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Evaluation of the Quality of Micturition in Patients Who Underwent Anastomotic Urethroplasty at the Yaounde Central Hospital, Cameroon
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作者 Achille Aurele Mbassi Landry Oriole Mbouche +8 位作者 Junior Mekeme Mekeme Jean Crepin Eloundou Nkolo Bright Che Awondo Jean Cedrik Fouda Frantz Guy Epoupa Ngalle Cyril Kamadjou Pamela Anaba Laure Pierre Joseph Fouda Fru Forbuzshi III Angwafo 《Open Journal of Urology》 2024年第2期115-127,共13页
Introduction: Radiological investigation which is the gold standard to perform following anastomotic urethroplasty in order to evaluate the quality of micturition is costly. In our context, due to financial limitation... Introduction: Radiological investigation which is the gold standard to perform following anastomotic urethroplasty in order to evaluate the quality of micturition is costly. In our context, due to financial limitations, reconstructive urologists prefer to use the uroflowmetry in order to assess the micturition post-surgery. Therefore, the objective of the study was to assess the quality of micturition using the uroflowmetry after anastomotic urethroplasty. Methodology: We conducted an 11-year retrospective review (1<sup>st</sup> January 2006-31<sup>st</sup> December 2017) and a cross-sectional descriptive observational study for a period of 8 months (November 2017-June 2018) at the Urology and Andrology Department of the Yaounde Central Hospital (YCH) of patients who were diagnosed with urethral stenosis and underwent an anastomotic urethroplasty at the YCH. We excluded patients who had incomplete files, patients lost to follow-up and did not do pre-operative uroflowmetry. Quality of micturition was evaluated using a uroflowmetry. Data was analyzed using EPI info 7.0. Parametric variables were reported as means and standard deviations and percentages and counts were used to report categorical variables. Results: We had a sample of 60 patients. The mean age was 42 ± 5 years with extremes ranging from 20 to 76 years. Twenty-seven (27) patients, or 45%, had no post-operative complications, and those who did had a urinary tract infection (26.70%). In our series, we had 82% excellent results (patient satisfied with his urination with bell-shaped urinary stream and urinary flow greater than or equal to 15 ml/sec);15% good results (patient with moderate dysuria with average urinary stream and urinary flow between 10 and 14.9 ml/sec) and 3% poor results (severe dysuria with urinary flow less than 10 ml/sec, urinary retention or urinary incontinence). Based on these results we can say that the success rate in our series was 97%. 96.70% of patients were satisfied against 3.3% who were not. Conclusion: Anastomotic urethroplasty is the gold standard for the treatment of short urethral strictures. The results are good in the immediate and long term post-operative period. The use of the uroflowmetry as a screening tool for evaluating the quality of micturition after urethroplasty is effective. 展开更多
