Comparison of the Imaging Manifestations and Diagnostic Values of Multi-slice Spiral CT and Enhanced MRI Scans of Primary Liver Cancer(PLC)Intrahepatic Lesions

Objective:To compare and analyze the clinical diagnostic value of multi-slice spiral CT and enhanced MRI for primary liver cancer(PLC),and to summarize the imaging findings.Methods:The research subjects in this article were 50 patients with PLC who were admitted to our hospital from 2017 April to 2018 September.After the patients were admitted,they were examined by multi-slice spiral CT and enhanced MRI scanning,and the pathological diagnosis results were followed up.Relevant information was reviewed and analyzed.Results:The detection rate of multi-slice spiral CT was higher than that of MRI in the portal venous phase lesion detection.The difference was statistically significant(P<0.05).The detection rate of lesions in the arterial phase and delayed phase was not statistically significant(P>0.05);the diagnostic accuracy of multi-slice spiral CT was 85.96%,and the diagnostic accuracy of enhanced MRI scanning was 91.11%,which was not statistically significant(P>0.05).MRI scans showed the capsules of primary liver cancer better than CT,but the difference was not statistically significant(P>0.05).Conclusion:In conclusion,both multi-slice spiral CT and enhanced MRI can be used for the effective diagnosis of primary liver cancer intrahepatic lesions.The diagnostic value of the two is equivalent,but enhanced MRI has a slightly higher diagnostic accuracy and can be used as the preferred method.

Three-dimensional Imaging of Multi-slice Spiral CT in Bronchial Artery Correlative Study on Blood Supply of Central Lung Cancer and Its Clinical Significance

Objective: To evaluate three-dimensional bronchial artery imaging charactersin central lung cancer and applied values with multi-slice spiral CT (MSCT) to provide theoreticalevidence on blood supply and intervention therapy. Methods: Eighteen patients with central lungcancer underwent MSCT with real time helical thin-slice CT scanning. Three-dimensional bronchialartery reconstruction was done at the console work-station. The space anatomical characters ofbronchial artery were observed through different rotations. Results: For 6 cases, thethree-dimensional images of bronchial artery (33.33%) could exactly show the origins, the routes(lung inner segment and mediatism segment) and the diameters of bronchial arteries. Vision rate ofbronchial arteries was the highest in pulmonary artery stricture and truncation groups, and thevessels' diameter became larger apparently. These characters demonstrated blood supply of this kindof central lung cancer come from bronchial artery. Volume rendering images were the best ones amongthree-dimensional images. Conclusion: Three-dimensional imaging with MSCT in bronchial artery canreveal the anatomical characters of bronchial artery and provide theoretical evidence on bloodsupply and intervention therapy of central lung cancer.

Multi-slice spiral CT angiography in evaluating donors of living-related liver transplantation

BACKGROUND: During the past years, the number of liver transplantation has increased greatly, but the number of available organs has not increased. In view of the critical shortage of organs, the indications for living-related liver transplantation (LRLT) have broadened since experience with the procedure has been achieved. This study was undertaken to assess the value of multi-slice spiral CT (MSCT) angiography in evaluating the hepatic arterial and veinous anatomy of potential donors for LRLT. METHODS: MSCT was performed after intravenous injection of contrast material at 3 ml/s. The total dose was calculated as 2 ml/kg. Twenty LRLT donors (2 men and 18 women) were subjected to MSCT angiography of hepatic blood vessels. These were generated by volume rendering and maximum intensity projection, while curved planar reformation was added in 5 patients. RESULTS: We identified 10 important hepatic vascular variants in 9 of the 20 donors (4 arterial, 4 venous, and 2 portal venous variants). In hepatic arterial variants, two had a replaced right hepatic artery arising from the superior mesenteric artery, an accessory right hepatic artery from the superior mesenteric artery and a replaced left hepatic artery arising from the left gastric artery. In hepatic venous variants, three had an accessory inferior right hepatic vein and one had two accessory inferior right hepatic veins. In hepatic portal venous variants, two had trifurcation of the main portal vein. CONCLUSIONS: As a non-invasive and reliable method, MSCT angiography is of value in the clinical evaluation of LRLT donors. MSCT angiography should be recommended as a routine preoperative examination for potential LRLT donors.

