep reinforcement learning to construct decoders for the correct decoding of EEG signals,demonstrate its feasibility through experiments,and demonstrate its stronger generalization on motion imaging(MI)EEG data signals with high dynamic characteristics.展开更多
Brain–computer interface (BCI) systems, such as the P300 speller, enable patients to express intentions withoutnecessitating extensive training.However, the complexity of operational instructions and the slow pace of...Brain–computer interface (BCI) systems, such as the P300 speller, enable patients to express intentions withoutnecessitating extensive training.However, the complexity of operational instructions and the slow pace of characterspelling pose challenges for some patients. In this paper, an image segmentation P300 selector based on YOLOv7-mask and DeepSORT is proposed. The proposed system utilizes a camera to capture real-world objects forclassification and tracking. By applying predefined stimulation rules and object-specificmasks, the proposed systemtriggers stimuli associated with the objects displayed on the screen, inducing the generation of P300 signals in thepatient’s brain. Its video processing mechanism enables the system to identify the target the patient is focusing oneven if the object is partially obscured, overlapped, moving, or changing in number. The system alters the target’scolor display, thereby conveying the patient’s intentions to caregivers. The data analysis revealed that the selfrecognitionaccuracy of the subjects using this method was between 92% and 100%, and the cross-subject P300recognition precision was 81.9%–92.1%. This means that simple instructions such as “Do not worry, just focuson what you desire” effectively discerned the patient’s intentions using the Image Segmentation-P300 selector. Thisapproach provides cost-effective support and allows patients with communication difficulties to easily express theirneeds.展开更多
Brain-Computer interfacing(BCI)has currently added a new dimension in assistive robotics.Existing braincomputer interfaces designed for position control applications suffer from two fundamental limitations.First,most ...Brain-Computer interfacing(BCI)has currently added a new dimension in assistive robotics.Existing braincomputer interfaces designed for position control applications suffer from two fundamental limitations.First,most of the existing schemes employ open-loop control,and thus are unable to track positional errors,resulting in failures in taking necessary online corrective actions.There are examples of a few works dealing with closed-loop electroencephalography(EEG)-based position control.These existing closed-loop brain-induced position control schemes employ a fixed order link selection rule,which often creates a bottleneck preventing time-efficient control.Second,the existing brain-induced position controllers are designed to generate a position response like a traditional firstorder system,resulting in a large steady-state error.This paper overcomes the above two limitations by keeping provisions for steady-state visual evoked potential(SSVEP)induced linkselection in an arbitrary order as required for efficient control and generating a second-order response of the position-control system with gradually diminishing overshoots/undershoots to reduce steady-state errors.Other than the above,the third innovation is to utilize motor imagery and P300 signals to design the hybrid brain-computer interfacing system for the said application with gradually diminishing error-margin using speed reversal at the zero-crossings of positional errors.Experiments undertaken reveal that the steady-state error is reduced to 0.2%.The paper also provides a thorough analysis of the stability of the closed-loop system performance using the Root Locus technique.展开更多
Abstract-Common spatial pattern (CSP) algorithm is a successful tool in feature estimate of brain-computer interface (BCI). However, CSP is sensitive to outlier and may result in poor outcomes since it is based on...Abstract-Common spatial pattern (CSP) algorithm is a successful tool in feature estimate of brain-computer interface (BCI). However, CSP is sensitive to outlier and may result in poor outcomes since it is based on pooling the covariance matrices of trials. In this paper, we propose a simple yet effective approach, named common spatial pattern ensemble (CSPE) classifier, to improve CSP performance. Through division of recording channels, multiple CSP filters are constructed. By projection, log-operation, and subtraction on the original signal, an ensemble classifier, majority voting, is achieved and outlier contaminations are alleviated. Experiment results demonstrate that the proposed CSPE classifier is robust to various artifacts and can achieve an average accuracy of 83.02%.展开更多
The present study utilized motor imaginary-based brain-computer interface technology combined with rehabilitation training in 20 stroke patients. Results from the Berg Balance Scale and the Holden Walking Classificati...The present study utilized motor imaginary-based brain-computer interface technology combined with rehabilitation training in 20 stroke patients. Results from the Berg Balance Scale and the Holden Walking Classification were significantly greater at 4 weeks after treatment (P 〈 0.01), which suggested that motor imaginary-based brain-computer interface technology improved balance and walking in stroke patients.展开更多
Abstract-Two probabilistic methods are extended to research multi-class motor imagery of brain-computer interface (BCI): support vector machine (SVM) with posteriori probability (PSVM) and Bayesian linear discr...Abstract-Two probabilistic methods are extended to research multi-class motor imagery of brain-computer interface (BCI): support vector machine (SVM) with posteriori probability (PSVM) and Bayesian linear discriminant analysis with probabilistic output (PBLDA). A comparative evaluation of these two methods is conducted. The results shows that: 1) probabilistie information can improve the performance of BCI for subjects with high kappa coefficient, and 2) PSVM usually results in a stable kappa coefficient whereas PBLDA is more efficient in estimating the model parameters.展开更多