关键词 URETHRA STRICTURE anastomotic urethroplasty
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Men Urethra Strictures: Findings in Urethroplasties Care at the Andrology and Urology Department of Grand Yoff General Hospital in Dakar 被引量:1
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作者 B. Kouame M. Ndoye +5 位作者 F. Kramo M. Roua J. J. Gandonou S. Yassin L. Niang S. M. Gueye 《Open Journal of Urology》 2017年第10期173-185,共13页
Objectives: To report the experiment conducted at the HOGGY Urology department in the management of urethral stricture by urethroplasty, and to determine the factors that influence the results. Material and Method: We... Objectives: To report the experiment conducted at the HOGGY Urology department in the management of urethral stricture by urethroplasty, and to determine the factors that influence the results. Material and Method: We conducted a descriptive and analytical retrospective study based on the records of patients who underwent urethroplasty in the department, between February 2001 and September 2013. Results: Ninety-one (91) patients were enrolled. Urethroplasties prevalence was 0.83% of the surgical activity of the service. The mean age of patients was 39.83 years. Dysuria (30.77%) followed by pelvic trauma (28.57%) and urinary retentions (25.27%) was the main discovery mode. A periurethral coating was found in 32 patients. The infectious etiology accounted for 44% of cases. In 63% of cases, diagnostic was made by retrograde cystography. The penile urethra was the favorite seat of the UR in 70% of cases. The average length of the urethral stricture (US) was less than 1 cm in 41.17% of cases. The US was unique in more than half of the cases (58.33%). Anastomotic urethroplasty was the best surgical technique with 73.63% of patients. Postoperative morbidity involved 47 patients and was dominated by urinary infections (36 year old). The average duration of follow-up of operated patients was 29 months. After 6 months of follow-up, the best results were obtained with the termino-terminal urethroplasty technique with 62.5%. After a follow-up of 4 years, the success rate was 58.24%. The length of the stenosis and the allocation of gestures on the urethra were the two factors of failure. Conclusion: Stenosis is common in our regions. Treatment results are disappointing. Urethroplasty is the gold standard of surgical treatment and anastomotic urethroplasty gives better results. 展开更多
