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基于EPOCHS平台的智能配电网通信系统仿真 被引量:19
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作者 黄飞 王晓茹 +1 位作者 董雪源 王睿 《电力系统自动化》 EI CSCD 北大核心 2013年第11期81-86,共6页
快速、可靠、集成的通信系统是实现智能配电网的关键环节。在当前配电自动化通信系统分析的基础上,对智能配电网通信需求及其业务流量建模,提出了基于IP通信网络的智能配电网通信体系结构。在电力和通信同步仿真(EPOCHS)平台上建立了智... 快速、可靠、集成的通信系统是实现智能配电网的关键环节。在当前配电自动化通信系统分析的基础上,对智能配电网通信需求及其业务流量建模,提出了基于IP通信网络的智能配电网通信体系结构。在电力和通信同步仿真(EPOCHS)平台上建立了智能配电网通信仿真模型,仿真研究了多种数据流业务背景下一种基于通用面向对象变电站事件(GOOSE)的馈线自动化算法通信交互过程,仿真结果表明所提通信体系结构能够满足智能配电网的通信需求。 展开更多
关键词 智能配电网 通信网络 电力和通信同步仿真(epochs)平台 馈线自动化 通用面向对象变电站事件(GOOSE)
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基于EPOCHS平台的IEC 61850采样值传输仿真 被引量:11
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作者 丁力 王晓茹 童晓阳 《电力系统自动化》 EI CSCD 北大核心 2008年第20期67-72,共6页
采样值传输是IEC61850变电站自动化系统过程层与间隔层之间通信的主要部分。在电力和通信系统同步仿真(EPOCHS)平台上提出IEC61850变电站通信仿真框架,针对具体变电站构建IEC61850通信模型。在NS2中添加虚拟局域网(VLAN)IEEE802.1Q协议... 采样值传输是IEC61850变电站自动化系统过程层与间隔层之间通信的主要部分。在电力和通信系统同步仿真(EPOCHS)平台上提出IEC61850变电站通信仿真框架,针对具体变电站构建IEC61850通信模型。在NS2中添加虚拟局域网(VLAN)IEEE802.1Q协议代码,实现VLAN多播报文的仿真。对交换式以太网和共享式以太网、接收不同数目合并单元采样值报文的保护设备进行了比较。结果表明:100Mbit/s交换式以太网完全满足标准要求,而100Mbit/s共享式以太网采样值报文时延和时延抖动较大,导致工频保护测量值波形畸变;接收多个采样值报文的保护设备存在链路瓶颈问题,对此提出了多通信插件的解决方案。 展开更多
关键词 IEC 61850 采样值传输 虚拟局域网(VLAN)多播 电力和通信系统同步仿真(epochs)平台 NS2
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基于EPOCHS平台的监控网与GOOSE网合一的网络仿真分析 被引量:1
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作者 王义军 李晨曦 +1 位作者 秦思远 王喜 《电测与仪表》 北大核心 2015年第17期44-47,共4页
通用面向对象的变电站事件(GOOSE)是IEC 61850标准中用于满足变电站自动化系统快速报文需求的机制。针对监控网与GOOSE网合一的网络结构,运用电力通信同步仿真平台(EPOCHS)进行通信网络动态仿真。通过对GOOSE及采样值(SAV)实时性的仿真... 通用面向对象的变电站事件(GOOSE)是IEC 61850标准中用于满足变电站自动化系统快速报文需求的机制。针对监控网与GOOSE网合一的网络结构,运用电力通信同步仿真平台(EPOCHS)进行通信网络动态仿真。通过对GOOSE及采样值(SAV)实时性的仿真分析,其结果为报文优先级、网络带宽及组网的创新拓展提供了依据。 展开更多
关键词 GOOSE MMS epochs SAV 实时性
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基于EPOCHS的数字化电力通信光传输网络的优化改造 被引量:1
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作者 卢嘉斌 《数字技术与应用》 2018年第11期36-37,共2页
将EPOCHS仿真软件应用电力通信网络中,能够有效克服存在的弊端,使电力通信网络效果得到显著增强。基于此,本文将对EPOCHS在电力传输网络中的优化仿真实验进行分析与研究。
关键词 epochs仿真软件 电力通信 数字化
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Formation of Glaciation Epochs
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作者 Sanghee Shin George V. Chilingar +1 位作者 Oleg Sorokhtin Nikolai O. Sorokhtin 《Journal of Environmental Protection》 2013年第6期516-521,共6页
The effect of Earth precession angle on a climate is presented here. It is shown that the glaciation epochs occurred only when the precession angle was low. After the continental glaciation formed in the Northern hemi... The effect of Earth precession angle on a climate is presented here. It is shown that the glaciation epochs occurred only when the precession angle was low. After the continental glaciation formed in the Northern hemisphere, Earth’s spherecal symmetry was disrupted and its precession angle increased drastically. As a result, a drastic and rapid climate warm-up occurred, the glaciers melted down and an interglacial stadial1 began. Subsequently, affected by the Lunar-Solar gravity pull on the Earth’s equatorial swelling, the precession angle gradually decreased and a new cooling-down phase occurred. As a result, there was nonlinear oscillation of Earth’s climate with periods on the order of 100 - 120 MY. 展开更多
