Neste公司与领先的实验室设备制造商和供应商Eppendorf公司合作,共同开发使用可再生原料制成的实验室产品。双方通过战略合作使建立可再生塑料试验耗材(Eppendorf耗材BioBased)的新生产线成为可能。耗材(例如管子)由100%可再生原料(例...Neste公司与领先的实验室设备制造商和供应商Eppendorf公司合作,共同开发使用可再生原料制成的实验室产品。双方通过战略合作使建立可再生塑料试验耗材(Eppendorf耗材BioBased)的新生产线成为可能。耗材(例如管子)由100%可再生原料(例如使用过的食用油)生产,采用Neste RE TM技术制造。因此,对于试图通过取代价值链中的石油来减少碳足迹的实验室来说,选择可再生耗材代表选择一种可持续的发展路径。新生产线首批产品的推出将为生命科学行业向更可持续的未来转型做出重大贡献。展开更多
Objectives. The aim of this study was to investigate the expression of the pro apoptotic protein Apaf-1 in cervical cancers. Moreover, we studied its correlat ion to intratumoral pO2 and to clinico-pathological parame...Objectives. The aim of this study was to investigate the expression of the pro apoptotic protein Apaf-1 in cervical cancers. Moreover, we studied its correlat ion to intratumoral pO2 and to clinico-pathological parameters. Methods. 86 pat ients with cervical cancer were subjected to intratumoral pO2 measurement with t he Eppendorf electrode. From these patients, cervical cancer tissue was used for immunohistochemistry with an anti-Apaf-1 antibody. Results. Apaf-1 is expres sed in cervical cancer. Cervical cancers with strong or moderate Apaf-1 express ion had significantly less lymph node metastases at time of surgery than tumors with weak or negative Apaf-1 expression (P = 0.022). There was no significant c orrelation between Apaf-1 expression and intratumoral pO2,pT stage, FIGO stage, lymphovascular space involvement, and grade. Conclusions. Loss of Apaf-1 expre ssion may represent a marker of aggressive tumor behavior since it correlates si gnificantly with the occurrence of lymph node metastasis in cervical cancer.展开更多
文摘Neste公司与领先的实验室设备制造商和供应商Eppendorf公司合作,共同开发使用可再生原料制成的实验室产品。双方通过战略合作使建立可再生塑料试验耗材(Eppendorf耗材BioBased)的新生产线成为可能。耗材(例如管子)由100%可再生原料(例如使用过的食用油)生产,采用Neste RE TM技术制造。因此,对于试图通过取代价值链中的石油来减少碳足迹的实验室来说,选择可再生耗材代表选择一种可持续的发展路径。新生产线首批产品的推出将为生命科学行业向更可持续的未来转型做出重大贡献。
文摘Objectives. The aim of this study was to investigate the expression of the pro apoptotic protein Apaf-1 in cervical cancers. Moreover, we studied its correlat ion to intratumoral pO2 and to clinico-pathological parameters. Methods. 86 pat ients with cervical cancer were subjected to intratumoral pO2 measurement with t he Eppendorf electrode. From these patients, cervical cancer tissue was used for immunohistochemistry with an anti-Apaf-1 antibody. Results. Apaf-1 is expres sed in cervical cancer. Cervical cancers with strong or moderate Apaf-1 express ion had significantly less lymph node metastases at time of surgery than tumors with weak or negative Apaf-1 expression (P = 0.022). There was no significant c orrelation between Apaf-1 expression and intratumoral pO2,pT stage, FIGO stage, lymphovascular space involvement, and grade. Conclusions. Loss of Apaf-1 expre ssion may represent a marker of aggressive tumor behavior since it correlates si gnificantly with the occurrence of lymph node metastasis in cervical cancer.