关键词 URETHRAL STRICTURE urethroplasty anastomotic urethroplasty
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Preliminary clinical study on non-transecting anastomotic bulbomembranous urethroplasty 被引量:1
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作者 Wei Le Chao Li +2 位作者 Jinfu Zhang Denglong Wu Bo Liu 《Frontiers of Medicine》 SCIE CAS CSCD 2017年第2期277-283,共7页
This study aims to investigate the effect of non-transecting anastomotic urethroplasty for treatment of posterior urethral stricture. A total of 23 patients with traumatic posterior urethral stricture were enrolled an... This study aims to investigate the effect of non-transecting anastomotic urethroplasty for treatment of posterior urethral stricture. A total of 23 patients with traumatic posterior urethral stricture were enrolled and then divided into two groups. In one group, 12 patients underwent non-transecting anastomotic urethroplasty. In the other group, 11 patients underwent conventional posterior urethra end-to-end anastomosis. The effect of operation was evaluated using the following parameters: the bleeding amount during operation, operation time, IIEF-5 scores after operation, maximum flow rate (Qmax), and rating scale of quality of life (QoL). The comparison between the conventional posterior urethra end-to-end anastomosis group and the non-transecting anastomotic urethroplasty group showed no significant difference with regard to average operation time. However, a significant difference was observed between the groups with regard to the bleeding amount during operation. The patients in the group of uon-transecting anastomotic urethroplasty urinated smoothly after the removal of catheter. Meanwhile, one patient from the group of conventional posterior urethra end-to-end anastomosis had difficulty urinating after the removal of catheter. Furthermore, significant differences in the operation time, bleeding amount during operation, IIEF-5 scores after operation, and rating scale of QoL were observed, whereas no significant difference was observed between urine flow rates of the two groups after operation. Overall, non-transecting anastomotic urethroplasty is effective for posterior urethra reconstruction, and it can reduce the occurrence rate of erectile dysfunction after operation. 展开更多
关键词 anastomotic urethroplasty transecting posterior urethra reconstruction
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Male Urethral Stricture: Epidemiological, Clinical, and Therapeutic Aspects in Kara
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作者 Komi Hola Sikpa Gnimdou Botcho +7 位作者 Edoe Viyome Sewa Sabi Rachid Sade Essomindedou Leloua Messan Semefa Agbedey Essodina Padja Kossiwa Rose Assou Kodjo Tengue Tchilabalo Matchonna Kpatcha 《Open Journal of Urology》 2023年第4期101-107,共7页