关键词 Earth’s PRECESSION GLACIATION epochs CLIMATE Evolution CLIMATE Change GLOBAL WARMING GLOBAL COOLING
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GOLD METALLOGENETIC EPOCHS IN GEODOME STRUCTURES
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《Geotectonica et Metallogenia》 1994年第Z2期91-93,共3页
关键词 GOLD METALLOGENETIC epochs IN GEODOME STRUCTURES
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Reduced Dynamic Orbit Determination Using Differenced Phase in Adjacent Epochs for Spaceborne Dual-frequency GPS 被引量:4
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作者 GU Defeng YI Dongyun 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2011年第6期789-796,共8页
We study on reduced dynamic orbit determination using differenced phase in adjacent epochs for spacebome dual-frequency GPS. This method not only overcomes the shortcomings that the epoch-difference kinematic method c... We study on reduced dynamic orbit determination using differenced phase in adjacent epochs for spacebome dual-frequency GPS. This method not only overcomes the shortcomings that the epoch-difference kinematic method cannot be used when observation geometry is poor or observations are insufficient, but also avoids solving the ambiguity in the zero-difference reduced dynamic method. As the epoch-difference method is not sensitive to the impact of phase cycle slips, it can lower the difficulty of slip detection in phase observation preprocessing. In the solution strategies, we solve the high-dimensional matrix computation problems by decomposing the long observation arc into a number of short arcs. By gravity recovery and climate experiment (GRACE) satellite orbit determination and compared with GeoForschungsZentrum (GFZ) post science orbit, for epoch-difference reduced dynamic method, the root mean squares (RMSs) of radial, transverse and normal components are 1.92 cm, 3.83 cm and 3.80 cm, and the RMS in three dimensions is 5.76 cm. The solution's accuracy is comparable to the zero-difference reduced dynamic method. 展开更多
关键词 dual-frequency GPS phase difference in adjacent epochs SATELLITE reduced dynamic orbit determination
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精准给药策略联合预见性护理在接受R⁃EPOCH方案治疗的非霍奇金淋巴瘤病人中的应用
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作者 牛润花 杨佳 +1 位作者 赵新娜 郝晓丽 《护理研究》 北大核心 2024年第2期349-353,共5页
