Defect Engineering:Can it Mitigate Strong Coulomb Effect of Mg^(2+)in Cathode Materials for Rechargeable Magnesium Batteries?

Rechargeable magnesium batteries(RMBs)have been considered a promising“post lithium-ion battery”system to meet the rapidly increasing demand of the emerging electric vehicle and grid energy storage market.However,the sluggish diffusion kinetics of bivalent Mg^(2+)in the host material,related to the strong Coulomb effect between Mg^(2+)and host anion lattices,hinders their further development toward practical applications.Defect engineering,regarded as an effective strategy to break through the slow migration puzzle,has been validated in various cathode materials for RMBs.In this review,we first thoroughly understand the intrinsic mechanism of Mg^(2+)diffusion in cathode materials,from which the key factors affecting ion diffusion are further presented.Then,the positive effects of purposely introduced defects,including vacancy and doping,and the corresponding strategies for introducing various defects are discussed.The applications of defect engineering in cathode materials for RMBs with advanced electrochemical properties are also summarized.Finally,the existing challenges and future perspectives of defect engineering in cathode materials for the overall high-performance RMBs are described.

Utilizing engineered extracellular vesicles as delivery vectors in the management of ischemic stroke:a special outlook on mitochondrial delivery

Ischemic stroke is a secondary cause of mortality worldwide,imposing considerable medical and economic burdens on society.Extracellular vesicles,serving as natural nanocarriers for drug delivery,exhibit excellent biocompatibility in vivo and have significant advantages in the management of ischemic stroke.However,the uncertain distribution and rapid clearance of extracellular vesicles impede their delivery efficiency.By utilizing membrane decoration or by encapsulating therapeutic cargo within extracellular vesicles,their delivery efficacy may be greatly improved.Furthermore,previous studies have indicated that microvesicles,a subset of large-sized extracellular vesicles,can transport mitochondria to neighboring cells,thereby aiding in the restoration of mitochondrial function post-ischemic stroke.Small extracellular vesicles have also demonstrated the capability to transfer mitochondrial components,such as proteins or deoxyribonucleic acid,or their sub-components,for extracellular vesicle-based ischemic stroke therapy.In this review,we undertake a comparative analysis of the isolation techniques employed for extracellular vesicles and present an overview of the current dominant extracellular vesicle modification methodologies.Given the complex facets of treating ischemic stroke,we also delineate various extracellular vesicle modification approaches which are suited to different facets of the treatment process.Moreover,given the burgeoning interest in mitochondrial delivery,we delved into the feasibility and existing research findings on the transportation of mitochondrial fractions or intact mitochondria through small extracellular vesicles and microvesicles to offer a fresh perspective on ischemic stroke therapy.

Targeting capabilities of engineered extracellular vesicles for the treatment of neurological diseases

Recent advances in research on extracellular vesicles have significantly enhanced their potential as therapeutic agents for neurological diseases.Owing to their therapeutic properties and ability to cross the blood–brain barrier,extracellular vesicles are recognized as promising drug delivery vehicles for various neurological conditions,including ischemic stroke,traumatic brain injury,neurodegenerative diseases,glioma,and psychosis.However,the clinical application of natural extracellular vesicles is hindered by their limited targeting ability and short clearance from the body.To address these limitations,multiple engineering strategies have been developed to enhance the targeting capabilities of extracellular vesicles,thereby enabling the delivery of therapeutic contents to specific tissues or cells.Therefore,this review aims to highlight the latest advancements in natural and targeting-engineered extracellular vesicles,exploring their applications in treating traumatic brain injury,ischemic stroke,Parkinson's disease,Alzheimer's disease,amyotrophic lateral sclerosis,glioma,and psychosis.Additionally,we summarized recent clinical trials involving extracellular vesicles and discussed the challenges and future prospects of using targeting-engineered extracellular vesicles for drug delivery in treating neurological diseases.This review offers new insights for developing highly targeted therapies in this field.