The awareness detection in patients with disorders of consciousness currently relies on behavioral observations and CRS-R tests,however,the misdiagnosis rates have been relatively high.In this study,we applied brain-c...The awareness detection in patients with disorders of consciousness currently relies on behavioral observations and CRS-R tests,however,the misdiagnosis rates have been relatively high.In this study,we applied brain-computer interface(BCI)to awareness detection with a passive auditory stimulation paradigm.12 subjects with normal hearing were invited to collect electroencephalogram(EEG)based on a BCI communication system,in which EEG signals are transmitted wirelessly.After necessary preprocessing,RBF-SVM and EEGNet were used for algorithm realization and analysis.For a single subject,RBF-SVM can distinguish his(her)name stimuli awareness with classification accuracies ranging from 60-95%.EEGNet was used to learn all subjects'data and improved accuracy to 78.04%for characteristics finding and model generalization.Moreover,we completed the supplementary analysis work from the time domain and time-frequency domain.This study applied BCI communication to human awareness detection,proposed a passive auditory paradigm,and proved the effectiveness,which could be an inspiration for brain,mental or physical diseases diagnosis and detection.展开更多
The non-stationary of the motor imagery electroencephalography(MI-EEG)signal is one of the main limitations for the development of motor imagery brain-computer interfaces(MI-BCI).The nonstationary of the MI-EEG signal...The non-stationary of the motor imagery electroencephalography(MI-EEG)signal is one of the main limitations for the development of motor imagery brain-computer interfaces(MI-BCI).The nonstationary of the MI-EEG signal and the changes of the experimental environment make the feature distribution of the testing set and training set deviates,which reduces the classification accuracy of MI-BCI.In this paper,we propose a Kullback–Leibler divergence(KL)-based transfer learning algorithm to solve the problem of feature transfer,the proposed algorithm uses KL to measure the similarity between the training set and the testing set,adds support vector machine(SVM)classification probability to classify and weight the covariance,and discards the poorly performing samples.The results show that the proposed algorithm can significantly improve the classification accuracy of the testing set compared with the traditional algorithms,especially for subjects with medium classification accuracy.Moreover,the algorithm based on transfer learning has the potential to improve the consistency of feature distribution that the traditional algorithms do not have,which is significant for the application of MI-BCI.展开更多
The tactile P300 brain-computer interface( BCI) is related to the somatosensory perception and response of the human brain,and is different from visual or audio BCIs. Recently,several studies focused on the tactile st...The tactile P300 brain-computer interface( BCI) is related to the somatosensory perception and response of the human brain,and is different from visual or audio BCIs. Recently,several studies focused on the tactile stimuli delivered to different parts of the human body. Most of these stimuli were symmetrically bilateral.Only a fewstudies explored the influence of tactile stimuli laterality.In the current study,we extensively tested the performance of a vibrotactile BCI system using ipsilateral stimuli and bilateral stimuli.Two vibrotactile P300-based paradigms were tested. The target stimuli were located on the left and right forearms for the left forearm and right forearm( LFRF) paradigm,and on the left forearm and calf for the left forearm and left calf( LFLC)paradigm. Ten healthy subjects participated in this study. Our experiments and analysis showed that the bilateral paradigm( LFRF) elicited larger P300 amplitude and achieved significantly higher classification accuracy than the ipsilateral paradigm( LFLC). However, both paradigms achieved classification accuracies higher than 70% after the completion of several trials on average,which was usually regarded as the minimum accuracy level required for BCI system to be deemed useful.展开更多
The Brain-Computer Interfaces(BCIs)had been proposed and used in therapeutics for decades.However,the need of time-consuming calibration phase and the lack of robustness,which are caused by little-labeled data,are res...The Brain-Computer Interfaces(BCIs)had been proposed and used in therapeutics for decades.However,the need of time-consuming calibration phase and the lack of robustness,which are caused by little-labeled data,are restricting the advance and application of BCI,especially for the BCI based on motor imagery(MI).In this paper,we reviewed the recent development in the machine learning algorithm used in the MI-based BCI,which may provide potential solutions for addressing the issue.We classified these algorithms into two categories,namely,and enhancing the representation and expanding the training set.Specifically,these methods of enhancing the representation of features collected from few EEG trials are based on extracting features of multiple bands,regularization,and so on.The methods of expanding the training dataset include approaches of transfer learning(session to session transfer,subject to subject transfer)and generating artificial EEG data.The result of these techniques showed the resolution of the challenges to some extent.As a developing research area,the study of BCI algorithms in little-labeled data is increasingly requiring the advancement of human brain physiological structure research and more transfer learning algorithms research.展开更多
