Objective To study the effect of government R&D funding and enterprise R&D input on innovation efficiency of China’s pharmaceutical industry.Methods Based on the inter-provincial panel data of China’s pharma...Objective To study the effect of government R&D funding and enterprise R&D input on innovation efficiency of China’s pharmaceutical industry.Methods Based on the inter-provincial panel data of China’s pharmaceutical industry from 2009 to 2019,the stochastic frontier analysis method was used to study the influence of government R&D funding and enterprise R&D input on the innovation efficiency.Results and Conclusion With 1%increase in government R&D funding,the innovation efficiency of enterprises will increase by 0.122%.When R&D investment increases by 1%,innovation efficiency will increase by 0.169%.Both government R&D funding and enterprise R&D investment promote the innovation efficiency of pharmaceutical enterprises,but the increase of enterprise R&D investment contributes more to the improvement of pharmaceutical innovation efficiency.展开更多
VE organizational field is a management meaning field formed by the mutual action of resources element.It studies leader and partners in VE as a system,and founds the affiliation among them by the relation of resource...VE organizational field is a management meaning field formed by the mutual action of resources element.It studies leader and partners in VE as a system,and founds the affiliation among them by the relation of resources.It describes candidate partner enterprise's inner trait and exterior trait by quality parameter and exterior parameter,then analyzes and evaluates them.It combines the qualitative variable and quantitative variable to evaluate the candidate enterprises.It integrates static and dynamic method to help the VE leader to choose partner,which is good for the whole alliance.展开更多
A successful and effective strategic alliance involves many factors, of which selecting a proper partner is the most important factor to achieve the success of the alliance. In view of the characteristics of strategic...A successful and effective strategic alliance involves many factors, of which selecting a proper partner is the most important factor to achieve the success of the alliance. In view of the characteristics of strategic alliance in high and new technology enterprises and according to the analysis on the standards of partner selecting and the factors of the success of alliance, this paper does some deeper research on the partner selecting and the alliance evaluation process from the perspective of different strategic levels by using a fuzzy comprehensive evaluating method, thus providing a method to select the alliance partner for high and new technology enterprises in China.展开更多
With the deepening of electric power market reform in China,the monopoly edge of the state-owned electric power enterprises will lose.On the basis of the existing post performance salary mechanism,Chinese power enterp...With the deepening of electric power market reform in China,the monopoly edge of the state-owned electric power enterprises will lose.On the basis of the existing post performance salary mechanism,Chinese power enterprises need to optimize the incentive mechanism of R&D staff,to arouse the R&D staff's enthusiasm and creativity,to adapt to the new market competition and further improve market value.Whilst the incentive mechanism optimizing processing needs to consider not only the changing market environment but also the personal and working characteristics of R&D staff.This paper summarizes the characteristics of the current Chinese power enterprises' R&D staff:staff's theory quality is high,but insensitive to the market;they are confronted with heavy workload and diversified job choices;managers can observe their behavior choices or not;besides,the process of R&D is complex and the market reactions of R&D achievements are uncertain.Based on the premise of the above features,two incentive models are established in this paper from the point of view of enterprise managers.One is for the situation when staff's behavior choices can be observed;the other is for the situation when staff's behavior choices cannot be observed.Through solving the model,we analyze the optimization path of electric power enterprises R&D staff incentive mechanism under these conditions:(1) when staff's behavior choices can be observed,managers can pay more to the R&D staff who develop products with higher output value,in order to encourage them to work harder.(2) when staff's behavior choices cannot be observed,managers should take reasonable strategies according to the different situations:a.when R&D staff incentive totally depend on the market value of the R&D achievements,managers should allocate workload rationally according to their different technical levels;b.when the market reactions of R&D results become more precarious,managers need to reduce the incentive intensity which based on the market value and raise their fixed salary level;c.when R&D staff become more risk averse,managers should reduce the incentive intensity which based on the market value and raise their fixed salary level;on the contrary,managers should improve the incentive intensity and reduce the fixed salary level.展开更多
VITEC Distribution is headquartered in Mainz, Germany. On 30 August 2012, the company signed a general distribution agreement with ZTE to sell video conferencing systems in Germany. The agreement allows both companies...VITEC Distribution is headquartered in Mainz, Germany. On 30 August 2012, the company signed a general distribution agreement with ZTE to sell video conferencing systems in Germany. The agreement allows both companies to jointly market video conferencing terminals and servers to enterprises. The German ICT market is one of the largest in Europe (where small and medium-sized enterprises account for over 99.7% of all firms). With its high-definition audio and video solutions, ZTE provides high quality, cost-effective, user-friendly ways for SMEs to start using video conferencing without needing expensive video bridges and superfluous exchange services展开更多
