Biodiversity,large trees,and environmental conditions such as climate and soil have important effects on forest carbon stocks.However,recent studies in temperate forests suggest that the relative importance of these f...Biodiversity,large trees,and environmental conditions such as climate and soil have important effects on forest carbon stocks.However,recent studies in temperate forests suggest that the relative importance of these factors depends on tree mycorrhizal associations,whereby large-tree effects may be driven by ectomycorrhizal(EM)trees,diversity effects may be driven by arbuscular mycorrhizal(AM)trees,and environment effects may depend on differential climate and soil preferences of AM and EM trees.To test this hypothesis,we used forest-inventory data consisting of over 80,000 trees from 631 temperate-forest plots(30 m×30 m)across Northeast China to examine how biodiversity(species diversity and ecological uniqueness),large trees(top 1%of tree diameters),and environmental factors(climate and soil nutrients)differently regulate aboveground carbon stocks of AM trees,EM trees,and AM and EM trees combined(i.e.total aboveground carbon stock).We found that large trees had a positive effect on both AM and EM tree carbon stocks.However,biodiversity and environmental factors had opposite effects on AM vs.EM tree carbon stocks.Specifically,the two components of biodiversity had positive effects on AM tree carbon stocks,but negative effects on EM tree carbon stocks.Environmental heterogeneity(mean annual temperature and soil nutrients)also exhibited contrasting effects on AM and EM tree carbon stocks.Consequently,for the total carbon stock,the positive large-tree effect far surpasses the diversity and environment effect.This is mainly because when integrating AM and EM tree carbon stock into total carbon stock,the opposite diversity-effect(also environment-effect)on AM vs.EM tree carbon stock counteracts each other while the consistent positive large-tree effect on AM and EM tree carbon stock is amplified.In summary,this study emphasized a mycorrhizal viewpoint to better understand the determinants of overarching aboveground carbon profile across regional forests.展开更多
To investigate whether outdoor activities have an improvement effect on the emotions of young people and the differences in the impact of outdoor activities on the emotions of young people under different landscape en...To investigate whether outdoor activities have an improvement effect on the emotions of young people and the differences in the impact of outdoor activities on the emotions of young people under different landscape environmental conditions,the participating students are asked to engage in outdoor activities in different landscape environments and divided into four groups.Each group is assigned to engage in outdoor activities in four types of landscape areas:open lawn area,low shrub area,dense forest area,and waterfront area.The activities include outdoor yoga and making leaf mandalas.The results show that outdoor yoga has the best effect on reducing pulse and blood pressure and regulating emotions in open lawn area and waterfront area,followed by leaf mantras in waterfront area and outdoor yoga in dense forest area.However,both activities have no significant effect in low shrub area.展开更多
The hydrogenic donor impurity states and intersubband optical absorption spectra in monolayer transition metal dichalcogenides(ML TMDs) under dielectric environments are theoretically investigated based on a two-dimen...The hydrogenic donor impurity states and intersubband optical absorption spectra in monolayer transition metal dichalcogenides(ML TMDs) under dielectric environments are theoretically investigated based on a two-dimensional(2D)nonorthogonal associated Laguerre basis set. The 2D quantum confinement effect together with the strongly reduced dielectric screening results in the strong attractive Coulomb potential between electron and donor ion, with exceptionally large impurity binding energy and huge intersubband oscillator strength. These lead to the strong interaction of the electron with light in a 2D regime. The intersubband optical absorption spectra exhibit strong absorption lines of the non-hydrogenic Rydberg series in the mid-infrared range of light. The strength of the Coulomb potential can be controlled by changing the dielectric environment. The electron affinity difference leads to charge transfer between ML TMD and the dielectric environment, generating the polarization-electric field in ML TMD accompanied by weakening the Coulomb interaction strength. The larger the dielectric constant of the dielectric environment, the more the charge transfer is, accompanied by the larger polarization-electric field and the stronger dielectric screening. The dielectric environment is shown to provide an efficient tool to tune the wavelength and output of the mid-infrared intersubband devices based on ML TMDs.展开更多
