低渗透设计GORE EXCLUDER覆膜支架在复杂腹主动脉瘤腔内治疗中的应用

目的评价低渗透设计GORE EXCLUDER覆膜支架腔内治疗复杂腹主动脉瘤的安全性和有效性。方法 2011年4月—2014年4月应用低渗透设计GORE EXCLUDER覆膜支架腔内治疗复杂腹主动脉瘤21例,收集患者资料并进行回顾性分析。结果 21例患者中,男19例,女2例;年龄55~87岁,中位数为72.34岁。本组病例存在以下1种或多种情况：合并髂动脉瘤10例,巨大动脉瘤4例,短瘤颈3例,瘤颈严重扭曲3例,入路严重扭曲4例,股动脉纤细1例,附壁血栓和严重钙化6例。21例手术均获成功,无中转开腹及术中死亡病例,2例术后住院期间死于合并症。手术时间（135.43±12.45）min,术中出血量为（180.24±21.66）m L,均无输血。术中Ⅰ型内漏5例,Ⅱ型内漏3例,Ⅲ型内漏2例,均术中处理满意。术后随访19例,随访时间为3~36个月,18例存活,1例死于糖尿病并发症。随访患者术后均复查CT血管造影,未发现与支架相关的并发症。结论低渗透设计GORE EXCLUDER覆膜支架腔内修复适用于多数复杂腹主动脉瘤患者的治疗,手术风险较低,术中和术后并发症较少,具有良好的安全性和有效性。

GORE EXCLUDER覆膜支架在腹主动脉瘤腔内修复术中的临床应用

目的：探讨GORE EXCLUDER覆膜支架腔内修复治疗腹主动脉瘤的疗效.方法：回顾性分析自2012年1月至2013年5月,采用GORE EXCLUDER覆膜支架行腹主动脉瘤腔内修复术的21例患者,其中男性19例,女性2例,年龄48 ～ 84岁,平均（68.9±9.9）岁.21例均为肾下型腹主动脉瘤,术后1,3,6及12个月之后,每年行主动脉CTA复查.结果：21例均成功置入GORE EXCLUDER覆膜支架,技术成功率100％；共置入主体覆膜支架21枚,对侧分支支架21枚,延长支6枚,Cuff支架1枚.主体覆膜支架直径23 ～31 mm,长度为120 ～ 180 mm,平均（152-±20.7）mm; 16例封闭一侧髂内动脉,5例保留双侧髂内动脉.围手术期无死亡病例及严重并发症发生；随访3 ～15个月,未见支架移位及内漏发生.结论：GORE EXCLUDER腔内修复肾下腹主动脉瘤近、中期效果良好.

倒装Gore Excluder对侧喇叭腿支架治疗孤立性髂动脉瘤1例

患者,男性,77岁。因＂突发胸背部疼痛1天＂于2017年3月8日入住我院心血管内科,入院后行全主动脉CT血管造影（computed tomography angiography,CTA）显示：胸主动脉弓降部小弯侧溃疡;左髂总动脉瘤（瘤体最大直径40 mm,近端髂总动脉瘤颈直径16 mm、长度15 mm,远端髂外动脉直径12 mm）（图1）。于2017年3月14日,气管插管全麻下行胸主动脉溃疡腔内隔绝＋左锁骨下动脉烟囱支架植入＋左髂内动脉栓塞＋左髂动脉腔内隔绝（倒装Gore Excluder对侧喇叭腿支架）术。

应用覆膜支架台上开窗治疗短瘤颈腹主动脉瘤1例

腹主动脉瘤（abdominal aortic aneurysm,AAA）是指腹主动脉呈瘤样扩张,直径增大50%以上定义为动脉瘤。目前,AAA腔内修复术（endovascular aneurysm repair,EVAR）已广泛应用于AAA的治疗,其特点是创伤和痛苦小,术后恢复快,手术期并发症的发生率和病死率低,尤其对一些有严重合并症、对传统开腹血管重建手术耐受性差的患者提供了治愈机会[1]。但符合传统EVAR标准解剖结构的AAA仅占总数的20%~50%[2]。

氢化物发生技术和ICP-AES联用的前景

Hydride generation (HG)technique has been widely used for the determination of volatile hydride forming elements by atomic spectroscopy since Holak reported the determination of arsenic with this technique using atomic absorption spectrometry in 1969. The most commonly used