R. Penrose and S. Hameroff have proposed an idea that the brain can attain high efficient quantum computation by functioning of microtubular structure of neurons in the cytoskelton of biological cells, including neuro...R. Penrose and S. Hameroff have proposed an idea that the brain can attain high efficient quantum computation by functioning of microtubular structure of neurons in the cytoskelton of biological cells, including neurons of the brain. But Tegmark estimated the duration of coherence of a quantum state in a warm wet brain to be on the order of 10>–13 </supseconds, which is far smaller than the one tenth of a second associated with consciousness. Contrary to his calculation, it can be shown that the microtubule in a biological brain can perform computation satisfying the time scale required for quantum computation to achieve large quantum bits calculation compared with the conventional silicon processors even at the room temperature from the assumption that tunneling photons are superluminal particles called tachyons. According to the non-local property of tachyons, it is considered that the tachyon field created inside the brain has the capability to exert an influence around the space outside the brain and it functions as a macroscopic quantum dynamical system to meditate the long-range physical correlations with the surrounding world. From standpoint of the brain model based on superluminal tunneling photons, the authors theoretically searched for the possibility to realize the brain-computer interface that allows paralyzed patient to operate computers by their thoughts and they obtained the positive result for its realization from the experiments conducted by using the prototype of a brain-computer interface system.展开更多
In this paper, we proposed a new concept: depth of drowsiness, which can more precisely describe the drowsiness than existing binary description. A set of effective markers for drowsiness: normalized band norm was suc...In this paper, we proposed a new concept: depth of drowsiness, which can more precisely describe the drowsiness than existing binary description. A set of effective markers for drowsiness: normalized band norm was successfully developed. These markers are invariant from voltage amplitude of brain waves, eliminating the need for calibrating the voltage output of the brain-computer interface devices. A new polling algorithm was designed and implemented for computing the depth of drowsiness. The time cost of data acquisition and processing for each estimate is about one second, which is well suited for real-time applications. Test results with a portable brain-computer interface device show that the depth of drowsiness computed by the method in this paper is generally invariant from ages of test subjects and sensor channels (P3 and C4). The comparison between experiment and computing results indicate that the new method is noticeably better than one of the recent methods in terms of accuracy for predicting the drowsiness.展开更多
As a non-invasive neurophysiologieal index for brain-computer interface (BCI), electroencephalogram (EEG) attracts much attention at present. In order to have a portable BCI, a simple and efficient pre-amplifier i...As a non-invasive neurophysiologieal index for brain-computer interface (BCI), electroencephalogram (EEG) attracts much attention at present. In order to have a portable BCI, a simple and efficient pre-amplifier is crucial in practice. In this work, a preamplifier based on the characteristics of EEG signals is designed, which consists of a highly symmetrical input stage, low-pass filter, 50 Hz notch filter and a post amplifier. A prototype of this EEG module is fabricated and EEG data are obtained through an actual experiment. The results demonstrate that the EEG preamplifier will be a promising unit for BCI in the future.展开更多
We perceive that some Brain-Computer Interface (BCI) researchers believe in totally different origins of invasive and non-invasive electrical BCI signals. Based on available literature we argue, however, that although...We perceive that some Brain-Computer Interface (BCI) researchers believe in totally different origins of invasive and non-invasive electrical BCI signals. Based on available literature we argue, however, that although invasive and non-invasive BCI signals are different, the underlying origin of electrical BCIs signals is the same.展开更多
Transferring the contralateral C7 nerve root to the median or radial nerve has become an important means of repairing brachial plexus nerve injury.However,outcomes have been disappointing.Electroencephalography(EEG)-b...Transferring the contralateral C7 nerve root to the median or radial nerve has become an important means of repairing brachial plexus nerve injury.However,outcomes have been disappointing.Electroencephalography(EEG)-based human-machine interfaces have achieved promising results in promoting neurological recovery by controlling a distal exoskeleton to perform functional limb exercises early after nerve injury,which maintains target muscle activity and promotes the neurological rehabilitation effect.This review summarizes the progress of research in EEG-based human-machine interface combined with contralateral C7 transfer repair of brachial plexus nerve injury.Nerve transfer may result in loss of nerve function in the donor area,so only nerves with minimal impact on the donor area,such as the C7 nerve,should be selected as the donor.Single tendon transfer does not fully restore optimal joint function,so multiple functions often need to be reestablished simultaneously.Compared with traditional manual rehabilitation,EEG-based human-machine interfaces have the potential to maximize patient initiative and promote nerve regeneration and cortical remodeling,which facilitates neurological recovery.In the early stages of brachial plexus injury treatment,the use of an EEG-based human-machine interface combined with contralateral C7 transfer can facilitate postoperative neurological recovery by making full use of the brain’s computational capabilities and actively controlling functional exercise with the aid of external machinery.It can also prevent disuse atrophy of muscles and target organs and maintain neuromuscular junction effectiveness.Promoting cortical remodeling is also particularly important for neurological recovery after contralateral C7 transfer.Future studies are needed to investigate the mechanism by which early movement delays neuromuscular junction damage and promotes cortical remodeling.Understanding this mechanism should help guide the development of neurological rehabilitation strategies for patients with brachial plexus injury.展开更多
