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Evaluation of Compatibilizers for Improving Compatibility between Waste Vegetable Oil and Aged Asphalt
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作者 WANG Yanghui DING Yongjie +3 位作者 LI Danli CAO Zhilong SUN Guoqiang MEI Zijun 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第5期1278-1286,共9页
Modifying agents 2,2-Bis(4-glycidyloxyphenyl)propane(2BPE)and dibutyl phthalate(DBP)were selected to enhance the compatibility.By using molecular simulation software(Materials Studio,MS),nine systems were constructed,... Modifying agents 2,2-Bis(4-glycidyloxyphenyl)propane(2BPE)and dibutyl phthalate(DBP)were selected to enhance the compatibility.By using molecular simulation software(Materials Studio,MS),nine systems were constructed,including molecular models of aged asphalt and WVO monomers with 2BPE and/or DBP.The solubility parameters,Flory-Huggins parameters,and interaction energies of these systems were calculated to determine the impact of 2BPE and DBP on the compatibility of WVO and aged asphalt.Results showed that the addition of 2BPE and DBP reduced the difference in the solubility parameters between WVO and aged asphalt,thus improving the compatibility between WVO and aged asphalt.Additionally,using a combination of 2BPE and DBP in both aged asphalt and rejuvenator was found to be more effective than using either 2BPE or DBP alone.Finally,it was determined that evaluating the compatibility of WVO and aged asphalt using Van der Waals potential and non-bonding energy as evaluation indicators was more accurate than using electrostatic potential energy. 展开更多
关键词 road engineering aged asphalt compatibility molecular dynamics solubility parameter Flory-Huggins parameter
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Hypoglycemic Effect of Radix Et Rhizoma Salviae Miltiorrhizae,Guixi Green Tea and Their Compatibility on Mice
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作者 Chen YANG Zhaohui HUANG +6 位作者 Liqing TANG Wenjing HUANG Danyu CHEN Rujun SHI Suoyi HUANG Lixiang LU Shiyou ZHOU 《Medicinal Plant》 2024年第3期53-55,70,共4页
[Objectives]To explore the hypoglycemic effect of Radix Et Rhizoma Salviae Miltiorrhizae,Guixi green tea and their compatibility on mice,so as to provide more options for the adjuvant treatment of diabetes and improve... [Objectives]To explore the hypoglycemic effect of Radix Et Rhizoma Salviae Miltiorrhizae,Guixi green tea and their compatibility on mice,so as to provide more options for the adjuvant treatment of diabetes and improve the comprehensive utilization value of Guixi green tea.[Methods]After being fed adaptively for 7 d,60 SPF-grade male mice were intraperitoneally injected with alloxouracil(180 mg/kg)to induce hyperglycemia model,from which 35 mice with a successful model were selected.They were randomly divided into 5 groups(Danshen group,green tea group,compatible group,positive control group and blank control group),with 7 animals in each group.The mice in all groups were administered according to the dose of 200 mg/kg once a day for 15 d.After the last administration,their body weight was measured on the 15 th day after fasting for 12 h,and their fasting blood glucose was measured by tail clipping.[Results]After modeling,the mice in each group showed typical hyperglycemia symptoms,namely obvious polydipsia,polyphagia,polyuria and weight loss.Compared with the blank control group,Danshen group and green tea group had obvious hypoglycemic effect(P<0.05),and compatible group had significant hypoglycemic effect(P<0.01).Compared with the blank control group,the weight loss of diabetic mice could also be inhibited in green tea group and compatible group(P<0.05).[Conclusions]Danshen,Guixi green tea and their compatibility had the effect of lowering blood sugar,among which the compatible group had the most obvious effect. 展开更多
关键词 SALVIA miltiorrhiza Guixi green TEA compatibility BLOOD SUGAR