Objective To explore the influence of new drug R&D investment and sales expense on the performance of biomedical enterprises.Methods The financial statements of 76 listed biomedical enterprises for 5 consecutive y...Objective To explore the influence of new drug R&D investment and sales expense on the performance of biomedical enterprises.Methods The financial statements of 76 listed biomedical enterprises for 5 consecutive years were selected,and the data were modeled to study the effect of R&D investment and sales expense on the performance of biomedical enterprises by using financial indicators as tools and statistical methods of multiple linear regression.Results and Conclusion Under the premise that the weak related factors such as enterprise scale,life cycle and asset-liability ratio are set as unrelated variables,the R&D investment intensity of biomedical enterprises is negatively correlated with the current performance,which also shows that the R&D of biomedical enterprises has the characteristics of high risk.Besides,the influence of early R&D investment is delayed.However,the sales expense of leading biomedical enterprises with large scales have higher proportion.Meanwhile the greater sales expense of the same enterprise in different periods,the better the enterprise performance is.Biomedical enterprises should consider their own development stage to develop more patented drugs.Besides,they must formulate plans for allocating reasonable sales personnel and cost expense to ensure that enterprises can obtain better benefits.展开更多
Objective To analyze the relationship between the profitability of pharmaceutical enterprises of different scales and their R&D investment.Methods The data of China’s pharmaceutical manufacturing industry from 19...Objective To analyze the relationship between the profitability of pharmaceutical enterprises of different scales and their R&D investment.Methods The data of China’s pharmaceutical manufacturing industry from 1995 to 2016 were selected to establish a vector auto-regression mode,and then an impulse response function and variance decomposition were used to analyze the data.Results and Conclusion For large-scale pharmaceutical enterprises,1%increase in R&D input will lead to 0.792%increase of their main business profit.For medium-sized enterprises,if their main business profit increases by 1%,their R&D input will increase by 0.965%.Therefore,if their R&D input increases by 1%,their main business profit will increase by 1.036%.The improvement of the profitability of large-scale pharmaceutical enterprises cannot promote the increase of R&D capital investment.But the increase of profitability from medium-sized enterprises can promote the increase of R&D capital investment.As a result,the increase of R&D capital investment of large and medium-sized enterprises can improve corporate profitability.展开更多
Objective To propose a method for identifying cooperation partners and technology opportunities based on technological similarity and technological capability analysis at the critical moment for the survival of small ...Objective To propose a method for identifying cooperation partners and technology opportunities based on technological similarity and technological capability analysis at the critical moment for the survival of small and medium-sized vaccine companies.This method can provide a direction for small and medium-sized enterprises that lack human and financial resources to make full use of its existing technologies.Methods Data analysis was carried out based on patent data.First,through cosine similarity and patent index evaluation,companies with high technological similarity and strong technological capabilities were selected as the target of cooperation.Then evaluation index system of technological development potential was built from three dimensions:technological competitiveness,technological creativity,and potential for industrialization.AHP-CRITIC method was used to determine the comprehensive development potential of each technology.Finally,technology opportunities based on K-means and text mining were identified.Results and Conclusion This method can help small and medium vaccine companies in China to identify technological opportunities and provide directions for product development.展开更多
The key problem in the construction of virtual enterprises (VEs) is how toselect appropriate partners. The negotiation-based approach is proposed to support partner selectionin the construction of VEs. The negotiation...The key problem in the construction of virtual enterprises (VEs) is how toselect appropriate partners. The negotiation-based approach is proposed to support partner selectionin the construction of VEs. The negotiation model is discussed from three main aspectsrespectively, i.e., negotiation protocol, negotiation goal and negotiation decision-making model.And the generic mathematical description of the negotiation model is formally presented. Finally, asimple example is used to validate the approach's availability.展开更多
The problem of risk-based partner selection of virtual enterprise is investigated. By choosing optimal partner for each project task, the project risk is minimized. The risk parameters are expressed in the form of int...The problem of risk-based partner selection of virtual enterprise is investigated. By choosing optimal partner for each project task, the project risk is minimized. The risk parameters are expressed in the form of interval numbers when the precise values are difficult to obtain, and the model is formulated into a 0-1 nonlinear programming with interval coefficients in its objective function. In order to solve the problem, the definition of order relation between interval numbers is given, and the original model is converted into an equivalent crisp bi-objective programming model. Because of the highly constrained nature and multiple objective of the model, a genetic algorithm is proposed to find the set of Pareto or near Pareto optimal solutions. The approach is demonstrated by some numerical examples, and the result shows that the suggested approach has high efficiency and the model has potential to practical applications.展开更多
