Using one step solid-phase extraction for urine pretreatment and a new sample focusing mode-dynamic pH junction injection for increasing sensitivity, a simple and sensitive method for the analysis of urinary 8OHdG by ...Using one step solid-phase extraction for urine pretreatment and a new sample focusing mode-dynamic pH junction injection for increasing sensitivity, a simple and sensitive method for the analysis of urinary 8OHdG by capillary electrophoresis with end-column amprometric detection has been developed. The limit of detection was 20 nmol/L(signal to noise ratio S/N=3). The urinary concentration of 8OHdG in nine healthy persons and 28 cancer patients was determined. It was found that urinary concentration of 8OHdG in cancer patients was significantly higher than that in healthy persons[(35.26±27.96) nmol/L) vs. (13.51±5.08) nmol/L, P<0.05], the result demonstrated that 8OHdG may be a good biomarker for measurement of oxidative DNA damage in cancer patients. Furthermore, the excretion levels of urinary 8OHdG from cancer patients receiving surgical therapy are investigated, and the results demonstrated that the smoking has a strong effect on 8OHdG content.展开更多
配电网分支繁多,若要完全确定故障所在位置,不仅需要知道故障距离首端的距离,还要对故障的分支进行准确有效的判断。在基于线模行波突变的行波测距方法测得故障距离的基础上,根据零模入射行波在故障点处会同时产生零模和线模折反射波的...配电网分支繁多,若要完全确定故障所在位置,不仅需要知道故障距离首端的距离,还要对故障的分支进行准确有效的判断。在基于线模行波突变的行波测距方法测得故障距离的基础上,根据零模入射行波在故障点处会同时产生零模和线模折反射波的特点,提出了一种单端注入–多端检测的配电网故障分支判定方法。该方法利用线模行波到达首端的时间计算故障距离,并结合线模行波和零模行波到达主干线末端或二级分支末端的时间差协同判断故障所在分支。应用(power systems computer aided design,PSCAD)对不同分支的故障进行仿真实验,结果表明应用此方法判断故障分支的准确率较高。展开更多
文摘Using one step solid-phase extraction for urine pretreatment and a new sample focusing mode-dynamic pH junction injection for increasing sensitivity, a simple and sensitive method for the analysis of urinary 8OHdG by capillary electrophoresis with end-column amprometric detection has been developed. The limit of detection was 20 nmol/L(signal to noise ratio S/N=3). The urinary concentration of 8OHdG in nine healthy persons and 28 cancer patients was determined. It was found that urinary concentration of 8OHdG in cancer patients was significantly higher than that in healthy persons[(35.26±27.96) nmol/L) vs. (13.51±5.08) nmol/L, P<0.05], the result demonstrated that 8OHdG may be a good biomarker for measurement of oxidative DNA damage in cancer patients. Furthermore, the excretion levels of urinary 8OHdG from cancer patients receiving surgical therapy are investigated, and the results demonstrated that the smoking has a strong effect on 8OHdG content.
文摘配电网分支繁多,若要完全确定故障所在位置,不仅需要知道故障距离首端的距离,还要对故障的分支进行准确有效的判断。在基于线模行波突变的行波测距方法测得故障距离的基础上,根据零模入射行波在故障点处会同时产生零模和线模折反射波的特点,提出了一种单端注入–多端检测的配电网故障分支判定方法。该方法利用线模行波到达首端的时间计算故障距离,并结合线模行波和零模行波到达主干线末端或二级分支末端的时间差协同判断故障所在分支。应用(power systems computer aided design,PSCAD)对不同分支的故障进行仿真实验,结果表明应用此方法判断故障分支的准确率较高。