Research on Corporate Social Responsibility Evaluation Based on Improved CRITIC-TOPSIS—A Case Study of Listed Companies in China’s Pharmaceutical Distribution Industry

Corporate social responsibility (CSR) has garnered considerable attention from countries, institutions, enterprises and social groups. However, the lack of research on CSR evaluation system for industries has impeded its development and construction across various industries. Therefore, given the close association of pharmaceutical distribution enterprises with personal health, there exists a pressing need to explore the CSR in this domain. This paper establishes a CSR evaluation index system for pharmaceutical distribution enterprises, employing a combination of documentary analysis and in-depth interviews. This index system comprises 7 CSR criterion layers (e.g., responsible governance and employee responsibility) and 56 index layers. 25 listed companies in China’s pharmaceutical distribution industry are chosen as research objects, and this study also establishes an evaluation model for the CSR of pharmaceutical distribution companies through the improved Criteria Importance Though Intercrieria Correlation (CRITIC) method combined with The Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) method. The empirical analysis reveals that the responsible governance criterion layer and the social development criterion layer demonstrate the best performance, while the supplier, customer and patient responsibility criterion layer exhibit the worst performance.

In-vitro digestibility,protein digestibility corrected amino acid,and sensory properties of banana-cassava gluten-free pasta with soy protein isolate and egg white protein addition

Soy protein isolate and egg white protein were added to cassava-banana gluten-free pasta and the effects on the nutritional quality,digestibility properties,protein digestibility corrected amino acid(PDCAA),and sensory acceptance of the pasta was observed.Banana-cassava composite flour(75:25)was blended with soy protein isolate or egg white protein at the following rates:0,5,10,and 15 g/100 g flour.Cooked pasta samples were analysed for total phenolic content(TPC),antioxidant activity,amino acid profiles,protein content,starch digestibility,protein digestibility and protein digestibility corrected amino acid score(PDCAAS).Addition of both proteins decreased starch digestibility,increased protein digestibility,improved the balance of the amino acid profile,and PDCAAS whereas only soy protein isolate enhanced the TPC and antioxidant capacity of the banana-cassava pasta.An egg white protein-fortified banana-cassava pasta had better customer acceptance and purchase intent than soy protein isolate inclusion.

COMPREHENSIVE EVALUATION OF FAULT-TOLERANT PROPERTIES OF REDUNDANT ROBOTS

When a redundant robot performs a fault-tolerant operation for locked joint failures, its fault tolerant properties should include dexterity and sudden change of joint velocity at the moment of locking failed joints and the dexterity during the post-failure. Firstly three fault-tolerant indexes, reduced condition number, sudden change of relative joint velocity and centrality are proposed, which can comprehensively evaluate the kinematical performance of a redundant robot during its entire fault-tolerant operations. Then, the influence of the initial postures of robot＇s end-effector on these fault-tolerant indexes is analyzed with a planar robot and a spatial robot. Simulation results show that for a given task the joint trajectory with the best comprehensive effect of fault tolerance can be determined by optimizing the initial posture of a robot.

Evaluation on Soil Improvement Effects of Organic Fertilization in Honey Peach Orchard in the Longquan Mountain

