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Low-carbon and Energy-saving Designs Preserving Primitive Ecological Conditions——With the Planning of Ancient Banyan Park in Mengshan County,Guangxi,China as a Case Study 被引量:1
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作者 叶明琴 《Journal of Landscape Research》 2011年第5期27-31,共5页
It was proposed that park planning should be based on local economic development,should focus on the preservation of primitive ecological conditions and the application of low-carbon and energy-saving concepts.The pla... It was proposed that park planning should be based on local economic development,should focus on the preservation of primitive ecological conditions and the application of low-carbon and energy-saving concepts.The planning of Ancient Banyan Park in Mengshan County by following the principles of respecting local history and culture,improving functions and supporting facilities,human-centered,overall planning and all-around consideration,respecting characteristics of the local area(the planning site),satisfying operation requirements of the park,applying low-carbon and energy-saving concepts,and avoiding over-engineering,aimed at protecting natural images of the park,primitive history,culture and characteristics of the local area and providing a space for local residents' various activities.Modern aesthetic forms were combined,cultural connotation of natural environment stressed to build a landscape space system of the Ancient Banyan Park that matches well with environment of the planning site.The park was designed into 4 functional areas:sport area,fitness plaza area,garden recreational area and ancient banyan cultural area.Different functions of these subareas were taken into consideration to create conservation-minded garden landscapes which were both independent and unified. 展开更多
关键词 GARDEN PLANNING ORIGINAL ecological conditions Low-carbon energy-saving
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Research on the cognitive process of building energy-saving reminder information: Review and prospects
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作者 MA Hui XIN Yi-xuan 《Ecological Economy》 2024年第4期372-389,共18页
Traditional building energy-saving research focuses on technical energy-saving and energy system energy-saving,while neglecting the study of personnel's energy-consumption behavior during the building operation ph... Traditional building energy-saving research focuses on technical energy-saving and energy system energy-saving,while neglecting the study of personnel's energy-consumption behavior during the building operation phase.In order to explore people's cognitive process of building energy-saving information,this paper focuses on the representativeness of the research on building energy-saving reminder information.The results are summarized,sorted out and analyzed.Based on relevant research at home and abroad,this paper reviews the conceptual connotation of building energy-saving reminder information,research methods and influencing factors on the recognition of building energy-saving reminder information.Finally,it summarizes the research landscape of the cognitive process of building energy-saving reminder information and analyzes the existing research.In light of the shortcomings,three major research directions are proposed in the future:integrating research scenarios and focusing on the interaction of multiple scenarios in the Chinese cultural environment;broadening research methods to explore the diversity and feasibility of emerging research methods;increasing the time span and improving experimental design dynamic and continuous. 展开更多
关键词 perception of energy-saving cue messages energy-saving behavior theoretical basis influencing factors review and prospects