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Effects of Radix Puerariae, Radix Rehmanniae and Their Compatibility on Blood Glucose and Blood Lipids in Mice
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作者 Yumei ZHANG Yulin ZHAO +3 位作者 Yanmei QIN Jialing WEI Xiang QIN Suoyi HUANG 《Medicinal Plant》 2024年第1期45-47,共3页
[Objectives]To explore the effects of the compatibility of Radix Puerariae and Radix Rehmanniae on blood glucose and blood lipids in diabetic mouses.[Methods]Diabetic mouse model was established.The body weight and fa... [Objectives]To explore the effects of the compatibility of Radix Puerariae and Radix Rehmanniae on blood glucose and blood lipids in diabetic mouses.[Methods]Diabetic mouse model was established.The body weight and fasting blood glucose of mice were measured after 7 and 14 d of administration,and the biochemical indicators of blood lipids(TC,HDL-C,and LDL-C)were detected after 14 d of administration.[Results]Compared with the Radix Puerariae group and Radix Rehmanniae group,the compatibility group(1:2)had the best hypoglycemic effect(P<0.05),and TC and LDL-C in the compatibility group(2:1)significantly decreased(P<0.05),while HDL-C in the compatibility group(1:1)significantly increased(P<0.05).[Conclusions]Radix Puerariae,Radix Rehmanniae and their combination can reduce the blood glucose of diabetic mice.The compatibility group(1:2)had a significant hypoglycemic effect(P<0.05),and LDL-C in the compatibility group(2:1)significantly declined,while HDL-C in the compatibility group(1:1)rose significantly. 展开更多
关键词 Radix Puerariae Radix Rehmanniae compatibility Hypoglycemic effect Blood lipids
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Rapid evolution of T2/S-RNase genes in Fragaria linked to multiple transitions from self-incompatibility to self-compatibility 被引量:1
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作者 Wu Chen Hong Wan +4 位作者 Fang Liu Haiyuan Du Chengjun Zhang Weishu Fan Andan Zhu 《Plant Diversity》 SCIE CAS CSCD 2023年第2期219-228,共10页
The T2/RNase gene family is widespread in eukaryotes,and particular members of this family play critical roles in the gametophytic self-incompatibility(GSI) system in plants.Wild diploid strawberry(Fragaria)species ha... The T2/RNase gene family is widespread in eukaryotes,and particular members of this family play critical roles in the gametophytic self-incompatibility(GSI) system in plants.Wild diploid strawberry(Fragaria)species have diversified their sexual systems via self-incompatible and self-compatible traits,yet how these traits evolved in Fragaria remains elusive.By integrating the published and de novo assembled genomes and the newly generated RNA-seq data,members of the RNase T2 gene family were systematically identified in six Fragaria species,including three self-incompatible species(Fragaria nipponica,Fragaria nubicola,and Fragaria viridis) and three self-compatible species(Fragaria nilgerrensis,Fragaria vesca,and Fragaria iinumae).In total,115 RNase T2 genes were identified in the six Fragaria genomes and can be classified into three classes(Ⅰ-Ⅲ) according to phylogenetic analysis.The identified RNase T2 genes could be divided into 22 homologous gene sets according to amino acid sequence similarity and phylogenetic and syntenic relationships.We found that extensive gene loss and pseudogenization coupled with small-scale duplications mainly accounted for variations in the RNase T2 gene numbers in Fragaria.Multiple copies of homologous genes were mainly generated from tandem and segmental duplication events.Furthermore,we newly identified five S-RNase genes in three self-incompatible Fragaria genomes,including two in F.nipponica,two in F.viridis,and one in F.nubicola,which fit for typical features of a pistil determinant,including highly pistil-specific expression,highly polymorphic proteins and alkaline isoelectric point(pI),while no S-RNase genes were found in all three selfcompatible Fragaria species.Surprisingly,these T2/S-RNase genes contain at least one large intron(>10 kb).This study revealed that the rapid evolution of T2/S-RNase genes within the Fragaria genus could be associated with its sexual mode,and repeated evolution of the self-compatible traits in Fragaria was convergent via losses of S-RNase. 展开更多