Reform of the Comprehensive Practical Course System for Mechanical and Electronic Engineering Majors Under the Background of New Engineering

Under the background of new engineering,the reform of the comprehensive practical course system for mechanical and electronic engineering majors actively responds to the challenges posed by the new round of technological revolution and industrial transformation to higher education,cultivating top-notch innovative intellectuals with comprehensive engineering qualities,meeting the requirements of being able to solve complex engineering problems rather than just cognitive capabilities,forming two core courses through reconstructing and reshaping the core courses of the major.The core courses include Drive,Measurement,and Control I and Drive,Measurement,and Control II,which highlight the comprehensive framework of mechanical and electronic engineering professional knowledge,continuing the comprehensive practical course system based on the unity of knowledge and practice,following the trend of new engineering,highlighting the practicality of professional innovation,assisting engineering education reform,and promoting high-quality development of new engineering professionals cultivation.

Features of Tropical Volcanic Rock and Soil of Jakarta-Bandung HSR and Engineering Countermeasures

The geological features of three types of tropical volcanic rock and soil distributed along Jakarta-Bandung high-speed railway(HSR),including pozzolanic clayey soil,mud shale and deep soft soil,are studied through field and laboratory tests.The paper analyzes the mechanism and causes of engineering geological problems caused by tropical volcanic rock and soil and puts forward measures to control subgrade slope instability by rationally determining project type,making side slope stability control and strengthening waterproofing and drainage.The“zero front slope”tunneling technology at the portal,the simplified excavation method of double-side wall heading and the cross brace construction method of arch protection within the semi-open cut row pile frame in the“mountainside”eccentrically loaded soft soil stratum are adopted to control the instability of tunnel side and front slopes,foundation pits and working faces;CFG or pipe piles shall be used to reinforce soft and expansive foundation or replacement measures shall be taken,and the scheme of blind ditch+double-layer water sealing in ballastless track section shall be put forward to prevent arching deformation of foundation;the treatment measures of CFG pile,pipe pile and vacuum combined piled preloading are adopted to improve the bearing capacity of foundation in deep soft soil section and solve the problems of settlement control and uneven settlement.These engineering countermeasures have been applied during the construction of Jakarta-Bandung HSR and achieved good results.

Compositional and Hollow Engineering of Silicon Carbide/Carbon Microspheres as High-Performance Microwave Absorbing Materials with Good Environmental Tolerance

Microwave absorbing materials(MAMs)characterized by high absorption efficiency and good environmental tolerance are highly desirable in practical applications.Both silicon carbide and carbon are considered as stable MAMs under some rigorous conditions,while their composites still fail to produce satisfactory microwave absorption performance regardless of the improvements as compared with the individuals.Herein,we have successfully implemented compositional and structural engineering to fabricate hollow Si C/C microspheres with controllable composition.The simultaneous modulation on dielectric properties and impedance matching can be easily achieved as the change in the composition of these composites.The formation of hollow structure not only favors lightweight feature,but also generates considerable contribution to microwave attenuation capacity.With the synergistic effect of composition and structure,the optimized SiC/C composite exhibits excellent performance,whose the strongest reflection loss intensity and broadest effective absorption reach-60.8 dB and 5.1 GHz,respectively,and its microwave absorption properties are actually superior to those of most SiC/C composites in previous studies.In addition,the stability tests of microwave absorption capacity after exposure to harsh conditions and Radar Cross Section simulation data demonstrate that hollow SiC/C microspheres from compositional and structural optimization have a bright prospect in practical applications.

Defect engineering in transition-metal(Fe,Co,andNi)-based electrocatalysts for water splitting

Electrocatalytic water splitting seems to be an efficient strategy to deal with increasingly serious environmental problems and energy crises but still suffers from the lack of stable and efficient electrocatalysts.Designing practical electrocatalysts by introducing defect engineering,such as hybrid structure,surface vacancies,functional modification,and structural distortions,is proven to be a dependable solution for fabricating electrocatalysts with high catalytic activities,robust stability,and good practicability.This review is an overview of some relevant reports about the effects of defect engineering on the electrocatalytic water splitting performance of electrocatalysts.In detail,the types of defects,the preparation and characterization methods,and catalytic performances of electrocatalysts are presented,emphasizing the effects of the introduced defects on the electronic structures of electrocatalysts and the optimization of the intermediates'adsorption energy throughout the review.Finally,the existing challenges and personal perspectives of possible strategies for enhancing the catalytic performances of electrocatalysts are proposed.An in-depth understanding of the effects of defect engineering on the catalytic performance of electrocatalysts will light the way to design high-efficiency electrocatalysts for water splitting and other possible applications.