目的:探讨精准给药策略联合预见性护理在接受R⁃EPOCH方案治疗的非霍奇金淋巴瘤病人中的应用效果。方法:采用便利抽样法,选取2021年1月—2022年12月山西省某三级甲等医院血液科住院并采用R⁃EPOCH方案治疗的非霍奇金淋巴瘤病人为研究对象,... 目的:探讨精准给药策略联合预见性护理在接受R⁃EPOCH方案治疗的非霍奇金淋巴瘤病人中的应用效果。方法:采用便利抽样法,选取2021年1月—2022年12月山西省某三级甲等医院血液科住院并采用R⁃EPOCH方案治疗的非霍奇金淋巴瘤病人为研究对象,将2021年住院的70例病人作为对照组,将2022年住院的73例病人作为观察组。对照组实施常规护理,观察组实施精准给药策略联合预见性护理。比较两组护士实际给药时间、病人焦虑情况及生命质量。结果:研究过程中对照组有2例病人失访,观察组有3例病人失访,最终对照组68例病人完成研究,观察组70例病人完成研究。观察组护士实际给药总时间为(96.16±9.45)h,短于对照组[(99.77±10.22)h],差异有统计学意义(P<0.05),且观察组护士实际给药总时间更接近指南要求(持续输注96 h)。随着时间变化,非霍奇金淋巴瘤病人汉密尔顿焦虑量表(HAMA)得分有变化(P<0.05),不同组别的非霍奇金淋巴瘤病人HAMA得分不同(P<0.05),干预时间与干预方法间存在交互效应(P<0.05)。干预后,观察组病人癌症病人生命质量测定量表(FACT⁃G)总体及各维度得分均高于对照组,差异均有统计学意义(P<0.05)。结论:将精准给药策略联合预见性护理应用于接受R⁃EPOCH方案治疗的非霍奇金淋巴瘤病人,可以提高病人给药时间的准确性,改善病人焦虑状况,提高病人生活质量。 展开更多
关键词 非霍奇金淋巴瘤 R⁃EPOCH方案 精准给药 预见性护理 化疗 护理
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An Exploration of the Three Dimensions and Epochal Strengths of Building a Human Community With a Shared Future
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作者 Jiang Ruibing Liu Zongling 《Contemporary Social Sciences》 2024年第3期120-138,共19页
The idea of a human community with a shared future was proposed by the Communist Party of China(CPC)Central Committee with Comrade Xi Jinping at its core for the future development of human beings to face up to the mo... The idea of a human community with a shared future was proposed by the Communist Party of China(CPC)Central Committee with Comrade Xi Jinping at its core for the future development of human beings to face up to the most important question in today's world:“What is happening to the world and what should we do?”It profoundly answers the question of the world,history,and the times.The theory of a human community with a shared future is an innovative theory with a multidimensional formation logic that guides humanity toward continually seeking common interests and values.This paper dives into the profound motivations behind building a human community with a shared future from historical,cultural,and practical dimensions and analyzes its epochal value from both domestic and international perspectives.This not only helps exert China's role in the international community,contributing Chinese strength to the construction of a peaceful,stable,and prosperous human society,but also enhances the influence of the idea of a human community with a shared future in the international community,accelerating the building of a human community with a shared future that considers the legitimate concerns of all countries,and aiding in solving the crises facing the world. 展开更多
关键词 a human community with a shared future historical dimension cultural dimension practical dimension epochal strength
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广域后备保护多代理系统的仿真建模与实现 被引量:11
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作者 童晓阳 王晓茹 +1 位作者 Kenneth Hopkinson 汤俊 《中国电机工程学报》 EI CSCD 北大核心 2008年第19期111-117,共7页
针对广域后备保护多代理系统分布式协作的特点,为广域后备保护代理构造了环境感知、情景感知、综合决策等智能模块和接口,设计了多代理系统的容错性处理措施。EPOCHS是将电力系统电磁暂态仿真软件EMTDC/PSCAD、机电动态仿真软件PSLF、... 针对广域后备保护多代理系统分布式协作的特点,为广域后备保护代理构造了环境感知、情景感知、综合决策等智能模块和接口,设计了多代理系统的容错性处理措施。EPOCHS是将电力系统电磁暂态仿真软件EMTDC/PSCAD、机电动态仿真软件PSLF、网络通信仿真软件NS2、Agent集成的电力和通信同步仿真环境,将保护代理映射到EPOCHS予以仿真设计和实现,构造了电网的EMDTC/PSCAD模型和SDH通信网络的NS2仿真模型。通过仿真系统可观察保护代理的内部活动和多代理间的交互过程,从而评价广域保护算法及策略。通过3个仿真实例证明广域后备保护多代理仿真系统的代理设计是正确的。仿真试验能够有效地检验在电力系统故障、保护代理失效、断路器失灵等多种情景下多代理推演带来的整体性能。 展开更多
