Conjunctions and/or Disjunctions： Radical Empiricism in the History of Philosophy

William James challenged the traditions of British Empiricism （Hume） on one hand and German Idealism （Kant and Hegel） on the other. James＇ ＂Radical Empiricism＂ is a via media （＂middle road＂） between these divergent positions. His central points of contention are the ontological status of relationships and the correct analysis of experience. British Empiricism leaves us with a world of separate, particular facts, based on atomic sense impressions. Idealists, on the other hand, claim that all worldly phenomena are conjoined by one rational principle. According to James＇ account, neither side recognizes that both conjunctive and disjunctive relations are integral to experience. Furthermore, James＇ critique proved to influence A. N. Whitehead＇s philosophy of experience and orientation toward Hume and Kant. This essay situates James＇ philosophy in this polemical and historical context.

Claude Bernard’s experimental method of head and hand

According to Claude Bernard,each of the sciences investigates different natural phenomena using experimental methods unique to that science,especially experimental medicine.However,Bernard also argued that these sciences share a“common”experimental method that depends on both the“head”and the“hand”.What he accomplished with his common method is to combine both rationalism and empiricism-head and hand,respectively-to undergird the unity of the experimental sciences while maintaining their plurality.Bernard’s experimental method as articulated in terms of the rational head and the empirical hand metaphor is relevant today to the unity of science vs.pluralism debate,as well as to the rationalism vs.empiricism debate and to the hypothesis-driven vs.data-driven science debate-each of which is explored in turn after briefly reconstructing Bernard’s philosophy of experimental medicine.And his metaphor of head and hand provides a means for examining the natural and biomedical sciences as they evolve with regard to specialization.

Three Evolutions of the Landscape Cognitive Model from the Perspective of Philosophy

Looking back at the history of landscape design, there are various styles and schools as well as numerous design concepts. From the perspective of philosophical epistemology, landscape design has experienced three periods, namely, apriorism, empiricism and transcendentalism. Combining the design phenomena in the history of garden design, this paper sorted out the evolution of landscape design in terms of methodology, epistemology and instrumentalism, in order to speculate on the macroscopic trajectory of the evolution of landscape cognitive model.

Paradigms and Methodologies for Knowledge Building

A diversity of methodologies can be utilized for knowledge building in social sciences, particularly in education. Nevertheless, in order to give meaning to the research findings and progressively create theories, an awareness of the epistemological framework appears to be necessary. The aim of this article is to present the main epistemological paradigms and their coherent correspondence with respective ontologies and corresponding methodologies. This article supports and describes four paradigms or epistemological traditions: logic empiricism, constructivism, conceptualism or Aristotelian tradition, and phenomenology. Understanding the diverse possible epistemologies as well as the coherence with methodologies is a necessary step for presenting well-informed research. Knowledge building requires comparison, replication, generalization or integration of results in theories, and all these processes need the critical instance of the epistemological and methodological coherence. Additionally some concrete examples of methodologies have been detailed to illustrate the diversity of available ways of knowledge building in education. The Review of Educational Theory, as a new journal that aims to create a scientific community, will increase the research quality by enhancing the epistemological and methodological awareness of their pieces of research.

A Diagnostic Tool for Identification of Etiologies of Fever of Unknown Origin in Adult Patients

The diagnosis and treatment of fever of unknown origin (FUO) are huge challenges to clinicians.Separating the etiologies of FUO into infectious and non-infectious disease is conducive to clinical physicians not only on making decisions rapidly concerning the prescription of suitable antibiotics but also on further analysis of the final diagnosis.In order to develop and validate a diagnostic tool to efficiently distinguish the etiologies of adult FUO patients as infectious or non-infectious disease,FUO patients from the departments of infectious disease and internal medicine in three Chinese tertiary hospitals were enrolled retrospectively and prospectively.By using polynomial logistic regression analysis,the diagnostic formula and the associated scoring system were developed.The variables included in this diagnostic formula were from clinical evaluations and common laboratory examinations.The proposed tool could discriminate infectious and noninfectious causes of FUO with an area under receiver operating characteristic curve (AUC) of 0.83,sensitivity of 0.80 and specificity of 0.75.This diagnosis tool could predict the infectious and non-infectious causes of FUO in the validation cohort with an AUC of 0.79,sensitivity of 0.79 and specificity of 0.70.The results suggested that this diagnostic tool could be a reliable tool to discriminate between infectious and non-infectious causes of FUO.

