Summary of Zhang Hongxing's Experience in Treating Refractory Angina Pectoris with Traditional Chinese Medicine

As a famous traditional Chinese medicine(TCM)expert in Shandong province and a famous veteran TCM expert in Dezhou city,Zhang Hongxing has been engaged in cardiovascular clinical work for more than 30 years.He has unique experience in the treatment of refractory angina pectoris.This paper comprehensively explains from the aspects of etiology and pathogenesis.His treatment is mostly based on syndrome differentiation,combined with the basic pharmacology of modem Chinese medicine to formulate prescriptions and drugs,and at the same time values the use of insect drugs.We hereby attach the clinical records,hoping to provide reference for clinical workers,which is conducive to the inheritance and development of famous Chinese medical academic experience.

Traditional Chinese medicine Master XIONG Jibo’s medication experience in treating arthralgia syndrome through data mining

Objective This study aimed to examine and propagate the medication experience and group formula of traditional Chinese medicine(TCM)Master XIONG Jibo in diagnosing and treat-ing arthralgia syndrome(AS)through data mining.Methods Data of outpatient cases of Professor XIONG Jibo were collected from January 1,2014 to December 31,2018,along with cases recorded in A Real Famous Traditional Chinese Medicine Doctor:XIONG Jibo's Clinical Medical Record 1,which was published in December 2019.The five variables collected from the patients’data were TCM diagnostic information,TCM and western medicine diagnoses,syndrome,treatment,and prescription.A database was established for the collected data with Excel.Using the Python environment,a custom-ized modified natural language processing(NLP)model for the diagnosis and treatment of AS by Professor XIONG Jibo was established to preprocess the data and to analyze the word cloud.Frequency analysis,association rule analysis,cluster analysis,and visual analysis of AS cases were performed based on the Traditional Chinese Medicine Inheritance Computing Platform(V3.0)and RStudio(V4.0.3).Results A total of 610 medical records of Professor XIONG Jibo were collected from the case database.A total of 103 medical records were included after data screening criteria,which comprised 187 times(45 kinds)of prescriptions and 1506 times(125 kinds)of Chinese herbs.The main related meridians were the liver,spleen,and kidney meridians.The properties of Chinese herbs used most were mainly warm,flat,and cold,while the flavors of herbs were mainly bitter,pungent,and sweet.The main patterns of AS included the damp heat,phlegm stasis,and neck arthralgia.The most commonly used herbs for AS were Chuanniuxi(Cyathu-lae Radix),Huangbo(Phellodendri Chinensis Cortex),Cangzhu(Atractylodis Rhizoma),Qinjiao(Gentianae Macrophyllae Radix),Gancao(Glycyrrhizae Radix et Rhizoma),Huangqi(Astragali Radix),and Chuanxiong(Chuanxiong Rhizoma).The most common effect of the herbs was“promoting blood circulation and removing blood stasis”,followed by“supple-menting deficiency(Qi supplementing,blood supplementing,and Yang supplementing)”,and“dispelling wind and dampness”.The data were analyzed with the support≥15%and con-fidence=100%,and after de-duplication,five second-order association rules,39 third-order association rules,39 fourth-order association rules,and two fifth-order association rules were identified.The top-ranking association rules of each were“Cangzhu(Atractylodis Rhizoma)→Huangbo(Phellodendri Chinensis Cortex)”“Cangzhu(Atractylodis Rhizoma)+Chuanniuxi(Cyathulae Radix)→Huangbo(Phellodendri Chinensis Cortex)”“Chuanniuxi(Cyathulae Radix)+Danggui(Angelicae Sinensis Radix)+Gancao(Glycyrrhizae Radix et Rhizoma)→Qinjiao(Gentianae Macrophyllae Radix)”and“Chuanniuxi(Cyathulae Radix)+Danggui(Angelicae Sinensis Radix)+Gancao(Glycyrrhizae Radix et Rhizoma)+Huangbo(Phello-dendri Chinensis Cortex)→Qinjiao(Gentianae Macrophyllae Radix)”,respectively.Five clusters were obtained using cluster analysis of the top 30 herbs.The herbs were mainly dry-ing dampness,supplementing Qi,and promoting blood circulation.The main prescriptions of AS were Ermiao San(二妙散),Gegen Jianghuang San(葛根姜黄散),and Huangqi Chongteng Yin(黄芪虫藤饮).The herbs of core prescription included Cangzhu(Atractylodis Rhizoma),Chuanniuxi(Cyathulae Radix),Gancao(Glycyrrhizae Radix et Rhizoma),Huangbo(Phellodendri Chinensis Cortex),Mugua(Chaenomelis Fructus),Qinjiao(Gentianae Macro-phyllae Radix),Danggui(Angelicae Sinensis Radix),and Yiyiren(Coicis Semen).Conclusion Clearing heat and dampness,relieving collaterals and pain,and invigorating Qi and blood are the most commonly used therapies for the treatment of AS by Professor XIONG Jibo.Additionally,customized NLP model could improve the efficiency of data mining in TCM.

