The last decade has seen a steady proliferation in the use of tissue-engineered cell culture systems(Deforest and Anseth,2012),and these have been put to good use for studying neural axon growth and guidance(Li and...The last decade has seen a steady proliferation in the use of tissue-engineered cell culture systems(Deforest and Anseth,2012),and these have been put to good use for studying neural axon growth and guidance(Li and Hoffman-Kim,2008;Roy et al.,2013).These systems have been designed to more closely mimic the natural microenvironment of the developing or repairing nervous system and to enable spatiotemporal control over certain aspects of the microenvironment.展开更多
基金funded by the Oliver Fund of Tulane University,the Louisiana Board of Regents (LEQSF[2009-11]-RD-A-18)the NIH (NS065374)the NSF (CBET-1055990)
文摘The last decade has seen a steady proliferation in the use of tissue-engineered cell culture systems(Deforest and Anseth,2012),and these have been put to good use for studying neural axon growth and guidance(Li and Hoffman-Kim,2008;Roy et al.,2013).These systems have been designed to more closely mimic the natural microenvironment of the developing or repairing nervous system and to enable spatiotemporal control over certain aspects of the microenvironment.