This paper analyzes the state of the art of partner selection and enumerates the advantage of partner selection based on gray relation analysis comparing to the other algorithms of the partner selection. Furthermore, ...This paper analyzes the state of the art of partner selection and enumerates the advantage of partner selection based on gray relation analysis comparing to the other algorithms of the partner selection. Furthermore, partner selection system based on gray relation for an Agile Virtual Enterprise(AVE) is analyzed and designed based on the definition and characteristics of the AVE. According to J2EE mode, the architecture of the partner selection system is put forward and the system is developed t^ing JSP, EJB and SQL Server. The paper lays emphasis on a gray relational mathematic model, AVE evaluation infrastructure, a core algorithm of partner selection and a multi-layer gray relation selection process.展开更多
Cross-enterprise project is the main implementation form in multi enterprises collaborative production environment. Minimizing the risk of failure and tardiness caused by the uncertainty of partner’s resources in par...Cross-enterprise project is the main implementation form in multi enterprises collaborative production environment. Minimizing the risk of failure and tardiness caused by the uncertainty of partner’s resources in partner selection is the key problem to ensure success in Cross-enterprise project. In this paper, considering the factors and constraints of sub-project processing times, precedence of sub-project and project due date, especially the resource confidence, a 0-1 integer programming model was presented with the objective to minimize the risk of failure and the tardiness of the project. A project scheduling algorithm was designed to search and evaluate selection solutions, and the project scheduling algorithm was embedded into a Tabu search algorithm to solve the model. Simulation experiments and comparisons with other algorithms showed that the proposed approach was possible to find the optimal solution with a faster speed and higher probability.展开更多
In the face of fierce market competition,enterprises must ensure the competitiveness of their products or services through technological innovation.However,the complexity of technology often surpasses the capabilities...In the face of fierce market competition,enterprises must ensure the competitiveness of their products or services through technological innovation.However,the complexity of technology often surpasses the capabilities of individual enterprises,leading them to deepen cooperation with other organizations.The entities within the enterprise innovation ecosystem depend on each other,collaborate closely,and rely on core enterprises to integrate resources,thereby creating system value and enhancing competitiveness.The purpose of this paper is to explore the process of selecting appropriate ecosystem partners.It begins by providing an overview of relevant concepts,characteristics,selection factors,and methods.Subsequently,it analyzes the roles,resources,and synergy evolution of the entities within the ecosystem.An evaluation system encompassing operation,core,synergy,and development capability is then established.This system comprises 16 indicators,including organization scale and reputation,and is accompanied by a hierarchical evaluation model.Finally,the validity of the evaluation system is confirmed through empirical analysis,utilizing the Analytic Hierarchy Process(AHP)and the fuzzy comprehensive evaluation method.展开更多
基金Liaoning Science Public Welfare Research Fund(Soft Science Research Program)in 2022(No.2022JH4/10100040).
文摘Objective To study the effect of government R&D funding and enterprise R&D input on innovation efficiency of China’s pharmaceutical industry.Methods Based on the inter-provincial panel data of China’s pharmaceutical industry from 2009 to 2019,the stochastic frontier analysis method was used to study the influence of government R&D funding and enterprise R&D input on the innovation efficiency.Results and Conclusion With 1%increase in government R&D funding,the innovation efficiency of enterprises will increase by 0.122%.When R&D investment increases by 1%,innovation efficiency will increase by 0.169%.Both government R&D funding and enterprise R&D investment promote the innovation efficiency of pharmaceutical enterprises,but the increase of enterprise R&D investment contributes more to the improvement of pharmaceutical innovation efficiency.
基金Sponsored by the Fund of Shanghai Municipal Education Commission(Grant No.05FZ43).
文摘VE organizational field is a management meaning field formed by the mutual action of resources element.It studies leader and partners in VE as a system,and founds the affiliation among them by the relation of resources.It describes candidate partner enterprise's inner trait and exterior trait by quality parameter and exterior parameter,then analyzes and evaluates them.It combines the qualitative variable and quantitative variable to evaluate the candidate enterprises.It integrates static and dynamic method to help the VE leader to choose partner,which is good for the whole alliance.
文摘A successful and effective strategic alliance involves many factors, of which selecting a proper partner is the most important factor to achieve the success of the alliance. In view of the characteristics of strategic alliance in high and new technology enterprises and according to the analysis on the standards of partner selecting and the factors of the success of alliance, this paper does some deeper research on the partner selecting and the alliance evaluation process from the perspective of different strategic levels by using a fuzzy comprehensive evaluating method, thus providing a method to select the alliance partner for high and new technology enterprises in China.