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Energy-Saving Distributed Flexible Job Shop Scheduling Optimization with Dual Resource Constraints Based on Integrated Q-Learning Multi-Objective Grey Wolf Optimizer
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作者 Hongliang Zhang Yi Chen +1 位作者 Yuteng Zhang Gongjie Xu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第8期1459-1483,共25页
The distributed flexible job shop scheduling problem(DFJSP)has attracted great attention with the growth of the global manufacturing industry.General DFJSP research only considers machine constraints and ignores worke... The distributed flexible job shop scheduling problem(DFJSP)has attracted great attention with the growth of the global manufacturing industry.General DFJSP research only considers machine constraints and ignores worker constraints.As one critical factor of production,effective utilization of worker resources can increase productivity.Meanwhile,energy consumption is a growing concern due to the increasingly serious environmental issues.Therefore,the distributed flexible job shop scheduling problem with dual resource constraints(DFJSP-DRC)for minimizing makespan and total energy consumption is studied in this paper.To solve the problem,we present a multi-objective mathematical model for DFJSP-DRC and propose a Q-learning-based multi-objective grey wolf optimizer(Q-MOGWO).In Q-MOGWO,high-quality initial solutions are generated by a hybrid initialization strategy,and an improved active decoding strategy is designed to obtain the scheduling schemes.To further enhance the local search capability and expand the solution space,two wolf predation strategies and three critical factory neighborhood structures based on Q-learning are proposed.These strategies and structures enable Q-MOGWO to explore the solution space more efficiently and thus find better Pareto solutions.The effectiveness of Q-MOGWO in addressing DFJSP-DRC is verified through comparison with four algorithms using 45 instances.The results reveal that Q-MOGWO outperforms comparison algorithms in terms of solution quality. 展开更多
关键词 Distributed flexible job shop scheduling problem dual resource constraints energy-saving scheduling multi-objective grey wolf optimizer Q-LEARNING
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脑胶质瘤免疫治疗中CAR-T细胞的机制和研究进展
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作者 陈逸苒 赵亚宁 +3 位作者 王一鸣 任子阳 张世渊 胡涛 《中华神经外科疾病研究杂志》 CAS 2025年第1期120-123,共4页
脑胶质瘤,尤其是胶质母细胞瘤,是侵袭性极高且难以治疗的原发性颅内肿瘤,具有复发率高、死亡率高等临床特点。传统治疗手段如手术、放疗和化疗的效果有限,因此寻找新的治疗策略成为当前脑胶质瘤治疗领域研究的重点之一。免疫治疗在肿瘤... 脑胶质瘤,尤其是胶质母细胞瘤,是侵袭性极高且难以治疗的原发性颅内肿瘤,具有复发率高、死亡率高等临床特点。传统治疗手段如手术、放疗和化疗的效果有限,因此寻找新的治疗策略成为当前脑胶质瘤治疗领域研究的重点之一。免疫治疗在肿瘤治疗中越来越受到关注,其中嵌合抗原受体T细胞(CAR-T)免疫疗法作为一种新兴的治疗策略,展现出巨大的潜力。本文将系统地探讨CAR-T细胞在脑胶质瘤治疗中的作用机制、最新进展以及所面临的挑战,并展望了未来脑胶质瘤CAR-T细胞治疗的发展方向,以期为该领域的研究及临床应用提供参考。 展开更多
关键词 胶质瘤 car-T细胞 免疫治疗
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Operation optimization strategy of existing residential building energy-saving renovation market:From the perspective of subject behavior
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作者 GUO Han-ding LI Rui-jiao +1 位作者 QIN Guang-lei ZHANG Yin-xian 《Ecological Economy》 2024年第3期290-300,共11页