Background: Urethral stricture is a pathology frequently encountered in urological practice. Management is often surgical, with possible recurrences. What about this pathology in Kara, a semi-urban city? Objective: As... Background: Urethral stricture is a pathology frequently encountered in urological practice. Management is often surgical, with possible recurrences. What about this pathology in Kara, a semi-urban city? Objective: Assess the management of male urethral stricture in Kara. Patients and Methods: This was a descriptive study with retrospective data collection. The study took place in the urology department of the teaching hospital of Kara, from December 2020 to December 2022. All cases of male urethral stricture, surgically treated at the teaching hospital of Kara, were listed. The inclusion criteria were as follows: any patient who had been treated surgically for male urethral stricture in the urology department of the teaching Hospital of Kara. The operating theater register and hospital records were used to collect the data. The diagnosis of urethral stricture had been made with retrograde urethrogram. A total of 24 patients were treated for male urethral stricture during the study period. The following variables were studied: age, reason for consultation, location, length, and etiology of the stricture;the type of treatment received: optical internal urethrotomy, or anastomotic urethroplasty, and the results. The result was considered good if, after removal of the urethral catheter, the patient regained his micturition without the need for dilatation;the result was considered average if, after removal of the urethral catheter, the patient needed one or more dilatation sessions to regain urination;the result was considered poor if, after removal of the catheter, the patient did not regain good micturition despite the urethral dilatation sessions. Microsoft excel and epi info 7 software were used for data processing. Results: The average age of our patients was 43.7 years ± 10.18 with extremes ranging from 27 to 70 years. The most represented age groups were that of 40 to 50 years, with 37.5% of cases;and that of 30 to 40 years with 33.3% of cases. The patients had consulted for urine retention in 66.6% of cases;the location of urethral stricture was bulbar in 45.8% of cases. The most found etiology was infectious in 58.3% of cases. Among our patients, 58.3% had received optical internal urethrotomy as treatment, while 41.6% of our patients had received anastomotic urethroplasty as treatment. Postoperatively, after removal of the urinary