关键词 FRAGARIA RNase T2 Self-(in)compatibility S-RNASE
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Epidemiological Investigation of Brucellosis Spondylitis and Optimal Selection of Clinical Drug Compatibility, Treatment Course and Treatment Plan
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作者 Xinming Yang Fei Liu Yanlin Yin 《Open Journal of Preventive Medicine》 CAS 2023年第5期129-138,共10页
Background: Brucellosis is a zoonotic endemic disease, the main source of infection is infected cattle, sheep, pigs and their products. In recent years, the global incidence of brucellosis spondylitis has increased ye... Background: Brucellosis is a zoonotic endemic disease, the main source of infection is infected cattle, sheep, pigs and their products. In recent years, the global incidence of brucellosis spondylitis has increased year by year, and it has spread from pastoral areas to semi-agricultural and semi-pastoral areas, agricultural areas and cities. It has changed from a mainly occupational disease to a mainly food-borne disease, and it is also a zoonotic specific spinal infectious disease that WHO and governments around the world pay great attention to. Due to the low cure rate and high recurrence rate of traditional drug therapy regimen. Therefore, to carry out epidemiological investigation and Related research on clinical drug therapy of brucellosis spondylitis has practical significance for improving diagnosis rate, cure rate and reducing recurrence rate. Objective: To analyze the epidemiological characteristics of Brucellosis spondylitis and explore the choice of drugs and the best drug treatment plan, so as to provide scientific basis for improving the prevention and control of the disease and treatment effect. Methods: Clinical epidemiodogical materials were collected from 113 patients with brucellar spondylitis. All these patients were divided into 5 different groups according to 5 kinds of drugs adopted respectively, and then the patients were given different course of treatment. Results: In the 113 patients, brucellar spondylitis morbility of female patients were higher than that of male ones, and the morbility of Bashang were higher than that of Baxia. These patients were infected mainly through browsing and breeding beasts. Lumbars were the major focus of infection. It was very comnlon that two adjacent lumbars were involved in concurrently. L4 was the most common infection location and its demolishment was most serious. The curative effect of group treated with doxycycline was better than that of group treated without doxycycline. If the course of treatment Was increased, the curative effect Was not increased obviously. Conclusions: There are characteristic features in clinical epidemiology of brucell spondylitis. Doxycycline + Rifampicin + Sulfamethoxazole was used as the preferred antibiotic. Using antibiotics adequately and jointly by two courses of treatment for a long time is the most reasonable way to treat the disease and prevent the disease from recurrence. 展开更多
关键词 BRUCELLOSIS SPONDYLITIS EPIDEMIOLOGY Drug compatibility Treatment Course PHARMACOTHERAPY Optimize Treatment
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Enhancing the compatibility of the amyloid-dye hybrid nanostructure for improved photo-biocatalysis
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作者 Zhen Dong Yanying Wang +2 位作者 Qin Yang Dan Li Peng Wu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2023年第3期430-437,I0012,共9页
