Therapeutic flexible endoscopic robotic systems have been developed primarily as a platform for endoscopic submucosal dissection(ESD)in the treatment of earlystage gastrointestinal cancer.Since ESD can only be perform...Therapeutic flexible endoscopic robotic systems have been developed primarily as a platform for endoscopic submucosal dissection(ESD)in the treatment of earlystage gastrointestinal cancer.Since ESD can only be performed by highly skilled endoscopists,the goal is to lower the technical hurdles to ESD by introducing a robot.In some cases,such robots have already been used clinically,but they are still in the research and development stage.This paper outlined the current status of development,including a system by the author’s group,and discussed future challenges.展开更多
The development of strain sensors with both superior sensitivity(gauge factor(GF)>100)and broad strain-sensing range(>50%strain)is still a grand challenge.Materials,which demonstrate significant structural defor...The development of strain sensors with both superior sensitivity(gauge factor(GF)>100)and broad strain-sensing range(>50%strain)is still a grand challenge.Materials,which demonstrate significant structural deformation under microscale motion,are required to offer high sensitivity.Structural connection of materials upon large-scale motion is demanded to widen strainsensing range.However,it is hard to achieve both features simultaneously.Herein,we design a crepe roll structure-inspired textile yarn-based strain sensor with one-dimensional(1D)-two-dimensional(2D)nanohybrid strain-sensing sheath,which possesses superior stretchability.This ultrastretchable strain sensor exhibits a wide and stable strain-sensing range from microscale to large-scale(0.01%–125%),and superior sensitivity(GF of 139.6 and 198.8 at 0.01%and 125%,respectively)simultaneously.The strain sensor is structurally constructed by a superelastic 1D-structured core elastomer polyurethane yarn(PUY),a novel high conductive crepe roll-structured(CRS)1D-2D nanohybrid multilayer sheath which assembled by 1D nanomaterials silver nanowires(AgNWs)working as bridges to connect adjacent layers and 2D nanomaterials graphene nanoplates(GNPs)offering brittle lamellar structure,and a thin polydopamine(PDA)wrapping layer providing protection in exterior environment.During the stretching/deformation process,microcracks originate and propagate in the GNPs lamellar structure enable resistance to change significantly,while AgNWs bridge adjacent GNPs to accommodate applied stress partially and boost strain.The 1D crepe roll structure-inspired strain sensor demonstrates multifunctionality in multiscale deformative motion detection,such as respiratory motions of Sprague–Dawleyw rat,flexible digital display,and proprioception of multi-joint finger bending and antagonistic flexion/extension motions of its flexible continuum body.展开更多
基金Supported by Grant-in-Aid for Scientific Research (KAKENHI),No. 23500573, No. 263500554, No. 17K01431 and No. 20K12700Grant of the Princess Takamatsu Cancer Research Fund,No. 13-24505Terumo Life Science Foundation,No. 15-I101 and No. 20-III119
文摘Therapeutic flexible endoscopic robotic systems have been developed primarily as a platform for endoscopic submucosal dissection(ESD)in the treatment of earlystage gastrointestinal cancer.Since ESD can only be performed by highly skilled endoscopists,the goal is to lower the technical hurdles to ESD by introducing a robot.In some cases,such robots have already been used clinically,but they are still in the research and development stage.This paper outlined the current status of development,including a system by the author’s group,and discussed future challenges.
基金the TBRS grant from the Research Grant Council of the Hong Kong Special Administrative Region Government(T42-717/20-R)the City University research grant(CityU11206818).
文摘The development of strain sensors with both superior sensitivity(gauge factor(GF)>100)and broad strain-sensing range(>50%strain)is still a grand challenge.Materials,which demonstrate significant structural deformation under microscale motion,are required to offer high sensitivity.Structural connection of materials upon large-scale motion is demanded to widen strainsensing range.However,it is hard to achieve both features simultaneously.Herein,we design a crepe roll structure-inspired textile yarn-based strain sensor with one-dimensional(1D)-two-dimensional(2D)nanohybrid strain-sensing sheath,which possesses superior stretchability.This ultrastretchable strain sensor exhibits a wide and stable strain-sensing range from microscale to large-scale(0.01%–125%),and superior sensitivity(GF of 139.6 and 198.8 at 0.01%and 125%,respectively)simultaneously.The strain sensor is structurally constructed by a superelastic 1D-structured core elastomer polyurethane yarn(PUY),a novel high conductive crepe roll-structured(CRS)1D-2D nanohybrid multilayer sheath which assembled by 1D nanomaterials silver nanowires(AgNWs)working as bridges to connect adjacent layers and 2D nanomaterials graphene nanoplates(GNPs)offering brittle lamellar structure,and a thin polydopamine(PDA)wrapping layer providing protection in exterior environment.During the stretching/deformation process,microcracks originate and propagate in the GNPs lamellar structure enable resistance to change significantly,while AgNWs bridge adjacent GNPs to accommodate applied stress partially and boost strain.The 1D crepe roll structure-inspired strain sensor demonstrates multifunctionality in multiscale deformative motion detection,such as respiratory motions of Sprague–Dawleyw rat,flexible digital display,and proprioception of multi-joint finger bending and antagonistic flexion/extension motions of its flexible continuum body.