catheter, 87.5% of patients had benefited from one or repeated dilatation. In terms of results, we had a good result in 20.8% of patients;the result was average in 45.8% of patients, and poor in 33.3% of patients. The average duration of follow-up was 14.3 +/- 7.2 months (3-27). Conclusion: Male urethral stricture mainly affects young adults in Kara. Surgical management is done by optical internal urethrotomy and/or anastomotic urethroplasty. 展开更多
关键词 Male Urethral Stricture Optical Internal Urethrotomy anastomotic urethroplasty Kara TOGO
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沟槽负压引流对经会阴尿道吻合术患者短期预后的影响
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作者 刘振华 黄广林 李贵忠 《现代泌尿外科杂志》 CAS 2023年第8期683-686,共4页
目的 探讨沟槽负压引流对经会阴尿道吻合术患者短期预后的影响。方法 回顾性分析2021年5月-2022年4月在北京积水潭医院行经会阴尿道吻合术患者78例的临床资料,根据术后留置伤口引流方式分为沟槽负压引流管组(试验组,n=42)和传统橡皮引... 目的 探讨沟槽负压引流对经会阴尿道吻合术患者短期预后的影响。方法 回顾性分析2021年5月-2022年4月在北京积水潭医院行经会阴尿道吻合术患者78例的临床资料,根据术后留置伤口引流方式分为沟槽负压引流管组(试验组,n=42)和传统橡皮引流条组(对照组,n=36),比较两组患者手术资料、术后伤口引流量、阴囊水肿率、切口感染率、切口疼痛视觉模拟评分(VAS)以及最大尿流率的差异。结果 试验组的手术切口长度比对照组长[(12.9±1.6) cm vs.(12.1±1.5) cm,P=0.041)],术后3 d的总引流量比对照组明显增加[(66.1±51.9) mL vs.(36.0±16.9) mL,P=0.001)],阴囊水肿率(21.4%vs.47.2%,P=0.016)和VAS(3.2±1.0 vs.3.9±1.1,P=0.008)比对照组明显降低,而伤口感染率、最大尿流率与对照组相比差异无统计学意义(P>0.05)。结论 沟槽负压引流能够充分引流会阴部切口组织积液,减少术后伤口并发症,更有利于经会阴尿道吻合术患者的术后快速恢复。 展开更多
关键词 沟槽负压引流 橡皮条引流 尿道狭窄 经会阴尿道吻合术 术后 预后
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尿道狭窄3种术式手术前后勃起功能状态的临床研究 被引量:5
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作者 冼志勇 陈庆科 +7 位作者 陈汉忠 叶楚津 冯自卫 李东 蒲小勇 王怀鹏 毛向明 刘久敏 《中华男科学杂志》 CAS CSCD 2014年第8期706-708,共3页
目的:对3种术式治疗尿道狭窄患者手术前后勃起功能状态进行研究。方法:分别采用3种术式对126例尿道狭窄男性患者进行治疗。35例患者接受尿道狭窄部位阴茎皮瓣重建术,52例患者接受尿道端端吻合术,39例患者接受内窥镜下尿道内切开术。通... 目的:对3种术式治疗尿道狭窄患者手术前后勃起功能状态进行研究。方法:分别采用3种术式对126例尿道狭窄男性患者进行治疗。35例患者接受尿道狭窄部位阴茎皮瓣重建术,52例患者接受尿道端端吻合术,39例患者接受内窥镜下尿道内切开术。通过电话随访、面访方式,采用国际勃起功能指数问卷(IIEF-5)评分对每组患者术前、术后勃起功能的总体情况进行评价,同时利用夜间阴茎胀大实验(NPT)对患者进行诊断。结果:行尿道狭窄部位阴茎皮瓣重建术组IIEF-5评分术前与术后分别为(17.1±2.6)分和(13.5±4.5)分;行尿道端端吻合术组IIEF-5评分术前与术后分别为(17.1±3.0)分和(11.1±4.8)分;行尿道内切开术组IIEF-5评分术前与术后分别为(17.6±2.2)分和(14.5±4.4)分。与术前相比,3组患者术后IIEF-5评分均显著下降,其差异具有统计学意义(P<0.05)。上述3种术式术后勃起功能障碍发生率分别为8.57%(3/35)、26.92%(14/52)、10.26%(4/39),尿道端端吻合术显著高于其他2种术式(P均<0.05)。结论:3种术式治疗尿道狭窄术后IIEF-5评分均有所下降,与尿道端端吻合术相比,尿道狭窄部位阴茎皮瓣重建术与尿道内切开术术后勃起功能障碍的发生率较低,应注重对适宜术式的选择以确保对患者性功能的有效保护。 展开更多
关键词 尿道狭窄 尿道狭窄部位阴茎皮瓣重建术 尿道端端吻合术 尿道内切开术 勃起功能障碍
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耻骨会阴联合切口后尿道吻合术治疗复杂男性骨盆骨折后尿道离断 被引量:4
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作者 王建伟 满立波 +6 位作者 徐啸 刘振华 何峰 黄广林 翟建坡 周宁 李玮 《北京大学学报(医学版)》 CAS CSCD 北大核心 2020年第4期646-650,共5页