Combined application of organic fertilizer is an effective measure to improve the productivity and ecological effect of newly added soil.However,the effect of organic fertilizer application in newly added orchard soil is not clear.In this project,the soil of newly built peach orchard in the Longquan Mountain of Chengdu was applied with 45 t/hm 2 of organic fertilizer.After 9 months of planting 6 varieties of honey peach(Wanhujing,Baifeng,Zhongtao 13,Huangjinmitao 1,Zhongpan 101,Zhongpan 104),the locally well developed peach orchard was taken as the control.The physical and chemical properties of soil from four topography(top slope,middle slope,lower slope and flat land)of newly built peach orchard were analyzed,and the effect of organic fertilizer on soil was evaluated.The results showed that combined application of organic fertilizer had different effects on soils from orchards with different varieties of peach and from different terrain parts of the same peach variety.Specifically,it had the best effect on soil improvement in Baifeng(local variety),Zhongpan 101 and Zhongpan 104(introduced varieties).Meanwhile,the best effect of soil improvement was found on top slope.Cluster analysis divided newly built peach orchards,uncultivated soil,and locally well developed peach orchard into four groups,indicating that the selected amount of organic fertilizer application in this study has improved the soil of peach orchards to some extent,but it was still necessary to increase the application amount.It was better for 54 t/hm 2 amount of organic fertilization on the part of top and middle slope,and 60 t/hm 2 on the lower slope and flat land.The comprehensive ecological benefit assessment of organic fertilizer should be conducted based on long-term monitoring of peach orchard ecological environment,fruit tree growth,fruit yield and quality,which would provide scientific basis for peach orchard production and management.

Nutritional evaluation,fatty acid analysis and anticancer properties investigation of seeds from kan-zaw,a potential diet oil and medicinal plant

Payenapara lleloneura Kurz.(Kan-zaw),an endemic medicinal plant only found in Tanintharyi Region of Myanmar,is widely used in the treatment of various cancer and different ailments.In the present research,the seeds were phytochemical investigated for their nutritional potential for their use as functional foods or novel diet oil resources.Nutritional evaluation showed that the seeds are rich in fats and carbohydrates(soluble sugars and starch).Fatty acid analyses showed that the seeds accumulate very richα-eleostearic acid(α-ESA,18:3^(Δ9 cis,11-trans),13 trans),an important conjugated fatty acid,up to more than 70% of total fatty acids.The seed oil derived from the Kan-zaw tree contains approximately 3.25% β-eleostearic acid(18:3^(Δ9 trans,11 trans,13 trans)),an unusual conjugated fatty acid that imparts a potent anticancer application and industrially important drying qualities to Kan-zaw oil.Physicochemical properties of the Kan-zaw seeds were examined;petroleum ether(60–90℃)extract of seed oils were also investigated for the saponification value,iodine value and estimation of acid value.Further,the present study investigated cytotoxic potential of ethanol,methanol,acetone,chloroform Kan-zaw seed extracts and commercial Kan-zaw oil against human cervical cancer cell line(HeLa).The Kan-zaw extracts and oil have shown significant anticancer activity on HeLa cells.

Study on the Quality Evaluation of Steamed Bread and the Physical and Chemical Properties of Wheat

In this study,the different physical and chemical properties of wheat were studied,and on this basis,and the quality of steamed bread made was evaluated.We analyzed the correlation between the evaluation indexes of steamed bread and the basic physical and chemical indexes of wheat,and investigated important factors that affect the evaluation indexes of steamed bread,including flour extraction rate,protein content,amylose content,protein,added amount of yeast,fermentation time and other aspects.According to the study results,it was shown that different factors had different effect on steamed bread quality,with both positive correlation and negative correlation.

Research on Problems and Countermeasures of Patent Evaluation System in Pharmaceutical Enterprises

Objective To provide some suggestions and countermeasures for improving the patent evaluation system in pharmaceutical enterprises.Methods Literature research method was used to collect the relevant documents of pharmaceutical enterprises and patent evaluation system,and then the problems of traditional patent evaluation methods for pharmaceutical patents were studied.Results and Conclusion The evaluation of pharmaceutical patents plays an important role for pharmaceutical enterprises.However,it is urgent to improve the pharmaceutical patent evaluation system because there are many difficulties in evaluating pharmaceutical patents,such as large fluctuation of patent value,strong subjective interference,the incomplete pharmaceutical information,unapplicable traditional evaluation method,and the insufficient role of evaluation agencies.Therefore,some suggestions are put forward:(1)The application of the real option method;(2)Developing evaluation institutions and training evaluation personnel;(3)Improving the laws and policies related to the evaluation of pharmaceutical patents;(4)Building a pharmaceutical patent evaluation database.