Brain computer interface(BCI)systems permit individuals with motor disorders to utilize their thoughts as a mean to control external devices.BCI is a promising interdisciplinary field that gained the attention of many...Brain computer interface(BCI)systems permit individuals with motor disorders to utilize their thoughts as a mean to control external devices.BCI is a promising interdisciplinary field that gained the attention of many researchers.Yet,the development of BCI systems is facing several challenges,such as network lifetime.The Medium Access Control(MAC)Protocol is the bottle-neck of network reliability.There are many MAC protocols that can be utilized for dependable transmission in BCI applications by altering their control parameters.However,modifying these parameters is another source of concern due to the scarcity in knowledge about the effect of modification.Also,there is still no instrument that can receive and actualize these parameters on transmitters embedded inside the cerebrum.In this paper,we propose two novel MAC protocols using passive UHF-RFID,the proposed protocols provide efficient and reliable communication between the transmitters and the receiver.The UHF-RFID transmitters were used because they are energy efficient which makes them compatible with BCI application.The first protocol is designed for the EEG signals.While the second protocol was designed for the ECoG signals.The evaluation results showed the validity of the proposed protocols in terms of network performance.The results also proved that the protocols are suitable and reliable for designing efficient BCI applications.展开更多
A brain-computer interface (BCI) facilitates bypassing the peripheral nervous system and directly communicating with surrounding devices. Navigation technology using BCI has developed-from exploring the prototype para...A brain-computer interface (BCI) facilitates bypassing the peripheral nervous system and directly communicating with surrounding devices. Navigation technology using BCI has developed-from exploring the prototype paradigm in the virtual environment (VE) to accurately completing the locomotion intention of the operator in the form of a powered wheelchair or mobile robot in a real environment. This paper summarizes BCI navigation applications that have been used in both real and VEs in the past 20 years. Horizontal comparisons were conducted between various paradigms applied to BCI and their unique signal-processing methods. Owing to the shift in the control mode from synchronous to asynchronous, the development trend of navigation applications in the VE was also reviewed. The contrast between high level commands and low-level commands is introduced as the main line to review the two major applications of BCI navigation in real environments: mobile robots and unmanned aerial vehicles (UAVs). Finally, applications of BCI navigation to scenarios outside the laboratory;research challenges, including human factors in navigation application interaction design;and the feasibility of hybrid BCI for BCI navigation are discussed in detail.展开更多
Recent advances in neuroelectrode interface materials and modification technologies are reviewed. Brain-computer interface is the new method of human-computer interaction, which not only can realise the exchange of in...Recent advances in neuroelectrode interface materials and modification technologies are reviewed. Brain-computer interface is the new method of human-computer interaction, which not only can realise the exchange of information between the human brain and external devices, but also provides a brand-new means for the diagnosis and treatment of brain-related diseases. The neural electrode interface part of brain-computer interface is an important area for electrical, optical and chemical signal transmission between brain tissue system and external electronic devices, which determines the performance of brain-computer interface. In order to solve the problems of insufficient flexibility, insufficient signal recognition ability and insufficient biocompatibility of traditional rigid electrodes, researchers have carried out extensive studies on the neuroelectrode interface in terms of materials and modification techniques. This paper introduces the biological reactions that occur in neuroelectrodes after implantation into brain tissue and the decisive role of the electrode interface for electrode function. Following this, the latest research progress on neuroelectrode materials and interface materials is reviewed from the aspects of neuroelectrode materials and modification technologies, firstly taking materials as a clue, and then focusing on the preparation process of neuroelectrode coatings and the design scheme of functionalised structures.展开更多
User experience is understood in so many ways,like a one on one interaction(subjective views),online surveys and questionnaires.This is simply so get the user’s implicit response,this paper demonstrates the underlyin...User experience is understood in so many ways,like a one on one interaction(subjective views),online surveys and questionnaires.This is simply so get the user’s implicit response,this paper demonstrates the underlying user emotion on a particular interface such as the webpage visual content based on the context of familiarisation to convey users’emotion on the interface using emoji,we integrated physiological readings and eye movement behaviour to convey user emotion on the visual centre field of a web interface.The physiological reading is synchronised with the eye tracker to obtain correlating user interaction,and emoticons are used as a form of emotion conveyance on the interface.The eye movement prediction is obtained through a control system’s loop and is represented by different color display of gaze points(GT)that detects a particular user’s emotion on the webpage interface.These are interpreted by the emoticons.Result shows synchronised readings which correlates to area of interests(AOI)of the webpage and user emotion.These are prototypical instances of authentic user response execution for a computer interface and to easily identify user response without user subjective response for better and easy design decisions.展开更多
基金supported by the Ministry of Science and Tech-nology of the People's Republic of China(2021ZD0201900),Project 5(2021ZD0201905).