The energy-saving renovation of existing residential buildings is a crucial measure to achieve the strategic goal of energy conservation and emission reduction in China and build ecologically livable cities.This artic... The energy-saving renovation of existing residential buildings is a crucial measure to achieve the strategic goal of energy conservation and emission reduction in China and build ecologically livable cities.This article focuses on the perspective of subject behavior,starting from analyzing the current situation and difficulties of the operation of the energy-saving renovation market for existing residential buildings in China,drawing on the practical experience of the operation of the existing residential building energy-saving renovation market abroad.Based on principles such as systematicity,humanization,feasibility,and sustainability,the article constructs an operation optimization system of the existing residential building energy-saving renovation market from the perspective of subject behavior.In order to provide a reference for the healthy and orderly operation of the existing residential building energy-saving renovation market,this paper proposes implementation strategies for optimizing the operation of the existing residential building energy-saving renovation market.Suggestions are proposed from four aspects:optimizing the market environment,innovating the financing model,building the information sharing platform,and utilizing the synergies of the main subjects. 展开更多
关键词 the existing residential buildings energy-saving renovation market operation optimization strategy perspective of subject behavior
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Design of Low Carbon and Energy-saving New Rural Residential Buildings in Western Parts of Heilongjiang Province
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作者 陈雨祥 刘剑虹 《Agricultural Science & Technology》 CAS 2015年第11期2560-2562,共3页
It is researched that rural residential buildings in Heilongjieng consume high energy and the living environment is poor. The research aimed at designing low-carbon and energy-saving buildings in order to reduce energ... It is researched that rural residential buildings in Heilongjieng consume high energy and the living environment is poor. The research aimed at designing low-carbon and energy-saving buildings in order to reduce energy consumption by applying energy storage. Besides, the research used composite solar panel, waste- based inorganic foam materials, and polystyrene board as construction materials and integrated energy collection, living environment and farming by energy storage system. It is notable that the research would reduce pollution on environment caused by residential buildings, which coincides with national economy development and en- ergy strategy, promoting construction material industry development, with high social and economic benefits. 展开更多
关键词 Low-carbon and energy-saving New residential buildings Energy storage systern
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Energy-Saving Construction Technologies for Buildings
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作者 Jingjing Sun 《Journal of World Architecture》 2024年第3期43-48,共6页
The development of the construction industry is shifting towards low-carbon construction,so it is necessary to improve and optimize related construction concepts,methods,and processes.By improving resource and energy ... The development of the construction industry is shifting towards low-carbon construction,so it is necessary to improve and optimize related construction concepts,methods,and processes.By improving resource and energy control efficiency in building projects,minimizing construction waste,and reducing environmental impact,a foundation for the sustainable development of the industry can be established.This paper mainly analyzes the significance of low-carbon energy-saving construction technology and the control factors of construction,summarizes the status quo of the development of building energy-saving construction,and puts forward strategies for applying building energy-saving construction technology.These strategies serve to achieve low-carbon and energy-saving goals to promote the healthy development of energy-saving construction. 展开更多