Artificial photosynthesis is significant for renewable energy generation,sustainable development,and environmental protection.Dye-protein hybrids are promising for developing photosynthesis mimics(e.g.,photo-biocataly... Artificial photosynthesis is significant for renewable energy generation,sustainable development,and environmental protection.Dye-protein hybrids are promising for developing photosynthesis mimics(e.g.,photo-biocatalysis),but their performances are far lower than the plant photosystems,partially because of the incompatibility between dye and the protein matrix that limits excited state electron transfer of the included dyes.Here,using ThT-insulin amyloid assembly as a model system,we proposed that increasing the dye-protein compatibility could lead to the improved photo-biocatalytic performance.A ThT derivative,ThTPD,was designed with the same electron acceptor but extended π-conjugated donor structure.When integrated into the insulin amyloid,the extended π-conjugated donor structure allowed increased binding affinity and energy with the amyloid matrix,thus better electron transport to the mediator to drive the photocatalytic reaction.Meanwhile,compared with ThT, ThTPD exhibited improved light absorption and longer excited state lifetime.The photo-biocatalytic performance of ThTPD-insulin amyloid was greatly improved as compared with that of ThT in reduced nicotinamide adenine dinucleotide(NADH) regeneration.When integrating with NADH-dependent L-glutamate reductase,the efficiency of the ThTPD-insulin amyloid hybrid was 2.8-fold higher than that of ThT in glutamate generation,showing promising feature in biocatalytic solar-to-chemical conversion. 展开更多
关键词 Photo-biocatalysis Dye-protein assembly Insulin amyloid THT compatibility
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Exploring the compatibility theory of traditional Chinese medicine formulae:the disassembled prescriptions study
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作者 Xue Yang Xin-Yuan Luan 《Traditional Medicine Research》 2023年第5期38-43,共6页
Traditional Chinese medicine(TCM)has become very popular in the treatment of complex diseases worldwide in recent decades.Despite the promising performance of TCM,how herbs work synergistically in a formula and their ... Traditional Chinese medicine(TCM)has become very popular in the treatment of complex diseases worldwide in recent decades.Despite the promising performance of TCM,how herbs work synergistically in a formula and their therapeutic targets remain ambiguous.This largely limits the correct use and modernization of TCM formulas clinically.The study of disassembled prescriptions is important for investigating the compatibility theory of Chinese medicines.By dissecting the mechanisms of TCM formulae,the compatibility principles of some well-known formulae,such as Realgar-Indigo naturalis,have been elucidated to a certain extent.In this review,several common methods of disassembled prescription studies are summarized,including those of single herb or mineral,sub-prescription,active ingredients or effective parts,large formulae,and systems pharmacology studies,as well as the methods of grouping based on the properties or efficacy of Chinese medicines,in order to provide evidence for formulae study.Moreover,some challenges to be addressed in disassembled prescriptions studies have been identified in this review. 展开更多
关键词 compatibility theory of formulae traditional Chinese medicine disassembled prescriptions study systems pharmacology
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Compatibility Rules of Prescriptions of Tibetan Medicine Polygonatum cirrhifolium Based on Data Mining
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作者 Nianggecairang Zhuomacuomao +2 位作者 Gelacuo Gongbajia Cairangnanjia 《Medicinal Plant》 CAS 2023年第3期9-14,共6页