The Impact of Generic Drug Consistency Evaluation Policy on Pharmaceutical Enterprises

Objective To study the impact of consistency evaluation policy on pharmaceutical enterprises from four aspects:reference preparations,evaluation methods,input costs,and market competitions,and government incentives for generic drug manufacturers,so as to put forward relevant suggestions.Methods Literature research method and statistical analysis method were used to provide data support for paper writing,making suggestions,and enhancing the predictability of policy.Results and Conclusion Some pharmaceutical enterprises faced difficulties in obtaining reference preparations,high input costs for exploring evaluation methods,and greater market competition.Consistency evaluation is a key measure to comprehensively improve the quality and efficacy of generic drugs.However,difficulties in obtaining reference preparations,high input costs and complex evaluation methods all affect the enthusiasm of companies.Therefore,national and local regulatory agencies have issued some supporting policies,which should be improved to assist enterprises in conducting consistency evaluations.

Empirical Analysis on Performance Evaluation of A Pharmaceutical Company Based on Economic Value Added

Objective To establish an economic value added(EVA)performance evaluation system to maintain the competitiveness of pharmaceutical company A under the environment of fierce competition in the pharmaceutical industry.Methods An EVA performance evaluation model was established by adjusting the items of EVA performance evaluation index,such as after-tax profits,total invested capital and weighted average cost of capital rate.Results and Conclusion EVA values of pharmaceutical company A from 2014 to 2018 were calculated and compared with the traditional performance evaluation method,it was found that EVA performance evaluation model reflected the real performance of pharmaceutical company A.Therefore,pharmaceutical company A is doing well,but its growth rate is unstable.

Evaluation of properties for lubricant filter in diesel engines

The properties of lubricant filters in diesel engines directly affect operation of the lubricant system, and lubricant filters are apt to be impacted by many factors. Therefore, scientific and sensible methods evaluating the properties for lubricant filter diesel engines are necessary to monitor filter properties on line and dynamically. This paper applies ferrographic techniques and adopts sampling methods that oil specimens are synchronously obtained in front of and behind filter elements to monitor the filters of ISUZU DA-220 diesel engine in two FD50 forklifts. Results show that the combination of ferrographic techniques and above sampling methods is effective in analyzing the whole operating process of filters used in diesel engines. The service life and ruined type of filter can be estimated through the relationship between ferrographic readings in front and behind of filter and operation time. Furthermore, through a great deal of tests, a series of experimental curves of readings and time and characteristic parameters for filters used in different machines can be gained, which has guiding significance to the selection and maintenance of the filters. But because of the limitation of the ferrographic technique, the debris on the substrate prevents determination of sizes. It is difficult to judge accurately the size of debris that a filter can filter.

Evaluation of myocardial viability during cold storage by measurement of myocardual dielectric properties tanδm in radio frequency

Objective To study the mechanism of myocardial dielectric property changes in radio frequency during hypothermic preservation and explore myocardial viability evaluative method. Methods Hybrid young pigs ( 20 - 30 kg) were used in the experiment. Heart arrest was in-

Fracability Evaluation of Shale of the Wufeng-Longmaxi Formation in the Changning Area, Sichuan Basin

