Henoch-Schönlein purpura,the most common childhood vasculitis,is often a self-limiting condition,with resolution within 2-8 weeks.Approximately 20%-40%of the patients develop a renal involvement.[1]Eosinophil cat...Henoch-Schönlein purpura,the most common childhood vasculitis,is often a self-limiting condition,with resolution within 2-8 weeks.Approximately 20%-40%of the patients develop a renal involvement.[1]Eosinophil cationic protein is a secretory ribonuclease which has been associated with cytotoxic,neurotoxic,fibrosis promotion and immuneregulatory functions and has been implicated in various disease conditions.[2]This study was undertaken to clarify a possible role of eosinophil cationic protein in Italian children with Henoch-Schönlein purpura.展开更多
文摘Henoch-Schönlein purpura,the most common childhood vasculitis,is often a self-limiting condition,with resolution within 2-8 weeks.Approximately 20%-40%of the patients develop a renal involvement.[1]Eosinophil cationic protein is a secretory ribonuclease which has been associated with cytotoxic,neurotoxic,fibrosis promotion and immuneregulatory functions and has been implicated in various disease conditions.[2]This study was undertaken to clarify a possible role of eosinophil cationic protein in Italian children with Henoch-Schönlein purpura.