[Objectives]To study the prescription compatibility rules of the Tibetan medicine Polygonatum cirrhifolium(Polygonati Rhizoma,Huangjing)based on data mining,so as to provide data support for clinical application and n... [Objectives]To study the prescription compatibility rules of the Tibetan medicine Polygonatum cirrhifolium(Polygonati Rhizoma,Huangjing)based on data mining,so as to provide data support for clinical application and new drug development.[Methods]Prescriptions containing Tibetan medicine Huangjing were collected from Tibetan Medicine Prescriptions Encyclopedia and Tibetan Medicine Classic Literature Collection.The Traditional Chinese Medicine Inheritance Computing System(TCMICS 3.0)and R version 4.1.3 were used to mine and analyze the compatibility rules of prescriptions containing Tibetan medicinal material Huangjing,the rules of medication for high-frequency diseases,and the association rules of various medicinal materials.[Results]A total of 124 prescriptions were collected from the classic literature of Tibetan medicine,and the frequency statistical analysis showed that drugs compatible with Huangjing(≥15)included Tianmendong(Root of Cochinchinese Asparagus)(80),Mirabilis himalaica(Edgew.)Heimerl(Himalayan purple jasmine)(72),Jili(Tribuli Fructus)(70),Tibetan Aoruqin(Vicatia coniifolia)(58),Baidoukou(Round Cardamom Fruit)(47),Hezi(Chebulae Fructus)(45),Shouzhangshen(Rhizome of Conic Gymnadenia)(28),Yuganzi(Phyllanthi Fructus)(26),Pomegranate(25),Maohezi(Terminaliae Belliricae Fructus)(24),Zicaorong(Lacca)(23),Rougui(Cinnamomi Cortex)(15).The main diseases were yellow water disease(20),gynecological diseases(19),kidney cold disease(17),and other Tibetan medicine diseases.Association rule analysis showed that the drug combinations with the highest frequency were Huangjing—Tianmendong,Huangjing—Himalayan purple jasmine,and Huangjing—Jili.[Conclusions]The frequency of combined use of Tibetan medicine Huangjing with dry yellow water,tonifying kidney and diuresis,nourishing health,and treating gynecological diseases is relatively high. 展开更多
关键词 Tibetan medicinal material Polygonatum cirrhifolium(Polygonati Rhizoma Huangjing) PRESCRIPTIONS compatibility Rules
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Compatibility Rules of Prescriptions of Tibetan Medicinal Material Mirabilis himalaica(Edgew.)Heimerl Based on Data Mining
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作者 Zhuomacuomao Duojierenqing Cairangnanjia 《Medicinal Plant》 CAS 2023年第1期5-11,共7页
[Objectives]To study the prescription compatibility rules of the Tibetan medicinal material Mirabilis himalaica(Edgew.)Heimerl(Himalayan purple jasmine)based on data mining,and to provide reference for clinical applic... [Objectives]To study the prescription compatibility rules of the Tibetan medicinal material Mirabilis himalaica(Edgew.)Heimerl(Himalayan purple jasmine)based on data mining,and to provide reference for clinical application and new drug development.[Methods]The literature data were collected and the prescriptions containing Himalayan purple jasmine were sorted and classified by Microsoft Excel 2019 software.The Traditional Chinese Medicine Inheritance Computing System(TCMICS 3.0)was used to statistically analyze the high-frequency drugs and core drug combinations,the frequency of disease treatment,and the rules of"tastes transforming flavors"of drugs.The FP-tree algorithm was used to analyze the association rules among various Tibetan medicinal materials in the prescriptions,and different supports were set to analyze the compatibility rules of the prescriptions.