Motivated by the work of Birman about the relationship between mapping class groups and braid groups,the authors discuss the relationship between the orbit braid group and the equivariant mapping class group on the cl...Motivated by the work of Birman about the relationship between mapping class groups and braid groups,the authors discuss the relationship between the orbit braid group and the equivariant mapping class group on the closed surface M with a free and proper group action in this paper.Their construction is based on the exact sequence given by the fibration F_(0)^(G) M→F(M/G,n).The conclusion is closely connected with the braid group of the quotient space.Comparing with the situation without the group action,there is a big difference when the quotient space is T^(2).展开更多
Background Finding methods to judge the quality of X-ray crystallographic information is an active research topic.The quality of electron density maps reconstructed by Fourier transform is always limited by the finite...Background Finding methods to judge the quality of X-ray crystallographic information is an active research topic.The quality of electron density maps reconstructed by Fourier transform is always limited by the finite resolution,the amplitude/phase error and the completeness of diffraction data.At present,the R value and effective resolution are common ways of evaluating the quality of electron density maps.Unfortunately,the current evaluation methods are only dependent on diffraction amplitude,without any phase information.Methods Advanced evaluation functions in real space are designed to estimate the electron density map quality.The electron density map definition evaluation function relies on the atomicity of the electron density distribution.We use the power spectrum electron density entropy in protein crystallography for the first time.These two functions include both structure factor amplitudes and phases via the Fourier transform of electron density map.Results We carry out tests on synthetic data sets of known structures,varying the resolution and error,and draw the quality curves of electron density maps with theoretical,noisy and experimental diffraction data by two evaluation functions at different resolutions.The curves reveal the optimum structure and resolution of proteins clearly.Conclusions The work presented here offers new methods to evaluate the qualities of the electron density maps of proteins with slight differences,and brand new indicators to select the optimum diffraction resolution of protein structures.展开更多
基金supported by the National Natural Science Foundation of China(No.11971112)。
文摘Motivated by the work of Birman about the relationship between mapping class groups and braid groups,the authors discuss the relationship between the orbit braid group and the equivariant mapping class group on the closed surface M with a free and proper group action in this paper.Their construction is based on the exact sequence given by the fibration F_(0)^(G) M→F(M/G,n).The conclusion is closely connected with the braid group of the quotient space.Comparing with the situation without the group action,there is a big difference when the quotient space is T^(2).
基金This work was financially supported by grants from the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB08030103)the National Natural Science Foundation of China(31570744)the National Key Research and Development Project(2017YFA0504900).
文摘Background Finding methods to judge the quality of X-ray crystallographic information is an active research topic.The quality of electron density maps reconstructed by Fourier transform is always limited by the finite resolution,the amplitude/phase error and the completeness of diffraction data.At present,the R value and effective resolution are common ways of evaluating the quality of electron density maps.Unfortunately,the current evaluation methods are only dependent on diffraction amplitude,without any phase information.Methods Advanced evaluation functions in real space are designed to estimate the electron density map quality.The electron density map definition evaluation function relies on the atomicity of the electron density distribution.We use the power spectrum electron density entropy in protein crystallography for the first time.These two functions include both structure factor amplitudes and phases via the Fourier transform of electron density map.Results We carry out tests on synthetic data sets of known structures,varying the resolution and error,and draw the quality curves of electron density maps with theoretical,noisy and experimental diffraction data by two evaluation functions at different resolutions.The curves reveal the optimum structure and resolution of proteins clearly.Conclusions The work presented here offers new methods to evaluate the qualities of the electron density maps of proteins with slight differences,and brand new indicators to select the optimum diffraction resolution of protein structures.
