To understand how differentially methylated genes(DMGs)might affect the pathogenesis of Kashin-Beck disease(KBD).Genome-wide methylation profiling of whole blood from 12matched KBD and controls pairs was performed...To understand how differentially methylated genes(DMGs)might affect the pathogenesis of Kashin-Beck disease(KBD).Genome-wide methylation profiling of whole blood from 12matched KBD and controls pairs was performed using a high-resolution Infinium 450 K methylation array.In total,97 CpG sites were differentially展开更多
基金supported by grants from the National Natural Science Foundation of China(No.81273007)
文摘To understand how differentially methylated genes(DMGs)might affect the pathogenesis of Kashin-Beck disease(KBD).Genome-wide methylation profiling of whole blood from 12matched KBD and controls pairs was performed using a high-resolution Infinium 450 K methylation array.In total,97 CpG sites were differentially