A novel method is developed for the determination of cefradine by using sodium nitroprusside as chromogenic reagent. The experiment indicates that a russety product is formed by the reaction of cefradine with sodium n...A novel method is developed for the determination of cefradine by using sodium nitroprusside as chromogenic reagent. The experiment indicates that a russety product is formed by the reaction of cefradine with sodium nitroprusside in basic solution, and the maximum absorption wavelength （λmax） of russety product is 505 rim. And the sensitization of tetradecyl benzyl dimethyl ammonium chloride for the reaction of cefradine with sodium nitroprusside is remarkable, The apparent molar absorption coefficient （5505） is 2.81 × 103 L/mol cm. The linear equation isA = 0.0657 ＋ 0.00804C （μg/mL） in the range of 1.50-55.0μg/mL of cefradine with a correlation coefficient r = 0.9992, and the detection limit is 1.38 p,g/mL. This method has been applied to determine cefradine in capsule and tablet samples.展开更多
This letter reports a novel method for preparing chromogenic calix[4]arenes, in which the 4-aminopyridine was diazotized with isoamyl nitrite in EtONa/EtOH, and mono(azo)-, bis(azo)- and tetra(azo)-substituted calix[4...This letter reports a novel method for preparing chromogenic calix[4]arenes, in which the 4-aminopyridine was diazotized with isoamyl nitrite in EtONa/EtOH, and mono(azo)-, bis(azo)- and tetra(azo)-substituted calix[4]arenes were obtained as main product respectively by diazo-coupling in different molar ratio to calix[4]arene in non-aqueous solution at 0-5 degrees.展开更多
Summary： The specimens of ductal carcinoma in situ （DCIS） with early invasion, and specimens col- lected by core needle biopsy （CNB） tend to contain limited amount of invasive component, so it is im- perative to ...Summary： The specimens of ductal carcinoma in situ （DCIS） with early invasion, and specimens col- lected by core needle biopsy （CNB） tend to contain limited amount of invasive component, so it is im- perative to explore a new technique which can assess HER2 gene status accurately for the limited inva- sive cancer component in these specimens. Dual staining technique of combining immunohistochemis- try （IHC） for myoepithelial cells and single or dual probe chromogenic in situ hybridization （CISH） for HER2 gene was performed on routinely processed paraffin sections from 20 cases diagnosed as having DCIS with invasive cancer. Among them, 10 had fluorescence in situ hybridization （FISH）-confirmed amplification of HER2 and 10 had FISH-confirmed non-amplification of HER2. We successfully de- tected HER2 genetic signals and myoepithelial IHC markers （SMM-HC or CK5/6） simultaneously on a single section in all 20 specimens. Myoepithelial markers and HER2 signals detected by dual staining assay were consistent with those by individual technique performed alone. HER2 gene amplification results determined by dual staining assay were 100% consistent with those of FISH. Dual staining tech- nique which allows simultaneous detection of myoepithelial marker protein and cancerous HER2 gene is feasible, and it has potential to be used in clinical practice for effective determination of HER2 ampli- fication in limited invasive component.展开更多
A diester-calix[4]crown-4-ether bearing mono (azophenol) moiety shows a larger spectral change toward Ca2+ than other alkali and alkaline eafth cations.
Chromogenic windows enable both energy-saving and daylighting regulation.However,the human response to the luminous environment affected by them is difficult to test,since their features of dynamic change and tinting ...Chromogenic windows enable both energy-saving and daylighting regulation.However,the human response to the luminous environment affected by them is difficult to test,since their features of dynamic change and tinting automatically.This study explores the research methods,including experimental design and statistical analysis,by literature review and an experiment demonstration.The results show that a proper size of the test room is significant to obtain desired data,and the advanced VR technologies have the potential to be applied for testing these dynamic variables.Bayesian approaches are recommended to be tried and get more accurate interference about the experimental results.展开更多
内蒙古白云鄂博矿床是世界最大的稀土矿之一,其矿床内部及周边出露有大量板岩并且板岩具多种颜色(黑色、黄绿色、深绿色等),板岩的研究程度相对较低。为了厘定板岩的矿物组成,本次研究应用玻片全扫描、TIMA(TESCAN Intergrated Mineral ...内蒙古白云鄂博矿床是世界最大的稀土矿之一,其矿床内部及周边出露有大量板岩并且板岩具多种颜色(黑色、黄绿色、深绿色等),板岩的研究程度相对较低。为了厘定板岩的矿物组成,本次研究应用玻片全扫描、TIMA(TESCAN Intergrated Mineral Analyzer)全扫描、电子探针、LA-ICP-MS(激光剥蚀电感耦合等离子体质谱仪)对其矿物组合特征和成分特征进行分析。玻片全扫描和TIMA全扫描比对表明板岩虽颜色各异,但主要由正长石组成,正长石体积比可达86.37%;在白云鄂博矿床范围内正长石有隐晶质、单晶集合体和单晶三种赋存形态。电子探针分析表明正长石中SiO_(2)为59.44%~64.76%、Al_(2)O_(3)为16.89%~19.73%、K_(2)O为13.96%~17.90%,K_(2)O/Na_(2)O为15.86~45.71;环带结构正长石K_(2)O的含量较其它正长石较低,K_(2)O/Na_(2)O为15.86~20.85。LA-ICP-MS分析表明正长石中Ba含量为700.08×10^(-6)~47 606.91×10^(-6),其它微量元素和稀土元素含量很少且差异不大。板岩整体颜色和正长石色带均具有随着Ba含量增多而颜色变深的现象,因此正长石的颜色深浅与Ba含量多少呈正相关关系。展开更多
文摘A novel method is developed for the determination of cefradine by using sodium nitroprusside as chromogenic reagent. The experiment indicates that a russety product is formed by the reaction of cefradine with sodium nitroprusside in basic solution, and the maximum absorption wavelength （λmax） of russety product is 505 rim. And the sensitization of tetradecyl benzyl dimethyl ammonium chloride for the reaction of cefradine with sodium nitroprusside is remarkable, The apparent molar absorption coefficient （5505） is 2.81 × 103 L/mol cm. The linear equation isA = 0.0657 ＋ 0.00804C （μg/mL） in the range of 1.50-55.0μg/mL of cefradine with a correlation coefficient r = 0.9992, and the detection limit is 1.38 p,g/mL. This method has been applied to determine cefradine in capsule and tablet samples.