Study on the combined value of multi-slice spiral CT in the diagnosis of elderly colorectal cancer colorectal cancer tumor markers

Objective:To investigate the value of tumor markers in colorectal cancer with multi-slice spiral CT in the diagnosis of elderly colorectal cancer.Methods:From January 2016 to September 2017 year period, 73 elderly patients with colorectal cancer treated in our hospital were selected as observation group;64 elderly patients with intestinal benign lesions were selected as control group during the same period. Serum samples were collected to detect contents of CEA, CA72-4, CA19-9 and CYFRA21-1 by Roche luminous immunoassay analyzer, and multi slice spiral CT was used.Results:Serum levels of CEA, CA72-4, CA19-9 and CYFRA21-1 levels of the observation group were significantly higher than that of the control group;the positive rate of CEA, CA72-4, CA19-9, CYFRA21-1 and their combined detection were all significantly higher than that of the control group;positive rate of MSCT in the observation group was higher than the control group;positive rates of tumor markers combining with MSCT examination of colorectal cancer were higher than that of combined detection of tumor markers and MSCT examination;but there was no significant difference in positive rate of combined detection of tumor markers and the positive rate of MSCT detection of colorectal cancer.Conclusion:Colorectal cancer tumor markers combined with multi-slice spiral CT in the diagnosis of colorectal cancer in elderly has important research value, can significantly improve the positive rate of diagnosis.

Value of Multi-slice Spiral CT in the Diagnosis and Resectability of Pancreatic Cancer

Objective:To analyze the value of multislice spiral CT in the diagnosis and resectability of pancreatic cancer.Method:56 patients with pancreatic cancer treated in our hospital from January 2018 to October 2019 were selected as the research subjects.All patients underwent multi-phase scanning by multislice spiral CT.According to the results of the images,observe whether the pancreatic cancer has affected the blood vessels surrounding the pancreas,evaluate the resectability based on the results of the examination,and analyze the final results of the operation which was taken as the standard.Results:all the 56 cases presented slightly low density or equal density,and 28 cases had complete outline.Multi-slice spiral assessment of patients’vascular invasion types found that 192 branches can be resected with 70 branches cannot;Multi-slice spiral assessment of the main arterial and venous invasion grades around the pancreas of the patients found that 212 branches can be resected with 50 branches cannot;Multi-slice spiral CT was used to evaluate the resectability of pancreatic cancer compared with surgical results.The accuracy of resectable types of vascular invasion was 72.52%;the accuracy of resectable vascular invasion grades was 79.39%.Conclusion:the application of multi-slice spiral CT in the diagnosis of pancreatic cancer can provide a clear understanding of the condition of vascular invasion and distant metastasis,and the accuracy of assessing resection can reach more than 70.00%,which provides a reference for clinical application.

Diagnostic Value of Spiral CT Chest Enhanced Scan in Adult with Active Pulmonary Tuberculosis

Aim:To explore the diagnostic value of spiral CT chest enhanced scan for adults with active pulmonary tuberculosis.Methods:The clinical data of 60 adult patients with active pulmonary tuberculosis who were treated in our hospital from January 2018 to November 2019 were retrospectively analyzed.All patients underwent conventional chest radiography and spiral CT chest enhanced scan.The number of tuberculosis diagnosis,the detection rate of special site lesions,and the detection rate of active pulmonary tuberculosis signs by the two methods were compared.Results:In 60 patients,the pathological results confirmed the existence of 75 tuberculosis lesions.The detection rate of spiral CT was 98.67%,which was not statistically significant compared with the detection rate of 92.00%(P>0.05)in the conventional chest X-ray.The detection rate of spiral CT enhanced scans for tuberculosis lesions in special sites was 100.00%,which was significantly higher than that of conventional chest X-ray of 7.69%,and the accuracy rate of active pulmonary tuberculosis signs was 98.85%higher than that of conventional chest X-ray of 79.31%.P<0.05).The difference was statistically significant(P<0.05).Conclusion:Spiral CT chest enhanced scan can not only find special tuberculosis lesions that cannot be detected by conventional chest radiography,but also accurately determine active pulmonary tuberculosis in adults,which is of high diagnostic value.

