Aromatherapy in traditional Chinese medicine integrates the principles of traditional Chinese medicine and Western essential oil therapy,utilizing plant essential oils to regulate qi and blood,unblock meridians,and ha...Aromatherapy in traditional Chinese medicine integrates the principles of traditional Chinese medicine and Western essential oil therapy,utilizing plant essential oils to regulate qi and blood,unblock meridians,and harmonize emotions.Rosemary essential oil,a commonly used substance,exhibits anti-inflammatory,analgesic,and mood-enhancing properties.Through methods such as massage and inhalation,essential oil molecules act on the body to restore visceral balance and promote physical and mental well-being.Aromatherapy in traditional Chinese medicine offers a novel perspective for preventive medicine and is widely applied in treating various symptoms.展开更多
Purpose:This study aims to investigate whether Ganoderma lucidum spore oil(GLSO)could enhance the effect of paclitaxel(PTX),improve the tolerance to PTX and prolong the overall survival of Lewis tumor-bearing mice,whi...Purpose:This study aims to investigate whether Ganoderma lucidum spore oil(GLSO)could enhance the effect of paclitaxel(PTX),improve the tolerance to PTX and prolong the overall survival of Lewis tumor-bearing mice,which has never been reported before.Methods:The tumor,spleen,and thymus were weighed at the end of the experiment.Whole blood was collected for hematological index analysis,and the intact femur was removed to determine the bone marrow nucleated cell count(BMN).The percentage of lymphocytes in the spleen of mice was detected by flow cytometry,the activity of NK cells was detected by LDH assay,and the proliferation index of lymphocytes was determined by CCK-8 assay.The overall and mean survival time and life extension rate were calculated using SPSS software.Results:Our data showed that GLSO could enhance the anti-tumor effect of PTX and prolong the survival of mice.The underlying mechanisms of the above effects might be related to the toxic reduction effect of GLSO by relieving hematotoxicity,myelosuppression and immunosuppression.Specifically,GLSO could increase the number of blood cells and bone marrow cells,alleviate the thymic index,and elevate the number and activity of NK cells in mice treated with PTX.Conclusion:GLSO may enhance the efficacy of PTX by boosting the activity of immune NK cells and prolong survival by counteracting PTX-induced bone marrow alterations and improving hematopoiesis.These findings suggested the promising role of GLSO in combination with PTX to extend the survival and increase the tolerance of patients in clinical chemotherapy of lung cancer.展开更多
目的研究中药挥发油透皮促渗苷类成分效果与对经皮水分散失量(Transepidermal water loss,TEWL)的相关性。方法采用HPLC法测定3种苷类成分(栀子苷、龙胆苦苷、芍药苷)的含量及油水分配系数,采用改良Franz扩散池法以离体SD大鼠腹部皮肤...目的研究中药挥发油透皮促渗苷类成分效果与对经皮水分散失量(Transepidermal water loss,TEWL)的相关性。方法采用HPLC法测定3种苷类成分(栀子苷、龙胆苦苷、芍药苷)的含量及油水分配系数,采用改良Franz扩散池法以离体SD大鼠腹部皮肤为透皮吸收屏障进行体外透皮实验,考察高良姜、干姜、薄荷、胡椒和吴茱萸5种中药挥发油对3种苷类成分的体外透皮促渗效果,采用经皮水分散失量评价5种中药挥发油对大鼠皮肤屏障功能的影响,通过相关性分析考察中药挥发油透皮促渗苷类成分效果与其对皮肤屏障功能影响之间的相关性。结果高良姜油、干姜油、薄荷油、胡椒油能促进3种苷类成分的透皮吸收,也能显著降低大鼠的皮肤屏障功能,相关性分析结果表明中药挥发油对苷类成分的透皮促渗效果与其对皮肤经皮水分散失量的影响显著相关。结论TEWL为中药挥发油透皮促渗剂的快速筛选提供了一种简便快捷的在体评价方法。展开更多
目的探讨中医特色护理在原发性高血压患者中的应用效果。方法选取2019年1月至2020年12月九江市中医医院收治的88例原发性高血压患者作为研究对象,按照随机数字表法分为对照组(44例)和观察组(44例)。两组患者均予以中医中药治疗,对照组...目的探讨中医特色护理在原发性高血压患者中的应用效果。方法选取2019年1月至2020年12月九江市中医医院收治的88例原发性高血压患者作为研究对象,按照随机数字表法分为对照组(44例)和观察组(44例)。两组患者均予以中医中药治疗,对照组采用常规护理,观察组采用中医特色护理,共护理4周。比较两组患者的血压水平[24 h收缩压(24 h SBP)、24 h舒张压(24 h DBP)]、中医症状评分、焦虑抑郁评分及生活质量。结果干预前,两组患者24 h SBP、24 h DBP及中医症状评分、焦虑抑郁评分比较,差异无统计学意义(P>0.05);干预后,两组患者24 h SBP、24 h DBP及中医症状评分、焦虑抑郁评分低于本组干预前,且观察组24 h SBP、24 h DBP及中医症状评分、焦虑抑郁评分低于对照组,差异有统计学意义(P<0.05)。干预前,两组患者生活质量评分比较,差异无统计学意义(P>0.05);干预后,两组患者生活质量评分高于本组干预前,且观察组生活质量评分高于对照组,差异有统计学意义(P<0.05)。结论中医特色护理干预有利于改善原发性高血压患者的血压水平及临床症状,提高生活质量。展开更多
基金Entrepreneurship Training Program for College Students in Nanjing University of Chinese Medicine(Project No.202310315065E)。
文摘Aromatherapy in traditional Chinese medicine integrates the principles of traditional Chinese medicine and Western essential oil therapy,utilizing plant essential oils to regulate qi and blood,unblock meridians,and harmonize emotions.Rosemary essential oil,a commonly used substance,exhibits anti-inflammatory,analgesic,and mood-enhancing properties.Through methods such as massage and inhalation,essential oil molecules act on the body to restore visceral balance and promote physical and mental well-being.Aromatherapy in traditional Chinese medicine offers a novel perspective for preventive medicine and is widely applied in treating various symptoms.