关键词 Low-carbon energy-saving concept CONSTRUCTION energy-saving construction Thermal insulation technology Intelligent technology
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Application of Energy-Saving Materials in Architectural Design
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作者 Yajuan Liu 《Journal of World Architecture》 2024年第3期72-77,共6页
The conventional process of building construction is associated with issues such as the waste of construction materials and environmental pollution.Sustainable development highlights the importance of energy conservat... The conventional process of building construction is associated with issues such as the waste of construction materials and environmental pollution.Sustainable development highlights the importance of energy conservation and eco-friendly practices.It is essential to use energy-efficient and green materials in building designs to ensure the healthy growth of construction companies.This article discusses the advantages and principles of incorporating energy-saving materials in architectural design.It examines the strategies and critical control points for using energy-saving materials in architectural design,offering guidance for the sustainable development of the construction industry. 展开更多
关键词 energy-saving materials Architectural design Advantages Control strategy
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Exploration of Energy-Saving Technologies in Building Electrical System Design
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作者 Yong Zhang 《Journal of Electronic Research and Application》 2024年第4期28-33,共6页
Green energy conservation is the mainstream trend in the current development of the construction industry.The application of energy-saving technology in building electrical system design can effectively reduce energy ... Green energy conservation is the mainstream trend in the current development of the construction industry.The application of energy-saving technology in building electrical system design can effectively reduce energy consumption,avoid unnecessary energy consumption,and truly achieve energy conservation and environmental protection.Based on this,the article elaborates on the principles of energy-saving design in building electrical systems,and actively explores the application of energy-saving technologies from different perspectives such as optimizing power supply and distribution system design,adopting high-efficiency energy-saving lighting equipment,applying renewable energy,promoting smart home technology,and improving the efficiency of building electrical equipment. 展开更多
关键词 Building electrical system design energy-saving technology
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Development of Energy-Saving Devices for a 20,000DWT River–Sea Bulk Carrier
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作者 Kunpeng Chen Yuling Gao +1 位作者 Zhenping Huang Guoxiang Dong 《Journal of Marine Science and Application》 CSCD 2018年第1期131-139,共9页
A reduction of fuel consumption and an increase in efficiency are currently required for river–sea bulk carriers.Pre-swirl and ducted stators are widely used devices in the industry and efficiency gains can be obtain... A reduction of fuel consumption and an increase in efficiency are currently required for river–sea bulk carriers.Pre-swirl and ducted stators are widely used devices in the industry and efficiency gains can be obtained for single-screw and twin-screw vessels.Based on the hydrodynamic characteristics of the 20,000DWT river–sea bulk carrier,in this study,we proposed,designed,and tested a series of pre-swirl energy-saving devices(ESDs).The experimental results demonstrate that the proposed ESDs improved the propulsive efficiency and reduced the delivered power.The results confirm the success of our ESD for the 20,000DWT river–sea bulk carrier.We validated the role of Reynolds-averaged Navier–Stokes(RANS)computational fluid dynamics(CFD)in the twin-skeg river–sea vessel ESD design and found the circumferential arrangement and number of stators to be important factors in the design process. 展开更多