Professor Liu Guobin used traditional Chinese medicine to cure a case of primary erythema limb pain

Primary erythema limb pain is a very rare disease,and its pathogenesis is not clear.Usually,the pain symptoms of patients exist for a long time,which seriously affect the daily life of patients and increase the economic burden of patients.Professor Liu Guobin,who has been engaged in the diagnosis and treatment of peripheral vascular diseases for nearly 30 years,believes that heat-toxin and blood stasis collaterals are closely related to the disease,and emphasizes the principle of heat-toxin and evil qi causing the disease.It is emphasized that clearing heat and detoxification,promoting blood circulation and dispersing blood stasis are the main treatment principles.This paper selects a typical case to describe Professor Liu's clinical experience in the treatment of primary erythema limb pain by oral and external use of traditional Chinese medicine,so as to provide an effective method of traditional Chinese medicine for the treatment of primary erythema limb pain.

Humanistic Spirit Contained in Traditional Chinese Medicine should Be Valued

Medicine is a science studying human's health and diseases as well as the regularity between them. Its research subject is human, who possess natural attribute, psychological attribute and social attribute. Therefore, medicine is bound to possess humanistic attribute. Rooted in Chinese traditional culture, Traditional Chinese Medicine contains abundant humanistic thoughts, for instance, pursuing the unity of human and nature, advocating the vital importance of life, sticking to the virtue of "medicine being humane art", abiding by the principle of "Benevolence prior to interest", complying with the medical rule of "Respecting peers". These are the very concrete reflections of medical humanistic spirit. In this article we aim to explore the humanistic thoughts contained in Traditional Chinese Medicine, and try to inherit and carry forward the spirit to better relieve the tensions between doctors and patients and improve the quality of medical services.

Experience inheritance from famous specialists based on real- world clinical research paradigm of traditional Chinese medicine

The current modes of experience inheritance from famous specialists in traditional Chinese medicine （TCM） include master and disciple, literature review, clinical-epidemiology-based clinical research observation, and analysis and data mining via computer and database technologies. Each mode has its advantages and disadvantages. However, a scientific and instructive experience inheritance mode has not been developed. The advent of the big data era as well as the formation and practice accumulation of the TCM clinical research paradigm in the real world have provided new perspectives, techniques, and methods for inheriting experience from famous TCM specialists. Through continuous exploration and practice, the research group proposes the innovation research mode based on the real-world TCM clinical research paradigm, which involves the inheritance and innovation of the existing modes. This mode is formulated in line with its own development regularity of TCM and is expected to become the main mode of experience inheritance in the clinical field.

Professor Zhang Jun's four methods for treating Children with purpuric nephritis

Based on the theory of children's TCM constitution"children are Zhi yang wei chong,and Zhi yin wei zhang",combined with the etiology and pathogenesis of TCM in children with purpuric nephritis,Professor Zhang Jun uses The four methods of"Clearing heat,dampness,tonicity,and stasis"are used to treat children with purpuric nephritis,and it is advocated that the method of"resolving blood stasis"runs through the entire treatment process,and the clinical results are quite good.

Discussion on the medication rule of Professor Ba Yuanming in the treatment of chronic glonerulonephritis based on data mining technology

Objective:To explore the medication rule of Professor Ba Yuanming in the treatment of chronic glonerulonephritis by data mining technology,so as to provide certain reference for clinical and scientific research in the treatment of Chronic glonerulonephritis with traditional Chinese medicine.Methods:collect,sort out and screen the cases of chronic nephritis diagnosed and treated by Professor Ba Yuanming in the outpatient department of Hubei Hospital of traditional Chinese medicine from 2018 to 2019,establish the database on the cloud platform of ancient and modern medical cases(v2.2.1),and use frequency statistics,association rules,hierarchical clustering and other analysis methods to study and analyze the drugs used.Results:1630 cases were included in the prescription,involving 212 traditional Chinese medicines.The high-frequency drugs are Poria cocos,astragalus,dangshen,yam,Chuanshanlong,Cornus,distracted wood,etc;the drugs are mainly warm,cold and calm;the five tastes are sweet and light,spicy and bitter;the meridian tropism is mostly found in the kidney,lung and spleen channels;the effects are calming the mind and the nerves,strengthening the spleen and stomach,promoting water and swelling,etc.The core Chinese medicine combinations of Astragalus and poria were obtained.Conclusion:Professor Ba Yuanming pays attention to comprehensive consideration,attack and supplement in the treatment of CGN,pays attention to the care of the healthy qi of Sanjiao,at the same time clearing away heat and dampness,removing blood stasis and firmness,and is good at using the sweet and gentle products.