目的:总结耻骨会阴联合切口耻骨整块切除后尿道吻合治疗复杂男性骨盆骨折后尿道离断(pelvic fracture urethral distraction defect,PFUDD)的临床效果及体会。方法:回顾性分析2010年1月至2019年12月采用耻骨会阴联合切口后尿道吻合术治... 目的:总结耻骨会阴联合切口耻骨整块切除后尿道吻合治疗复杂男性骨盆骨折后尿道离断(pelvic fracture urethral distraction defect,PFUDD)的临床效果及体会。方法:回顾性分析2010年1月至2019年12月采用耻骨会阴联合切口后尿道吻合术治疗的复杂PFUDD患者17例,其中合并尿道直肠瘘2例(11.8%)、尿道会阴皮肤瘘1例(5.9%)。既往经会阴后尿道吻合失败6例(35.3%),其中2例(11.8%)为2次开放手术失败;尿道扩张治疗3例(17.6%);内切开治疗1例(5.9%)。所有患者均采用经耻骨会阴联合切口整块切除耻骨再行后吻合尿道。结果:本组患者平均年龄35.5(21~62)岁,尿道狭窄的长度平均5.5(4.5~7.0)cm,手术时间平均190(150~260)min,平均术中估计失血460(200~1200)mL。术后局部伤口感染4例(23.5%),下肢静脉血栓1例,患者平均随访27(7~110)个月。术后平均尿流率22.7(15.5~40.7)mL/s,合并尿道直肠瘘、尿道会阴瘘等均治愈。1例患者拔管后2周出现尿线变细及尿频、尿急等泌尿系感染症状,行膀胱镜检查示吻合口处狭窄,给予内切开并留置尿管2周,术后随访排尿通畅。本组17例患者手术成功率为94.1%(16/17)。结论:耻骨会阴联合切口后尿道吻合术治疗复杂男性PFUDD效果明确,成功率为94.1%。此类手术损伤大、耗时长、术后并发症高,适合在区域性尿道修复重建中心开展。 展开更多
关键词 后尿道吻合成形术 骨盆骨折后尿道离断 耻骨切除
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经会阴三步法手术策略治疗单纯性男性骨盆骨折后尿道离断 被引量:5
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作者 王建伟 满立波 +5 位作者 黄广林 王海 徐啸 朱晓斐 李玮 刘振华 《北京大学学报(医学版)》 CAS CSCD 北大核心 2018年第4期617-620,共4页
目的:总结经会阴三步法手术策略治疗男性单纯性骨盆骨折后尿道离断(pelvic fracture urethral distraction defect,PFUDD)的临床效果及体会。方法:回顾性分析2014年1月至2015年10月收治的男性单纯性PFUDD患者162例,均无会阴瘘和直肠瘘... 目的:总结经会阴三步法手术策略治疗男性单纯性骨盆骨折后尿道离断(pelvic fracture urethral distraction defect,PFUDD)的临床效果及体会。方法:回顾性分析2014年1月至2015年10月收治的男性单纯性PFUDD患者162例,均无会阴瘘和直肠瘘等并发症,为单纯性PFUDD。既往行经会阴尿道吻合术30例(18.5%),尿道会师术17例(10.5%),尿道内切开17例(10.5%),余均为伤后急诊行膀胱造瘘,未行其他处理措施。按照经会阴三步法策略行后尿道吻合成形:第一步,游离尿道海绵体球部并切除瘢痕,行远近端尿道吻合成形;如果远近端尿道无法吻合或吻合口张力较大,则依次行以下第二步和第三步;第二步,向远端适当游离尿道海绵体,劈开尿道海绵体纵膈以缩短吻合口远近端距离;第三步,耻骨部分或整块切除,进一步缩短吻合口距离并充分暴露近端尿道。结果:本组患者年龄平均36.3(16~74)岁,创伤性尿道损伤病史平均13.5(3~124)个月,患者尿道狭窄长度平均2.7(0.5~6.5)cm,手术时间平均92(45~240)min,术中平均估计失血量120(60~800)m L,术后或术中输血3例(1.9%)。162例患者采用经会阴三步法手术策略均达到无张力吻合(162/162,100%),其中第一步完成吻合50例(30.9%);第一步结合第二步完成74例(45.7%);使用三个步骤完成38例(23.5%),其中耻骨整块切除4例(2.5%)。患者平均随访19.5(11~45)个月,18例患者术后狭窄复发,手术成功率为88.9%(144/162)。结论:采用经会阴三步法手术策略治疗男性单纯创伤性后尿道狭窄效果明确,均能够达到无张力吻合效果,手术成功率为88.9%。 展开更多
关键词 后尿道吻合成形术 骨盆骨折后尿道离断 后尿道狭窄
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耻骨下缘部分切除辅助后尿道吻合术在男性骨盆骨折后尿道离断修复中的应用 被引量:4
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作者 王建伟 徐啸 +4 位作者 鲍正清 刘振华 何峰 黄广林 满立波 《北京大学学报(医学版)》 CAS CSCD 北大核心 2021年第4期798-802,共5页
目的:总结耻骨下缘部分切除技术辅助后尿道吻合术治疗男性骨盆骨折后尿道离断(pelvic fracture urethral distraction defect,PFUDD)的临床效果并分析其技术要点。方法:回顾性分析采用耻骨下缘部分切除技术辅助后尿道吻合术治疗的男性PF... 目的:总结耻骨下缘部分切除技术辅助后尿道吻合术治疗男性骨盆骨折后尿道离断(pelvic fracture urethral distraction defect,PFUDD)的临床效果并分析其技术要点。方法:回顾性分析采用耻骨下缘部分切除技术辅助后尿道吻合术治疗的男性PFUDD患者63例,患者均以以下步骤完成后尿道吻合:(1)充分游离尿道海绵体球部,在尿道闭锁处切断尿道并切除瘢痕;(2)向远端适当游离尿道海绵体,劈开阴茎海绵体纵隔;(3)切除耻骨联合下缘,完成无张力吻合。结果:63例患者的平均年龄(39.2±15.6)岁(15~72岁),平均尿道狭窄长度(3.85±0.91)cm(1.5~5.5 cm),均采用耻骨下缘切除技术辅助完成后尿道吻合,手术时间平均为(160.2±28.1)min(110~210 min),术中估计失血量为(261.1±130.3)mL(100~800 mL),术后或术中输血者3例(4.8%)。术后并发症包括出血和泌尿系感染,均对症处理后治愈。患者的中位随访时间为23个月(12~37个月),术后平均最大尿流率为(23.7±7.4)mL/s(15.0~48.2 mL/s)。耻骨下缘切除技术辅助后尿道吻合治疗男性PFUDD的手术成功率为95.2%(60/63例)。结论:耻骨下缘部分切除能够有效缩短远近端尿道间距离,辅助部分复杂PFUDD患者完成无张力吻合,技术要点包括阴茎海绵体纵隔切开充分暴露耻骨联合、游离结扎阴茎背静脉、充分切除耻骨骨质下方与尿道之间瘢痕组织暴露健康尿道近端。 展开更多