Establishment of a Predictive Model Related to Pathogen Invasion for Infectious Diseases and Its Diagnostic Value in Fever of Unknown Origin

The present study aimed to establish a list of parameters indicative of pathogen invasion and develop a predictive model to distinguish the etiologies of fever of unknown origin (FUO) into infectious and non-infectious causes.From January 2014 to September 2017,431 patients with FUO were prospectively enrolled in the study population.This study established a list of 26 variables from the following 4aspects:host factors,epidemiological factors,behavioral factors,and iatrogenic factors.Predefined predicted variables were included in a multivariate logistic regression analysis to develop a predictive model.The predictive model and the corresponding scoring system were developed using data from the confirmed diagnoses and 9 variables were eventually identified.These factors were incorporated into the predictive model.This model discriminated between infectious and non-infectious causes of FUO with an AUC of 0.72,sensitivity of 0.71, and specificity of 0.63.The predictive model and corresponding scoring system based on factors concerning pathogen invasion appear to be reliable screening tools to discriminate between infectious and non-infectious causes of FUO.

Prevention of necrotizing enterocolitis in premature infants——an updated review

Necrotizing enterocolitis(NEC) is among the most common and devastating diseases encountered in premature infants, yet the true etiology continues to be poorly understood despite decades of research. Recently, gut bacterial dysbiosis has been proposed as a risk factor for the development of NEC. Based on this theory, several best clinical practices designed to reduce the risk of NEC have been proposed and/or implemented. This review summarizes the results of recent clinical trials and meta-analyses that support some of the existing clinical practices for reducing the risk of NEC in premature infants. It is evident that human milk feeding can reduce the incidence of NEC. While most of the studies demonstrated that probiotic supplementation can significantly reduce the incidence of NEC in premature infants, there are still some concerns regarding the quality, safety, optimal dosage, and treatment duration of probiotic preparations. Antibiotic prophylaxis does not reduce the incidence of NEC, and prolonged initial empirical use of antibiotics might in fact increase the risk of NEC for high-risk premature infants. Lastly, standardized feeding protocols are strongly recommended, both for prevention of postnatal growth restriction and NEC.

Opinion: Chemical--Mesoscopics..for the Mesoparticles Reactivity Explanation

The estimation of chemical particles reactivity and the determination of chemical reactions direction are the actual theme in new scientific trend-Chemical Mesoscopics.Paper includes the proposal about the using the theory of free energy linear dependence from physical organic chemistry and their applications for prognosis of reactions flowing.The semi-empiric constants is given according to mesoscopic physics definitions as well as the transformed Kolmogorov-Avrami equation is discussed.It is the development of Chemical Mesoscopics for organic reactivity estimation including nanostructures reactivity.

The efficacy of empiric arterial embolization for treating severe hemoptysis

Aim: Purpose of the study was to investigate the efficacy of empiric arterial embolization in order to achieve hemostasis in patients with massive hemoptysis. Materials and Methods: A retrospective review of histories and interventional studies of 56 patients (40 male, 16 female, median age 57 years;range, 16 - 83 years) referred for endovascular treatment of massive hemoptysis over a period of 17 years. Arteries supposed to supply the bleeding bronchoalveolar sections were embolized with particles in all cases. Digital subtraction angiographical (DSA) studies were analyzed with respect to the morphology of the embolized arteries. Arteries were termed pathologic when they were either hypertrophic or supplied hypervascular lung sections as well as actively bleeding branches. Empiric embolization was defined as endovascular occlusion of arteries without visible contrast-material extravasation on DSA studies. Results: Continuing hemoptysis was encountered in one (25%) of 4 patients with active contrast extravasation and in 11 (21%) of 52 empirically embolized patients: Six (19%) of 32 patients with pathologic arteries visible on aortography, 3 (18%) of 17 with pathologic arteries visible by selective arteriography and 2 (67%) of 3 with no visible pathologic arteries. From 6 patients (11%, 5 male, 1 female) who died within 30 days after embolization, 3 suffered from tuberculosis while 3 had malignant tumors. Three had ongoing hemoptysis. One patient died of multiple organ failure caused by post-interventional paraplegia and consecutive pneumonia. Conclusion: In patients with hemoptysis, empirical embolization is effective when pathologic bronchial arteries can be identified by DSA.

