Steady growth of forex reserves makes it possible for China to bring currency-related risks under control more easily A ccording to the State Administration of Foreign Exchange,by the end of January,China’s foreign e...Steady growth of forex reserves makes it possible for China to bring currency-related risks under control more easily A ccording to the State Administration of Foreign Exchange,by the end of January,China’s foreign exchange(forex)reserves had hit US$3.18 trillion,up by US$56.8 billion,or 1.82 percent,over the end of 2022,the fourth monthly hike in a row.展开更多
As the world's largest bartending competition,Diageo Reserve World Class allows mix masters to show off their skills and garner recognition.This year,more than 200 brilliant booze stars from 120 bars around the co...As the world's largest bartending competition,Diageo Reserve World Class allows mix masters to show off their skills and garner recognition.This year,more than 200 brilliant booze stars from 120 bars around the country have been invited to the fifth annual World Class competition for the China region-to be held May 13 in Shanghai(location TBA).展开更多
Hair cell regeneration is the fundamental method of correcting hearing loss and balance disorders caused by hair cell damage or loss. How to promote hair cell regeneration is a hot focus in current research. In mammal...Hair cell regeneration is the fundamental method of correcting hearing loss and balance disorders caused by hair cell damage or loss. How to promote hair cell regeneration is a hot focus in current research. In mammals, cochlear hair cells cannot be regenerated and few vestibular hair cells can be renewed through spontaneous regeneration. However, Math1 gene transfer allows a few inner ear cells to be transformed into hair cells in vitro or in vivo. Hair cells can be renewed through two possible means in birds： supporting cell differentiation and transdifferentiation with or without cell division. Hair cell regeneration is strongly associated with cell proliferation. Therefore, this study explored the relationship between Math1-induced vestibular hair cell regeneration and cell division in mammals. The mouse vestibule was isolated to harvest vestibular epithelial cells. Ad-Math1-enhanced green fluorescent protein （EGFP） was used to track cell division during hair cell transformation.5-Bromo-2′-deoxyuridine （BrdU） was added to track cell proliferation at various time points. Immunocytochemistry was utilized to determine cell differentiation and proliferation. Results demonstrated that when epithelial cells were in a higher proliferative stage, more of these cells differentiated into hair cells by Math1 gene transfer. However, in the low proliferation stage, no BrdU-positive cells were seen after Math1 gene transfer. Cell division always occurred before Math1 transfection but not during or after Math1 transfection, when cells were labeled with BrdU before and after Ad-Math1-EGFP transfection. These results confirm that vestibular epithelial cells with high proliferative potential can differentiate into new hair cells by Math1 gene transfer, but this process is independent of cell proliferation.展开更多
花粉产量是定量重建古植被、古气候的必要条件,目前花粉产量包括相对花粉产量和绝对花粉产量。由于较难获得多年连续的花粉沉积数据,学者多倾向于使用相对花粉产量进行古植被定量重建。相对花粉产量是某一花粉类型相对于同一参考种的花...花粉产量是定量重建古植被、古气候的必要条件,目前花粉产量包括相对花粉产量和绝对花粉产量。由于较难获得多年连续的花粉沉积数据,学者多倾向于使用相对花粉产量进行古植被定量重建。相对花粉产量是某一花粉类型相对于同一参考种的花粉产量的比值(参考种通常选取植物群落和花粉组合中出现频率较高的同一花粉类型),可通过ERV(Extended R-value)模型进行估算,但其准确性受植被调查方法和模型假设条件影响较大。本文介绍了估算相对花粉产量所需的植被调查方法和利用花粉产量定量重建植被景观的模型。目前较成熟的模型为景观重建模型(Landscape Reconstruction Algorithm),包括REVEALS模型(Regional Estimates of Vegetation Abundance from Large Sites,适用于面积≥1~5km^2的沉积盆地植被重建)和LOVE模型(Local Vegetation Estimates,适用于面积为0.1~1.0km^2的沉积盆地植被重建)。欧洲及我国不同区域相对花粉产量和REVEALS模型定量重建研究结果均表明,重建后的古植被景观能较好反映当地的古植被组成。展开更多
文摘Steady growth of forex reserves makes it possible for China to bring currency-related risks under control more easily A ccording to the State Administration of Foreign Exchange,by the end of January,China’s foreign exchange(forex)reserves had hit US$3.18 trillion,up by US$56.8 billion,or 1.82 percent,over the end of 2022,the fourth monthly hike in a row.