The fracturing technology for shale gas reservoir is the key to the development of shale gas industrialization.It makes much sense to study the mechanical properties and deformation characteristics of shale,due to its close relationship with the fracability of shale gas reservoir.This paper took marine shale in the Changning area,southern Sichuan Basin of China as the research object.Based on field profile and hand specimen observation,we analyzed the development of natural fractures and collected samples from Wufeng Formation and Longmaxi Formation.Combining with the indoor experiment,we investigated the macroscopic and microscopic structural features and the remarkable heterogeneity of shale samples.Then we illustrated the mechanics and deformation characteristics of shale,through uniaxial compression test and direct shear test.The shale has two types of fracture modes,which depend on the angular relation between loading direction and the bedding plane.Besides,the Wufeng shale has a higher value of brittleness index than the Longmaxi shale,which was calculated using two methods,mechanical parameters and mineral composition.Given the above results,we proposed a fracability evaluation model for shale gas reservoir using the analytic hierarchy process.Four influence factors,brittleness index,fracture toughness,natural fractures and cohesive force,are considered.Finally,under the control of normalized value and weight coefficient of each influence factor,the calculations results indicate that the fracability index of the Wufeng Formation is higher than that of the Longmaxi Formation in Changning area,southern Sichuan Basin.

Effects of High Pressure on the Textural and Sensory Properties of Minced Fish Meat Gels for the Dysphagia Diet

A new product of minced fish meat with high pressurization was produced for individuals with difficulties in mastication and swallowing and for elderly people on a dysphagia diet. Minced fish meat was added to distilled water at ratios of 1:0.5, 1:1 and 1:1.5 by mixing with 1.5% NaCl. Half of the samples were modified by heating (H-gels) and half by high pressure at 400 MPa for 20 min (P-gels). The hardness of the H- and P-gels was 0.97 to 2.83 [×104 N/m2] and 2.25 to 10.03 [×104 N/m2], respectively. For SDS-PAGE analysis, low-molecular-weight proteins in the P-gel were released more easily than those in the H-gel by the difference in gel formation, which is related to the detection of α-actinin in the supernatant of pressurized actomyosin. The ultrastructural observations showed a regular filamentous network structure in the P-gel. For the sensory evaluation, the P-gels were determined to be more lustrous, juicier, more moderately elastic and smoother. These gels conformed to the criteria of Dietary Uses for Dyspahgic Patients and Japanese Dysphagia Diet 2013. High pressure treatment denatured the protein composition of the minced fish meat gel, which led to a clearer three-dimensional network structure. High pressure made it possible to form minced fish meat gels with a low salt concentration. Obtained minced fish meat gels were improved in textural properties by addition of water and under high pressure, which were different from the ones by traditional heating. Improvement in textural properties will raise the sensory evaluation for elderly and dysphagic people. It is expected that the pressurized gels will be practical for a dysphagia diet.

Analytical Evaluation of Component Activity of Ca-Si-Al System

The excess partial molar Gibbs energy of Ca in the CaSiAl ternary system was expressed as a polynome, then the coefficients Ajk involved in the polynome were determined mainly based on the boundary data of the ternary alloy with the least-square method. The coefficients Fjk contained in the polynomial of excess molar Gibbs energy of the alloy were determined in the light of Gibbs-Duhem Equation. The polynomial expression of the excess partial molar Gibbs energy of Si and Al, in which the known Ajk and Fjk were involved, was derived according to the modified I-D means. All of the evaluated component activities of the alloy are available in the whole composition range. The results show a good agreement with the experimental data.

Statistical Analysis of the Asphalt Mixtures Volumetric Properties

Based on statistics principle,random error and systematic error were considered and the volumetric properties of the two mixtures types,namely A and B,were statistically analyzed using different distribution methods.Seventy-two samples of mixture A and fifty-two of mixture B were fabricated using the Marshall method.The probability distributions were compared on the basis of goodness of fit.Weibull model was found to be most appropriate model for describing the asphalt mixtures volumetric properties distribution.The two-parameter Weibull distribution function applied well to model the bulk specific gravity and voids filled with asphalt data,whereas,the three-parameter Weibull distribution appeared to be more appropriate in the discussing of air voids and voids in mineral aggregate.The experimetal results is revealed that compared with the mean value,the peak value of Weibull distribution was suggested as an alternative and more powerful parameter for describing the test data distribution characteristic.The analysis of test results also revealed that there were significant differences in the volumetric properties of the two tested mixtures for the same confidence level.The confidence interval decreased with the decreasing in reliability.