文摘Brain-computer interface(BCI)technology is rapidly advancing in medical research and application.As an emerging biomedical engineering technology,it has garnered significant attention in the clinical research of brain disease diagnosis and treatment,neurological rehabilitation,and mental health.However,BCI also raises several challenges and ethical concerns in clinical research.In this article,the authors investigate and discuss three aspects of BCI in medicine and healthcare:the state of international ethical governance,multidimensional ethical challenges pertaining to BCI in clinical research,and suggestive concerns for ethical review.Despite the great potential of frontier BCI research and development in the field of medical care,the ethical challenges induced by itself and the complexities of clinical research and brain function have put forward new special fields for ethics in BCI.To ensure"responsible innovation"in BCI research in healthcare and medicine,the creation of an ethical global governance framework and system,along with special guidelines for cutting-edge BCI research in medicine,is suggested.
文摘Brain-computer interfaces(BCI)use neural activity as a control signal to enable direct communication between the human brain and external devices.The electrical signals generated by the brain are captured through electroencephalogram(EEG)and translated into neural intentions reflecting the user’s behavior.Correct decoding of the neural intentions then facilitates the control of external devices.Reinforcement learning-based BCIs enhance decoders to complete tasks based only on feedback signals(rewards)from the environment,building a general framework for dynamic mapping from neural intentions to actions that adapt to changing environments.However,using traditional reinforcement learning methods can have challenges such as the curse of dimensionality and poor generalization.Therefore,in this paper,we use deep reinforcement learning to construct decoders for the correct decoding of EEG signals,demonstrate its feasibility through experiments,and demonstrate its stronger generalization on motion imaging(MI)EEG data signals with high dynamic characteristics.
文摘Brain–computer interface (BCI) systems, such as the P300 speller, enable patients to express intentions withoutnecessitating extensive training.However, the complexity of operational instructions and the slow pace of characterspelling pose challenges for some patients. In this paper, an image segmentation P300 selector based on YOLOv7-mask and DeepSORT is proposed. The proposed system utilizes a camera to capture real-world objects forclassification and tracking. By applying predefined stimulation rules and object-specificmasks, the proposed systemtriggers stimuli associated with the objects displayed on the screen, inducing the generation of P300 signals in thepatient’s brain. Its video processing mechanism enables the system to identify the target the patient is focusing oneven if the object is partially obscured, overlapped, moving, or changing in number. The system alters the target’scolor display, thereby conveying the patient’s intentions to caregivers. The data analysis revealed that the selfrecognitionaccuracy of the subjects using this method was between 92% and 100%, and the cross-subject P300recognition precision was 81.9%–92.1%. This means that simple instructions such as “Do not worry, just focuson what you desire” effectively discerned the patient’s intentions using the Image Segmentation-P300 selector. Thisapproach provides cost-effective support and allows patients with communication difficulties to easily express theirneeds.
文摘Brain-Computer interfacing(BCI)has currently added a new dimension in assistive robotics.Existing braincomputer interfaces designed for position control applications suffer from two fundamental limitations.First,most of the existing schemes employ open-loop control,and thus are unable to track positional errors,resulting in failures in taking necessary online corrective actions.There are examples of a few works dealing with closed-loop electroencephalography(EEG)-based position control.These existing closed-loop brain-induced position control schemes employ a fixed order link selection rule,which often creates a bottleneck preventing time-efficient control.Second,the existing brain-induced position controllers are designed to generate a position response like a traditional firstorder system,resulting in a large steady-state error.This paper overcomes the above two limitations by keeping provisions for steady-state visual evoked potential(SSVEP)induced linkselection in an arbitrary order as required for efficient control and generating a second-order response of the position-control system with gradually diminishing overshoots/undershoots to reduce steady-state errors.Other than the above,the third innovation is to utilize motor imagery and P300 signals to design the hybrid brain-computer interfacing system for the said application with gradually diminishing error-margin using speed reversal at the zero-crossings of positional errors.Experiments undertaken reveal that the steady-state error is reduced to 0.2%.The paper also provides a thorough analysis of the stability of the closed-loop system performance using the Root Locus technique.
基金supported by the National Natural Science Foundation of China under Grant No. 30525030, 60701015, and 60736029.
文摘Abstract-Common spatial pattern (CSP) algorithm is a successful tool in feature estimate of brain-computer interface (BCI). However, CSP is sensitive to outlier and may result in poor outcomes since it is based on pooling the covariance matrices of trials. In this paper, we propose a simple yet effective approach, named common spatial pattern ensemble (CSPE) classifier, to improve CSP performance. Through division of recording channels, multiple CSP filters are constructed. By projection, log-operation, and subtraction on the original signal, an ensemble classifier, majority voting, is achieved and outlier contaminations are alleviated. Experiment results demonstrate that the proposed CSPE classifier is robust to various artifacts and can achieve an average accuracy of 83.02%.