Using newly developed methods and software, association mapping was conducted for chromium content and total sugar in tobacco leaf, based on four-omics datasets. Our objective was to collect data on genotype and pheno...Using newly developed methods and software, association mapping was conducted for chromium content and total sugar in tobacco leaf, based on four-omics datasets. Our objective was to collect data on genotype and phenotype for 60 leaf samples at four developmental stages, from three plant architectural positions and for three cultivars that were grown in two locations. Association mapping was conducted to detect genetic variants at quantitative trait SNP(QTS) loci, quantitative trait transcript(QTT) differences,quantitative trait protein(QTP) variability, and quantitative trait metabolite(QTM) changes,which can be summarized as QTX locus variation. The total heritabilities of the four-omics loci for both traits tested were 23.60% for epistasis and 15.26% for treatment interaction.Epistasis and environment × treatment interaction had important impacts on complex traits at all-omics levels. For decreasing chromium content and increasing total sugar in tobacco leaf, six methylated loci can be directly used for marker-assisted selection, and expression of ten QTTs, seven QTPs and six QTMs can be modified by selection or cultivation.展开更多
The aim of this study explored the importance of colour application on clothing and investigated whether there is a preference of colour on clothing among children under hospital environment. A modified colour associa...The aim of this study explored the importance of colour application on clothing and investigated whether there is a preference of colour on clothing among children under hospital environment. A modified colour associated test based on the Luster Color Test was used to carry out the survey. Fifty child patients aged four to sixteen were asked to look at two specially designed colour cards and to name their preferences and associations on each of the colour.展开更多
Alzheimer’s disease (AD) is a common neurodegenerative disease, its main clinical symptoms are the progressive decline of cognitive and memory functions. Enriched Environment (EE) achieves the goal of improving brain...Alzheimer’s disease (AD) is a common neurodegenerative disease, its main clinical symptoms are the progressive decline of cognitive and memory functions. Enriched Environment (EE) achieves the goal of improving brain cognitive reserve by enhancing the multi-directional stimulation on movement, sensory and cognitive systems of animals. And EE can regulate the levels of various trophic factors in the brain, promote synaptic regeneration and enhance neural plasticity to reduce the loss of neurons induced by inflammation. At present, there is still no effective treatment for AD and the clinical intervention drug is expensive. So it is essential to actively explore non-drug treatment. This review will explain the effects of EE on learning ability, memory ability and mental behavior in AD, and provide a new direction for the treatment and rehabilitation of AD.展开更多
Despite significant advances in our understanding of the molecular pathogenesis of liver cancer and the availability of novel pharmacotherapies,liver cancer remains the fourth leading cause of cancer-related mortality...Despite significant advances in our understanding of the molecular pathogenesis of liver cancer and the availability of novel pharmacotherapies,liver cancer remains the fourth leading cause of cancer-related mortality worldwide.Tumor relapse,resistance to current anti-cancer drugs,metastasis,and organ toxicity are the major challenges that prevent considerable improvements in patient survival and quality of life.Calculus bovis(CB),an ancient Chinese medicinal drug,has been used to treat various pathologies,including stroke,convulsion,epilepsy,pain,and cancer.In this editorial,we discuss the research findings recently published by Huang et al on the therapeutic effects of CB in inhibiting the development of liver cancer.Utilizing the comprehensive transcriptomic analyses,in vitro experiments,and in vivo studies,the authors demonstrated that CB treatment inhibits the tumor-promoting M2 phenotype of tumor-associated macrophages via downregulating Wnt pathway.While multiple studies have been performed to explore the molecular mechanisms regulated by CB,this study uniquely shows its role in modulating the M2 phenotype of macrophages present within the tumor microenvironment.This study opens new avenues of future investigations aimed at investigating this drug’s efficacy in various mouse models including the effects of combination therapy,and against drug-resistant tumors.展开更多
Urban waterfronts are important gateways that reflect a city’s image and characteristics.Evaluating waterfront vitality and its influencing factors is critical for guiding urban waterfront planning and redevelopment....Urban waterfronts are important gateways that reflect a city’s image and characteristics.Evaluating waterfront vitality and its influencing factors is critical for guiding urban waterfront planning and redevelopment.Hourly human movement data,provided by the Baidu Heatmap,were used to explore the weekday and weekend urban vitality spatial distribution characteristics of the waterfronts of the Qinhuai River in Nanjing.Global(ordinary least squares)and local(multiscale geographically weighted regression)models revealed the influence of physicaleenvironmental characteristics(objective)and spatial experience evaluation factors(subjective)on urban vitality.(1)The Qinhuai River waterfront urban vitality agglomeration characteristics were similar between weekdays and weekends,and the core vitality areas were distributed in the dense tourism,commercial,and residential areas along the river.(2)The evaluation of catering experience had the strongest positive correlation with vitality,whereas the waterfront distance had the strongest negative correlation.(3)The influence of each factor on waterfront vitality in the study area exhibited considerable spatial differences,with attenuation trends observed from the east-to-west river sections.This study shows the urban vitality distribution characteristics of the Qinhuai River waterfront spaces.Exploring the influence of physicaleenvironmental and spatial evaluation factors on the vitality distribution can provide a scientific basis and reference for urban waterfront planning and redevelopment focusing on cultivating vitality.展开更多