文摘As the world's largest bartending competition,Diageo Reserve World Class allows mix masters to show off their skills and garner recognition.This year,more than 200 brilliant booze stars from 120 bars around the country have been invited to the fifth annual World Class competition for the China region-to be held May 13 in Shanghai(location TBA).
基金supported by the National Natural Science Foundation of China(NSFC)grant No.81420108010,81271084 to FLC,81370022,81570920,81000413 to DR,81200740 to JMY,81200738 to NC,81371093 to ZH,81400460 to ZG,81200739 to JW+2 种基金973 Program,grant No.2011CB504500 and 2011CB504506The Innovation Project of Shanghai Municipal Science and Technology Commission,grant No.11411952300 to FLCthe Training Program of the Excellent Young Talents of the Shanghai Municipal Health System,grant No.XYQ2013084 to DR
文摘Hair cell regeneration is the fundamental method of correcting hearing loss and balance disorders caused by hair cell damage or loss. How to promote hair cell regeneration is a hot focus in current research. In mammals, cochlear hair cells cannot be regenerated and few vestibular hair cells can be renewed through spontaneous regeneration. However, Math1 gene transfer allows a few inner ear cells to be transformed into hair cells in vitro or in vivo. Hair cells can be renewed through two possible means in birds： supporting cell differentiation and transdifferentiation with or without cell division. Hair cell regeneration is strongly associated with cell proliferation. Therefore, this study explored the relationship between Math1-induced vestibular hair cell regeneration and cell division in mammals. The mouse vestibule was isolated to harvest vestibular epithelial cells. Ad-Math1-enhanced green fluorescent protein （EGFP） was used to track cell division during hair cell transformation.5-Bromo-2′-deoxyuridine （BrdU） was added to track cell proliferation at various time points. Immunocytochemistry was utilized to determine cell differentiation and proliferation. Results demonstrated that when epithelial cells were in a higher proliferative stage, more of these cells differentiated into hair cells by Math1 gene transfer. However, in the low proliferation stage, no BrdU-positive cells were seen after Math1 gene transfer. Cell division always occurred before Math1 transfection but not during or after Math1 transfection, when cells were labeled with BrdU before and after Ad-Math1-EGFP transfection. These results confirm that vestibular epithelial cells with high proliferative potential can differentiate into new hair cells by Math1 gene transfer, but this process is independent of cell proliferation.
文摘花粉产量是定量重建古植被、古气候的必要条件,目前花粉产量包括相对花粉产量和绝对花粉产量。由于较难获得多年连续的花粉沉积数据,学者多倾向于使用相对花粉产量进行古植被定量重建。相对花粉产量是某一花粉类型相对于同一参考种的花粉产量的比值(参考种通常选取植物群落和花粉组合中出现频率较高的同一花粉类型),可通过ERV(Extended R-value)模型进行估算,但其准确性受植被调查方法和模型假设条件影响较大。本文介绍了估算相对花粉产量所需的植被调查方法和利用花粉产量定量重建植被景观的模型。目前较成熟的模型为景观重建模型(Landscape Reconstruction Algorithm),包括REVEALS模型(Regional Estimates of Vegetation Abundance from Large Sites,适用于面积≥1~5km^2的沉积盆地植被重建)和LOVE模型(Local Vegetation Estimates,适用于面积为0.1~1.0km^2的沉积盆地植被重建)。欧洲及我国不同区域相对花粉产量和REVEALS模型定量重建研究结果均表明,重建后的古植被景观能较好反映当地的古植被组成。