多层螺旋CT、肠腔充盈超声造影单独及联合检查对结肠癌的诊断价值

目的探讨多层螺旋CT、肠腔充盈超声造影单独及联合检查对结肠癌的诊断价值。方法选取98例结肠癌患者,术前均行多层螺旋CT、肠腔充盈超声造影检查。以病理检查结果为金标准,比较多层螺旋CT、肠腔充盈超声造影单独及联合检查对结肠癌、淋巴结转移及对结肠癌T分期的诊断符合率。结果病理检查结果显示,98例结肠癌患者中淋巴结转移35例。多层螺旋CT、肠腔充盈超声造影联合检查诊断结肠癌的符合率高于二者单独检查,差异有统计学意义(P﹤0.05);多层螺旋CT、肠腔充盈超声造影单独及联合检查诊断结肠癌淋巴结转移的符合率比较,差异无统计学意义(P﹥0.05)。病理检查结果显示,结肠癌T1~2期25例,T3期54例,T4期19例。多层螺旋CT、肠腔充盈超声造影联合检查诊断结肠癌T3、T4期的符合率均高于二者单独检查(P﹤0.05)。结论多层螺旋CT联合肠腔充盈超声造影检查对结肠癌的诊断价值较高。

Using receiver operating characteristic curves to evaluate the diagnostic value of the combination of multislice spiral CT and alpha-fetoprotein levels for small hepatocellular carcinoma in cirrhotic patients

BACKGROUND： The various combination of multiphase enhancement multislice spiral CT （MSCT） makes the diagno- sis of a small hepatocellular carcinoma （sHCC） on the back- ground of liver cirrhosis possible. This study was to explore whether the combination of MSCT enhancement scan and alpha-fetoprotein （AFP） level ficiency for sHCC. could increase the diagnostic ef- METHODS： This study included 35 sHCC patients and 52 cir- rhotic patients without image evidence of HCC as a control group. The diagnoses were made by three radiologists em- ploying a 5-point rating scale, with postoperative pathologic results as the gold standard. Receiver operating characteristic （ROC） curve analysis was performed to evaluate the diag- nostic value of the three MSCT combination modes （arterial phase＋portal-venous phase, arterial phase＋delayed phase, arterial phase＋portal-venous phase＋delayed phase） and AFP levels for sHCC on the background of liver cirrhosis. RESULTS： The area under ROC curve （AUC）, sensitivity, and specificity of the combination of arterial phase＋portal- venous phase＋delayed phase were 0.93, 93%, and 82%, respectively. The average AUC of the arterial phase＋portal- venous phase＋delayed phase combination was significantly greater than that of the arterial phase＋portal-venous phase （AUC=0.84, P=0.01） and arterial phase＋delayed phase （AUC=0.85, P=0.03）. Arterial phase＋portal-venous phase had a smaller AUC （0.84） than arterial phase＋delayed phase （0.85）, but the difference was insignificant （P=0.15）. After combining MSCT enhancement scan with AFP, the AUC, sensitivity, and specificity were 0.95, 94%, and 83%, respectively, indicating a greatly increased diagnostic efficiency for sHCC. CONCLUSIONS： The combination of AFP and 3 phases MSCT enhancement scan could increase the diagnostic efficiency for sHCC on the background of liver cirrhosis. The application of ROC curve analysis has provided a new method and reference in HCC diagnosis.