基金supported by the Key Research Program of Frontier Sciences,Chinese Academy of Sciences(Grant ZDBS-LY-DQC019)the National Key Research and Development Program of China(2023YFE0124300)+4 种基金the National Natural Science Foundation of China(32301344)Major Program of Institute of Applied EcologyChinese Academy of Sciences(IAEMP202201)supported by grants from the U.S.National Science Foundation(DEB 2240431)the Seeding Projects for Enabling Excellence and Distinction(SPEED)Program at Washington University in St.Louis。
文摘Biodiversity,large trees,and environmental conditions such as climate and soil have important effects on forest carbon stocks.However,recent studies in temperate forests suggest that the relative importance of these factors depends on tree mycorrhizal associations,whereby large-tree effects may be driven by ectomycorrhizal(EM)trees,diversity effects may be driven by arbuscular mycorrhizal(AM)trees,and environment effects may depend on differential climate and soil preferences of AM and EM trees.To test this hypothesis,we used forest-inventory data consisting of over 80,000 trees from 631 temperate-forest plots(30 m×30 m)across Northeast China to examine how biodiversity(species diversity and ecological uniqueness),large trees(top 1%of tree diameters),and environmental factors(climate and soil nutrients)differently regulate aboveground carbon stocks of AM trees,EM trees,and AM and EM trees combined(i.e.total aboveground carbon stock).We found that large trees had a positive effect on both AM and EM tree carbon stocks.However,biodiversity and environmental factors had opposite effects on AM vs.EM tree carbon stocks.Specifically,the two components of biodiversity had positive effects on AM tree carbon stocks,but negative effects on EM tree carbon stocks.Environmental heterogeneity(mean annual temperature and soil nutrients)also exhibited contrasting effects on AM and EM tree carbon stocks.Consequently,for the total carbon stock,the positive large-tree effect far surpasses the diversity and environment effect.This is mainly because when integrating AM and EM tree carbon stock into total carbon stock,the opposite diversity-effect(also environment-effect)on AM vs.EM tree carbon stock counteracts each other while the consistent positive large-tree effect on AM and EM tree carbon stock is amplified.In summary,this study emphasized a mycorrhizal viewpoint to better understand the determinants of overarching aboveground carbon profile across regional forests.
基金Research Program Special Project of Tianjin Municipal Education Commission(Psychological Health Education)(2020ZXXL-GX03G)Ten Hundred Thousand Application Project of Tianjin Social Science.
文摘To investigate whether outdoor activities have an improvement effect on the emotions of young people and the differences in the impact of outdoor activities on the emotions of young people under different landscape environmental conditions,the participating students are asked to engage in outdoor activities in different landscape environments and divided into four groups.Each group is assigned to engage in outdoor activities in four types of landscape areas:open lawn area,low shrub area,dense forest area,and waterfront area.The activities include outdoor yoga and making leaf mandalas.The results show that outdoor yoga has the best effect on reducing pulse and blood pressure and regulating emotions in open lawn area and waterfront area,followed by leaf mantras in waterfront area and outdoor yoga in dense forest area.However,both activities have no significant effect in low shrub area.
文摘The hydrogenic donor impurity states and intersubband optical absorption spectra in monolayer transition metal dichalcogenides(ML TMDs) under dielectric environments are theoretically investigated based on a two-dimensional(2D)nonorthogonal associated Laguerre basis set. The 2D quantum confinement effect together with the strongly reduced dielectric screening results in the strong attractive Coulomb potential between electron and donor ion, with exceptionally large impurity binding energy and huge intersubband oscillator strength. These lead to the strong interaction of the electron with light in a 2D regime. The intersubband optical absorption spectra exhibit strong absorption lines of the non-hydrogenic Rydberg series in the mid-infrared range of light. The strength of the Coulomb potential can be controlled by changing the dielectric environment. The electron affinity difference leads to charge transfer between ML TMD and the dielectric environment, generating the polarization-electric field in ML TMD accompanied by weakening the Coulomb interaction strength. The larger the dielectric constant of the dielectric environment, the more the charge transfer is, accompanied by the larger polarization-electric field and the stronger dielectric screening. The dielectric environment is shown to provide an efficient tool to tune the wavelength and output of the mid-infrared intersubband devices based on ML TMDs.