[Results]There were a total of 129 prescriptions containing Himalayan purple jasmine,297 medicinal materials used in combination with it,and 34 Tibetan medicinal materials with a frequency of≥15.The medicinal flavors were mostly sweet,bitter,and pungent.Among the three flavors,bitterness and sweetness were the majority.At the same time,the medicinal properties were blunt,soft,cool,and warm.A total of 130 kinds of diseases were involved,among which 8 kinds of diseases such as gynecology,kidney cold and yellow water disease had a high frequency.Through association rule analysis,33 commonly used core drug combinations were obtained.The support,confidence,and frequency of the five drug combinations[Jili(Tribuli Fructus),Huangjing(Polygonati Rhizoma),Tianmendong(Root of Cochinchinese Asparagus),and Tibetan Aoruqin(Vicatia coniifolia)]→Himalayan purple jasmine were the basic prescription of Tibetan medicine Wudagen Powder.The drug combinations with higher confidence included Bibo(Piperis Longi Fructus)→Himalayan purple jasmine,Pomegranate(Punica granatum→Himalayan purple jasmine,Baidoukou(Round Cardamom Fruit)→Himalayan purple jasmine,Hezi(Chebulae Fructus)→Himalayan purple jasmine.Jili(Tribuli Fructus)→Himalayan purple jasmine,Huangjing(Polygonati Rhizoma)→Himalayan purple jasmine and Tianmendong(Root of Cochinchinese Asparagus)→Himalayan purple jasmine had highest frequency.[Conclusions]Through the TCMICS,this paper analyzed the compatibility rules of commonly used drugs containing Himalayan purple jasmine and the characteristics of the main diseases.It can be seen that Himalayan purple jasmine is sweet in taste and warm in nature.It assists sovereign drugs in the form of ministerial drugs,which enhances the effect of regulating"long"and nourishing,and plays the role of regulating"long",dispelling cold,and reconciling various drugs,which embodies the compatibility rules of sovereign and ministerial drugs of Tibetan medicines.The main diseases of Himalayan purple jasmine are related to"long"regulation,and it is mostly used in the treatment of gynecological diseases after being combined with other drugs to form a prescription.Most drugs in the prescriptions are sweet,which is the therapeutic principle of regulating"long"and nourishing,and verifies the scientific and rational principle of clinical use of Tibetan medicine.In the prescription,the medicinal properties include both warm and cool,and the medicinal taste is sweet and bitter,which is in line with the compatibility theory of"tastes transforming flavors"in traditional Tibetan medicine prescriptions. 展开更多
关键词 Tibetan medicine Mirabilis himalaica(Edgew.)Heimerl(Himalayan purple jasmine) compatibility RULES Prescription
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Compatibility mechanism of Chinese medicine formula:state of the art and perspectives
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作者 Yi-Xuan Wang Yu-Xi Huang +3 位作者 Xu-Hui Wang Feng Xie Xiang-Long Duan Cui-Juan Li 《Drug Combination Therapy》 2023年第2期1-6,共6页
Traditional Chinese medicine(TCM)has been practiced in China and surrounding countries for thousands of years and has gradually attracted the attention of Western countries.After reasonable compatibility,TCMs could pl... Traditional Chinese medicine(TCM)has been practiced in China and surrounding countries for thousands of years and has gradually attracted the attention of Western countries.After reasonable compatibility,TCMs could play the key role of enhancing efficacy and reducing toxicity,which has significant therapeutic advantages in the treatment of complex diseases in clinical practice.While the TCM compatibility is not the simple addition of drugs.Under the appropriate dosage ratio,multiple TCMs can play a synergistic role to realize the overall regulation of TCM treatment.Therefore,it is of critical essential to study the compatibility of TCM formula to promote TCM modernization,new drug development and clinical application.Recently,under the guidance of TCM theory,many researches on the composition,pharmacodynamic activity and pharmacokinetic properties of TCM formula have emerged by integrating new technologies and new methods,revealing the scientific connotation of the compatibility of TCM formula from different perspectives and levels.This paper introduces the research progress of compatibility rules from different levels of compatibility,compatibility for synergistic enhancement and detoxification,and application of cutting-edge technology,with representative cases,in order to provide ideas and references for further study on TCM compatibility. 展开更多
