The crystals of enantiopure SS-[cis-Rh2（Ph2C6H4）2（O2CC2F4CO2）]2（（CH3）2CHCH2NH2）3（1） were obtained from the reaction of S-[cis-Rh2（Ph2C6H4）2（CH3CN）6]BF4（S-2） and（Et4N）2（O2CC2F4CO2） in CH2Cl2/CH3OH u...The crystals of enantiopure SS-[cis-Rh2（Ph2C6H4）2（O2CC2F4CO2）]2（（CH3）2CHCH2NH2）3（1） were obtained from the reaction of S-[cis-Rh2（Ph2C6H4）2（CH3CN）6]BF4（S-2） and（Et4N）2（O2CC2F4CO2） in CH2Cl2/CH3OH under the presence of sec-butyl amine.Compound 1 crystallizes in orthorhombic,space group P212121 with a = 16.880（5）,b = 28.728（9）,c = 20.475（6） ,V = 9929（5） 3,Z = 4,C95H96Cl5F8N3O8.50P4Rh4,Mr = 2280.52,Dc = 1.526 g/cm3,F（000） = 4608 and μ（MoKα） = 0.922 mm-1.The final R = 0.0488 and wR = 0.1164 for 17204 observed reflections with I 〉2σ（I） and R = 0.0814 and wR = 0.1374 for all data with absolute structure parameter =-0.04（3）.Compound 1 contains two inherently chiral S-[cis-Rh2（Ph2C6H4）2] moieties which are connected by two（O2CC2F4CO2） dicarboxylate ligands in the equatorial positions.One of the dirhodium units with Rh-Rh distance of 2.5445（8） is further coordinated by a sec-butyl amine in each axial position.Another dirohdium unit has only one axial sec-butyl amine ligand,and its Rh-Rh distance is 2.5079（9） .展开更多
A practical synthesis of stereoisomers of 3-aminocyclohexanecarboxylic acid and cis-3-aminocyclohexene-5- carboxylic acid was achieved from cyclohexene-4-carboxylic acid via a key resolving approach with chiral 1-phen...A practical synthesis of stereoisomers of 3-aminocyclohexanecarboxylic acid and cis-3-aminocyclohexene-5- carboxylic acid was achieved from cyclohexene-4-carboxylic acid via a key resolving approach with chiral 1-phenylethylamine.展开更多
A practical tactics in the classical resolutions was illustrated for affording the desired isomers in maximum yields. According to the practical tactics resolution of racemic ethyl nipecotate, Corey lactone and huperz...A practical tactics in the classical resolutions was illustrated for affording the desired isomers in maximum yields. According to the practical tactics resolution of racemic ethyl nipecotate, Corey lactone and huperzine A intermediate was successfully practiced. The basis of this practicability is the well-known Marckwald principle.展开更多
基金Financially supported by the National Natural Science Foundation of China (No. 20973173)
文摘The crystals of enantiopure SS-[cis-Rh2（Ph2C6H4）2（O2CC2F4CO2）]2（（CH3）2CHCH2NH2）3（1） were obtained from the reaction of S-[cis-Rh2（Ph2C6H4）2（CH3CN）6]BF4（S-2） and（Et4N）2（O2CC2F4CO2） in CH2Cl2/CH3OH under the presence of sec-butyl amine.Compound 1 crystallizes in orthorhombic,space group P212121 with a = 16.880（5）,b = 28.728（9）,c = 20.475（6） ,V = 9929（5） 3,Z = 4,C95H96Cl5F8N3O8.50P4Rh4,Mr = 2280.52,Dc = 1.526 g/cm3,F（000） = 4608 and μ（MoKα） = 0.922 mm-1.The final R = 0.0488 and wR = 0.1164 for 17204 observed reflections with I 〉2σ（I） and R = 0.0814 and wR = 0.1374 for all data with absolute structure parameter =-0.04（3）.Compound 1 contains two inherently chiral S-[cis-Rh2（Ph2C6H4）2] moieties which are connected by two（O2CC2F4CO2） dicarboxylate ligands in the equatorial positions.One of the dirhodium units with Rh-Rh distance of 2.5445（8） is further coordinated by a sec-butyl amine in each axial position.Another dirohdium unit has only one axial sec-butyl amine ligand,and its Rh-Rh distance is 2.5079（9） .
基金Project supported by the National Natural Science Foundation of China （Nos. 20172050, 20025205）.
文摘A practical synthesis of stereoisomers of 3-aminocyclohexanecarboxylic acid and cis-3-aminocyclohexene-5- carboxylic acid was achieved from cyclohexene-4-carboxylic acid via a key resolving approach with chiral 1-phenylethylamine.
文摘A practical tactics in the classical resolutions was illustrated for affording the desired isomers in maximum yields. According to the practical tactics resolution of racemic ethyl nipecotate, Corey lactone and huperzine A intermediate was successfully practiced. The basis of this practicability is the well-known Marckwald principle.