基金Authors of this research are in deep gratitude toward Professor Qin Wang from the Nanchang Research Institute,Sun Yat-sen University for her dedicated guidance and support to this work.This work was supported by the National Key R&D Program of China(2022YFC3500302)the Ministry of Science and Technology of China(No.2017YFC1703104)+1 种基金the Key Laboratory Project of Pharmaceutical Lipids in Guangdong Province(No.2020B1212070024)the Guangdong Province Key Areas R&D Program Project(No.2020B1111120002).
文摘Purpose:This study aims to investigate whether Ganoderma lucidum spore oil(GLSO)could enhance the effect of paclitaxel(PTX),improve the tolerance to PTX and prolong the overall survival of Lewis tumor-bearing mice,which has never been reported before.Methods:The tumor,spleen,and thymus were weighed at the end of the experiment.Whole blood was collected for hematological index analysis,and the intact femur was removed to determine the bone marrow nucleated cell count(BMN).The percentage of lymphocytes in the spleen of mice was detected by flow cytometry,the activity of NK cells was detected by LDH assay,and the proliferation index of lymphocytes was determined by CCK-8 assay.The overall and mean survival time and life extension rate were calculated using SPSS software.Results:Our data showed that GLSO could enhance the anti-tumor effect of PTX and prolong the survival of mice.The underlying mechanisms of the above effects might be related to the toxic reduction effect of GLSO by relieving hematotoxicity,myelosuppression and immunosuppression.Specifically,GLSO could increase the number of blood cells and bone marrow cells,alleviate the thymic index,and elevate the number and activity of NK cells in mice treated with PTX.Conclusion:GLSO may enhance the efficacy of PTX by boosting the activity of immune NK cells and prolong survival by counteracting PTX-induced bone marrow alterations and improving hematopoiesis.These findings suggested the promising role of GLSO in combination with PTX to extend the survival and increase the tolerance of patients in clinical chemotherapy of lung cancer.
文摘目的研究中药挥发油透皮促渗苷类成分效果与对经皮水分散失量(Transepidermal water loss,TEWL)的相关性。方法采用HPLC法测定3种苷类成分(栀子苷、龙胆苦苷、芍药苷)的含量及油水分配系数,采用改良Franz扩散池法以离体SD大鼠腹部皮肤为透皮吸收屏障进行体外透皮实验,考察高良姜、干姜、薄荷、胡椒和吴茱萸5种中药挥发油对3种苷类成分的体外透皮促渗效果,采用经皮水分散失量评价5种中药挥发油对大鼠皮肤屏障功能的影响,通过相关性分析考察中药挥发油透皮促渗苷类成分效果与其对皮肤屏障功能影响之间的相关性。结果高良姜油、干姜油、薄荷油、胡椒油能促进3种苷类成分的透皮吸收,也能显著降低大鼠的皮肤屏障功能,相关性分析结果表明中药挥发油对苷类成分的透皮促渗效果与其对皮肤经皮水分散失量的影响显著相关。结论TEWL为中药挥发油透皮促渗剂的快速筛选提供了一种简便快捷的在体评价方法。
文摘目的探讨中医特色护理在原发性高血压患者中的应用效果。方法选取2019年1月至2020年12月九江市中医医院收治的88例原发性高血压患者作为研究对象,按照随机数字表法分为对照组(44例)和观察组(44例)。两组患者均予以中医中药治疗,对照组采用常规护理,观察组采用中医特色护理,共护理4周。比较两组患者的血压水平[24 h收缩压(24 h SBP)、24 h舒张压(24 h DBP)]、中医症状评分、焦虑抑郁评分及生活质量。结果干预前,两组患者24 h SBP、24 h DBP及中医症状评分、焦虑抑郁评分比较,差异无统计学意义(P>0.05);干预后,两组患者24 h SBP、24 h DBP及中医症状评分、焦虑抑郁评分低于本组干预前,且观察组24 h SBP、24 h DBP及中医症状评分、焦虑抑郁评分低于对照组,差异有统计学意义(P<0.05)。干预前,两组患者生活质量评分比较,差异无统计学意义(P>0.05);干预后,两组患者生活质量评分高于本组干预前,且观察组生活质量评分高于对照组,差异有统计学意义(P<0.05)。结论中医特色护理干预有利于改善原发性高血压患者的血压水平及临床症状,提高生活质量。