Phytoremediation Potential of Indigenous Plants Growing at Nchanga Mine in Chingola, Zambia

Mining and smelting processes are among the key sources of soil contamination by heavy metals resulting in dramatic disturbances and loss of biodiversity. Native plants growing naturally in hostile mining environments can be used for management, decontamination and possible rehabilitation of polluted soils. These plants are either excluders or accumulators based on their Bioaccumulation Factors (BAF). This, therefore requires identification of native plants that are able to accumulate heavy metals in their plant tissues at concentrations higher than that in the soil in which they are growing. This study investigated the phytoremediation potential of indigenous plants growing at the tailings dams of Nchanga Mine in Chingola, Zambia. TD4 and a site 50 m away from TD4 were sampled as Sampling Areas One (1) and Two (2), respectively. TD4 was divided into four quadrants and three plots from each quadrant were randomly sampled. Three plots from each of the two quadrants from Sampling Area Two were also sampled. Composite soil samples were collected from the plots and a total of 175 individuals of 16 grass and herbaceous plant species were collected and analysed. Atomic Absorption Spectrophotometry was used to determine the concentrations of Copper (Cu) and Zinc (Zn) in the soils and plant specimens. The findings of the study showed that the concentrations of Cu and Zn in the soil ranged from 891.41 mg/kg to 15,617.47 mg/kg and 20.73 mg/kg to 96.85 mg/kg, respectively. Arthraxonquartinianus had the highest concentration of Cu (1016.8 mg/kg) while Cyperusrotundus had the lowest (29.35 mg/kg). Arthraxonquartinianus had the highest concentration of Zn (192.8 mg/kg) and Crinum had the lowest (28.24 mg/kg). BAF values for Cu were less than 1 in all the plants and BAF values for Zn were highest in Arthraxonquartinianus (10.77) with Crinum having the lowest BAF of 0.01. The Bioaccumulation Factors indicated that all the plant species studied are Cu excluders;and with the exception of Crinum, all were Zn accumulators and Arthraxonquartinianus, a hyperaccumulator of Zn.

A NEW SPECIFIC NAME IN THE GENUS GRACILARIA

The red alga Gracilaria heteroclada was established by the authors (Zhang Junfu and Xia Bangmei, 1988). The specific name is, however, illegitimatized by the earlier homonym Gracilaria heteroclada (Montagne) (J. et G. Feldmann,1943). In 1989, Fredeficq and Hommersand restored the genus Gracilariopsis with its type species, G. lemaneiformis, thus excluding it (Gracilaria heteroclada Zhang et Xia) from the genus Gracilaria. It was transferred to Gracilariopsis

CLINICAL OBSERVATION ON OSTEOPOROSIS TREATED WITH TRADITIONAL KIDNEY-TONIFYING MEDICAMENTS

The method of scoring kidney deficiency symptoms and bone density was used to judge therapeutic efficacy on osteoporosis of traditional kidney-tonifying drugs. It was proved that the drugs not only improved clinical symptoms but also delayed the developmental pro-cess of this disorder. It also verified the correctness of the traditional theory that the kidney dominates the bone and generates the marrow.

CLINICAL OBSERVATION ON ACUPUNCTURE TRETMENT OF UROSCHESIS

Uroschesis is manifested by. incompleteness or difficulty in urination or even incapability of urination. Clinically, the symptoms include retention of urine and anuria induced by a variety of causes. In this study, the patients with anuria or oliguria due to lesions of renal parenchyma or renal failure were excluded. Using acupuncture, the author had treated 36 cases of functional uroshesis with satisfactory results as reported in the following.

Problem of living liver donation in the absence of deceased liver transplantation program:Mansoura experience

We report our experience with potential donors for living donor liver transplantation(LDLT), which is the first report from an area where there is no legalized deceased donation program. This is a single center retrospective analysis of potential living donors(n = 1004) between May 2004 and December 2012. This report focuses on the analysis of causes, duration, cost, and various implications of donor exclusion(n = 792).Most of the transplant candidates(82.3%) had an experience with more than one excluded donor(median = 3). Some recipients travelled abroad for a deceased donor transplant(n = 12) and some died before finding a suitable donor(n = 14). The evaluation of an excluded donor is a time-consuming process(median = 3 d, range 1 d to 47 d). It is also a costly process with a median cost of approximately 70 USD(range 35 USD to 885 USD). From these results, living donor exclusion has negative implications on the patients and transplant program with ethical dilemmas and an economic impact. Many strategies are adopted by other centers to expand the donor pool; however, they are not all applicable in our locality. We conclude that an active legalized deceased donor transplantation program is necessary to overcome the shortage of available liver grafts in Egypt.