真理的自由和自由的真理——德勒兹对康德思想的超越

哲学是为了寻求关于人的真理,或者,哲学是人的思想所留下的轨迹?康德提出思想是朝向真理前行,是为了认识人自己。然而,康德哲学所塑造的人的形象在德勒兹眼中却成了人自由的羁绊,是对于思想的束缚。为了理解思想在康德和德勒兹之间的转变,论者在这里考察了德勒兹对于康德的理性主义的批判,以及德勒兹对于思想自由的论述。

The Practical Historical Approach:A Review of the Principles and Methods of Fact-First History

This article defines and defends"the practical historical approach",a long-established approach to history which prizes the critical treatment of sources and,above all else,the presentation and assessment of accurate information about the past.This approach appreciates the value of historical fact in its own right,not just when it furnishes an opportunity to build theories or to prove points.The article does not aim to make a theoretical case for empiricist history,arguing instead that the old philosophy-driven debates about empiricism have little bearing on the practice of historical research and writing.It prefers to make a practical defence of certain critical methods and habits of thought which are now sometimes dismissed as old-fashioned.It draws on a series of historians'handbooks dating from 1889 to 1980,in which the methods and principles of the practical approach were worked out and refined,and it identifies the main principles and techniques of this approach,many of which derive from the German“scientific"historical tradition,and which furnish historians with a powerful apparatus for critically analyzing sources.The article also has a polemical angle,arguing that the practical historical approach could profitably be taught more consciously inuniversities.

Theoretical Sources of Charles Morris' s Semiotics

Charles Morris constructs his semiotics on the basis of scientific empiricism. The latter is the combination of three schools of thought, namely, formalism, empiricism and pragmatism. The former similarly consists of three parts, i.e., syntactics, semantics and pragmatics. The three philosophical schools of thought contribute to the three major components of Morris' s semiotics.

A Feeling for Literature:Empirical Stylistics

In this paper I examine the contribution of feelings to the reader's literary understanding,focussing on aspects of response that have been studied through the use of empirical methods.I first provide a review of several components of feeling that have been found of importance in literary reading.I then focus on the role of feelings at several different levels.At the level of the stylistics of the text I consider studies of response to foregrounding and phonetic iconicity.At an intermediate level I look at a study of how feelings help to characterize episodes in narrative.Lastly I present a study at the largest scale(comprising a whole short story) of the role of feeling in elaborating an unreliable narrator,working largely through the comments of one reader.As a whole,the paper offers evidence for the range and variety of literary phenomena that draw on the capacities of feeling.

对总体的反抗与超越的经验主义——论罗森茨威格对列维纳斯的贡献

导言罗森茨威格(Franz Rosenzweig)与列维纳斯(Emmanuel Levinas)是现代犹太神哲学的两个重要人物。列维纳斯在哲学与神学许多思想主题上深受罗森茨威格的影响,最为突出的一点是"反抗总体"(opposition to the idea of totality)。列维纳斯多次在其著作和访谈中明确罗森茨威格在这个主题上给予的贡献,①并在三篇文章中专门介绍和解读罗森茨威格,反复强调罗森茨威格在反抗总体上对自己的影响。

Nursing staff capacity plays a crucial role in compliance to empiric antibiotic treatment within the first hour in patients with septic shock

To the Editor: Sepsis and septic shock are a leading cause of intensive care unit (ICU) admissions and induce significant morbidity and mortality.[1,2] Early propitiate antibiotics administration is significantly associated with improved survival in sepsis and septic shock[3,4] which is recommended by the international guidelines.[5] However, the compliance to sepsis protocols remains very low.[6] Nurses, who play a vital role in carrying out physician orders, are likely associated with the compliance to empiric antibiotic administration. Phua et al[7] showed that nurses occupy an essential and conscious position as brokers of doctors’ antibiotic decisions. In addition, other studies also demonstrated that nurse-led protocols were an effective, safe, and sustainable method for achieving early antibiotic administration in patients with suspected febrile neutropenia.[8] Therefore, we performed a retrospective cohort study to confirm the effect of nursing staff capacity on the compliance of nurses to empiric antibiotic treatment in patients with septic shock.