关键词 广域后备保护 多代理系统 仿真设计 epochs
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Modification of the Lagrange-Jacobi Equation and Its Application
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作者 Chingis Omarov Gulnara Omarova 《World Journal of Mechanics》 2023年第6期127-134,共8页
The Lagrange-Jacobi equation is one of the significant tools for the qualitative analysis of the n-body problem. In this paper, we present the modified Lagrange-Jacobi equation by introducing a new formal parameter of... The Lagrange-Jacobi equation is one of the significant tools for the qualitative analysis of the n-body problem. In this paper, we present the modified Lagrange-Jacobi equation by introducing a new formal parameter of n-body problem and propose its application to the dynamical study of clusters of galaxies which are large-scale structures of Universe. We put forward and study a new dynamical problem which is related to the stage of relaxation of observed stationary clusters of galaxies which are considered as a non-equilibrium systems of point masses. We also received the analytical form of the potential energy of such galaxy clusters. One of the applications of this analytical form is the analytical relation between the time  of setting up the virial equilibrium in relaxing clusters of galaxies and the cosmological epoch T. 展开更多
关键词 Celestial Mechanics Large-Scale Structure of Universe GALAXIES CLUSTERS Cosmological Epoch
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Phase-Transitions at High, Very High, and Very Low Temperatures upon Nano-Indentations: Onset Forces and Transition Energies
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作者 Gerd Kaupp 《Advances in Materials Physics and Chemistry》 2023年第6期101-120,共20页
This paper describes the phase-transition energies from published loading curves on the basis of the physically deduced F<sub>N</sub> = k-h<sup>3/2</sup> law that does not violate the energy la... This paper describes the phase-transition energies from published loading curves on the basis of the physically deduced F<sub>N</sub> = k-h<sup>3/2</sup> law that does not violate the energy law by assuming h<sup>2</sup> instead, as still do ISO-ASTM 14,577 standards. This law is valid for all materials and all “one-point indentation” temperatures. It detects initial surface effects and phase-transition kink-unsteadiness. Why is that important? The mechanically induced phase-transitions form polymorph interfaces with increased risk of crash nucleation for example at the pickle forks of airliners. After our published crashing risk, as nucleated within microscopic polymorph-interfaces via pre-cracks, had finally appeared (we presented microscopic images (5000×) from a model system), 550 airliners were all at once grounded for 18 months