关键词 River–sea bulk carRIER energy-saving devices PRE-SWIRL STATORS Computational fluid dynamics RANS
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基于巨噬细胞的仿生递药系统和CAR疗法治疗脑胶质瘤的研究进展
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作者 朱菊红 李铭 +1 位作者 周东方 孙漩嵘 《杭州师范大学学报(自然科学版)》 2025年第1期57-63,共7页
治疗脑胶质瘤具有极大的挑战性,血脑屏障的存在使药物难以到达肿瘤部位发挥效果.利用天然细胞伪装的纳米颗粒作为药物载体,可以提高药物的穿透性和治疗效果.巨噬细胞因其独特的生物学特性而成为研究的焦点.将药物载体与巨噬细胞膜或外... 治疗脑胶质瘤具有极大的挑战性,血脑屏障的存在使药物难以到达肿瘤部位发挥效果.利用天然细胞伪装的纳米颗粒作为药物载体,可以提高药物的穿透性和治疗效果.巨噬细胞因其独特的生物学特性而成为研究的焦点.将药物载体与巨噬细胞膜或外泌体结合,构建的递药系统能够有效穿透血脑屏障并靶向肿瘤组织,不仅可以提高药物的生物利用度,还能减少药物对正常组织的毒副作用.文章总结了基于巨噬细胞的细胞膜和外泌体构建仿生纳米递药系统的研究,并对嵌合抗原受体巨噬细胞(chimeric antigen receptor macrophage,CAR-M)这一新兴治疗方式的未来进行了展望. 展开更多
关键词 脑胶质瘤 巨噬细胞 仿生递药系统 car-M
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A Review of the Applications of Nanofluids and Related Hybrid Variants in Flat Tube Car Radiators
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作者 Saeed Dinarvand Amirmohammad Abbasi Sogol Gharsi 《Fluid Dynamics & Materials Processing》 2025年第1期37-60,共24页
The present review explores the promising role of nanofluids and related hybrid variants in enhancing the efficiencyof flat tube car radiators.As vehicles become more advanced and demand better thermal performance,tra... The present review explores the promising role of nanofluids and related hybrid variants in enhancing the efficiencyof flat tube car radiators.As vehicles become more advanced and demand better thermal performance,traditional coolants are starting to fall short.Nanofluids,which involve tiny nanoparticles dispersed into standardcooling liquids,offer a new solution by significantly improving heat transfer capabilities.The article categorizesthe different types of nanofluids(ranging from those based on metals and metal oxides to carbon materials andhybrid combinations)and examines their effects on the improvement of radiator performance.General consensusexists in the literature that nanofluids can support better heat dissipation and enable accordingly the developmentof smaller and lighter radiators,which require less coolant and allow more compact vehicle designs.However,thisreview demonstrates that the use of nanofluids does not come without challenges.These include the long-termstability of these fluids and material compatibility issues.A critical discussion is therefore elaborated about thegaps to be filled and the steps to be undertaken to promote and standardize the use of these fluids in the industry. 展开更多
关键词 Flat tube car radiator nano-coolant stability metal-based nanoparticle heat transfer enhancement ethylene glycol
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没食子酸改善CAR-T诱发的细胞因子风暴研究
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作者 罗志强 史甲儒 +4 位作者 姜其耀 崔悦 李婧铭 郑静琦 于国华 《中南药学》 2025年第1期143-148,共6页
目的探讨没食子酸(GA)对嵌合抗原受体T细胞(CAR-T)免疫疗法诱发的细胞因子风暴的改善作用及药效机制。方法通过构建粒细胞-巨噬细胞集落刺激因子(GM-CSF)刺激的巨噬细胞炎症反应模型来模拟CAR-T诱发的细胞因子风暴,评估GA对巨噬细胞释... 目的探讨没食子酸(GA)对嵌合抗原受体T细胞(CAR-T)免疫疗法诱发的细胞因子风暴的改善作用及药效机制。方法通过构建粒细胞-巨噬细胞集落刺激因子(GM-CSF)刺激的巨噬细胞炎症反应模型来模拟CAR-T诱发的细胞因子风暴,评估GA对巨噬细胞释放的关键炎症因子白细胞介素(IL)-6和IL-1β的影响;后运用转录组测序的方法结合分子生物学实验验证,来预测GA对CAR-T诱发的细胞因子风暴的药效机制。结果GA作用后巨噬细胞中IL-6和IL-1β的mRNA和蛋白表达水平均显著降低,表明GA可以改善CAR-T诱发的细胞因子风暴;转录组测序结合差异基因KEGG通路富集分析表明,GA诱导的关键差异基因主要富集在NOD样受体信号通路等6条通路上;RT-qPCR实验验证发现,NOD样受体信号通路上的NLRP12、ASC、CASP5、CASP1基因的表达量在模型组中上升,GA干预后,表达均下降。结论GA可通过抑制NLRP12-ASC-CASP1/CASP5通路来抑制IL-6和IL-1β基因的表达,从而改善CAR-T诱发的细胞因子风暴。 展开更多