术前多排螺旋CT三期增强扫描对非小细胞肺癌纵隔淋巴结转移的诊断价值

目的探讨多排螺旋CT(MSCT)三期增强扫描对非小细胞肺癌(NSCLC)纵隔淋巴结转移(MLNM)中的术前诊断价值。方法回顾性分析80例NSCLC患者的临床资料,术前均行MSCT三期增强扫描,以术后病理结果为金标准,使用Kappa一致性检验评价MSCT三期增强扫描在术前诊断MLNM的诊断效能。结果术后病理检查证实80例NSCLC患者中,N0期31例,N1期24例,N2期25例,其中MLNM 25例(31.25%);术前MSCT诊断N0期34例,N1期24例,N2期22例,术前MSCT对NSCLC患者N分期诊断与术后病理一致性一般(Kappa=0.735);25例合并MLNM患者中,术前MSCT确诊19例,其对NSCLC患者MLNM的诊断与病理结果一致性一般(Kappa=0.531),其诊断的灵敏度、特异度、准确度、阳性预测值和阴性预测值分别为76.00%、80.00%、78.75%、63.33%和88.00%;纵隔淋巴结转移率在不同肿瘤直径、胸膜凹陷与否、不同肿大淋巴结位置、累及粗大肺静脉与否以及不同淋巴结短径的NSCLC患者间比较均有统计学意义(P<0.05)。结论术前MSCT三期增强扫描诊断NSCLC患者MLNM具有一定的准确性,结合原发病灶大小、胸膜凹陷、肿大淋巴结位置、累及粗大肺静脉等多方面信息可为淋巴结清扫提供重要参考。

Spiral CT localization of pancreatic function-ing islet cell tumors

BACKGROUND: Surgeons are always concerned about the localization of pancreatic functioning islet cell tumor. If the tumor is accurately localized before operation, resection of the pancreatic body and tail without intention can be avoided. The purpose of this study was to evaluate spiral CT localization of pancreatic functioning islet cell tumors and CT techniques. METHODS: CT manifestations in 6 patients with clinically and pathologically proved pancreatic functioning islet cell tumors ware analyzed retrospectively. RESULTS: In 4 patients with insulinomas and 2 patients with glucagonomas, 5 were localized accurately by CT be- fore surgery and 1 was detected retrospectively. The en- hancement of tumors was greater than that of normal pan- creas in arterial phase and pancreatic parenchymal phase. Four patients showed mild high-density and 2, iso-density in the portal venous phase. CONCLUSION: Spiral CT multi-phase enhanced scan with 1.5 ml/kg contrast agent and 2-5 mm slice width can loca- lize functioning islet cell tumors accurately.

Spiral multi-phase CT in evaluating resectability of pancreatic carcinoma

Objectives: To evaluate the specific manifestations of pancreatic carcinoma on spiral multi-phase CT and its resectability before operation. Methods: Ninety-seven patients were confirmed oper- atively and pathologically. Enhanced CT scan was performed with intravenous injection bolus of ap- proximately 75-120 ml (1-1.5 ml/kg body weight) contrast medium at a rate of 2.5-3 ml/s. In 68 pa- tients receiving dual-phase scan, the delayed scan time of arterial and venous phases was 18-20 s and 60-70 s, respectively, and in 29 patients receiving three-phase scan, the delayed scan time of arterial, pancreatic and portal venous phases was 18 s, 40 s and 75 s, respectively, with a slice of 3-5 mm thick- ness, a pitch of 1-1.5, and a reconstruction interval of 2.5-4.8 mm. Results: Positive and negative predictive values of un- resectable tumors were 97.65% and 75.86%, respec- tively. The sensitivity and accuracy were 90.67% and 90. 72%, respectively. Positive predictive values of dual-phase and three-phase were 95.83% and 100%, respectively; negative predictive values were 75% and 77.78%, respectively. Conclusions: Spiral multi-phase CT is superior in re- vealing the involvement of peripancreatic vessels, the invasion of the neighboring organs, the size, shape and range of carcinoma, and the metastasis of liver and lymph node. The predictability of resection is obviously increased for patients with pancreatic car- cinoma.