基金supported by the National Basic Research Program of China (2011CB109306 and 2009CB118404)the Program of Introducing Talents of Discipline to Universities of China ("111" Project, B06014)Research Programs (CNTC-D2011100, CNTC-[2012]146, NY-[2011]3047, QKHRZ [2013] 02)
文摘Using newly developed methods and software, association mapping was conducted for chromium content and total sugar in tobacco leaf, based on four-omics datasets. Our objective was to collect data on genotype and phenotype for 60 leaf samples at four developmental stages, from three plant architectural positions and for three cultivars that were grown in two locations. Association mapping was conducted to detect genetic variants at quantitative trait SNP(QTS) loci, quantitative trait transcript(QTT) differences,quantitative trait protein(QTP) variability, and quantitative trait metabolite(QTM) changes,which can be summarized as QTX locus variation. The total heritabilities of the four-omics loci for both traits tested were 23.60% for epistasis and 15.26% for treatment interaction.Epistasis and environment × treatment interaction had important impacts on complex traits at all-omics levels. For decreasing chromium content and increasing total sugar in tobacco leaf, six methylated loci can be directly used for marker-assisted selection, and expression of ten QTTs, seven QTPs and six QTMs can be modified by selection or cultivation.
文摘The aim of this study explored the importance of colour application on clothing and investigated whether there is a preference of colour on clothing among children under hospital environment. A modified colour associated test based on the Luster Color Test was used to carry out the survey. Fifty child patients aged four to sixteen were asked to look at two specially designed colour cards and to name their preferences and associations on each of the colour.
文摘Alzheimer’s disease (AD) is a common neurodegenerative disease, its main clinical symptoms are the progressive decline of cognitive and memory functions. Enriched Environment (EE) achieves the goal of improving brain cognitive reserve by enhancing the multi-directional stimulation on movement, sensory and cognitive systems of animals. And EE can regulate the levels of various trophic factors in the brain, promote synaptic regeneration and enhance neural plasticity to reduce the loss of neurons induced by inflammation. At present, there is still no effective treatment for AD and the clinical intervention drug is expensive. So it is essential to actively explore non-drug treatment. This review will explain the effects of EE on learning ability, memory ability and mental behavior in AD, and provide a new direction for the treatment and rehabilitation of AD.
基金Supported by the National Institutes of Health grants,No.K99HL146954 and No.R00HL146954the UTHSC College of Pharmacy Research Seed Grant award,No.2023.
文摘Despite significant advances in our understanding of the molecular pathogenesis of liver cancer and the availability of novel pharmacotherapies,liver cancer remains the fourth leading cause of cancer-related mortality worldwide.Tumor relapse,resistance to current anti-cancer drugs,metastasis,and organ toxicity are the major challenges that prevent considerable improvements in patient survival and quality of life.Calculus bovis(CB),an ancient Chinese medicinal drug,has been used to treat various pathologies,including stroke,convulsion,epilepsy,pain,and cancer.In this editorial,we discuss the research findings recently published by Huang et al on the therapeutic effects of CB in inhibiting the development of liver cancer.Utilizing the comprehensive transcriptomic analyses,in vitro experiments,and in vivo studies,the authors demonstrated that CB treatment inhibits the tumor-promoting M2 phenotype of tumor-associated macrophages via downregulating Wnt pathway.While multiple studies have been performed to explore the molecular mechanisms regulated by CB,this study uniquely shows its role in modulating the M2 phenotype of macrophages present within the tumor microenvironment.This study opens new avenues of future investigations aimed at investigating this drug’s efficacy in various mouse models including the effects of combination therapy,and against drug-resistant tumors.
基金funded by the Arts Project of the National Social Science Foundation of China(No.18CG197).
文摘Urban waterfronts are important gateways that reflect a city’s image and characteristics.Evaluating waterfront vitality and its influencing factors is critical for guiding urban waterfront planning and redevelopment.Hourly human movement data,provided by the Baidu Heatmap,were used to explore the weekday and weekend urban vitality spatial distribution characteristics of the waterfronts of the Qinhuai River in Nanjing.Global(ordinary least squares)and local(multiscale geographically weighted regression)models revealed the influence of physicaleenvironmental characteristics(objective)and spatial experience evaluation factors(subjective)on urban vitality.(1)The Qinhuai River waterfront urban vitality agglomeration characteristics were similar between weekdays and weekends,and the core vitality areas were distributed in the dense tourism,commercial,and residential areas along the river.(2)The evaluation of catering experience had the strongest positive correlation with vitality,whereas the waterfront distance had the strongest negative correlation.(3)The influence of each factor on waterfront vitality in the study area exhibited considerable spatial differences,with attenuation trends observed from the east-to-west river sections.This study shows the urban vitality distribution characteristics of the Qinhuai River waterfront spaces.Exploring the influence of physicaleenvironmental and spatial evaluation factors on the vitality distribution can provide a scientific basis and reference for urban waterfront planning and redevelopment focusing on cultivating vitality.