基于C#语言与ArcGIS Engine 的开采沉陷预计系统开发

为了预计煤层开采引发的地表移动变形,基于极坐标系的概率积分法,借助C#语言和ArcGIS Engine组件工具库设计开发了矿区开采沉陷预计系统。开采沉陷预计系统适用于不规则形状的开采工作面,能够对开采区域地表各点不同开采时间后的下沉、水平移动、水平变形、倾斜、曲率进行预计,并对预计结果进行后处理,绘制地表移动变形云图。以陕西省某矿308工作面开采为例,根据工作面的开采条件、地层岩性等特征选取概率积分参数并代入本系统进行地表移动变形预计,将结果与实测地表移动变形进行对比分析。结果表明:使用该系统预计的地表下沉值与实测下沉值的相对误差小于10%,且下沉盆地形态与实际基本吻合,该系统的预计结果较为可靠,对矿区的开采沉陷预计具有一定的适用性。

Model-Based Systems Engineering Approach to Design a Human Settlement to Better Serve Displaced People

The challenge of transitioning from temporary humanitarian settlements to more sustainable human settlements is due to a significant increase in the number of forcibly displaced people over recent decades, difficulties in providing social services that meet the required standards, and the prolongation of emergencies. Despite this challenging context, short-term considerations continue to guide their planning and management rather than more integrated, longer-term perspectives, thus preventing viable, sustainable development. Over the years, the design of humanitarian settlements has not been adapted to local contexts and perspectives, nor to the dynamics of urbanization and population growth and data. In addition, the current approach to temporary settlement harms the environment and can strain limited resources. Inefficient land use and ad hoc development models have compounded difficulties and generated new challenges. As a result, living conditions in settlements have deteriorated over the last few decades and continue to pose new challenges. The stakes are such that major shortcomings have emerged along the way, leading to disruption, budget overruns in a context marked by a steady decline in funding. However, some attempts have been made to shift towards more sustainable approaches, but these have mainly focused on vague, sector-oriented themes, failing to consider systematic and integration views. This study is a contribution in addressing these shortcomings by designing a model-driving solution, emphasizing an integrated system conceptualized as a system of systems. This paper proposes a new methodology for designing an integrated and sustainable human settlement model, based on Model-Based Systems Engineering and a Systems Modeling Language to provide valuable insights toward sustainable solutions for displaced populations aligning with the United Nations 2030 agenda for sustainable development.

The Application of Thermomechanical Dynamics (TMD) to Thermoelectric Energy Generation by Employing a Low Temperature Stirling Engine

A thermoelectric generation Stirling engine (TEG-Stirling engine) is discussed by employing a low temperature Stirling engine and the dissipative equation of motion derived from the method of thermomechanical dynamics (TMD). The results and mechanism of axial flux electromagnetic induction (AF-EMI) are applied to a low temperature Stirling engine, resulting in a TEG-Stirling engine. The method of TMD produced thermodynamically consistent and time-dependent physical quantities for the first time, such as internal energy ℰ(t), thermodynamic work Wth(t), the total entropy (heat dissipation) Qd(t)and measure or temperature of a nonequilibrium state T˜(t). The TMD analysis produced a lightweight mechanical system of TEG-Stirling engine which derives electric power from waste heat of temperature (40˚CT100˚C) by a thermoelectric conversion method. An optimal low rotational speed about 30θ′(t)/(2π)60(rpm) is found, applicable to devices for sustainable, clean energy technologies. The stability of a thermal state and angular rotations of TEG-Stirling engine are specifically shown by employing properties of nonequilibrium temperature T˜(t), which is also applied to study optimal fuel-injection and combustion timings of heat engines.