三期增强CT扫描联合血清AFP和VEGF水平诊断肝细胞癌患者临床研究

目的探讨多层螺旋CT(MSCT)三期增强扫描联合血清甲胎蛋白(AFP)和血管内皮生长因子(VEGF)水平对肝内占位性病变的诊断价值。方法2021年1月~2022年12月我院诊治的肝内占位性病变患者82例,均接受MSCT平扫和三期增强扫描检查,采取细针穿刺活检或手术组织行常规病理学检查。采用免疫化学发光法检测血清AFP水平,采用ELISA法检测血清VEGF水平。绘制受试者工作特征曲线(ROC)并计算曲线下面积(AUC)分析三期增强CT扫描联合血清AFP和VEGF水平诊断肝细胞癌(HCC)的效能。结果在本组82例肝占位患者中,病理学检查诊断肝细胞癌(HCC)43例,局灶性增生性结节(FPN)39例,MSCT扫描诊断原发性肝癌(PLC)36例,诊断良性病灶46例;HCC病灶平扫及增强动脉期、门静脉期和延迟期CT值分别为(33.2±1.7)、(68.2±2.4)、(61.5±1.2)和(31.9±1.6),均显著低于FPN病灶【分别为(40.1±2.5)、(92.5±3.1)、(76.8±2.6)和(63.2±3.7),P<0.05】;HCC患者血清AFP和VEGF水平分别为(310.5±25.3)ng/mL和(97.6±62.1)ng/L,均显著高于FPN患者【分别为(23.6±3.2)ng/mL和(65.4±19.8)ng/L,P<0.05】;MSCT诊断恶性病变的灵敏度和特异度分别为81.4%和97.4%,采用CT联合血清指标诊断可以将诊断的灵敏度和特异度都提高到97.4%。结论应用三期增强CT扫描扫描联合血清AFP和VEGF水平对判断肝内占位性病变的性质有帮助,值得进一步研究。

思维导图引导干预在肺癌患者多层螺旋CT增强扫描中的应用价值

目的探讨思维导图引导干预在肺癌患者多层螺旋CT增强扫描中的应用价值。方法依据干预方法的不同将80例肺癌患者分为对照组和观察组,每组40例,对照组患者给予常规引导干预,观察组患者给予思维导图引导干预。比较两组患者的CT图像质量、心理状态[汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)]、检查依从性和对医护人员的满意度。结果观察组患者的CT图像质量优良率为92.50%,高于对照组患者的75.00%,差异有统计学意义(P﹤0.05)。干预后,两组患者HAMD、HAMA评分均低于本组干预前,观察组患者HAMD、HAMA评分均低于对照组,差异均有统计学意义(P﹤0.05)。观察组患者的检查总依从率为95.00%,高于对照组患者的75.00%,差异有统计学意义(P﹤0.05)。观察组患者对医护人员引导态度、引导及时性、引导正确性的满意度评分均明显高于对照组,差异均有统计学意义(P﹤0.01)。结论思维导图引导干预能够提高肺癌患者多层螺旋CT增强扫描的图像质量,缓解患者的负性心理状态,提高检查依从性及对医护人员的满意度。

多层螺旋CT增强联合动态增强磁共振功能成像评价结直肠癌术后局部复发/转移的临床价值

目的探究多层螺旋CT增强联合动态增强磁共振功能成像评价结直肠癌(CRC)术后局部复发/转移的临床价值。方法选取2019年10月至2021年10月期间本院收治的82例CRC患者,根据患者术后情况分为复发或转移组(36例)和未复发或转移组(46例);所有患者均进行多层螺旋CT增强和动态增强磁共振功能成像检查;绘制ROC曲线分析多层螺旋CT增强及转运常数(K^(trans))、反流速率常数(K_(ep))和血管外细胞外容积分数(V_(e))对CRC术后局部复发/转移的诊断价值;采用四格表分析多层螺旋CT增强联合动态增强磁共振功能成像评价CRC术后局部复发/转移的诊断价值。结果多层螺旋CT增强扫描检查的39例阳性患者中出现复发或转移有30例,未复发或转移的有9例,检查的43例阴性患者中出现复发或转移的有6例,未复发或转移的有37例。复发或转移组K^(trans)、K_(ep)和V_(e)均显著高于未复发或转移组(P<0.05)。根据ROC曲线得知,K^(trans)诊断CRC术后局部复发/转移的曲线下面积(AUC)为0.846,K_(ep)诊断CRC术后局部复发/转移的AUC为0.780,V_(e)诊断CRC术后局部复发/转移的AUC为0.861,多层螺旋CT增强诊断CRC术后局部复发/转移的AUC为0.819,四者联合诊断CRC术后局部复发/转移的AUC为0.987。多层螺旋CT增强在CRC术后局部复发/转移诊断中准确度为81.71%;动态增强磁共振功能成像在CRC术后局部复发/转移诊断中准确度为85.37%;二者联合检测在CRC术后局部复发/转移诊断中准确度为93.90%。结论多层螺旋CT增强联合动态增强磁共振功能成像能显著提高CRC术后局部复发/转移诊断效能,对于患者在术后随访监测有较高的临床价值。