Brief Analysis of Treatment of Postpartum Body Pain by Professor Zhang Xiaofeng from the Viewpoint of “Liver Vital Deficiency and Yang Stagnation”

Postpartum body pain is a common gynecological disease in clinical setting.Its symptoms are complex and is difficult to treat.It is often treated in many ways but with poor results,which bring great pain to patients and their families.Professor Zhang Xiaofeng can effectively improve clinical treatment of this disease from the point of view of“liver vital deficiency and yang stagnation”.This paper mainly introduces the professional experience of Professor Zhang Xiaofeng in treating postpartum body pain.A clinical case was attached for reference as proof.

张婷婷治疗子宫腺肌症痛证经验

子宫腺肌症的发病率逐年上升,其治疗是临床的难点。张婷婷教授治疗子宫腺肌症痛证,根据“瘀阻于内,不通则痛”的基本病机,口服汤剂采用“柴芍方”以疏肝行气、活血止痛;“红藤方”以清热凉血、散瘀止痛;“清瘀温通方”以寒温并用、化瘀止痛;“扶正祛瘀方”以益气扶正、祛瘀止痛。张婷婷临证还结合灌肠、足浴的方法,内外合治,长期管理患者,效果显著。

时毓民教授治疗小儿慢性咳嗽临证经验

时毓民教授认为,慢性咳嗽的病位在肺脾肾,其本质在于肺脾肾虚。文章从降中有宣以调气机、分别清解肺之余邪、活血化瘀贯穿始终、润肺止咳相佐为用、重视温阳滋肾纳气、益气滋阴固本善后六个方面总结时教授论治小儿慢性咳嗽的临证经验,并附验案一则。

医疗机构基于“三结合”中药新药研发及管理体系的构建

目的:在中药审评审批制度改革的政策背景下,围绕医疗机构,探索中医药理论、人用经验和临床试验相结合(简称“三结合”)的审评证据体系落地举措,为医疗机构中药制剂及中药新药研发提供参考。方法:根据“三结合”审评证据体系下中药新药研发的相关要求,从机构层面加强人用经验研究相关配套建设,从管理层面搭建中药研发、成果转化服务平台,从临床层面规范开展人用经验研究,构建医疗机构中药新药研发及管理体系。结果:医疗机构中药新药研发及管理体系的构建,有助于将临床诊疗数据转变为支持中药新药注册的人用经验证据,通过提高中药研发水平促进中药新药转化。结论:在医疗机构构建基于“三结合”的中药新药研发及管理体系,是“三结合”审评证据体系落地、政策引导研发实践的路径之一。

慢性肾病中医诊疗的传承与创新——西苑医院名老中医学术思想与临床经验

中国中医科学院西苑医院是我国最早开始现代中医肾病系统研究的单位之一。60多年来在多位著名老中医的引领与传承下,深入挖掘中医药治疗肾病的优势,不断吸取现代医学技术,形成了较为完善的中医优势突出的慢性肾病中西医结合防治体系。西苑医院肾病学科名医辈出,临床诊治经验丰富,学术积淀深厚,其中岳美中、方药中、时振声、聂莉芳等名老中医为现代中医肾病学的奠基者和开创者。本文聚焦名老中医对中医肾病学发展的学术贡献,从中医肾病临床诊疗的思路、肾病的辨病与中医病名、肾病证候与治法研究、临证选方用药等方面进行简要介绍。

卢传坚教授从脾肾论治慢性荨麻疹经验撷英

介绍卢传坚教授从脾肾论治慢性荨麻疹的临床经验。认为慢性荨麻疹风团之标象,从病理角度看实际属于“水湿”范畴,其发生和反复发作与“水湿运化不利”密不可分,其根本责之于“脾肾阳虚”,慢性荨麻疹的核心病机为“脾肾阳虚为其本,风湿相搏为其标”;强调以“温肾健脾治其本、祛风化湿治其标”为治疗法则,并创制“固本抗敏方”为核心方进行辨证论治,疗效显著。并附验案1则。

孙克伟教授辨证论治肝病的经验探析

孙克伟教授在长期临床诊治中总结发现,多种肝病殊途同归,提出“补脾土,疏肝解郁”“逐湿邪,热无所依”“补先天,解毒袪邪”“调气血,瘀滞得化”“温脾阳,截断逆挽”的学术经验,临床应用效果显著。该文将从以上五法探析孙克伟教授辨证论治肝病经验,旨在为肝病中医诊疗提供参考和借鉴。