Crack Prevention and Management Strategies in Bridge Engineering Construction

Cracking during construction is a common occurrence in modern bridge engineering that can directly impact the overall safety of the bridge.Therefore,it is essential to focus on preventing and controlling cracks.As the construction technology for bridge engineering has evolved,the internal quality of construction has significantly improved.However,the appearance quality remains a crucial factor that reflects the technical expertise of a construction company.Therefore,minimizing cracks and improving the appearance quality of concrete are critical issues that require the attention of construction units,supervision departments,and construction companies.This article will analyze the causes of cracking and suggest corresponding prevention and treatment methods.

Exploration of the Integration of Software Engineering Thinking into Embedded System Design Course

Engineering practice is the key bridge between college education and actual work in the industry.In order to deliver qualified talents with engineering quality to the industry,this paper explores integrating software engineering thinking into the Embedded System Design course.A practical and effective teaching mode is designed consisting of immersive learning,case-based learning,progressive practice,interactive learning,and autonomous learning.Through this teaching mode,multi-levels of closed-loop have been established including final project cycle closed-loop,testing cycle closed-loop,and product cycle closed-loop.During this process,students gradually transition to putting forward product requirements,carrying out design and development,thinking and solving problems,collaborating,and assuring quality from the perspective of software engineering.The practice results show that students’engineering quality has been significantly improved.

A Discussion on Innovative Methods for Green Engineering Management in Construction Engineering

With the rapid development of society,the construction industry has made significant progress.However,as environmental issues intensify,many construction projects contribute to pollution.In this context,applying green project management methods in construction can enhance energy conservation and environmental protection,reduce energy consumption and costs,and minimize environmental damage,promoting balanced development between the environment and the economy.Therefore,integrating green construction concepts into current construction projects is essential.Based on project requirements and construction activities,effective green project management strategies should be developed to improve management standards and promote more efficient green construction.This paper analyzes green project management in construction engineering and offers recommendations for reference.

基于Google earth engine渭-库绿洲果园遥感提取

针对干旱区果园大面积遥感提取困难、识别精度低等问题,本研究基于GEE(Google earth engine)平台,综合应用Sentinel-1/Sentinel-2影像构建特征集。通过对比原始特征组合、Jeffries-Matusita(J-M)距离、属性重要度3种优化方式,结合随机森林(Random forest,RF)分类方法,对比得到最佳优化方式,探索果园最优分类特征集。结果表明:识别效果最好的方案为G17 JM,总体精度为91.25%,kappa系数为0.89,面积精度为82.55%。最优特征集为B8_asm、B8_ent、B8_idm、NDVI re3、B6、B7、a、e、b、EVI、B11、B8A、B8、VV。使用J-M距离进行特征集优化,有效降低数据量、提高计算效率,更有利于精确遥感识别果园种植面积。表明GEE快速、准确获取果园种植面积的可行性,为获取果园动态变化提供强有力的基础。

Research on the Reform of Practical Teaching of Internet of Things Engineering in the Context of New Engineering

The emergence of new engineering disciplines has resulted in the growing trend of cross-discipline,and the enhancement of students’technical application ability has become the main teaching objective of engineering disciplines.For this reason,the Internet of Things(IoT)engineering program should be actively reformed,providing students with sufficient opportunities to improve their practical skills.This paper identifies the challenges within practical teaching of IoT engineering,delves into effective strategies for practical IoT teaching within the context of emerging engineering disciplines,and presents practical teaching experiences from the School of Information Engineering at Hainan University of Science and Technology as a case study.The aim is to offer guidance and insights to educators in this field.

基于Unreal Engine的虚拟现实技术在元宇宙图书馆中的应用

以虚拟现实技术作为研究切入点,探索元宇宙图书馆建设的技术实现路径。通过文献调研对比分析现有的虚拟现实技术,寻找一种适合高校图书馆自主研发的技术实现方法,并通过具体案例验证该方法的现实可行性。研究发现基于Unreal Engine的虚拟现实技术具有低成本、低代码量、可扩展等优点,适合经费少、计算机人才短缺的高校图书馆。对高校图书馆推进元宇宙图书馆建设具有一定的参考价值。