基金supported by 2016 annual North China Electric Power University undergraduate innovative training program research project(Grant No.20162183)
文摘With the deepening of electric power market reform in China,the monopoly edge of the state-owned electric power enterprises will lose.On the basis of the existing post performance salary mechanism,Chinese power enterprises need to optimize the incentive mechanism of R&D staff,to arouse the R&D staff's enthusiasm and creativity,to adapt to the new market competition and further improve market value.Whilst the incentive mechanism optimizing processing needs to consider not only the changing market environment but also the personal and working characteristics of R&D staff.This paper summarizes the characteristics of the current Chinese power enterprises' R&D staff:staff's theory quality is high,but insensitive to the market;they are confronted with heavy workload and diversified job choices;managers can observe their behavior choices or not;besides,the process of R&D is complex and the market reactions of R&D achievements are uncertain.Based on the premise of the above features,two incentive models are established in this paper from the point of view of enterprise managers.One is for the situation when staff's behavior choices can be observed;the other is for the situation when staff's behavior choices cannot be observed.Through solving the model,we analyze the optimization path of electric power enterprises R&D staff incentive mechanism under these conditions:(1) when staff's behavior choices can be observed,managers can pay more to the R&D staff who develop products with higher output value,in order to encourage them to work harder.(2) when staff's behavior choices cannot be observed,managers should take reasonable strategies according to the different situations:a.when R&D staff incentive totally depend on the market value of the R&D achievements,managers should allocate workload rationally according to their different technical levels;b.when the market reactions of R&D results become more precarious,managers need to reduce the incentive intensity which based on the market value and raise their fixed salary level;c.when R&D staff become more risk averse,managers should reduce the incentive intensity which based on the market value and raise their fixed salary level;on the contrary,managers should improve the incentive intensity and reduce the fixed salary level.
文摘VITEC Distribution is headquartered in Mainz, Germany. On 30 August 2012, the company signed a general distribution agreement with ZTE to sell video conferencing systems in Germany. The agreement allows both companies to jointly market video conferencing terminals and servers to enterprises. The German ICT market is one of the largest in Europe (where small and medium-sized enterprises account for over 99.7% of all firms). With its high-definition audio and video solutions, ZTE provides high quality, cost-effective, user-friendly ways for SMEs to start using video conferencing without needing expensive video bridges and superfluous exchange services
文摘Objective To explore the influence of new drug R&D investment and sales expense on the performance of biomedical enterprises.Methods The financial statements of 76 listed biomedical enterprises for 5 consecutive years were selected,and the data were modeled to study the effect of R&D investment and sales expense on the performance of biomedical enterprises by using financial indicators as tools and statistical methods of multiple linear regression.Results and Conclusion Under the premise that the weak related factors such as enterprise scale,life cycle and asset-liability ratio are set as unrelated variables,the R&D investment intensity of biomedical enterprises is negatively correlated with the current performance,which also shows that the R&D of biomedical enterprises has the characteristics of high risk.Besides,the influence of early R&D investment is delayed.However,the sales expense of leading biomedical enterprises with large scales have higher proportion.Meanwhile the greater sales expense of the same enterprise in different periods,the better the enterprise performance is.Biomedical enterprises should consider their own development stage to develop more patented drugs.Besides,they must formulate plans for allocating reasonable sales personnel and cost expense to ensure that enterprises can obtain better benefits.
基金Research on Innovation and Development Strategy of Pharmaceutical Industry in Liaoning Province(No.2020lslktyb-095).
文摘Objective To analyze the relationship between the profitability of pharmaceutical enterprises of different scales and their R&D investment.Methods The data of China’s pharmaceutical manufacturing industry from 1995 to 2016 were selected to establish a vector auto-regression mode,and then an impulse response function and variance decomposition were used to analyze the data.Results and Conclusion For large-scale pharmaceutical enterprises,1%increase in R&D input will lead to 0.792%increase of their main business profit.For medium-sized enterprises,if their main business profit increases by 1%,their R&D input will increase by 0.965%.Therefore,if their R&D input increases by 1%,their main business profit will increase by 1.036%.The improvement of the profitability of large-scale pharmaceutical enterprises cannot promote the increase of R&D capital investment.But the increase of profitability from medium-sized enterprises can promote the increase of R&D capital investment.As a result,the increase of R&D capital investment of large and medium-sized enterprises can improve corporate profitability.
