An Intervention Study of Language Cognition and Emotional Speech Community Method for Children’s Speech Disorders

Speech disorders are a common type of childhood disease.Through experimental intervention,this study aims to improve the vocabulary comprehension levels and language ability of children with speech disorders through the language cognition and emotional speech community method.We also conduct a statistical analysis of the inter-ventional effect.Among children with speech disorders in Dongguan City,224 were selected and grouped accord-ing to their receptive language ability and IQ.The 112 children in the experimental group(EG)received speech therapy with language cognitive and emotional speech community,while the 112 children in the control group(CG)only received conventional treatment.After six months of experimental intervention,the Peabody Picture Vocabulary Test-Revised(PPVT-R)was used to test the language ability of the two groups.Overall,we employed a quantitative approach to obtain numerical values,examine the variables identified,and test hypotheses.Further-more,we used descriptive statistics to explore the research questions related to the study and statistically describe the overall distribution of the demographic variables.The statistical t-test was used to analyze the data.The data shows that after intervention through language cognition and emotional speech community therapy,the PPVT-R score of the EG was significantly higher than that of the CG.Therefore,we conclude that there is a significant difference in language ability between the EG and CG after the therapy.Although both groups improved,the post-therapy language level of EG is significantly higher than that of CG.The total effective rate in EG is higher than CG,and the difference is statistically significant(p<0.05).Therefore,we conclude that the language cogni-tion and emotional speech community method is effective as an interventional treatment of children’s speech dis-orders and that it is more effective than traditional treatment methods.

Neural and Cognitive Markers and Regulation of Emotion in Depression: A Mini-Review and a Short Case Report

In the presented short clinical case of depression, the constructs of Research Domain Criteria (RDoC) of loss (negative valence systems) and cognitive control (cognitive systems) have been operationalized. It has been concluded that a normal cognitive control of emotion, requiring the functional and structural integrity of prefrontal cortex (PFC) and orbitofrontal cortex (OFC), is lacking in depression, but its amelioration can be achieved through the implementation of cognitive remediation/rehabilitation programs. A mini-review on neural and cognitive markers and regulation of emotion in depression is previously presented.

Embodied Emotion--Turn from Traditional to PostCognitive Perspectives

This literature review on the research of embodied emotion addresses the aspects of the concepts of embodied emotion, the various theories or theses on the embodied emotion abroad and at home, some comments based on the literature are elicited and the discussions about the future research topics on embodied emotion are proposed.

Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy

Gestational exposure to PM_(2.5) is associated with adverse postnatal outcomes.PM_(2.5) can enter alveoli by using intratracheal instillation,even penetrate through lung cells into the blood circulation.Subsequently,they are transferred across the placenta and fetal blood brain barrier,causing the adverse birth outcomes of offspring.This study demonstrated that the gestational exposure resulted in cognitive and emotional disorders in female offspring although the offspring were not exposed to PM_(2.5).Placental metabolic pathways modulated fetal brain development and played a pivotal role for maternal-placentalfetal interactions in the fetal programming of adult behavioral and mental disorders.Samples of fetus,offspring hippocampus and placenta from the mice exposed to PM_(2.5) were investigated using a comprehensive approach including mass spectrometry-based lipidomics and three-dimensional imaging.The exposure induced the neuro-degeneration in hippocampus,impairment of placental cytoarchitecture,and reprogramming of lipidome,which might affect the modulation of maternal-fetal cross-talk and result in the behavior disorders of offspring.The variation of spatial distribution of lipids was profoundly affected in dorsal pallium and hippocampal formation regions of fetal brain,offspring hippocampus,as well as labyrinth and junctional zones of placenta.The abundance alteration of lipid markers associated with neurodegenerative diseases was validated in transgenic mouse model with Alzheimer’s disease and human cerebrospinal fluid from patients with Parkinson’s disease.The finding could help with the selection of more suitable heterogeneous-related substructures targeting PM_(2.5) exposure and the exploration of PM_(2.5)-induced toxicological effects on neurodegenerative diseases.