Biomimetic natural biomaterials for tissue engineering and regenerative medicine:new biosynthesis methods,recent advances,and emerging applications

Biomimetic materials have emerged as attractive and competitive alternatives for tissue engineering(TE)and regenerative medicine.In contrast to conventional biomaterials or synthetic materials,biomimetic scaffolds based on natural biomaterial can offer cells a broad spectrum of biochemical and biophysical cues that mimic the in vivo extracellular matrix(ECM).Additionally,such materials have mechanical adaptability,micro-structure interconnectivity,and inherent bioactivity,making them ideal for the design of living implants for specific applications in TE and regenerative medicine.This paper provides an overview for recent progress of biomimetic natural biomaterials(BNBMs),including advances in their preparation,functionality,potential applications and future challenges.We highlight recent advances in the fabrication of BNBMs and outline general strategies for functionalizing and tailoring the BNBMs with various biological and physicochemical characteristics of native ECM.Moreover,we offer an overview of recent key advances in the functionalization and applications of versatile BNBMs for TE applications.Finally,we conclude by offering our perspective on open challenges and future developments in this rapidly-evolving field.

基于ArcGIS Engine的风暴潮淹没适应气候变化策略辅助决策系统开发

本研究构建了基于ArcGIS Engine的风暴潮淹没适应气候变化策略辅助决策系统,将风暴潮淹没适应气候变化策略研究过程流程化和简单化,并提供7个面向用户开放的决策端口,辅助决策者做出科学的风暴潮淹没适应气候变化策略选择。以青岛市风暴潮淹没为例的系统应用,进一步验证了该系统能够切实提高研究过程的分析效率,为中国沿海地区的适应风暴潮灾害提供技术支持。

基于Google Earth Engine的八门湾红树林年际变化监测

该文基于Google Earth Engine(GEE)云平台,选择Landsat系列卫星数据,采用支持向量机(support vector machines,SVM)分类方法对八门湾地区进行地物类型分类,并基于分类结果监测该地区红树林年际变化。结果表明:红树林与陆地树木之间除红外波段外反射光谱曲线极其相似,利用红外波段特征指数并结合地形数据可进行有效区分,分类结果总体精度达到0.91;研究区红树林存在先减少后增加的变化趋势,在2009—2013年减少,2014—2016年基本保持不变,2017—2021年缓慢增加,红树林增加和坑塘减少时期是在“南红北柳”政策颁布之后,说明退塘还林政策成效显著;红树林主要是和坑塘相互变化转移,说明毁林造塘和退塘还林是影响该地区红树林变化的重要因素。红树林年际变化监测结果可以精细化分析红树林演变过程,并能精确量化红树林与其他土地类型的转化过程,从而在经济、政策上分析红树林演变因素,更有效地保护红树林。

Interface Engineering of Titanium Nitride Nanotube Composites for Excellent Microwave Absorption at Elevated Temperature

Currently,the microwave absorbers usually suffer dreadful electromagnetic wave absorption(EMWA)performance damping at elevated temperature due to impedance mismatching induced by increased conduction loss.Consequently,the development of high-performance EMWA materials with good impedance matching and strong loss ability in wide temperature spectrum has emerged as a top priority.Herein,due to the high melting point,good electrical conductivity,excellent environmental stability,EM coupling effect,and abundant interfaces of titanium nitride(TiN)nanotubes,they were designed based on the controlling kinetic diffusion procedure and Ostwald ripening process.Benefiting from boosted heterogeneous interfaces between TiN nanotubes and polydimethylsiloxane(PDMS),enhanced polarization loss relaxations were created,which could not only improve the depletion efficiency of EMWA,but also contribute to the optimized impedance matching at elevated temperature.Therefore,the TiN nanotubes/PDMS composite showed excellent EMWA performances at varied temperature(298-573 K),while achieved an effective absorption bandwidth(EAB)value of 3.23 GHz and a minimum reflection loss(RLmin)value of−44.15 dB at 423 K.This study not only clarifies the relationship between dielectric loss capacity(conduction loss and polarization loss)and temperature,but also breaks new ground for EM absorbers in wide temperature spectrum based on interface engineering.