Excluded Volumes of Anisotropic Convex Particles in Heterogeneous Media:Theoretical and Numerical Studies

Understanding the excluded volume of anisotropic particle is of great importance in the evaluation of continuum percolation and random packing behaviors of soft/hard particle systems in heterogeneous disordered media.In this work,we obtain the excluded volumes of several anisotropic convex particles including prolate spheroids,oblate spheroids,spherocylinders,and Platonic particles,using theoretical and numerical approaches.According to the second virial coefficient,we first present a theoretical scheme for determining the excluded volumes of anisotropic particles.Also,the mean tangent diameters of anisotropic convex particles are formulated by the quantitative stereology.Subsequently,Monte Carlo simulations are demonstrated to numerically evaluate the excluded volumes.The theoretical results of the dimensionless excluded volume are thereafter compared with that of the numerical results to verify the validity of the theoretical scheme.We further investigate the dependence of the dimensionless excluded volume on the geometric characteristics of anisotropic particles based on the proposed theoretical and numerical schemes.Results show that the dimensionless excluded volume mainly relies on the shape and surface information of anisotropic particles.The developed theoretical and numerical schemes can provide theoretical insights into the percolation threshold and packing density of soft/hard anisotropic particle systems in heterogeneous materials,physics,and chemistry fields.

China's meat and grain imports during 2000–2012 and beyond: A comparative perspective

This paper provides a review on China＇s meat trade for the 2000–2012 period and discusses its future development, with reference to China＇s grain trade. With marginal decreases in meat exports and slight increases in their imports, China＇s net imports of major meat products（including pork, beef, mutton and poultry but excluding meat offal） were just below 1 million tons in 2012, dwarfed by China＇s net imports of grains which reached 66.7 million tons in the same year. This slow growth in meat trade seems to contradict earlier expectations on increasing meat demand and imports, based upon projected shifts in consumption patterns driven by rapid per capita income growth. Several plausible explanations of this paradoxical trade pattern are offered, including mass imports of feed grains, persistent（but shrinking） gaps between Chinese and international meat prices, tariff barriers, and non-tariff measures. In the near future China may not be able to maintain such a lower profile on the world meat markets, as per capita income is projected to continue to rise and domestic production cost advantages erode due to rising labor costs. A model-based projection exercise indicates that under plausible assumptions China＇s meat imports may rise sharply by 2030.

VISCOMETRIC INVESTIGATIONS OF POLYVINYLPYRROLIDONE IN MIXED SOLVENTS AND WITH VARYING TEMPERATURE

The viscosity behavior of polyvinylpyrrolidone(PVP)has been determined at 25℃ in mixed solvents comprising water/dimethylformamide(DMF)and water/methanol(MeOH).Analysis of the data has considered the PVP as being both host and guest polymer in solution.The intrinsic viscosity of PVP in DMF is higher than in water and in MeOH,but also increases in a mixed solvent with high water content because of the effect of polymer-solvent interactions.It was also found that the intrinsic viscosity of PVP at finite concentration,[η_(pvp)]_c decreases with an increase in the concentration of PVP in solution.The viscosity behavior of PVP in a mixed solvent is affected by the concentration-dependent intermolecular excluded volume effect,which can be quantitatively expressed by the parameter,b_Y,which reflects the shrinkage of PVP chain coils,resulting in a decrease of[η_(pvp)]_c.The effect of temperature on the viscosity behavior of PVP in MeOH shows that the interaction parameter increases up to a maximum value,and then decreases after a certain temperature.

COMPLEXITY ANALYSIS OF TIME SERIES GENERATED BY ELEMENTARY CELLULAR AUTOMATA

Using the tools of distinct excluded blocks, computational search and symbolic dynamics, the classification problem of all 256 elementary cellular automata is discussed from the point of view of time series generated by them,and examples in each class are provided to explain the methods used.