due to such microscopic pre-cracks at their pickle forks (connection device for wing to body). These pre-cracks at phase-transition interfaces were previously not complained at the (semi)yearlycheckups of all airliners. But materials with higher compliance against phase- transitions must be developed for everybody’s safety, most easily by checking with nanoindentations, using their physically correct analyses. Unfortunately, non-physical analyses, as based on the after all incredible exponent 2 on h for the F<sub>N</sub> versus h loading curve are still enforced by ISO-ASTM standards that cannot detect phase-transitions. These standards propagate that all of the force, as applied to the penetrating cone or pyramid shall be used for the depth formation, but not also in part for the pressure to the indenter environment. However, the remaining part of pressure (that was not consumed for migrations, etc.) is always used for the elastic modulus detection routine. That severely violates the energy-law! Furthermore, the now physically analyzed published loading curves contain the phase-transition onsets and energies information, because these old-fashioned authors innocently (?) published (of course correct) experimental loading curves. These follow as ever the physically deduced F<sub>N</sub> = k-h<sup>3/2</sup> relation that does not violate the energy law. Nevertheless, the old-fashioned authors stubbornly assume h<sup>2</sup>instead of h<sup>3/2</sup> as still do ISO-ASTM 14,577 standards according to an Oliver-Pharr publication of 1992 and textbooks. The present work contributes to understanding the temperature dependence of phase-transitions under mechanical load, not only for aviation and space flights, which is important. The physical calculations use exclusively regressions and pure algebra (no iterations, no fittings, and no simulations) in a series of straightforward steps by correcting for unavoidable initial effects from the axis cuts of the linear branches from the above equation exhibiting sharp kink unsteadiness at the onset of phase transitions. The test loading curves are from Molybdenum and Al 7075 alloy. The valid published loading curves strictly follow the F<sub>N</sub> = k-h<sup>3/2</sup> relation. Full applied work, conversion work, and conversion work per depth unit show reliable overall comparable order of magnitude values at temperature increase by 150°C (Al 7075) and 980°C (Mo) when also considering different physical hardnesses and penetration depths. It turns out how much the normalized endothermic phase-transition energy decreases upon temperature increase. For the only known 1000°C indentation we provide reason that the presented loading curves changes are only to a minor degree caused by the thermal expansion. The results with Al 7075 up to 170°C are successfully compared. Al 7075 alloy is also checked by indentation with liquid nitrogen cooling (77 K). It gives two endothermic and