关键词 嵌合抗原受体T细胞免疫疗法 没食子酸 细胞因子风暴 IL-6 IL-1Β
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Energy-saving Architectural Designs for Relocation Residential Districts in North Jiangsu Province of China
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作者 黄婷 陈燕 《Journal of Landscape Research》 2011年第8期9-12,17,共5页
By investigating present relocation residential districts for peasants whose houses are removed for the unified planning of rural areas in north Jiangsu Province, as well as residents' feelings about the environme... By investigating present relocation residential districts for peasants whose houses are removed for the unified planning of rural areas in north Jiangsu Province, as well as residents' feelings about the environment of residential district, main architectural structures and energy consumption conditions, the indoor thermal environment, use of main heating and cooling facilities, residents' satisfaction on the acoustical and luminous environment, major space-enclosing structures and calculation of energy-saving designs are analyzed, and suggestions are given for the architectural design of relocation residential districts in the study area. It is stressed that the relationship between energy conservation and architectural layout, orientation, lighting, ventilation, selection of enclosing-structure materials, facade, color and style should be properly handled in the planning, and the focus is to control building orientation and shape coefficient, on the basis of which energy-saving designs of windows, exterior walls and roofs can be done. Energy consumption of present residential buildings is calculated and analyzed to bring forth new ideas to the energy-saving designs for relocation residential districts in north Jiangsu Province, and establish an architectural energy-saving system suitable for climatic and natural conditions of north Jiangsu to instruct the energy-saving designs of relocation residential districts in the study area. 展开更多
关键词 NORTH Jiangsu PROVINCE RELOCATION RESIDENTIAL district energy-saving buildings Strategies
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香蕉枯萎病菌内源报告基因Foc4carS的鉴定及其应用
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作者 彭军 曾凡云 +5 位作者 王艳玮 漆艳香 丁兆建 王少伶 谢艺贤 张欣 《热带作物学报》 CSCD 北大核心 2024年第5期873-885,共13页
香蕉枯萎病是由尖孢镰刀菌古巴转化型(Fusarium oxysporum f. sp. cubense, Foc)引起的香蕉毁灭性土传病害,其中4号生理小种(Foc4)能感染几乎所有的香蕉品系,危害最严重。carS基因通过调控下游car结构基因参与调控镰刀菌类胡萝卜素的生... 香蕉枯萎病是由尖孢镰刀菌古巴转化型(Fusarium oxysporum f. sp. cubense, Foc)引起的香蕉毁灭性土传病害,其中4号生理小种(Foc4)能感染几乎所有的香蕉品系,危害最严重。carS基因通过调控下游car结构基因参与调控镰刀菌类胡萝卜素的生物合成,本研究克隆鉴定了Foc4carS基因(FOIG_05085),Foc4carS蛋白具有典型的RING-finger蛋白结构域。利用分割标记法(Split-marker PCR)获得Foc4carS基因的融合片段,同时构建含有Foc4carS基因sgRNA591序列的pUC-fFuCas9-HTBNLS-hph-Foc4carS基因编辑载体,通过PEG介导的原生质体转化获得该基因的敲除突变体、回补突变体以及基因编辑敲除体,并对敲除和回补突变体的生物学特性和致病力进行分析。结果显示:ΔFoc4carS突变体的菌落直径、产孢量和致病力等生物学表型与野生菌株Foc4无显著差异,而ΔFoc4carS突变体菌落颜色呈深橙色,Foc4carS基因的缺失影响了次生代谢产物类胡萝卜素的生物合成;基因编辑的ΔFoc4carS(HDR)突变体不论是再生筛选板还是继代后的PDA平板,其菌落均出现典型的深橙色,表明Foc4carS可作为内源报告基因,在香蕉枯萎菌Foc4中进行基因质粒型CRISPR/Cas9编辑可行。 展开更多
关键词 香蕉枯萎菌Foc4 Foc4carS基因 类胡萝卜素 基因敲除 CRISPR/Cas9基因编辑
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CAR-T细胞治疗后复发/难治性多发性骨髓瘤患者的临床特征
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作者 王慧娟 陈文明 +1 位作者 耿传营 杨光忠 《中国癌症防治杂志》 CAS 2024年第5期549-553,共5页
目的分析嵌合抗原受体T(chimeric antigen receptor,CAR-T)细胞治疗后复发/难治多发性骨髓瘤(relapsed/refractory multiple myeloma,RRMM)患者的临床特征,初步探索此类患者未来可能的治疗策略。方法以2020年1月至2024年6月在首都医科... 目的分析嵌合抗原受体T(chimeric antigen receptor,CAR-T)细胞治疗后复发/难治多发性骨髓瘤(relapsed/refractory multiple myeloma,RRMM)患者的临床特征,初步探索此类患者未来可能的治疗策略。方法以2020年1月至2024年6月在首都医科大学附属北京朝阳医院住院治疗的RRMM患者为研究对象,分析CAR-T细胞治疗后复发的临床特征及生存情况。结果共收集14例符合条件的RRMM患者,均接受靶向BCMA的CAR-T细胞治疗,中位无进展生存时间为17个月(范围:3~47个月)。疾病复发进展时,1例仅表现为髓外复发,2例继发浆细胞白血病,11例为髓内复发;7例检查细胞遗传学,其中4例患者存在1个高危基因,1例患者存在2个高危基因。首次挽救治疗中,常用药物包括达雷妥尤单抗(6例)、泊马度胺(5例)、卡非佐米(3例),3例患者入组临床试验。13例患者可评价疗效,总有效率为61.5%(8/13),其中完全缓解率为30.8%(4/13),非常好的部分缓解率为23.1%(3/13)。中位随访时间为15个月(范围:1~32个月),中位无进展生存时间为7个月。截至末次随访,死亡6例,中位总生存期为32个月;1例患者出现第二肿瘤,类型为肺癌。结论接受CAR-T细胞治疗后RRMM患者常见多类药物耐药,挽救治疗疗效及预后不佳。 展开更多