Elevated-temperature mechanical properties and thermal stability of Al-Cu-Mg-Ag heat-resistant alloy

The elevated-temperature mechanical properties and thermal stability of Al-Cu-Mg-Ag heat-resistant alloy were studied by tensile test, transmission electron microscopy(TEM) and scanning electron microscopy(SEM), respectively. The results show that with the increase of Ag content, the tensile strength and yield strength increase, which is attributed to the increase of the precipitations number and the decrease of the size. The same conclusions are drawn in the study of increasing Mg content. The alloy possesses excellent thermal stability. At 100-150 °C, the strength of the under-aged alloy increases at the initial stage, and after reaching the peak strength, it remains the same. The secondary precipitation of the under-aged alloy occurs in the process of exposure at 150℃, and it distributes diffusely after thermal exposed for 20 h. Then, the tensile strength decreases gradually with increasing the thermal exposure time at 200-250 °C. The strength of the peak-aged alloy decreases gradually, and the precipitation grows up, but the number decreases gradually with prolonging the exposure time at 100-250 °C. The strength of two kinds of alloys decreases with elevating of exposure temperature.

Quantitative characterization of cell physiological state based on dynamical cell mechanics for drug efficacy indication

Cell mechanics is essential to cell development and function,and its dynamics evolution reflects the physiological state of cells.Here,we investigate the dynamical mechanical properties of single cells under various drug conditions,and present two mathematical approaches to quantitatively characterizing the cell physiological state.It is demonstrated that the cellular mechanical properties upon the drug action increase over time and tend to saturate,and can be mathematically characterized by a linear timeinvariant dynamical model.It is shown that the transition matrices of dynamical cell systems significantly improve the classification accuracies of the cells under different drug actions.Furthermore,it is revealed that there exists a positive linear correlation between the cytoskeleton density and the cellular mechanical properties,and the physiological state of a cell in terms of its cytoskeleton density can be predicted from its mechanical properties by a linear regression model.This study builds a relationship between the cellular mechanical properties and the cellular physiological state,adding information for evaluating drug efficacy.

New Trends in Non-Destructive Evaluation of Surface Hardened Layers and Coatings

This article should not be considered as a full review of current methods for non-destructive testing of surface layers. Rather, it is a subjective in this area. However, the article provides some review of the challenges posed by the current state of surface layers treatment techniques on the area of Non-Destructive materials evaluation: enhancement of the sensitivity to the type of defects, increasing resolution to submicron values, the requirement to diagnose the surface layers with depth resolution of properties, diagnosis of multilayer multicomponent surface layers and coatings, treated with concentrated energy.

Study of Material Evaluation Probe Using a Longitudinal Wave and a Transverse Wave

Transmitting a longitudinal wave and a traverse wave into a composite material in a molten state has been studied in the online control of the composite material which cannot be evaluated by a conventional ultrasonic sensor as a final analysis, using the difference in the propagation characteristics of both modes. It is especially expected that measurement of the physical quantity which was not able to be conventionally measured can be performed by carrying out coincidence measurement of the ultrasonic wave in both modes. Therefore, in this research study, an ultrasonic probe, which can simultaneously transmit and receive a longitudinal wave and a traverse wave has been developed using an electromagnetic acoustic transducer (EMAT) because it has the advantage of measuring high temperature samples. In this study, two methods have been compared. The 1st method uses a traverse wave EMAT that travels in a vertical direction and a bar wave by which the low order mode is equivalent to longitudinal wave vibration. The other method is to carry out the mode conversion of the traverse wave by a traverse wave-EMAT. The longitudinal converted from the transverse wave are spread in the axis direction. As the experimental results of both optimizations of the drive conditions, it has been confirmed that the 2nd mode conversion method was promising. This paper reports about the trial process and the experimental results.