螺旋CT动态增强扫描在孤立性肺结节良恶性鉴别诊断中的应用探讨

目的探讨螺旋CT动态增强扫描在孤立性肺结节(SPN)良恶性鉴别诊断中的应用价值。方法将103例SPN患者作为研究对象,均实施常规CT平扫及螺旋CT动态增强扫描。以穿刺或手术病理结果作为金标准,分析两种检查方法诊断结果;比较两种检查方法诊断效能;比较良恶性结节不同时期的CT值;比较良恶性结节的CT征象检出率。结果螺旋CT动态增强扫描中,恶性48例(真恶性45例,假恶性3例),良性55例(真良性53例,假良性2例);常规CT平扫中,恶性48例(真恶性35例,假恶性13例),良性55例(真良性43例,假良性12例)。以穿刺或手术病理结果作为金标准,螺旋CT动态增强扫描对恶性肺结节的诊断敏感度95.74%、特异度94.64%、准确度95.15%、恶性预测值93.75%、良性预测值96.36%均高于常规CT平扫的74.47%、76.79%、75.73%、72.92%、78.18%(P<0.05)。恶性结节在平扫期、增强后15 s的CT值与良性结节相当(P>0.05),而恶性结节在增强后30、60、120、180、240、300 s的CT值均高于良性结节(P<0.05)。恶性结节空泡征、棘突征检出率与良性结节相当(P>0.05);但恶性结节磨玻璃征、分叶征、毛刺征、血管集束、胸膜凹陷检出率分别为29.79%、61.70%、55.32%、44.68%、40.43%,均高于良性结节的3.57%、28.57%、16.07%、14.29%、7.14%(P<0.05)。结论螺旋CT动态增强扫描在SPN良恶性鉴别诊断中的应用效果显著,从CT值、CT征象上能有效鉴别良恶性结节,为临床诊断提供可靠依据。

128排上腹部增强多层螺旋CT在小肝癌诊断中的研究

目的探讨128排上腹部增强多层螺旋CT在小肝癌诊断中的效能。方法选取新乡市第一人民医院2021年1月至2023年10月收入的72例疑似小肝癌患者,所有患者均接受128排上腹部增强多层螺旋CT、MRI检查,并以病理结果为金标准,对比两者诊断效能。结果72例疑似小肝癌患者经病理检查结果显示53例为恶性(73.61%)、19例为良性(26.39%),128排上腹部增强多层螺旋CT中诊断准确率为94.44%,高于MRI的准确率(81.94%),差异有统计学意义(P<0.05);72例疑似小肝癌患者中,经病理明确病灶大小,病灶直径<2 cm为14例、2~5 cm为34例、>5 cm为24例。MRI与128排上腹部增强多层螺旋CT明确病灶大小情况,差异无统计学意义(P>0.05);53例小肝癌患者中,33例为肝细胞癌、8例为胆管细胞癌、6例为混合细胞癌、6例为转移性肝癌,MRI与128排上腹部增强多层螺旋CT肝癌类型确诊情况,差异无统计学意义(P>0.05)。结论128排上腹部增强多层螺旋CT疾病诊断准确率高于MRI检查,且在病灶大小确诊及肝癌类型确诊中具有较高的诊断效能,能用于临床疾病早期诊断,为临床医师诊疗方案的实施提供合理依据。