基金Source of the project:Research Topic on Science and Technology Plan Project of Liaoning Province[2017401021]:“Transformation and Protection of Scientific and Technological Achievements”.
文摘Objective To propose a method for identifying cooperation partners and technology opportunities based on technological similarity and technological capability analysis at the critical moment for the survival of small and medium-sized vaccine companies.This method can provide a direction for small and medium-sized enterprises that lack human and financial resources to make full use of its existing technologies.Methods Data analysis was carried out based on patent data.First,through cosine similarity and patent index evaluation,companies with high technological similarity and strong technological capabilities were selected as the target of cooperation.Then evaluation index system of technological development potential was built from three dimensions:technological competitiveness,technological creativity,and potential for industrialization.AHP-CRITIC method was used to determine the comprehensive development potential of each technology.Finally,technology opportunities based on K-means and text mining were identified.Results and Conclusion This method can help small and medium vaccine companies in China to identify technological opportunities and provide directions for product development.
基金National Natural Science Foundation of China (No. 59990470).
文摘The key problem in the construction of virtual enterprises (VEs) is how toselect appropriate partners. The negotiation-based approach is proposed to support partner selectionin the construction of VEs. The negotiation model is discussed from three main aspectsrespectively, i.e., negotiation protocol, negotiation goal and negotiation decision-making model.And the generic mathematical description of the negotiation model is formally presented. Finally, asimple example is used to validate the approach's availability.
文摘The problem of risk-based partner selection of virtual enterprise is investigated. By choosing optimal partner for each project task, the project risk is minimized. The risk parameters are expressed in the form of interval numbers when the precise values are difficult to obtain, and the model is formulated into a 0-1 nonlinear programming with interval coefficients in its objective function. In order to solve the problem, the definition of order relation between interval numbers is given, and the original model is converted into an equivalent crisp bi-objective programming model. Because of the highly constrained nature and multiple objective of the model, a genetic algorithm is proposed to find the set of Pareto or near Pareto optimal solutions. The approach is demonstrated by some numerical examples, and the result shows that the suggested approach has high efficiency and the model has potential to practical applications.
文摘This paper analyzes the state of the art of partner selection and enumerates the advantage of partner selection based on gray relation analysis comparing to the other algorithms of the partner selection. Furthermore, partner selection system based on gray relation for an Agile Virtual Enterprise(AVE) is analyzed and designed based on the definition and characteristics of the AVE. According to J2EE mode, the architecture of the partner selection system is put forward and the system is developed t^ing JSP, EJB and SQL Server. The paper lays emphasis on a gray relational mathematic model, AVE evaluation infrastructure, a core algorithm of partner selection and a multi-layer gray relation selection process.
文摘Cross-enterprise project is the main implementation form in multi enterprises collaborative production environment. Minimizing the risk of failure and tardiness caused by the uncertainty of partner’s resources in partner selection is the key problem to ensure success in Cross-enterprise project. In this paper, considering the factors and constraints of sub-project processing times, precedence of sub-project and project due date, especially the resource confidence, a 0-1 integer programming model was presented with the objective to minimize the risk of failure and the tardiness of the project. A project scheduling algorithm was designed to search and evaluate selection solutions, and the project scheduling algorithm was embedded into a Tabu search algorithm to solve the model. Simulation experiments and comparisons with other algorithms showed that the proposed approach was possible to find the optimal solution with a faster speed and higher probability.
基金The 2022 Sichuan Tourism Development Research Center General Project“A Study on the Perceived Evaluation and Differences of Tourism Supply between Tourists and Local Residents along the Sichuan Tibet Railway”(Project number:LY22-25)。
文摘In the face of fierce market competition,enterprises must ensure the competitiveness of their products or services through technological innovation.However,the complexity of technology often surpasses the capabilities of individual enterprises,leading them to deepen cooperation with other organizations.The entities within the enterprise innovation ecosystem depend on each other,collaborate closely,and rely on core enterprises to integrate resources,thereby creating system value and enhancing competitiveness.The purpose of this paper is to explore the process of selecting appropriate ecosystem partners.It begins by providing an overview of relevant concepts,characteristics,selection factors,and methods.Subsequently,it analyzes the roles,resources,and synergy evolution of the entities within the ecosystem.An evaluation system encompassing operation,core,synergy,and development capability is then established.This system comprises 16 indicators,including organization scale and reputation,and is accompanied by a hierarchical evaluation model.Finally,the validity of the evaluation system is confirmed through empirical analysis,utilizing the Analytic Hierarchy Process(AHP)and the fuzzy comprehensive evaluation method.