关键词 traditional Chinese medicine compatibility rules FORMULA synergism DETOXIFICATION
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蒲公英、忍冬藤抗菌活性组分及配伍研究 被引量:2
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作者 马艳妮 李智宁 +5 位作者 张丽先 李飞飞 魏悦 于立芹 任峰 朱政 《饲料工业》 CAS 北大核心 2024年第2期102-109,共8页
为了探寻蒲公英和忍冬藤高效抗菌活性组分及其配伍活性,试验以蒲公英和忍冬藤为研究对象,通过70%乙醇提取、大孔树脂D101柱层析和抗菌活性跟踪相结合的方式优选各自的高效抗菌活性组分,并对这些组分进行总黄酮、有机酸和多酚含量分析和... 为了探寻蒲公英和忍冬藤高效抗菌活性组分及其配伍活性,试验以蒲公英和忍冬藤为研究对象,通过70%乙醇提取、大孔树脂D101柱层析和抗菌活性跟踪相结合的方式优选各自的高效抗菌活性组分,并对这些组分进行总黄酮、有机酸和多酚含量分析和活性配伍研究。结果表明蒲公英和忍冬藤的高效抗菌活性组分分离工艺为:先用70%乙醇回流提取,浓缩后用大孔树脂D101柱层析,70%或50%乙醇洗脱部位即为它们的高效抗菌活性组分。这些组分对9种供试病原菌都具有较强的广谱抗菌性,蒲公英的最小抑菌浓度(MIC)和最小杀菌浓度(MBC)分别约为1.95 mg/mL和15.63 mg/mL,忍冬藤的MIC和MBC分别约为1.95 mg/mL和31.25 mg/mL。且含量分析显示,蒲公英高效抗菌活性组分黄酮和多酚含量相对较高,忍冬藤高效抗菌活性组分多酚含量相对较高。配伍研究发现,当蒲公英高效抗菌活性部位与少量忍冬藤水洗脱部位(16∶1~4∶1)或其高效抗菌部位(16∶1~1∶1)配伍使用时,对部分供试菌的抗菌活性存在一定的相加作用。说明所得的蒲公英和忍冬藤高效抗菌活性组分提取分离工艺简单、易得,广谱抗菌作用强,合适的配伍使用可以实现更好的抗菌作用。 展开更多
关键词 蒲公英 忍冬藤 抗菌活性 活性组分 配伍
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基于Comsol软件的电磁兼容课程案例式教学设计 被引量:2
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作者 白洁 陈玉 孔忻 《高教学刊》 2024年第S02期111-115,共5页
该文介绍基于Comsol软件的电磁兼容课程案例式教学方法。通过案例教学和仿真,学生将理论知识应用于实际问题,深入理解电磁兼容的概念和原理。通过仿真案例的可视化结果,学生直观地理解电磁辐射和传导,观察不同参数对电磁兼容性的影响。... 该文介绍基于Comsol软件的电磁兼容课程案例式教学方法。通过案例教学和仿真,学生将理论知识应用于实际问题,深入理解电磁兼容的概念和原理。通过仿真案例的可视化结果,学生直观地理解电磁辐射和传导,观察不同参数对电磁兼容性的影响。结果表明,仿真案例具有直观性和可视化等优势,同时又有简化模型、缺乏实际操作经验和对计算机的依赖等局限性。在设计仿真案例时,要充分发挥其优势,规避不足,为学生的学习提供实践性、直观性和灵活性,培养学生的工程设计与研发能力。 展开更多
关键词 Comsol软件 电磁兼容 案例式教学 教学设计 仿真案例
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电针“天枢”与“天枢”配伍“上巨虚”对肠易激综合征大鼠行为学和结肠功能的影响 被引量:1
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作者 刘婷婷 张擎宇 +5 位作者 赵香顺 石运来 于燕南 王正文 陈少宗 杨添淞 《中国中医基础医学杂志》 CAS CSCD 2024年第2期245-250,共6页
目的观察并比较电针“天枢”与“天枢”配伍“上巨虚”对肠易激综合征(irritable bowel syndrome,IBS)模型大鼠情绪和结肠功能影响,初步探讨天枢配伍上巨虚是否存在协同或叠加效应。方法雄性Wistar大鼠分为空白组(10只)和造模组(45只),... 目的观察并比较电针“天枢”与“天枢”配伍“上巨虚”对肠易激综合征(irritable bowel syndrome,IBS)模型大鼠情绪和结肠功能影响,初步探讨天枢配伍上巨虚是否存在协同或叠加效应。方法雄性Wistar大鼠分为空白组(10只)和造模组(45只),采用慢性和急性应激相结合方法连续干预10 d制备模型,将制备成功IBS模型大鼠随机分为模型组(8只)、天枢组(8只)、天枢配伍上巨虚组(8只);天枢组、天枢配伍上巨虚组连续电针干预治疗14 d;干预结束后,分别对各组大鼠进行高架十字迷宫实验、结肠痛敏阈值测定,检测血清5-羟色胺(5-hydroxytryptamine,5-HT)含量以及结肠5-羟色胺4受体(5-hydroxytryptamine 4 receptor,5-HT 4 R)蛋白表达。结果与模型组比较,电针天枢组、电针天枢配伍上巨虚组进入开放臂(open arm entry,OE)次数百分比和开臂停留时间(open arm time,OT)百分比增加(P<0.01);结肠痛敏阈值显著升高(P<0.01);血清5-HT含量减少(P<0.05);结肠5-HT 4 R蛋白相对表达量增加(P<0.05)。两电针组之间比较,OE%、OT%、结肠痛敏阈值、血清5-HT含量以及结肠5-HT 4 R蛋白相对表达量的差异无统计学意义。结论电针“天枢”与“天枢”配伍“上巨虚”均能调节大鼠情绪心理行为的异常和改善结肠功能紊乱症状,但电针“天枢”配伍“上巨虚”相较于电针“天枢”未表现明显的穴位协同或叠加效应。 展开更多
关键词 肠易激综合征 天枢配伍上巨虚 高架十字迷宫 结肠功能
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苜蓿混播方式及比例对混播草地生产力和稳定性的影响 被引量:1
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作者 张永亮 滕泽 +2 位作者 郝凤 于铁峰 张玉霞 《草业学报》 CSCD 北大核心 2024年第2期185-197,共13页
为了探究适合科尔沁沙地的禾豆混播模式,将紫花苜蓿按8个水平(占单播量的5%,10%,15%,20%,25%,30%,35%,40%,B_(1)~B_(8))和2种方式(间行A_(1)和交叉A_(2))混播到2月龄的无芒雀麦草地,分析混播方式与混播比例对禾豆混播草地生产力和群落... 为了探究适合科尔沁沙地的禾豆混播模式,将紫花苜蓿按8个水平(占单播量的5%,10%,15%,20%,25%,30%,35%,40%,B_(1)~B_(8))和2种方式(间行A_(1)和交叉A_(2))混播到2月龄的无芒雀麦草地,分析混播方式与混播比例对禾豆混播草地生产力和群落稳定性的影响。结果表明:混播方式对第3茬无芒雀麦产量影响显著,A_(2)处理显著高于A_(1)(P<0.05)。A_(1)处理1~3茬及全年苜蓿产量均高于A_(2),其中第3茬及全年苜蓿产量差异显著(P<0.05)。禾豆总产量除2茬A_(1)显著高于A_(2)(P<0.05)外,其余无显著差异。A_(2)处理2、3茬无芒雀麦相对密度(RD)和3茬相对产量(RY)显著高于A_(1)。苜蓿混播方式对各茬苜蓿RD和RY没有显著影响,而对全年苜蓿RY影响显著,A_(1)显著高于A_(2)(P<0.05)。A_(1)处理2茬及全年相对产量总和(RYT)显著大于A_(2)(P<0.05)。随着苜蓿混播比例增加,全年苜蓿产量、禾豆产量和RYT呈增长趋势,而无芒雀麦产量、无芒雀麦和苜蓿RD、RY均呈下降趋势。不同苜蓿混播比例下各茬无芒雀麦RY均小于1,而苜蓿RY均大于1。混播处理全年RYT均大于1,混播20%~40%苜蓿第3茬RYT>1。模糊综合评价结果表明A_(2)B_4组合最优,其次是A_(2)B_(3)组合。综合考虑牧草产量和群落稳定性,在固定播量的2月龄无芒雀麦草地上交叉混播15%~20%苜蓿较适宜。 展开更多
关键词 禾豆混播 牧草产量 种间相容性 群落稳定性 模糊综合评价
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绿色金融支持和美乡村建设的机制与路径研究 被引量:2
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作者 李明贤 徐豫湘 《世界农业》 CSSCI 2024年第4期72-82,共11页