D-MELD risk capping improves post-transplant and overall mortality under markov microsimulation

AIM: To hypothesize that the product of calculated Model for End-Stage Liver Disease score excluding exception points and donor age(D-MELD) risk capping ± Rule 14 could improve post liver transplant and overall survival after listing.METHODS: Probabilities derived from the United Network for Organ Sharing database between 2002 and 2004 were used to simulate potential outcomes for all patients listed for transplantation. The Markov simula-tion was then modified by screening matches using a 1200 or 1600 D-MELD risk cap ± allowing transplants for Model for End-Stage Liver Disease(MELD) ≤ 14(Rule 14). The differential impact of the rule changes was assessed.RESULTS: The Markov simulation accurately reproduced overall and post transplant survival. A 1200 D-MELD risk cap improved post-transplant survival. Both the 1200 and 1600 risk caps improved overall survival for waitlisted patients. The addition of Rule 14 further improved post transplant and overall survival by redistribution of donor livers to recipients in higher MELD subgroups. The mechanism for improved overall and post-transplant survival after listing was due to shifting a larger percentage of transplants to the moderate MELD score subgroup(MELD 15-29) while also ensuring that high MELD recipients have livers of high quality to achieve excellent post transplant survival.CONCLUSION: A 1200 D-MELD risk cap + Rule 14 provided the greatest overall benefit primarily by focusing liver transplantation towards the moderate MELD recipient.

Health Literacy Level of Chinese Residents Improved to 9.48%

The 2013 Monitoring Report of Health Literacy Level of Chinese Residents announced by National Health and Family Planning Commission（NHFPC）on February 17,2015 shows that health literacy level of Chinese residents had increased to 9.48%,a rise of 0.68percentage point over 8.80% in 2012 and an increase of 3 percentage points over 6.48% in 2008.

Dokk1图书馆

业主：奥胡斯市自治政府业主合作伙伴：加勒多尼亚面积：35600平方米建设费用：约280000000欧元竞赛：2009年国际竞赛第一名完工：2015年景观设计：Arkitekt Kristine Jensens Tegnestue获奖：2015年建筑评论MIPIM未来项目奖,表扬奖Client：Aarhus Municipality Client Partner：Realdania Area：35 600 m2Construction sum：Approx.Euro 280 million excluding VAT Competition：2009,fi rst prize in an international competition Status：Built 2015Landscaping：Arkitekt Kristine Jensens Tegnestue Awards：Commendation,Architectural Review MIPIM Future Projects Awards

Construction ot retroviral vectors containing human multidrug resistance gene (mdr1) and their expression in NIH3T3 cells

In order to increase the expression of mdrl genetransfectcd using retroviral vcctors, we constructedtwo retroviral vectors (LmdrlSN and MSCV-mdrl)containing mdrl cDNA and compared the expressionof mdrl gene with another vector pHamdrl/A(Pastan et al. Proc Natl Acad Sci USA 85: 4486,1986) in NIH.3T3 cells. The LmdrlSN was made

Theoretical model of biomacromolecule through nanopore including effects of electrolyte and excluded volume

A theoretical model for the translocation process of biomacromolecule is developed based on the self-consistent field theory （SCFT）, where the biomacromolecule is regarded as a self-avoiding polymer chain actuated by the external potential. In this theoretical model, the external potential, the Coulomb electrostatic potential of the charged ions （the electrolyte effect）, and the attractive interaction between the polymer and the nanopore （the excluded volume effect） are all considered, which have effects on the free energy landscape and conformation entropy during the translocation stage. The result shows that the entropy barrier of the polymer in the solution with high valence electrolyte is much larger than that with low valence electrolyte under the same condition, leading to that the translocation time of the DNA molecules in the solution increases when the valence electrolyte increases. In addition, the attractive interaction between the polymer and the nanopore increases the free energy of the polymer, which means that the probability of the translocation through the nanopore increases. The average translocation time decreases when the excluded volume effect parameter increases. The electrolyte effect can prolong the average translocation time. The simulation results agree well with the available experimental results.

Mutation of the KIT Gene, excluding Exon 11, in Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors(GISTs)are derived from the interstitial cells of Cajal,and are the most common mesenchymal tumors of the gastrointestinal tract[1].KIT proto-oncogene,receptor tyrosine kinase(KIT),and platelet-derived growth factor receptor alpha(PDGFRA)gene mutations are found in approximately 85%–90% cases of GIST.