关键词 多发性骨髓瘤 car-T细胞治疗 复发 难治 挽救治疗 预后
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Excavator Energy-saving Efficiency Based on Diesel Engine Cylinder Deactivation Technology 被引量:15
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作者 YANG Jing QUAN Long YANG Yang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2012年第5期897-904,共8页
The hydraulic excavator energy-saving research mainly embodies the following three measures: to improve the performance of diesel engine and hydraulic component, to improve the hydraulic system, and to improve the po... The hydraulic excavator energy-saving research mainly embodies the following three measures: to improve the performance of diesel engine and hydraulic component, to improve the hydraulic system, and to improve the power matching of diesel-hydraulic system-actuator. Although the above measures have certain energy-saving effect, but because the hydraulic excavator load changes frequently and fluctuates dramatically, so the diesel engine often works in high-speed and light load condition, and the fuel consumption is higher. Therefore, in order to improve the economy of diesel engine in light load, and reduce the fuel consumption of hydraulic excavator, energy management concept is proposed based on diesel engine cylinder deactivation technology. By comparing the universal characteristic under diesel normal and deactivated cylinder condition, the mechanism that fuel consumption can be reduced significantly by adopting cylinder deactivation technology under part of loads condition can be clarified. The simulation models for hydraulic system and diesel engine are established by using AMESim software, and fuel combustion consumption by using cylinder-deactivation-technology is studied through digital simulation approach. In this way, the zone of cylinder deactivation is specified. The testing system for the excavator with this technology is set up based on simulated results, and the results show that the diesel engine can still work at high efficiency with part of loads after adopting this technology; fuel consumption is dropped down to 11% and 13% under economic and heavy-load mode respectively under the condition of driving requirements. The research provides references to the energy-saving study of the hydraulic excavators. 展开更多
关键词 diesel engine cylinder deactivation hydraulic excavator energy-saving
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Green,Sustainable Architectural Bamboo with High Light Transmission and Excellent Electromagnetic Shielding as a Candidate for Energy-Saving Buildings 被引量:7
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作者 Jing Wang Xinyu Wu +5 位作者 Yajing Wang Weiying Zhao Yue Zhao Ming Zhou Yan Wu Guangbin Ji 《Nano-Micro Letters》 SCIE EI CAS CSCD 2023年第1期209-224,共16页
Currently,light-transmitting,energy-saving,and electromagnetic shielding materials are essential for reducing indoor energy consumption and improving the electromagnetic environment.Here,we developed a cellulose compo... Currently,light-transmitting,energy-saving,and electromagnetic shielding materials are essential for reducing indoor energy consumption and improving the electromagnetic environment.Here,we developed a cellulose composite with excellent optical transmittance that retained the natural shape and fiber structure of bamboo.The modified whole bamboo possessed an impressive optical transmittance of approximately 60%at 6.23 mm,illuminance of 1000 luminance(lux),water