one very prominent exothermic phase transition with particularly high normalized phase-transition energy. This indentation loading curve at liquid nitrogen temperature reveals epochal novelties. The energy requiring endothermic phase transitions (already seen at 20°C and above) at 77 K is shortly after the start of the second polymorph (sharply at 19.53 N loading force) followed by a strongly exothermic phase-transition by producing (that is losing) energy-content. Both processes at 77 K are totally unexpected. The produced energy per depth unit is much higher energy than the one required for the previous endothermic conversions. This exothermic phase-transition profits from the inability to provide further energy for the formation of the third polymorph as endothermic obtained at 70°C and above. That is only possible because the very cold crystal can no longer support endothermic events but supports exothermic ones. Both endothermic and exothermic phase-transitions at 77 K under load are unprecedented and were not expected before. While the energetic support at 77 K for endothermic processes under mechanical load is unusual but still understandable (there are also further means to produce lower temperatures). But strongly exothermicphase-transition under mechanical load for the production of new modification with negative energy content (less than the energy content of the ambient polymorph) at very low temperature is an epochal event here on earth. It leads to new global thinking and promises important new applications. The energy content of strongly exothermic transformed material is less than the thermodynamic standard zero energy-content on earth. And it can only be reached when there is no possibility left to produce an endothermic phase-transition. Such less than zero-energy-content materials should be isolated, using appropriate equipment. Their properties must be investigated by chemists, crystallographers, and physicists for cosmological reasons. It could be that such materials will require cooling despite their low energy content (higher stability!) and not survive at ambient temperatures and pressures on earth, but only because we do not know of such negative-energy-content materials with our arbitrary thermodynamic standard zeros on earth. At first one will have to study how far we can go up with temperature for keeping them stable. Thus, the apparently never before considered unprecedented result opens up new thinking for the search of new polymorphs that can, of course, not be reached by heating. Various further applications including cosmology and space flight explorations are profiting from it. 展开更多
关键词 Aluminum Alloy Aviation Cosmology Epochal News High and Liquid Nitrogen Temperature Indentations Negative-Energy-Content Polymorph Molybdenum Phase-Transition-Energy
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剂量调整的EPOCH方案治疗初治血管免疫母T细胞淋巴瘤的前瞻性研究 被引量:6