基金the National Natural Science Foundation of China,No.60970062the Shanghai Pujiang Program,No.09PJ1410200
文摘The present study utilized motor imaginary-based brain-computer interface technology combined with rehabilitation training in 20 stroke patients. Results from the Berg Balance Scale and the Holden Walking Classification were significantly greater at 4 weeks after treatment (P 〈 0.01), which suggested that motor imaginary-based brain-computer interface technology improved balance and walking in stroke patients.
基金supported by the National Natural Science Foundation of China under Grant No. 30525030, 60701015, and 60736029.
文摘Abstract-Two probabilistic methods are extended to research multi-class motor imagery of brain-computer interface (BCI): support vector machine (SVM) with posteriori probability (PSVM) and Bayesian linear discriminant analysis with probabilistic output (PBLDA). A comparative evaluation of these two methods is conducted. The results shows that: 1) probabilistie information can improve the performance of BCI for subjects with high kappa coefficient, and 2) PSVM usually results in a stable kappa coefficient whereas PBLDA is more efficient in estimating the model parameters.
基金supported by the Science and Technology Commission of Shanghai Municipality(STCSM)Research Fund(21JC1405300)to Fan Minthe National Key Research and Development Program of China(2018YFC0831102)sponsored by the Shanghai Key Research Laboratory of NSAI。
文摘The awareness detection in patients with disorders of consciousness currently relies on behavioral observations and CRS-R tests,however,the misdiagnosis rates have been relatively high.In this study,we applied brain-computer interface(BCI)to awareness detection with a passive auditory stimulation paradigm.12 subjects with normal hearing were invited to collect electroencephalogram(EEG)based on a BCI communication system,in which EEG signals are transmitted wirelessly.After necessary preprocessing,RBF-SVM and EEGNet were used for algorithm realization and analysis.For a single subject,RBF-SVM can distinguish his(her)name stimuli awareness with classification accuracies ranging from 60-95%.EEGNet was used to learn all subjects'data and improved accuracy to 78.04%for characteristics finding and model generalization.Moreover,we completed the supplementary analysis work from the time domain and time-frequency domain.This study applied BCI communication to human awareness detection,proposed a passive auditory paradigm,and proved the effectiveness,which could be an inspiration for brain,mental or physical diseases diagnosis and detection.
文摘The non-stationary of the motor imagery electroencephalography(MI-EEG)signal is one of the main limitations for the development of motor imagery brain-computer interfaces(MI-BCI).The nonstationary of the MI-EEG signal and the changes of the experimental environment make the feature distribution of the testing set and training set deviates,which reduces the classification accuracy of MI-BCI.In this paper,we propose a Kullback–Leibler divergence(KL)-based transfer learning algorithm to solve the problem of feature transfer,the proposed algorithm uses KL to measure the similarity between the training set and the testing set,adds support vector machine(SVM)classification probability to classify and weight the covariance,and discards the poorly performing samples.The results show that the proposed algorithm can significantly improve the classification accuracy of the testing set compared with the traditional algorithms,especially for subjects with medium classification accuracy.Moreover,the algorithm based on transfer learning has the potential to improve the consistency of feature distribution that the traditional algorithms do not have,which is significant for the application of MI-BCI.
基金National Key Research and Development Program,China(No.2017YFB13003002)National Natural Science Foundation of China(Nos.61573142,61773164,91420302)Programme of Introducing Talents of Discipline to Universities(the 111 Project)(No.B17017)
文摘The tactile P300 brain-computer interface( BCI) is related to the somatosensory perception and response of the human brain,and is different from visual or audio BCIs. Recently,several studies focused on the tactile stimuli delivered to different parts of the human body. Most of these stimuli were symmetrically bilateral.Only a fewstudies explored the influence of tactile stimuli laterality.In the current study,we extensively tested the performance of a vibrotactile BCI system using ipsilateral stimuli and bilateral stimuli.Two vibrotactile P300-based paradigms were tested. The target stimuli were located on the left and right forearms for the left forearm and right forearm( LFRF) paradigm,and on the left forearm and calf for the left forearm and left calf( LFLC)paradigm. Ten healthy subjects participated in this study. Our experiments and analysis showed that the bilateral paradigm( LFRF) elicited larger P300 amplitude and achieved significantly higher classification accuracy than the ipsilateral paradigm( LFLC). However, both paradigms achieved classification accuracies higher than 70% after the completion of several trials on average,which was usually regarded as the minimum accuracy level required for BCI system to be deemed useful.
文摘The Brain-Computer Interfaces(BCIs)had been proposed and used in therapeutics for decades.However,the need of time-consuming calibration phase and the lack of robustness,which are caused by little-labeled data,are restricting the advance and application of BCI,especially for the BCI based on motor imagery(MI).In this paper,we reviewed the recent development in the machine learning algorithm used in the MI-based BCI,which may provide potential solutions for addressing the issue.We classified these algorithms into two categories,namely,and enhancing the representation and expanding the training set.Specifically,these methods of enhancing the representation of features collected from few EEG trials are based on extracting features of multiple bands,regularization,and so on.The methods of expanding the training dataset include approaches of transfer learning(session to session transfer,subject to subject transfer)and generating artificial EEG data.The result of these techniques showed the resolution of the challenges to some extent.As a developing research area,the study of BCI algorithms in little-labeled data is increasingly requiring the advancement of human brain physiological structure research and more transfer learning algorithms research.