absorption stability(mass change rate less than 4%),longitudinal tensile strength(46.40 MPa),and surface properties(80.2 HD).These were attributed to not only the retention of the natural circular hollow structure of the bamboo rod on the macro,but also the complete bamboo fiber skeleton template impregnated with UV resin on the micro.Moreover,a multilayered device consisting of translucent whole bamboo,transparent bamboo sheets,and electromagnetic shielding film exhibited remarkable heat insulation and heat preservation performance as well as an electromagnetic shielding performance of 46.3 dB.The impressive optical transmittance,mechanical properties,thermal performance,and electromagnetic shielding abilities combined with the renewable and sustainable nature,as well as the fast and efficient manufacturing process,make this bamboo composite material suitable for effective application in transparent,energy-saving,and electromagnetic shielding buildings. 展开更多
关键词 Electromagnetic interference shielding Biomass material TRANSMITTANCE energy-saving BAMBOO
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BCMA CAR-T治疗复发/难治性多发性骨髓瘤患者的长期疗效和影响因素分析
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作者 喻敏 孔繁聪 +2 位作者 周玉兰 齐凌 李菲 《中国肿瘤临床》 CAS CSCD 北大核心 2024年第7期342-347,共6页
目的:评价靶向B细胞成熟抗原(B cell maturation antigen,BCMA)嵌合抗原受体T细胞(chimeric antigen receptor-T cell,CAR-T)治疗复发/难治性多发性骨髓瘤(relapsed/refractory multiple myeloma,R/R MM)的长期疗效和安全性。方法:回顾... 目的:评价靶向B细胞成熟抗原(B cell maturation antigen,BCMA)嵌合抗原受体T细胞(chimeric antigen receptor-T cell,CAR-T)治疗复发/难治性多发性骨髓瘤(relapsed/refractory multiple myeloma,R/R MM)的长期疗效和安全性。方法:回顾性分析2018年7月至2023年7月在南昌大学第一附属医院接受BCMA CAR-T细胞治疗20例R/R MM患者的临床资料,随访日期截至2023年12月31日。应用Kaplan-Meier生存分析评估患者总生存(overall survival,OS)率和无进展生存(progression-free survival,PFS)率,并统计相关不良反应。结果:20例R/R MM患者,既往中位治疗线数为3(2~6)线,客观缓解率(objective response rate,ORR)为75%,完全缓解(complete response,CR)率为50%;中位随访时间29个月,中位PFS为26个月。10例CR的患者中,5例在末次随访时仍处于缓解状态,缓解持续时间最短为6个月,最长48个月。亚组分析中,髓外浸润、17p缺失遗传学异常和肿瘤高负荷患者PFS显著更差(P<0.05)。细胞因子释放综合征(cytokine release syndrome,CRS)是CAR-T细胞治疗最常见的不良反应,发生率为90%,3~4级CRS的发生率为35%;远期不良反应少,未发生CAR-T细胞治疗相关死亡。结论:BCMA CAR-T细胞是当前R/R MM治疗的有效方案,不良反应可控。髓外浸润和肿瘤高负荷的患者治疗有效,但持久反应欠佳,如何进一步巩固和维持患者的疗效,值得进一步设计前瞻性的临床研究并探究其差异性。 展开更多
关键词 嵌合抗原受体修饰T细胞 复发/难治 多发性骨髓瘤
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Surface free energy of copper-zinc alloy for energy-saving of boiler 被引量:6
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作者 WANG Man LIANG Jinsheng +3 位作者 TANG Qingguo MING Xing MENG Junping DING Yan 《Rare Metals》 SCIE EI CAS CSCD 2006年第z1期324-327,共4页
Cu-Zn,Cu-Zn-Sn,Cu-Zn-Ni alloys were melted by vacuum smelter.The effect factors to the surface free energy of the alloys such as chemical composition,crystal structure and surface crystal lattice distortion etc.were i... Cu-Zn,Cu-Zn-Sn,Cu-Zn-Ni alloys were melted by vacuum smelter.The effect factors to the surface free energy of the alloys such as chemical composition,crystal structure and surface crystal lattice distortion etc.were investigated by OCA30 automatic contact angle test instrument,metallography microscope and XRD instrument etc.Results suggests:adding alloy element to Cu may increase its surface free energy,and the more kinds of alloy elements are added,the more surface free energy increases;the alloy element Sn an increase the surface free energy of Cu-Zn alloy;Cu-Zn alloy with fir-tree crystal structure,great phase discrepancy and obvious composition aliquation has greater surface free energy;Cu-Zn alloy with compounds and serious surface crystal lattice distortion has greater surface free energy. 展开更多
关键词 BOILER water treatment Cu-Zn alloy crystal structure contact angle surface free energy energy-saving
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