This paper reviews and adds to previous arguments for the thesis that Karl Popper was mistaken to have rejected hypothetico-deductive confirmation. By turning from the positive idea of verification to the negative ide...This paper reviews and adds to previous arguments for the thesis that Karl Popper was mistaken to have rejected hypothetico-deductive confirmation. By turning from the positive idea of verification to the negative idea of criticism, Popper believed that he had turned his back on induction. He believed he had ＂solved＂ the ＂problem of induction＂ by providing a non-inductive account of corroboration. Popper used the term ＂corroboration＂ rather than confirmation which he believed was too closely allied to the notion of the inductive or probabilistic support that a theory can receive from evidence. Wesley Salmon＇s （1967） ＂concept of confirming evidence＂ and Clark Glymour＇s （1980） ＂bootstrap conception of evidence for theory＂ both defended respectively the thesis that passed tests can be confirmed by evidence or warranted by the degree of probability. Using a sequence of symbols in logical form or analysis, I shall further defend the concept to hypothetico-deductive confirmation in order to show that the known weaknesses of Popper＇s critical rationalism are remediable, once the notion of evidence for theories is brought back into consideration.展开更多
The EVIDENCE trial demonstrated that interferon (IFN)beta-1a, 44 mcg subcutaneously (sc) three times weekly (tiw) (Rebif), was significantly more effective than IFN beta-1a, 30 mcg intramuscularly (im) once weekly (...The EVIDENCE trial demonstrated that interferon (IFN)beta-1a, 44 mcg subcutaneously (sc) three times weekly (tiw) (Rebif), was significantly more effective than IFN beta-1a, 30 mcg intramuscularly (im) once weekly (qw) (Avonex), in reducing relapses and magnetic resonance imaging (MRI)activity in patients with relapsing-remitting multiple sclerosis at both 24 and 48 weeks of therapy. We now present final comparative data on these patients, showing that the superior efficacy of IFN beta-1a, 44 mcg sc tiw, for relapse measures and MRI activity, compared with IFN beta-1a, 30 mcg im qw, was sustained for at least 16 months. The development of antibodies to IFN was associated with reduced efficacy on MRI measures and fewer IFN-related adverse events, but did not have an impact on relapse outcomes.展开更多
Amoxicillin is a kind of β-lactam antibacterial.It has been widely used in clinic.Recently,some products of amoxicillin were found to be unqualified in content and acidity.In this paper,the quality of amoxicillin wer...Amoxicillin is a kind of β-lactam antibacterial.It has been widely used in clinic.Recently,some products of amoxicillin were found to be unqualified in content and acidity.In this paper,the quality of amoxicillin were firstly analyzed by using FT-ICR-MS and FT-ICR-MS/MS method by comparing the accurate relative molecular mass of amoxicillin fragmentation and its accurate mass obtained.展开更多
文摘This paper reviews and adds to previous arguments for the thesis that Karl Popper was mistaken to have rejected hypothetico-deductive confirmation. By turning from the positive idea of verification to the negative idea of criticism, Popper believed that he had turned his back on induction. He believed he had ＂solved＂ the ＂problem of induction＂ by providing a non-inductive account of corroboration. Popper used the term ＂corroboration＂ rather than confirmation which he believed was too closely allied to the notion of the inductive or probabilistic support that a theory can receive from evidence. Wesley Salmon＇s （1967） ＂concept of confirming evidence＂ and Clark Glymour＇s （1980） ＂bootstrap conception of evidence for theory＂ both defended respectively the thesis that passed tests can be confirmed by evidence or warranted by the degree of probability. Using a sequence of symbols in logical form or analysis, I shall further defend the concept to hypothetico-deductive confirmation in order to show that the known weaknesses of Popper＇s critical rationalism are remediable, once the notion of evidence for theories is brought back into consideration.
文摘The EVIDENCE trial demonstrated that interferon (IFN)beta-1a, 44 mcg subcutaneously (sc) three times weekly (tiw) (Rebif), was significantly more effective than IFN beta-1a, 30 mcg intramuscularly (im) once weekly (qw) (Avonex), in reducing relapses and magnetic resonance imaging (MRI)activity in patients with relapsing-remitting multiple sclerosis at both 24 and 48 weeks of therapy. We now present final comparative data on these patients, showing that the superior efficacy of IFN beta-1a, 44 mcg sc tiw, for relapse measures and MRI activity, compared with IFN beta-1a, 30 mcg im qw, was sustained for at least 16 months. The development of antibodies to IFN was associated with reduced efficacy on MRI measures and fewer IFN-related adverse events, but did not have an impact on relapse outcomes.
文摘Amoxicillin is a kind of β-lactam antibacterial.It has been widely used in clinic.Recently,some products of amoxicillin were found to be unqualified in content and acidity.In this paper,the quality of amoxicillin were firstly analyzed by using FT-ICR-MS and FT-ICR-MS/MS method by comparing the accurate relative molecular mass of amoxicillin fragmentation and its accurate mass obtained.