多层螺旋CT增强扫描技术在肝脏疾病诊断中的应用价值

目的探究多层螺旋CT增强扫描技术在肝脏疾病诊断中的应用价值。方法选取300例疑似肝脏疾病患者,采取多层螺旋CT增强扫描技术对其进行检查。以肝脏穿刺活检病理结果作为金标准,分析多层螺旋CT增强扫描技术的诊断效能(敏感度、特异度、阳性预测值、阴性预测值以及准确度)、一致性及影像学表现。结果300例疑似肝脏疾病患者中,金标准检查结果示216例为肝脏疾病,剩余84例为其他患者;多层螺旋CT增强扫描技术检查结果示肝脏疾病患者212例,其他患者88例。多层螺旋CT增强扫描技术诊断敏感度为95.83%(207/216)、特异度为94.05%(79/84)、准确度为95.33%(286/300)、阳性预测值为97.64%(207/212)、阴性预测值为89.77%(79/88)。多层螺旋CT增强扫描技术检查结果和肝脏穿刺活检病理结果一致较高(kappa=0.787)。216例确诊的肝脏疾病患者中,100例患者肝内存在较明显的病灶影。216例患者中20例患者肝内存在多发小强化病灶,有3例患者肝内多发小病灶在进行平扫以及超声检查后并未进行提示。在对患者进行二期扫描,即门静脉期扫描时图像显示216例患者下腔静脉、门静脉与其分支、脾静脉、肝静脉均能清晰显示,脾脏均匀强化,肝实质均匀强化。在一期扫描中强化病灶患者40例,在二期扫描中密度显著降低,表现为低密度影,其中12例患者门脉主干存在充盈缺损。在动脉期并未表现出显著变化的20例患者,在二期扫描中边缘表现为不规则强化,在进行三期扫描或延迟扫描时,该20例患者可见病灶造影剂逐步向中心进行充填,另外还有10例患者病灶在二期扫描时表现出不规则强化。在将患者图像与临床症状进行结合后发现,216例患者中,100例患者诊断为肝血管瘤,70例患者诊断为原发性肝癌,30例患者存在肝内多发转移以及门脉癌栓,还有16例患者诊断为肝脓肿。患者肝脏血液的主要供应来源为门静脉以及肝内动脉,其中肝总共血流中肝动脉占比在20%以上。结论对肝脏疾病患者进行诊断时实施多层螺旋CT增强扫描技术的诊断准确度较高,临床医师能够更全面的了解患者肝脏病灶及其周边情况,临床价值显著。

MSCT动态增强扫描及血清肿瘤标志物水平鉴别进展期胃癌和胃淋巴瘤的价值

目的探讨多层螺旋CT(MSCT)动态增强扫描及血清肿瘤标志物水平鉴别进展期胃癌和胃淋巴瘤的价值。方法选择2014年3月至2023年3月联勤保障部队第904医院收治的21例胃淋巴瘤(胃淋巴瘤组)及87例进展期胃癌(胃癌组)患者为研究对象。两组患者先行CT平扫,再行MSCT动态增强扫描,并检测血清癌胚抗原(CEA)、糖类抗原19-9(CA19-9)、糖类抗原125(CA125)水平。观察、记录两组患者胃黏膜状况、胃壁受累范围、胃腔狭窄程度、腹腔和腹膜后淋巴结肿大情况,以及平扫CT值和增强三期扫描的CT值,包括动脉期和门脉期的强化净增值,对比其强化程度、均匀度;对比两组患者的CEA、CA19-9、CA125水平。通过ROC曲线分析CT强化净增值和CT联合肿瘤标志物对胃癌和胃淋巴瘤的诊断效能。结果胃癌组出现黏膜白线征例数显著高于胃淋巴瘤组,胃癌组出现黏膜掀起征、腹腔及腹膜后淋巴结肿大例数显著少于胃淋巴瘤组,胃癌组胃壁侵犯范围<50%、胃腔僵硬及狭窄例数显著高于胃淋巴瘤组,差异有统计学意义(P<0.05)。胃癌组患者动脉期、门脉期、延迟期CT值及动脉期、门脉期强化净增值显著高于胃淋巴瘤组患者,差异有统计学意义(P<0.05)。两组患者平扫CT值比较差异无统计学意义(P>0.05),但在强化程度和强化均匀度上差异有统计学意义(P<0.05)。对比胃癌组与胃淋巴瘤组患者的CEA水平,前者显著高于后者,差异有统计学意义(P<0.05),而CA19-9、CA125水平组间比较差异无统计学意义(P>0.05)。ROC曲线分析结果显示,CT动脉期强化净增值、门脉期强化净增值、动脉期与门脉期强化净增值联合及CT联合肿瘤标志物诊断胃癌和胃淋巴瘤的曲线下面积分别为0.829、0.799、0.874、0.938,敏感度分别为0.837、0.816、0.885、0.943。结论MSCT动态增强扫描及血清CEA水平在鉴别进展期胃癌和胃淋巴瘤中具有一定价值。