关键词 耻骨部分切除 后尿道吻合成形术 骨盆骨折后尿道离断 尿道狭窄
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尿道造影片中膀胱上浮线在后尿道端端吻合术中的初步应用 被引量:1
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作者 彭光伟 余青松 +5 位作者 李超 周伟东 徐成党 吴登龙 王海峰 张军 《现代泌尿外科杂志》 CAS 2019年第4期284-286,共3页
目的探讨尿道造影片中膀胱上浮线(BF,也即股骨头上缘水平线)在后尿道端端吻合术治疗骨盆骨折引起的后尿道狭窄(闭锁)中临床应用和价值。方法本研究共42例骨盆骨折引起的后尿道狭窄(闭锁)患者,术前尿道造影片中,通过BF线来判断是否存在... 目的探讨尿道造影片中膀胱上浮线(BF,也即股骨头上缘水平线)在后尿道端端吻合术治疗骨盆骨折引起的后尿道狭窄(闭锁)中临床应用和价值。方法本研究共42例骨盆骨折引起的后尿道狭窄(闭锁)患者,术前尿道造影片中,通过BF线来判断是否存在膀胱上浮,将患者分为膀胱上浮组(18例)和膀胱未上浮组(24例);分析比较两组患者的手术时间、术中出血量、术中是否行耻骨下缘切除、术后尿流率等的差异。结果膀胱上浮组手术时间、术中出血量明显高于膀胱未上浮组(P<0.05);膀胱上浮组术中行耻骨下缘切除16例(88.89%),膀胱未上浮组术中行耻骨下缘切除5例(20.83%);术后尿流率两组间未见无明显差异(P>0.05)。结论尿道造影片中BF线对于术前预判后尿道端端吻合术手术难度有一定指导和临床意义。 展开更多
关键词 尿道狭窄 尿道闭锁 尿道重建 膀胱上浮 尿道端端吻合
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尿道吻合术后留置尿管时间与远期效果的相关性观察
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作者 梁志强 徐托 +2 位作者 张尚文 冯树开 洪家文 《国际医药卫生导报》 2012年第1期53-55,共3页
目的分析探讨尿道吻合术后留置尿管时间与远期效果的相关性。方法将19例患者随机分两组,均急诊一期行尿道吻合术,在不同时间段拔除尿管后观察吻合段尿道狭窄情况并进行临床效果对比。结果A组9例术后4周拔尿管,常规定期尿道扩张,随访... 目的分析探讨尿道吻合术后留置尿管时间与远期效果的相关性。方法将19例患者随机分两组,均急诊一期行尿道吻合术,在不同时间段拔除尿管后观察吻合段尿道狭窄情况并进行临床效果对比。结果A组9例术后4周拔尿管,常规定期尿道扩张,随访6~12个月。A组中7例(77.8%)无吻合段尿道继发狭窄,最大尿流率15.3。31.1ml/s,平均22.1ml/s;术后常规3个月每月1次膀胱镜检,均顺利通过F21膀胱镜;A组中2例(22.2%)吻合段尿管继发狭窄,需再行吻合段尿道疤痕切除吻合术。B组10例术后12周拔除尿管,最大尿流率19.2。38.5ml/s,平均24.3ml/s,本组均未作尿道扩张;术后常规3个月每月1次膀胱镜检查,均能顺利通过F21膀胱镜,随访6~12个月,吻合段尿道无继发狭窄。结论尿道吻合术后,3个月内尿道留置尿管时间与吻合段尿道狭窄发生率呈负相关。 展开更多
关键词 尿道损伤 尿道吻合 尿道狭窄 尿道瘢痕 尿管
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尿道端端吻合术后狭窄复发的危险因素分析 被引量:6
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作者 杨涛 谢弘 +4 位作者 傅强 撒应龙 张炯 宋鲁杰 金重睿 《中华泌尿外科杂志》 CAS CSCD 北大核心 2020年第1期32-36,共5页
目的分析尿道狭窄患者行尿道端端吻合术(excision and primary anastomotic urethroplasty,EPA)后狭窄复发的危险因素。方法回顾性分析2017年1月至2018年12月上海交通大学附属第六人民医院收治的209例尿道狭窄患者的临床资料。年龄42.1(... 目的分析尿道狭窄患者行尿道端端吻合术(excision and primary anastomotic urethroplasty,EPA)后狭窄复发的危险因素。方法回顾性分析2017年1月至2018年12月上海交通大学附属第六人民医院收治的209例尿道狭窄患者的临床资料。年龄42.1(5~78)岁。肥胖(体质指数>28 kg/m2)25例(12.0%)。既往有糖尿病史12例(5.7%),术前3个月吸烟史103例(49.3%)。术前未行尿道扩张127例(60.8%),尿道扩张1~2次42例(20.1%),尿道扩张≥3次40例(19.1%)。术前有尿道内切开术史56例(26.8%)。术前无尿道成形术史157例(75.1%),尿道成形术1次38例(18.2%),尿道成形术≥2次14例(6.7%)。术前行膀胱造瘘201例(96.2%),未行膀胱造瘘8例(3.8%)。后尿道狭窄183例,球部尿道狭窄26例。狭窄时间35.1(1~360)个月。狭窄段长度(3.19±0.65)cm。病因为外伤190例,医源性损伤12例,炎性狭窄2例,其他5例。患者均行EPA治疗,69例(33.0%)术中行耻骨下缘切除。术后复发标准:拔除导尿管后出现排尿困难,经尿道镜或尿道造影检查提示手术部位尿道狭窄。对可能导致狭窄复发的因素采用Cox比例风险回归模型进行单因素和多因素分析。结果本组209例术后随访18.8(3~32)个月。31例(14.8%)出现狭窄复发,复发时间(5.3±5.6)个月。单因素分析结果显示,狭窄时间(HR=1.007,P<0.001),狭窄段长度(HR=5.334,P<0.001),尿道内切开术史(HR=2.901,P=0.003),尿道扩张≥3次(HR=6.214,P<0.001),尿道成形术1次、≥2次(HR=4.175,P=0.001、HR=9.885,P<0.001),术前3个月吸烟史(HR=2.605,P=0.016),膀胱造瘘(HR=0.231,P=0.006),耻骨下缘切除(HR=6.603,P<0.001)与狭窄复发有相关性。多因素分析结果显示狭窄段长度(HR=4.911,P<0.001),尿道成形术1次、≥2次(HR=2.387,P=0.045、HR=3.688,P=0.015),术前3个月吸烟史(HR=2.730,P=0.030)是狭窄复发的独立危险因素。结论EPA术后尿道狭窄复发多集中在术后6个月内,患者尿道狭段窄长度、尿道成形术史、术前3个月吸烟史是狭窄复发的独立危险因素。 展开更多