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作者 仲凯励 苏航 +6 位作者 肖秀斌 刘静 鲁云 陈喜林 达永 路春蕾 张伟京 《中国肿瘤临床》 CAS CSCD 北大核心 2014年第19期1229-1233,共5页
目的:前瞻性研究剂量调整的EPOCH方案对初治血管免疫母T细胞淋巴瘤(AITL)患者的疗效及不良反应。方法:选择2008年9月至2012年9月中国军事医学科学院附属307医院确诊的初治AITL患者9例。全组患者均接受剂量调整的EPOCH方案一线化疗... 目的:前瞻性研究剂量调整的EPOCH方案对初治血管免疫母T细胞淋巴瘤(AITL)患者的疗效及不良反应。方法:选择2008年9月至2012年9月中国军事医学科学院附属307医院确诊的初治AITL患者9例。全组患者均接受剂量调整的EPOCH方案一线化疗。结果:全组患者发病中位年龄54岁,男∶女为2∶1,88.9%为Ann-Arbor stageⅢ~Ⅳ期,77.8%合并B症状。初诊时伴有贫血的患者占66.7%,LDH或β2微球蛋白升高占55.6%。EPOCH方案近期疗效CR率22.2%,总反应率66.7%。中位随访20个月,4年PFS和OS分别为11.1%和33.3%,中位生存时间19个月。EPOCH方案化疗主要不良反应为血液学毒性,3~4度粒细胞减少和血小板减少分别为77.8%和33.3%,44.4%的患者出现粒细胞缺乏伴发热。结论:剂量调整的EPOCH方案一线治疗AITL患者较传统CHOP方案未见明显生存获益。主要不良反应为血液学毒性,并可以耐受。 展开更多
关键词 血管免疫母T细胞淋巴瘤 EPOCH方案 初治 化疗
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GELOX与EPOCH方案化疗序贯放疗一线治疗ⅠE/ⅡE期结外NK/T细胞淋巴瘤的疗效比较 被引量:5
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作者 吴肖志军 王华 +3 位作者 王科峰 陈晓勤 夏忠军 李苏 《广东医学》 CAS CSCD 北大核心 2013年第6期864-866,共3页
目的比较GELOX(吉西他滨、奥沙利铂、左旋门冬酰胺酶)与EPOCH方案(依托泊苷、泼尼松、长春新碱、环磷酰胺、阿霉素)化疗序贯放疗一线治疗ⅠE/ⅡE期结外NK/T细胞淋巴瘤的近期疗效、远期生存及安全性。方法共计63例初诊患者经影像学检查... 目的比较GELOX(吉西他滨、奥沙利铂、左旋门冬酰胺酶)与EPOCH方案(依托泊苷、泼尼松、长春新碱、环磷酰胺、阿霉素)化疗序贯放疗一线治疗ⅠE/ⅡE期结外NK/T细胞淋巴瘤的近期疗效、远期生存及安全性。方法共计63例初诊患者经影像学检查、病理学诊断确诊为ⅠE/ⅡE期结外NK/T细胞淋巴瘤,其中27例接受GELOX化疗,36例接受EPOCH化疗,化疗完成后行侵犯野放射治疗。结果化疗后GELOX组完全缓解(CR)率为70.4%,总体有效率(ORR)为85.2%,均显著高于EPOCH组的41.7%与61.1%(PCR=0.024,PORR=0.036);两组有效率差异无统计学意义(P>0.05)。GELOX组的远期生存则表现出较明显的优势:GELOX组与EPOCH组3年无进展生存率分别为77.8%和47.6%,差异有统计学意义(P=0.011);3年总生存率分别为88.5%、56.6%,差异有统计学意义(P=0.012)。EPOCH组的血液学毒性更严重,GELOX组中15例(55.6%)患者出现纤维蛋白原下降,但均较轻微且无严重不良事件,其余毒性均较轻微。结论与EPOCH方案相比,GELOX方案具有较好的近期疗效,提高了远期生存,且不良反应较轻,安全性更高。 展开更多
关键词 结外NK T细胞淋巴瘤 GELOX EPOCH 化学治疗 近期疗效 远期生存
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EPOCH方案和CHOP方案一线治疗非特殊性外周T细胞淋巴瘤回顾性临床对照研究 被引量:5
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作者 王轶楠 刘卫东 +4 位作者 马守东 肖建波 李海丽 王志武 岳海淑 《现代肿瘤医学》 CAS 2014年第2期420-422,共3页
目的:比较EPOCH方案和CHOP方案一线治疗非特殊性外周T细胞淋巴瘤(PTCL-U)的疗效及不良反应。方法:A组:2008年1月至2010年4月,24例经病理确诊的PTCL-U患者,采用EPOCH方案化疗:足叶已甙50mg/(m2·d),长春新碱0.4mg/(m2·d),表阿霉... 目的:比较EPOCH方案和CHOP方案一线治疗非特殊性外周T细胞淋巴瘤(PTCL-U)的疗效及不良反应。方法:A组:2008年1月至2010年4月,24例经病理确诊的PTCL-U患者,采用EPOCH方案化疗:足叶已甙50mg/(m2·d),长春新碱0.4mg/(m2·d),表阿霉素15mg/(m2·d),上述三种药物持续静脉滴注96h,环磷酰胺750mg/m2,静脉滴注,d5;强的松60mg/(m2·d),口服,d1-5。每3周为1周期。B组:2005年1月至2007年4月PTCL-U患者35例,采用CHOP方案化疗:环磷酰胺750mg/m2,静脉滴注,d1,表阿霉素75mg/m2,静脉滴注,d1,长春新碱1.4mg/m2,静脉滴注,d1,强的松60mg/(m2·d),口服,d1-5,每3周为1周期。对两组的近期疗效、疾病进展时间、不良反应进行分析比较。结果:A组和B组的完全缓解效率分别为66.7%(16/24)和40.0%(14/35),有显著性差异(P=0.0441),有效率分别为79.2%(19/24)和65.7%(23/35),无显著差异(P=0.2624)。A组和B组的中位疾病进展时间12.0月(1-27月)、10月(1-28月)(P=0.2045)。主要不良反应白细胞减少、神经毒性、脱发、心脏毒性等指标均无显著性差异(P>0.05)。轻度口腔炎的发生率A组高于B组:24.8%∶13%(P<0.05)。结论:一线治疗PTCL-U,EPOCH方案近期疗效较CHOP方案具有一定的优势,不良反应相近,耐受性好。 展开更多
关键词 外周T细胞淋巴瘤 化学治疗 EPOCH方案 CHOP方案 药物持续静脉滴注
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Hyper-CVAD/MA与EPOCH方案治疗侵袭性非霍奇金淋巴瘤临床效果比较 被引量:4
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作者 朱太岗 董毅 +2 位作者 李月红 张飞虎 汤继春 《安徽医学》 2014年第6期770-773,共4页