Active fraction combination from Liuwei Dihuang decoction improves adult hippocampal neurogenesis and neurogenic microenvironment in cranially irradiated mice

OBJECTIVE Cranial radiotherapy is clinically used in the treatment of brain tumors;however,the consequent cognitive and emotional dysfunctions seriously impair the life quality of patients.LW-AFC,an active fraction combination extracted from classical traditional Chinese medicine prescription Liuwei Dihuang decoction,can improve cognitive and emotional dysfunctions in many animal models;however,the protective effect of LW-AFC on cranial irradiation-induced cognitive and emotional dysfunctions has not been reported.Recent studies indicate that impairment of adult hippocampal neurogenesis(AHN)and alterations of the neurogenic microenvironment in the hippocampus constitute critical factors in cognitive and emotional dysfunctions following cranial irradiation.Here,our research further investigated the potential protective effects and mechanisms of LW-AFC on cranial irradiation-induced cognitive and emotional dysfunctions in mice.METHODS LW-AFC(1.6 g·kg^(-1))was intragastrically administered to mice for 14 d before cranial irradiation(7 Gyγ-ray).AHN was examined by quantifying the number of proliferative neural stem cells and immature neurons in the dorsal and ventral hippocampus.The contextual fear conditioning test,open field test,and tail suspension test were used to assess cognitive and emotional functions in mice.To detect the change of the neurogenic microenvironment,colorimetry and multiplex bead analysis were performed to measure the level of oxidative stress,neurotrophic and growth factors,and inflammation in the hippocampus.RESULTS LW-AFC exerted beneficial effects on the contextual fear memory,anxiety behavior,and depression behavior in irradiated mice.Moreover,LW-AFC increased the number of proliferative neural stem cells and immature neurons in the dorsal hippocampus,displaying a regional specificity of neurogenic response.For the neurogenic microenvironment,LW-AFC significantly increased the contents of superoxide dismutase,glutathione peroxidase,glutathione,and catalase and decreased the content of malondialdehyde in the hippocampus of irradiated mice,accompanied by the increase in brain-derived neurotrophic factor,insulin-like growth factor-1,and interleukin-4 content.Together,LW-AFC improved cognitive and emotional dysfunctions,promoted AHN preferentially in the dorsal hippocampus,and ameliorated disturbance in the neurogenic microenvironment in irradiated mice.CONCLUSION LW-AFC ameliorates cranial irradiation-induced cognitive and emotional dysfunctions,and the underlying mechanisms are mediated by promoting AHN in the dorsal hippocampus and improving the neurogenic microenvironment.LW-AFC might be a promising therapeutic agent to treat cognitive and emotional dysfunctions in patients receiving cranial radiotherapy.

Kenotomy,the Domain of Creative Thinking

Creativity is designative for the mankind,distinguishing it among the other species.Everyone is born with the affinity to speculate the perceived reality—overlaying it by his own imagination,inventing a playful use for the encountered items and refreshing extant ideas by new approaches,creating new mental outcome.The perceived world is not enough for the human mind,which challenges the given reality,animated by the need for questing and creatively exploring beyond it.As a result,the history of humanity is a history of realized inventions and different visions.If the creativity is an organic part of the human nature,why are so few mature people creative?

Guest Editorial New and Interdisciplinary Approaches to Language and Cognition

This Special Section on Language and Cognition of Journal of Electronic Science and Technology（JEST） presents a collective of state-of-theart interdisciplinary research on language and cognition. It features empirical and theoretical studies on cognitive approaches to language, using a variety of methodological approaches, from behavioral measures to neuroimaging. The topics discussed are varied,ranging from language comprehension and acquisition to the language-emotion interactions, reflecting marked broadening of the research agenda in this field. We invite yet more integrated research to move the field forward.

Violence-related behaviors among adolescents and its association with cognitive emotion regulation strategies

Background:Adolescent violence is now regarded as a major public health concern.Despite growing interest in psychographic risk factors for violent behavior,few studies have explored the role of strategies to regulate cognitive emotion in adolescents.This study aimed to investigate the prevalence of adolescent violence behaviors and to identify the relationship between specific strategies to regulate cognitive emotion and forms of violent behavior.Methods:We cross-sectionally surveyed 3315 students in grades 7 to 10 using anonymous,self-reporting questionnaires to examine strategies to regulate cognitive emotion and violence-related behaviors in young adolescents.A logistic regression model was used to identify the relationship between specific violent behaviors and strategies to regulate cognitive emotion.Results:The most commonly reported type of violent behavior was verbal attack(48.6%),while 7.1%of students were involved in fi ghts and 2.4%had been injured in fights.Boys were involved in all forms of violent behavior studied,and did so significantly more often than girls(P<0.05).Logistic regression revealed that six cognitive emotion strategies(self-blame,rumination,planning,reappraisal,catastrophisizing,and blaming others)were associated with violent behaviors,of which catastrophisizing was the most significant factor of all violent behaviors examined that were infl uenced by this strategy.Conclusions:Violence-related behaviors,especially verbal attacks,were common among adolescents.Several cognitive emotion regulation strategies were positively associated with specific violent behaviors,but catastrophisizing was strongly related to all forms of violent behavior.Thus,programs targeting adolescent violence must address this and other maladaptive cognitive emotion regulation strategies.