关键词 尿道狭窄 尿道端端吻合术 狭窄复发 危险因素
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尿道端端吻合术对外伤性尿道狭窄患者勃起功能影响的临床研究 被引量:8
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作者 唐晨野 傅强 《临床泌尿外科杂志》 北大核心 2011年第8期579-583,共5页
目的:研究尿道端端吻合术对外伤性尿道狭窄患者勃起功能的影响。方法:对41例采用尿道端端吻合术治疗的骨盆骨折导致尿道损伤(PFUDD)相关尿道狭窄患者手术前后两个阶段进行血管活性药物注射后阴茎血流彩色多普勒超声波(PPUD)检查和国际... 目的:研究尿道端端吻合术对外伤性尿道狭窄患者勃起功能的影响。方法:对41例采用尿道端端吻合术治疗的骨盆骨折导致尿道损伤(PFUDD)相关尿道狭窄患者手术前后两个阶段进行血管活性药物注射后阴茎血流彩色多普勒超声波(PPUD)检查和国际勃起功能指数-5(11EF-5)间卷调查,并对数据进行统计学分析。结果:所有41例患者手术前后的IIEF-5评分无显著差异,且勃起功能无明显变化者占大多数,约为56%。各年龄组、狭窄长度组及狭窄部位组患者手术前后的IIEF-5评分均无显著差异,但术后勃起功能提高组、不变组和降低组3组间的狭窄长度差异有统计学意义(2.16±1.49 vs 2.28±0.88 vs 3.50±1.53,P=0.0134),且差异主要存在于降低组与提高组或不变组之间(P=0.0129,0.0165)。轻度及中低度ED组患者术后IIEF-5评分出现明显下降(13.86±1.88 vs 11.43±3.37,P=0.0202),而中度及重度ED组患者则无明显变化。非血管性ED组患者手术前后的IIEF-5评分差异有统计学意义(14.88±1.81 vs 10.88±4.02,P=0.0103),动脉性和静脉性ED组患者手术前后评分则无明显差别。结论:尿道端端吻合术对PFIDD等外伤相关尿道狭窄患者的勃起功能没有显著影响,患者术后勃起功能的变化情况与狭窄长度、术前性功能状态等有关,而与患者年龄、狭窄部位等没有明确的关系。 展开更多
关键词 尿道端端吻合术.夕h伤性尿道狭窄 勃起功能
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尿道成形术治疗男性尿道狭窄的技术变迁 被引量:2
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作者 修贤杰 宋鲁杰 《中华外科杂志》 CAS CSCD 北大核心 2022年第11期981-986,共6页
尿道成形术是治疗男性尿道狭窄的重要手段。目前尿道成形术主要分为吻合成形术和替代成形术两大类,其中吻合成形术主要包括端端吻合和非离断吻合,替代成形术主要包括带蒂皮瓣成形术和游离黏膜成形术。吻合成形术在短段球部尿道狭窄与骨... 尿道成形术是治疗男性尿道狭窄的重要手段。目前尿道成形术主要分为吻合成形术和替代成形术两大类,其中吻合成形术主要包括端端吻合和非离断吻合,替代成形术主要包括带蒂皮瓣成形术和游离黏膜成形术。吻合成形术在短段球部尿道狭窄与骨盆骨折后尿道狭窄中显示出良好效果,其中非离断吻合成为医源性、单发、短段、非闭锁性狭窄的新术式。在移植物尿道成形术方面,目前一期手术使用最为广泛,但仍有许多复杂尿道狭窄病例必须通过分期手术解决。在替代材料的选择上,阴茎皮瓣与口腔黏膜目前应用较为广泛。如何个性化选择最优的术式和替代材料将是未来值得关注的问题。积累更多的长期随访资料,有助于客观比较各种术式和移植物的治疗效果。 展开更多
关键词 尿道狭窄 泌尿外科手术 尿道吻合成形术 尿道替代成形术 前尿道狭窄 后尿道狭窄
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狭窄段切除补片尿道扩大成形术在治疗尿道球部狭窄中的应用 被引量:1
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作者 华晓亮 徐玉节 李兵 《临床泌尿外科杂志》 2018年第3期177-181,共5页
目的:综述狭窄段切除补片尿道扩大成形术在尿道重建中的应用,评估其手术效果及并发症的发生率。方法:利用PubMed/Medline检索有关狭窄段切除补片尿道扩大成形术治疗尿道球部狭窄的临床研究文章,提取数据,对其进行总结分析。同时对资料... 目的:综述狭窄段切除补片尿道扩大成形术在尿道重建中的应用,评估其手术效果及并发症的发生率。方法:利用PubMed/Medline检索有关狭窄段切除补片尿道扩大成形术治疗尿道球部狭窄的临床研究文章,提取数据,对其进行总结分析。同时对资料结果中行腹侧补片和背侧补片替代尿道的成功率进行χ~2检验,采用SPSS 19.0进行统计分析。结果:共纳入11篇文章,共有597例患者进行了狭窄段切除补片尿道扩大成形术,总体成功率达91.3%,其中行腹侧补片替代尿道的总体成功率91.3%,行背侧补片替代尿道的总体成功率92.1%,二者差异无统计学意义(χ~2=0.097,P=0.756)。术后并发症以勃起功能障碍和尿外渗最为多见,勃起功能障碍总体发生率为4.9%,尿外渗的总体发生率为4.5%,未见术后阴茎下弯的报道。结论:狭窄段切除补片尿道扩大成形术手术成功率高,术后并发症小,是治疗尿道球部狭窄的有效手术方式,同时腹侧补片与背侧补片相比较,二者在手术成功率上差异无统计学意义。 展开更多
关键词 狭窄段切除补片尿道扩大成形术 尿道成形术 尿道狭窄
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