目的比较Hyper-CVAD/MA与EPOCH两种方案治疗侵袭性非霍奇金淋巴瘤的临床效果。方法 35例侵袭性非霍奇金淋巴瘤初治患者随机分为Hyper-CVAD/MA组(17例)与EPOCH组(18例),按各自的方案给药,评估其疗效和不良反应。结果 Hyper-CVAD/MA组总... 目的比较Hyper-CVAD/MA与EPOCH两种方案治疗侵袭性非霍奇金淋巴瘤的临床效果。方法 35例侵袭性非霍奇金淋巴瘤初治患者随机分为Hyper-CVAD/MA组(17例)与EPOCH组(18例),按各自的方案给药,评估其疗效和不良反应。结果 Hyper-CVAD/MA组总有效率为64.71%,EPOCH组总有效率为72.22%。两种方案治疗的患者均出现不同程度骨髓抑制,消化道反应、脱发、神经毒性、黏膜炎等,两种方案的不良反应差异无统计学意义(P>0.05)。结论 Hyper-CVAD/MA与EPOCH两种方案治疗侵袭性非霍奇金淋巴瘤的临床效果与不良反应相当,两者均为治疗侵袭性淋巴瘤的合理化疗方案。 展开更多
关键词 非霍奇金淋巴瘤 Hyper-CVAD/MA方案 EPOCH方案 临床效果 不良反应
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EPOCH方案治疗非霍奇金淋巴瘤的观察和护理 被引量:6
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作者 孙文瑞 沈志坚 朱美仙 《温州医学院学报》 CAS 2006年第2期177-178,共2页
关键词 EPOCH方案 非霍奇金淋巴瘤 护理
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EPOCH方案治疗联合针对性护理对非霍奇金淋巴瘤化疗患者的影响 被引量:8
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作者 陈丽珍 黄再芬 徐丽珍 《齐鲁护理杂志》 2019年第23期55-57,共3页
目的:探讨EPOCH方案治疗联合针对性护理对非霍奇金淋巴瘤(NHL)化疗患者的影响。方法:选取2018年1月1日~6月30日收治的17例NHL患者为对照组,采用常规护理;选取2018年7月1日~12月31日收治的18例NHL患者为观察组,采用针对性护理。两组均给... 目的:探讨EPOCH方案治疗联合针对性护理对非霍奇金淋巴瘤(NHL)化疗患者的影响。方法:选取2018年1月1日~6月30日收治的17例NHL患者为对照组,采用常规护理;选取2018年7月1日~12月31日收治的18例NHL患者为观察组,采用针对性护理。两组均给予EPOCH方案化疗。比较两组口腔、肛周、中心静脉导管感染的发生情况及生活质量[采用健康调查简表(SF-36)]。结果:观察组口腔、肛周、中心静脉导管感染发生率低于对照组(P<0.05);观察组SF-36中生理功能、精神状态、社会功能、一般健康评分均高于对照组(P<0.01,P<0.05)。结论:对NHL化疗患者接受EPOCH方案进行治疗时,给予针对性护理,可降低患者口腔、肛周、中心静脉导管感染等并发症发生率,有效提高其生活质量。 展开更多
关键词 非霍奇金淋巴瘤 EPOCH 化疗 感染 针对性护理
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不同时机抗HIV治疗联合EPOCH化疗对艾滋病相关淋巴瘤患者免疫功能的影响 被引量:3
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作者 阮光靖 谢志满 +1 位作者 董文艺 何华伟 《广西医学》 CAS 2019年第15期1977-1979,1982,共4页
目的探讨EPOCH化疗联合抗HIV治疗的时机对艾滋病相关淋巴瘤患者免疫功能的影响及其安全性。方法选择90例艾滋病相关淋巴瘤患者为研究对象,按不同抗HIV病毒治疗时机分为A组(化疗前1周内开始抗病毒治疗)、B组(化疗完成一半后的1周内开始... 目的探讨EPOCH化疗联合抗HIV治疗的时机对艾滋病相关淋巴瘤患者免疫功能的影响及其安全性。方法选择90例艾滋病相关淋巴瘤患者为研究对象,按不同抗HIV病毒治疗时机分为A组(化疗前1周内开始抗病毒治疗)、B组(化疗完成一半后的1周内开始抗病毒治疗)、C组(化疗结束后开始抗病毒治疗),各30例。比较三组患者治疗后的免疫水平及不良反应发生率。结果治疗后,A、B两组患者的CD4^+T淋巴细胞比例与治疗前比较差异均无统计学意义(均P>0.05),C组治疗后的CD4^+T淋巴细胞比例较治疗前降低,且低于A组和B组(均P<0.05)。治疗后,A、B、C3组的CD8^+T淋巴细胞比例均较治疗前升高,CD4^+/CD8^+比值均较治疗前下降(均P<0.05),但3组治疗后的CD8^+T淋巴细胞比例、CD4^+/CD8^+比值比较,差异均无统计学意义(均P>0.05)。A组患者神经系统症状、胃肠道反应症状发生率高于B组及C组(均P<0.05),A、B、C3组感染、肝肾功能异常、骨髓抑制、血压升高等不良反应发生率比较差异均无统计学意义(均P>0.05)。结论在艾滋病相关淋巴瘤患者行EPOCH化疗方案一半后的1周内开始进行抗HIV病毒治疗,对机体的免疫功能影响较小,不良反应发生较少,值得临床推广应用。 展开更多
关键词 艾滋病相关淋巴瘤 EPOCH化疗 抗HIV病毒 免疫功能 安全性
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EPOCH方案治疗复发性B细胞非霍奇金淋巴瘤的临床护理 被引量:2
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作者 向丽娥 鲁明骞 +3 位作者 徐光川 房民琴 田玉凤 王毅 《现代肿瘤医学》 CAS 2007年第12期1887-1888,共2页
目的:探讨EPOCH方案治疗复发性非霍奇金淋巴瘤的治疗与护理方法。方法:复发非霍奇金淋巴瘤患者30例,行EPOCH方案化疗,在常规护理的同时,加强心理护理和化疗毒副反应的护理。结果:30例患者CR9例(30%),PR10例(33.3%),总有效率63.3%(19/30... 目的:探讨EPOCH方案治疗复发性非霍奇金淋巴瘤的治疗与护理方法。方法:复发非霍奇金淋巴瘤患者30例,行EPOCH方案化疗,在常规护理的同时,加强心理护理和化疗毒副反应的护理。结果:30例患者CR9例(30%),PR10例(33.3%),总有效率63.3%(19/30)。结论:EPOCH方案是治疗复发性B细胞非霍奇金淋巴瘤的有效解救化疗方案,患者耐受性好,毒副反应小。心理护理减少了患者对化疗的恐惧感,化疗后的护理使治疗能顺利完成,增强了治疗效果。 展开更多
关键词 非霍奇金淋巴瘤 EPOCH方案 护理
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