Aim: To screen hepatitis B and C in occupational setting. Methods: Cross-sectional study multicenter in 16 enterprises (one occupational exposure;5602 agents). Screening was preceded by information, sensibilisation an...Aim: To screen hepatitis B and C in occupational setting. Methods: Cross-sectional study multicenter in 16 enterprises (one occupational exposure;5602 agents). Screening was preceded by information, sensibilisation and informed consenting physician labor, labor union and agents. Hepatitis B surface antigen (HBsAg) and antibodies anti-hepatitis C (Elisa, third generation) were tested in all. For those with HBsAg positive, this test was completed by IgM and IgG, anti HBc, HBeAg, antibodies anti HBe, transaminases and HBB DNA;for those with positive anti-VHC antibodies, test was completed by transaminases and VHC’s RNA. Results: Rate of participation was 76.2% (4268/5602 labors). HBsAg or hepatitis C antibodies were positives in 425 (9.9%) of cases (HBsAg positive: 8.48%;Hepatitis C Antibodies positives: 1.50%;both: 0.05%). In HBsAg positive, viral replication and cytolysis were seen respectively in 2.5 % and 18.2%. According with transaminases, serologic markers and viral load, immunotolerance, inactive and immuno active phase were suspected in 0.56%, 80.9% and 1.6% of cases. In hepatitis C antibodies positives persons, any had viral replication but cytolysis was observed in 33.3% (n = 21). HBsAg was significantively (p < 0.00001) higher in exposed occupational enterprise versus non-occupational setting (14.4% vs 7.8%). They were no differences (p = 0.71) about hepatitis C antibodies in the two setting (1.8% vs 1.7%). Conclusion: Prevalence of HBsAg and hepatitis C antibodies was high in occupational setting in hepatitis endemic country. It’s important to screen all of person in these setting with no consideration with blood exposed or not exposed enterprise.展开更多
健康企业建设是健康中国建设的细胞基础,是健康城市建设的具体指标之一,探索健康企业建设有效途径和模式是建设过程的重要主题。文章将问题式学习(problem based learning,PBL)教学思路应用于健康企业的创建实践中,提出基于PBL的健康企...健康企业建设是健康中国建设的细胞基础,是健康城市建设的具体指标之一,探索健康企业建设有效途径和模式是建设过程的重要主题。文章将问题式学习(problem based learning,PBL)教学思路应用于健康企业的创建实践中,提出基于PBL的健康企业创建模式并分析实践效果,认为该模式可以让企业管理者充分参与寻求问题解决措施的过程,转变企业管理者的健康观念、学会健康企业创建理念,起到“授之以渔”的效果,适合在健康企业创建过程中推广应用。展开更多
文摘Aim: To screen hepatitis B and C in occupational setting. Methods: Cross-sectional study multicenter in 16 enterprises (one occupational exposure;5602 agents). Screening was preceded by information, sensibilisation and informed consenting physician labor, labor union and agents. Hepatitis B surface antigen (HBsAg) and antibodies anti-hepatitis C (Elisa, third generation) were tested in all. For those with HBsAg positive, this test was completed by IgM and IgG, anti HBc, HBeAg, antibodies anti HBe, transaminases and HBB DNA;for those with positive anti-VHC antibodies, test was completed by transaminases and VHC’s RNA. Results: Rate of participation was 76.2% (4268/5602 labors). HBsAg or hepatitis C antibodies were positives in 425 (9.9%) of cases (HBsAg positive: 8.48%;Hepatitis C Antibodies positives: 1.50%;both: 0.05%). In HBsAg positive, viral replication and cytolysis were seen respectively in 2.5 % and 18.2%. According with transaminases, serologic markers and viral load, immunotolerance, inactive and immuno active phase were suspected in 0.56%, 80.9% and 1.6% of cases. In hepatitis C antibodies positives persons, any had viral replication but cytolysis was observed in 33.3% (n = 21). HBsAg was significantively (p < 0.00001) higher in exposed occupational enterprise versus non-occupational setting (14.4% vs 7.8%). They were no differences (p = 0.71) about hepatitis C antibodies in the two setting (1.8% vs 1.7%). Conclusion: Prevalence of HBsAg and hepatitis C antibodies was high in occupational setting in hepatitis endemic country. It’s important to screen all of person in these setting with no consideration with blood exposed or not exposed enterprise.
文摘健康企业建设是健康中国建设的细胞基础,是健康城市建设的具体指标之一,探索健康企业建设有效途径和模式是建设过程的重要主题。文章将问题式学习(problem based learning,PBL)教学思路应用于健康企业的创建实践中,提出基于PBL的健康企业创建模式并分析实践效果,认为该模式可以让企业管理者充分参与寻求问题解决措施的过程,转变企业管理者的健康观念、学会健康企业创建理念,起到“授之以渔”的效果,适合在健康企业创建过程中推广应用。