文摘This letter reports a novel method for preparing chromogenic calix[4]arenes, in which the 4-aminopyridine was diazotized with isoamyl nitrite in EtONa/EtOH, and mono(azo)-, bis(azo)- and tetra(azo)-substituted calix[4]arenes were obtained as main product respectively by diazo-coupling in different molar ratio to calix[4]arene in non-aqueous solution at 0-5 degrees.
基金supported by grants from the Natural Science Foundation of Hubei Province (No. 2008CDB152)Science and Technology Foundation of Hubei Province (No.2007AA402A40)
文摘Summary： The specimens of ductal carcinoma in situ （DCIS） with early invasion, and specimens col- lected by core needle biopsy （CNB） tend to contain limited amount of invasive component, so it is im- perative to explore a new technique which can assess HER2 gene status accurately for the limited inva- sive cancer component in these specimens. Dual staining technique of combining immunohistochemis- try （IHC） for myoepithelial cells and single or dual probe chromogenic in situ hybridization （CISH） for HER2 gene was performed on routinely processed paraffin sections from 20 cases diagnosed as having DCIS with invasive cancer. Among them, 10 had fluorescence in situ hybridization （FISH）-confirmed amplification of HER2 and 10 had FISH-confirmed non-amplification of HER2. We successfully de- tected HER2 genetic signals and myoepithelial IHC markers （SMM-HC or CK5/6） simultaneously on a single section in all 20 specimens. Myoepithelial markers and HER2 signals detected by dual staining assay were consistent with those by individual technique performed alone. HER2 gene amplification results determined by dual staining assay were 100% consistent with those of FISH. Dual staining tech- nique which allows simultaneous detection of myoepithelial marker protein and cancerous HER2 gene is feasible, and it has potential to be used in clinical practice for effective determination of HER2 ampli- fication in limited invasive component.
文摘A diester-calix[4]crown-4-ether bearing mono (azophenol) moiety shows a larger spectral change toward Ca2+ than other alkali and alkaline eafth cations.
基金supported by the project funded by the China Postdoctoral Science Foundation project(2019M661617)the Faculty of Engineering at the University of Nottingham through a PhD studentship awarded to Runqi Liang.
文摘Chromogenic windows enable both energy-saving and daylighting regulation.However,the human response to the luminous environment affected by them is difficult to test,since their features of dynamic change and tinting automatically.This study explores the research methods,including experimental design and statistical analysis,by literature review and an experiment demonstration.The results show that a proper size of the test room is significant to obtain desired data,and the advanced VR technologies have the potential to be applied for testing these dynamic variables.Bayesian approaches are recommended to be tried and get more accurate interference about the experimental results.
文摘内蒙古白云鄂博矿床是世界最大的稀土矿之一,其矿床内部及周边出露有大量板岩并且板岩具多种颜色(黑色、黄绿色、深绿色等),板岩的研究程度相对较低。为了厘定板岩的矿物组成,本次研究应用玻片全扫描、TIMA(TESCAN Intergrated Mineral Analyzer)全扫描、电子探针、LA-ICP-MS(激光剥蚀电感耦合等离子体质谱仪)对其矿物组合特征和成分特征进行分析。玻片全扫描和TIMA全扫描比对表明板岩虽颜色各异,但主要由正长石组成,正长石体积比可达86.37%;在白云鄂博矿床范围内正长石有隐晶质、单晶集合体和单晶三种赋存形态。电子探针分析表明正长石中SiO_(2)为59.44%~64.76%、Al_(2)O_(3)为16.89%~19.73%、K_(2)O为13.96%~17.90%,K_(2)O/Na_(2)O为15.86~45.71;环带结构正长石K_(2)O的含量较其它正长石较低,K_(2)O/Na_(2)O为15.86~20.85。LA-ICP-MS分析表明正长石中Ba含量为700.08×10^(-6)~47 606.91×10^(-6),其它微量元素和稀土元素含量很少且差异不大。板岩整体颜色和正长石色带均具有随着Ba含量增多而颜色变深的现象,因此正长石的颜色深浅与Ba含量多少呈正相关关系。