多层螺旋CT增强扫描联合EGFR突变检测在肺癌患者中的诊断效果

目的:探讨多层螺旋CT(MSCT)增强扫描联合表皮生长因子受体(EGFR)突变检测在肺癌患者中的诊断效果。方法:选取2021年1月—2023年1月宜春市第二人民医院经组织病理学检查确诊的80例肺癌患者(肺癌组)和50例肺良性病变患者(肺良性病变组)为研究对象,均行MSCT增强扫描检查,并采用xTAG70plex液相芯片技术检测EGFR突变情况。比较两组MSCT增强扫描征象、EGFR突变阳性率,并分析MSCT增强扫描联合EGFR突变检测对肺癌的诊断效能。结果:肺癌组MSCT增强扫描征象中肺组织边界不清晰、毛刺征、血管集束征、支气管充气征、胸膜凹陷征比例均高于肺良性病变组(P<0.05);两组病灶位置、病灶形状及内部结构比较,差异均无统计学意义(P>0.05)。肺良性病变组EGFR突变阳性率为6.00%(3/50),肺癌组为63.75%(51/80),肺癌组EGFR突变阳性率高于肺良性病变组(χ^(2)=42.257,P<0.05)。肿瘤最大直径≥5 cm患者EGFR突变阳性率高于<5 cm患者,Ⅲ、Ⅳ期患者EGFR突变阳性率高于Ⅰ、Ⅱ期患者,低分化患者EGFR突变阳性率高于中、高分化患者,淋巴结转移患者EGFR突变阳性率高于无淋巴结转移患者(P<0.05);两组不同病理类型肺癌EGFR突变阳性率比较,差异无统计学意义(P>0.05)。受试者操作特征(ROC)曲线显示,MSCT增强扫描联合EGFR突变检测诊断肺癌的敏感度为93.7%,特异度为92.0%,均高于MSCT增强扫描、EGFR突变检测的78.5%、87.2%和76.0%、78.5%。结论:MSCT增强扫描联合EGFR突变检测能提高肺癌诊断效能,可对肺癌临床筛查诊断、制订治疗方案提供一定的参考依据。

多层螺旋CT增强扫描对肝脏占位性病变图像质量及诊断效能的影响

目的:探讨肝脏占位性病变采用多层螺旋CT(MSCT)增强扫描对图像质量及诊断效能的影响。方法:选取2022年1月—2023年6月诏安县医院收治的92例肝脏占位性病变患者,均接受MSCT平扫、MSCT增强扫描,以临床症状、病理检查及随访结果作为金标准,比较不同检查方法的图像质量、诊断效能及病灶检出情况,并分析不同病灶的图像特征。结果:MSCT增强扫描图像质量优良率为97.83%,较MSCT平扫的90.22%高,差异有统计学意义(P<0.05);92例肝脏占位性病变患者中,确诊为阳性31例,阴性61例,MSCT平扫的敏感度、特异度、阳性预测值、阴性预测值分别为74.19%、81.97%、67.65%、86.21%,MSCT增强扫描分别为96.77%、95.08%、90.91%、98.31%,MSCT增强扫描的敏感度、特异度、阳性预测值、阴性预测值均较MSCT平扫高,差异有统计学意义(P<0.05);MSCT增强扫描肝癌病灶检出准确率较MSCT平扫高,差异有统计学意义(P<0.05);肝血管瘤有清晰边界,呈稍低密度影,动脉期病灶对比增强,边缘呈片状或结节状,静脉期边缘强化向中央发展;肝囊肿呈低密度影,病灶内无明显钙化及强化现象;局灶性结节增生呈低密度改变,也可呈等密度改变,增强扫描时可见内有中央瘢痕填充,或出现高密度影;肝癌边界模糊不清,整体呈低密度影,部分区域可见等密度或高密度影,动脉期强化效果明显,静脉期强化程度降低。结论:MSCT增强扫描诊断肝脏占位性病变,能够提高图像质量,辅助医师准确鉴别病灶类型,清晰显示病灶特征。