文摘R. Penrose and S. Hameroff have proposed an idea that the brain can attain high efficient quantum computation by functioning of microtubular structure of neurons in the cytoskelton of biological cells, including neurons of the brain. But Tegmark estimated the duration of coherence of a quantum state in a warm wet brain to be on the order of 10>–13 </supseconds, which is far smaller than the one tenth of a second associated with consciousness. Contrary to his calculation, it can be shown that the microtubule in a biological brain can perform computation satisfying the time scale required for quantum computation to achieve large quantum bits calculation compared with the conventional silicon processors even at the room temperature from the assumption that tunneling photons are superluminal particles called tachyons. According to the non-local property of tachyons, it is considered that the tachyon field created inside the brain has the capability to exert an influence around the space outside the brain and it functions as a macroscopic quantum dynamical system to meditate the long-range physical correlations with the surrounding world. From standpoint of the brain model based on superluminal tunneling photons, the authors theoretically searched for the possibility to realize the brain-computer interface that allows paralyzed patient to operate computers by their thoughts and they obtained the positive result for its realization from the experiments conducted by using the prototype of a brain-computer interface system.
文摘In this paper, we proposed a new concept: depth of drowsiness, which can more precisely describe the drowsiness than existing binary description. A set of effective markers for drowsiness: normalized band norm was successfully developed. These markers are invariant from voltage amplitude of brain waves, eliminating the need for calibrating the voltage output of the brain-computer interface devices. A new polling algorithm was designed and implemented for computing the depth of drowsiness. The time cost of data acquisition and processing for each estimate is about one second, which is well suited for real-time applications. Test results with a portable brain-computer interface device show that the depth of drowsiness computed by the method in this paper is generally invariant from ages of test subjects and sensor channels (P3 and C4). The comparison between experiment and computing results indicate that the new method is noticeably better than one of the recent methods in terms of accuracy for predicting the drowsiness.
基金supported by the National Natural Science Foundation of China under Grant No. 60571019the University of Electronic Science and Technology of China Youth Foundation under Grant No. L08010901JX0772.
文摘As a non-invasive neurophysiologieal index for brain-computer interface (BCI), electroencephalogram (EEG) attracts much attention at present. In order to have a portable BCI, a simple and efficient pre-amplifier is crucial in practice. In this work, a preamplifier based on the characteristics of EEG signals is designed, which consists of a highly symmetrical input stage, low-pass filter, 50 Hz notch filter and a post amplifier. A prototype of this EEG module is fabricated and EEG data are obtained through an actual experiment. The results demonstrate that the EEG preamplifier will be a promising unit for BCI in the future.
文摘We perceive that some Brain-Computer Interface (BCI) researchers believe in totally different origins of invasive and non-invasive electrical BCI signals. Based on available literature we argue, however, that although invasive and non-invasive BCI signals are different, the underlying origin of electrical BCIs signals is the same.
基金supported by the National Natural Science Foundation of China, No.31771322(to PXZ)the Natural Science Foundation of Beijing, No.7212121(to PXZ)+2 种基金Shenzhen Science and Technology Plan Project, No.JCYJ20190806162205278(to PXZ)Funds for Severe Trauma Standardized Treatment, No.SZSM202011001(to PXZ)a grant from National Center for Trauma Medicine, Beijing, China, No.BMU2020 XY005-01(to PXZ)
文摘Transferring the contralateral C7 nerve root to the median or radial nerve has become an important means of repairing brachial plexus nerve injury.However,outcomes have been disappointing.Electroencephalography(EEG)-based human-machine interfaces have achieved promising results in promoting neurological recovery by controlling a distal exoskeleton to perform functional limb exercises early after nerve injury,which maintains target muscle activity and promotes the neurological rehabilitation effect.This review summarizes the progress of research in EEG-based human-machine interface combined with contralateral C7 transfer repair of brachial plexus nerve injury.Nerve transfer may result in loss of nerve function in the donor area,so only nerves with minimal impact on the donor area,such as the C7 nerve,should be selected as the donor.Single tendon transfer does not fully restore optimal joint function,so multiple functions often need to be reestablished simultaneously.Compared with traditional manual rehabilitation,EEG-based human-machine interfaces have the potential to maximize patient initiative and promote nerve regeneration and cortical remodeling,which facilitates neurological recovery.In the early stages of brachial plexus injury treatment,the use of an EEG-based human-machine interface combined with contralateral C7 transfer can facilitate postoperative neurological recovery by making full use of the brain’s computational capabilities and actively controlling functional exercise with the aid of external machinery.It can also prevent disuse atrophy of muscles and target organs and maintain neuromuscular junction effectiveness.Promoting cortical remodeling is also particularly important for neurological recovery after contralateral C7 transfer.Future studies are needed to investigate the mechanism by which early movement delays neuromuscular junction damage and promotes cortical remodeling.Understanding this mechanism should help guide the development of neurological rehabilitation strategies for patients with brachial plexus injury.