谢德聪治疗妇科痛证临证经验

妇科痛证发生在少腹,以胞宫为中心,为厥阴、少阴、冲任二脉循行部位,责之“不通则痛,不荣则痛”,病因多端,虚实错杂,属于妇科疑难杂症。谢德聪认为治疗妇科痛证,注重病机,明辨虚实,临证重视调肝,养血柔肝,理气止痛,调理冲任。并遵月经生理特点与气血阴阳消长转化分期调治,经前治实,经后补虚,临床疗效显著。其诊疗思路和用药经验颇具特色,有重要的借鉴意义。

国医大师夏桂成论中医女性生殖节律理论的“节”和“律”

分述女性生命中五种节律(昼夜节律、周节律、月节律、年节律、生命节律)特征以及夏桂成教授基于生殖节律理论治疗妇科临床疾病的经验。昼夜节律是生命节律的基本单位,白天活动振奋阳气,夜间安睡静养阴血是最基本的养生准则。七为少阳数,女性的经期常持续7天,阴分充足“锦丝带”(像锦缎一样的阴道分泌物)也可达7天,更有助成孕。月经周期节律上应月下应潮,夏教授提出了经典的四期月经周期节律学说,后为了更好地描述阴阳变化,又将经典的四期分为七期,以更好地指导临床。并附验案1则。

浙派中医治疗痛经经验整理

[目的]总结1911年前浙派中医治疗痛经的经验,探究其特色。[方法]对浙派中医古籍文献中有关痛经的论述、病案等进行摘录整理,总结痛经病机及治疗特色。[结果]浙派中医治疗痛经以“气血失调”为主要病机,提倡以寒热虚实为纲的气血辨证法,从月经有无先后失期、经血色量如何、痛在经行前后三方面进行辨证。文献所记载的痛经证型共8种,分别为血气虚证、血虚有滞证、血虚有寒证、血虚有热证、冲任不足证、肝气郁滞证、气滞血瘀证、寒凝血瘀证,以“温通清化、调和血气”为治则。浙派中医发扬命门学说,擅用温药,记载痛经要药10味,分别为凌霄花、白芍、马鞭草、玄胡、京三棱、鹿角、阳起石、白头翁根、莲房、荷叶。[结论]浙派中医治疗痛经从“气血”立论,“温补”“清化”以治本,“调畅气血”为根本,以辨证论治、治病求本为宗。

吕晓东论治肺结节经验撷菁

总结吕晓东教授运用中医药治疗肺结节的临床经验和学术思想。吕晓东教授基于阳化气,阴成形的两个基本生理功能观,考察肺结节的发生、发展的病理环节,认为肺结节形成之机理复杂,病因纷繁,为阴分邪气积聚为肺,但病性基础变化总体以阳虚为关键,病理以气滞痰瘀胶着于肺络为核心。在肺络病的指导原则下,运用扶阳抑阴、通补肺络的手段,恢复阳主阴从,一气周流,肺络调和的生理状态,从而调复肺脏的异常功能状态、消弭肺结节的病理改变,恢复身心健康的目的,临床每获良效,具有推广应用的价值。

从梦与情志的关联探讨张永华情志辨证理论指导下多梦症的治疗经验

[目的]总结张永华教授运用情志辨证理论治疗多梦症的临证经验。[方法]通过整理、回顾、分析张教授治疗多梦症的医案,以梦与情志的关联为基础,从中医病理机制和治则治法等方面,总结归纳张教授应用情志辨证理论治疗多梦症的学术经验,并列举医案一则予以佐证。[结果]张教授治疗多梦症,强调梦境的情志体验重于梦境的内容本身,适宜用情志辨证方法进行辨证治疗,根据梦境的情志体验将多梦症分为思虑型、惊恐型、烦怒型、悲忧型、喜乐型五个基本证型,治疗时谨守“气、痰、火”三大核心病机,施以理气、化痰、清火等治法。所举验案为惊恐型多梦症,主要病机为“痰、火”,治以清火化痰、宁心安神,方选芩连温胆汤为底,随证加减,疗效显著。[结论]张永华教授辨治多梦症基于情志辨证理论,注重梦境中的情志体验,经验独到,临床疗效显著,值得推广应用。

陈华教授传承浙派中医儿科学术特色治疗小儿肺系疾病经验探析

[目的]总结陈华教授传承浙派中医儿科学术特色治疗小儿肺系疾病的经验。[方法]通过随师临证,研究浙派儿科学术特点,从病因病机、遣方用药等方面阐释陈师治疗小儿肺系疾病的临床经验及方药特色,并通过临床验案加以佐证。[结果]陈师诊疗小儿肺系疾病的经验可概括为融通中西,谨守病机;四望一听,尤重望诊;分期论治,善用和清;用药轻灵,顾护脾胃。所列案例为小儿急性上呼吸道感染的典型案例,急性感染期解表清里,迁延反复期益气养阴,缓解恢复期补肺健脾,疗效显著。[结论]陈师小儿肺系疾病的诊治经验,不仅有较高临床实用价值,更是对浙派中医儿科学术特色的传承和发展。