新时代新征程,建设宜居宜业和美乡村,对于满足国民对美好生活的新需求、提高乡村社会文明程度、推进农业农村现代化,进而全面建成社会主义现代化强国具有重要意义。这一目标的实现需要打造生态优质的“宜居”乡村、生产兴旺的“宜业”... 新时代新征程,建设宜居宜业和美乡村,对于满足国民对美好生活的新需求、提高乡村社会文明程度、推进农业农村现代化,进而全面建成社会主义现代化强国具有重要意义。这一目标的实现需要打造生态优质的“宜居”乡村、生产兴旺的“宜业”乡村、生活幸福的“和美”乡村。然而目前和美乡村建设面临着生态环境与经济发展相冲突及乡村建设资金短板尚未解决的现实挑战,为此本文提出要借助绿色金融之手来解决这些问题。绿色金融可以通过政府引导的积累机制与市场参与的投资机制,促进产业生态化与生态产业化实现生态补偿和修复及经营和权属交易。此外,借助绿色金融工具可以降低交易成本,从而实现乡村治理的激励相容,最终达成宜居宜业和美乡村建设的目标。 展开更多
关键词 宜居宜业 外部效应 激励相容 产业生态化 生态产业化
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危险废物渗滤液阳离子和应力作用下膨润土化学相容性研究
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作者 杨延梅 梁柱 +4 位作者 姚光远 刘玉强 徐亚 刘景财 钱璨 《环境工程技术学报》 CAS CSCD 北大核心 2024年第4期1337-1345,共9页
膨润土因其优异的防渗性能被用于危险废物填埋场防渗屏障的构筑,但其防渗性能通常会受到渗滤液和应力的影响。通过渗滤液采样分析设置不同浓度阳离子溶液,系统探究实际渗滤液组分对膨润土防渗性能的影响规律;选用Ca^(2+)作为特征阳离子... 膨润土因其优异的防渗性能被用于危险废物填埋场防渗屏障的构筑,但其防渗性能通常会受到渗滤液和应力的影响。通过渗滤液采样分析设置不同浓度阳离子溶液,系统探究实际渗滤液组分对膨润土防渗性能的影响规律;选用Ca^(2+)作为特征阳离子研究不同应力条件下膨润土渗透系数变化规律;同时结合Zeta电位和DLVO理论计算,阐明渗滤液组分和应力作用对膨润土化学相容性影响规律。结果表明,渗滤液中Al^(3+)、Fe^(3+)、Zn^(2+)、Ni^(2+)、Cu^(2+)、Fe^(2+)、Mn^(2+)浓度为0~0.20 mmol/L时,对膨润土膨胀特性和渗透特性影响较小。Mg^(2+)、Ca^(2+)、K^(+)、Na^(+)浓度为0.20~50 mmol/L时,Ca^(2+)对膨润土膨胀特性和渗透特性影响较大,Ca^(2+)浓度由1 mmol/L上升到50 mmol/L时,渗透系数由1.15×10^(−7)cm/s急速上升到6.34×10^(−6)cm/s。Ca^(2+)浓度和应力通常通过影响水化后膨润土孔隙比进而影响其渗透特性,相同Ca^(2+)浓度条件下,渗透系数随应力增加而逐渐降低。Zeta电位和DLVO理论分析表明,Ca^(2+)浓度增大会导致膨润土表面负电势减弱,引起膨润土双电层厚度减小,使膨润土中蒙脱石的层间距变小,导致膨润土膨胀特性和渗透特性降低。因此,填埋过程中应优化危险废物固化稳定化工艺,从源头减少渗滤液中Ca^(2+)浓度;同时还应研发新型膨润土复合材料,提高膨润土在Ca^(2+)等高浓度盐溶液中的防渗性能,防控危险废物填埋场渗漏风险。 展开更多
关键词 膨润土 危险废物渗滤液 化学相容性 渗透特性 应力
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罪刑相适应是刑法分则解释的铁则 被引量:1
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作者 陈洪兵 《政法论丛》 CSSCI 北大核心 2024年第3期127-138,共12页
“以刑制罪”论者主张为了所谓量刑公正而可以任意变换罪名,无视犯罪构成原理和罪刑法定原则,因而不可取。罪刑相适应作为刑法分则解释的铁则,应贯彻到刑法分则解释适用的每一个具体解释结论和处理结果当中。为实现罪刑相适应,根本无需... “以刑制罪”论者主张为了所谓量刑公正而可以任意变换罪名,无视犯罪构成原理和罪刑法定原则,因而不可取。罪刑相适应作为刑法分则解释的铁则,应贯彻到刑法分则解释适用的每一个具体解释结论和处理结果当中。为实现罪刑相适应,根本无需严格区分法条竞合和想象竞合。选择罪名和概括罪名也能并罚。为开山采石以确保安全的方式运输、储存爆炸物的,不应作为犯罪处理。危险驾驶、妨害安全驾驶、危险作业造成伤亡结果的,只能成立交通肇事罪、危险物品肇事罪、责任事故犯罪,而不能成立以危险方法危害公共安全罪。我国刑法分则规定的行为并不都是实行行为,应准确区分预备行为与实行行为。 展开更多
关键词 罪刑相适应 以刑制罪 竞合 加重犯 实行行为
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面向多目标优化主动运维的电能表远程在线评价系统设计 被引量:1
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作者 张福州 刘栋果 +2 位作者 张嘉岷 陈文 李显忠 《微型电脑应用》 2024年第3期76-79,共4页
针对传统电能表远程在线评价系统中存在的系统建造成本耗费较大、评价结构过于繁琐等问题,从评价系统的构建和评价算法两方面开展研究。在评价系统的设计方面,加入反馈,使得该评价系统不仅可以整合各项评价指标进行规律化的采集,还可以... 针对传统电能表远程在线评价系统中存在的系统建造成本耗费较大、评价结构过于繁琐等问题,从评价系统的构建和评价算法两方面开展研究。在评价系统的设计方面,加入反馈,使得该评价系统不仅可以整合各项评价指标进行规律化的采集,还可以对评价指标进行实时反馈,提高了评价的效率和评价信息传输的效率。在评价算法方面,基于解耦评价算法对电能表的运行状态和采集数据进行评价,对数据信息进行归纳处理,并根据大量的数据样本进行条理化分析评价。通过仿真实验可知,硬件反馈线路的数据传输效率高达98.6%,具有很好的传输能力。 展开更多
关键词 核心兼容结构 解耦评价算法 电能表 在线评价系统 反馈线路
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基于关系图的Linux内核兼容性量化分析研究
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作者 秦莹 阳娅婧 +1 位作者 马俊 万家齐 《计算机工程与科学》 CSCD 北大核心 2024年第10期1720-1734,共15页
内核升级导致设备驱动模块、应用系统库的移植工作缺少有效的理论指导,给操作系统开发和部署带来诸多不便。针对上述情况,提出基于内核模块差异性检测和依赖关系分析的内核兼容性量化分析方法,结合开源Linux内核,构造内核模块依赖关系图... 内核升级导致设备驱动模块、应用系统库的移植工作缺少有效的理论指导,给操作系统开发和部署带来诸多不便。针对上述情况,提出基于内核模块差异性检测和依赖关系分析的内核兼容性量化分析方法,结合开源Linux内核,构造内核模块依赖关系图,统计内核模块出入度、依赖深度、中心性等影响内核兼容性的图特征,分析系统调用和导出函数2类兼容性强相关函数的变化情况及其对内核兼容性的影响,给出测算内核模块兼容率和影响域的基本方法,并在Linux内核5.x系列版本和麒麟典型版本中进行实验验证。 展开更多
关键词 内核 兼容性量化 影响域
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聚丙烯/木粉复合材料的制备及性能
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作者 洪浩群 刘凯丽 +3 位作者 于日志 李雪松 岑兰 张海燕 《合成树脂及塑料》 CAS 北大核心 2024年第5期11-16,共6页
分别采用聚丙烯的固相接枝共聚物和熔融接枝共聚物作为聚丙烯/木粉复合材料的界面改性剂,研究两种多单体接枝共聚物用量对复合材料界面结构、拉伸性能、弯曲性能、抗冲击性能等的影响,并根据拉伸性能数据计算复合材料的界面黏结强度。... 分别采用聚丙烯的固相接枝共聚物和熔融接枝共聚物作为聚丙烯/木粉复合材料的界面改性剂,研究两种多单体接枝共聚物用量对复合材料界面结构、拉伸性能、弯曲性能、抗冲击性能等的影响,并根据拉伸性能数据计算复合材料的界面黏结强度。结果表明:两种多单体接枝共聚物均能有效地提高复合材料的力学性能,并维持良好的热稳定性;随多单体接枝共聚物用量的增加,复合材料的力学性能提高,当多单体接枝共聚物用量为5 phr时,复合材料的界面相容性较稳定,力学性能最佳,界面黏结强度参数从2.56升至3.50以上,表明复合材料具有较强的界面黏结强度。 展开更多
关键词 聚丙烯 木粉 力学性能 界面相容性 接枝共聚物
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