文摘Brain computer interface(BCI)systems permit individuals with motor disorders to utilize their thoughts as a mean to control external devices.BCI is a promising interdisciplinary field that gained the attention of many researchers.Yet,the development of BCI systems is facing several challenges,such as network lifetime.The Medium Access Control(MAC)Protocol is the bottle-neck of network reliability.There are many MAC protocols that can be utilized for dependable transmission in BCI applications by altering their control parameters.However,modifying these parameters is another source of concern due to the scarcity in knowledge about the effect of modification.Also,there is still no instrument that can receive and actualize these parameters on transmitters embedded inside the cerebrum.In this paper,we propose two novel MAC protocols using passive UHF-RFID,the proposed protocols provide efficient and reliable communication between the transmitters and the receiver.The UHF-RFID transmitters were used because they are energy efficient which makes them compatible with BCI application.The first protocol is designed for the EEG signals.While the second protocol was designed for the ECoG signals.The evaluation results showed the validity of the proposed protocols in terms of network performance.The results also proved that the protocols are suitable and reliable for designing efficient BCI applications.
基金Supported by Key-Area Research and Development Program of Guangdong Province (2019B010149001)the National NaturalScience Foundation of China (61960206007)the 111 Project (B18005)
文摘A brain-computer interface (BCI) facilitates bypassing the peripheral nervous system and directly communicating with surrounding devices. Navigation technology using BCI has developed-from exploring the prototype paradigm in the virtual environment (VE) to accurately completing the locomotion intention of the operator in the form of a powered wheelchair or mobile robot in a real environment. This paper summarizes BCI navigation applications that have been used in both real and VEs in the past 20 years. Horizontal comparisons were conducted between various paradigms applied to BCI and their unique signal-processing methods. Owing to the shift in the control mode from synchronous to asynchronous, the development trend of navigation applications in the VE was also reviewed. The contrast between high level commands and low-level commands is introduced as the main line to review the two major applications of BCI navigation in real environments: mobile robots and unmanned aerial vehicles (UAVs). Finally, applications of BCI navigation to scenarios outside the laboratory;research challenges, including human factors in navigation application interaction design;and the feasibility of hybrid BCI for BCI navigation are discussed in detail.
基金the National Key Research and Development Program,No.2021YFB3800800the National Natural Science Foundation of China,Nos.31922041,32171341,32301113,the 111 Project,No.B14018+3 种基金the Science and Technology Innovation Project and Excellent Academic Leader Project of Shanghai Science and Technology Committee,Nos.21S31901500,21XD1421100the National Postdoctoral Program for Innovative Talents,No.BX20230122the Shanghai Sailing Program,No.23YF1409700the China Postdoctoral Science Foundation,No.D100-5R-22114.
文摘Recent advances in neuroelectrode interface materials and modification technologies are reviewed. Brain-computer interface is the new method of human-computer interaction, which not only can realise the exchange of information between the human brain and external devices, but also provides a brand-new means for the diagnosis and treatment of brain-related diseases. The neural electrode interface part of brain-computer interface is an important area for electrical, optical and chemical signal transmission between brain tissue system and external electronic devices, which determines the performance of brain-computer interface. In order to solve the problems of insufficient flexibility, insufficient signal recognition ability and insufficient biocompatibility of traditional rigid electrodes, researchers have carried out extensive studies on the neuroelectrode interface in terms of materials and modification techniques. This paper introduces the biological reactions that occur in neuroelectrodes after implantation into brain tissue and the decisive role of the electrode interface for electrode function. Following this, the latest research progress on neuroelectrode materials and interface materials is reviewed from the aspects of neuroelectrode materials and modification technologies, firstly taking materials as a clue, and then focusing on the preparation process of neuroelectrode coatings and the design scheme of functionalised structures.
文摘User experience is understood in so many ways,like a one on one interaction(subjective views),online surveys and questionnaires.This is simply so get the user’s implicit response,this paper demonstrates the underlying user emotion on a particular interface such as the webpage visual content based on the context of familiarisation to convey users’emotion on the interface using emoji,we integrated physiological readings and eye movement behaviour to convey user emotion on the visual centre field of a web interface.The physiological reading is synchronised with the eye tracker to obtain correlating user interaction,and emoticons are used as a form of emotion conveyance on the interface.The eye movement prediction is obtained through a control system’s loop and is represented by different color display of gaze points(GT)that detects a particular user’s emotion on the webpage interface.These are interpreted by the emoticons.Result shows synchronised readings which correlates to area of interests(AOI)of the webpage and user emotion.These are prototypical instances of authentic user response execution for a computer interface and to easily identify user response without user subjective response for better and easy design decisions.