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Masquelet technique using an allogeneic cortical bone graft for a large bone defect:A case report
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作者 Hai-Yang Zong Yu Liu +2 位作者 Xing Yin Wei Zhou Nan Li 《World Journal of Clinical Cases》 SCIE 2025年第5期36-43,共8页
BACKGROUND The induced-membrane technique was initially described by Masquelet as an effective treatment for large bone defects,especially those caused by infection.Here,we report a case of chronic osteomyelitis of th... BACKGROUND The induced-membrane technique was initially described by Masquelet as an effective treatment for large bone defects,especially those caused by infection.Here,we report a case of chronic osteomyelitis of the radius associated with a 9 cm bone defect,which was filled with a large allogeneic cortical bone graft from a bone bank.Complete bony union was achieved after 14 months of follow-up.Previous studies have used autogenous bone as the primary bone source for the Masquelet technique;in our case,the exclusive use of allografts is as successful as the use of autologous bone grafts.With the advent of bone banks,it is possible to obtain an unlimited amount of allograft,and the Masquelet technique may be further improved based on this new way of bone grafting.CASE SUMMARY In this study,we reported a case of repair of a long bone defect in a 40-year-old male patient,which was characterized by the utilization of allograft cortical bone combined with the Masquelet technique for the treatment of the patient's long bone defect in the forearm.The patient's results of functional recovery of the forearm were surprising,which further deepens the scope of application of Masquelet technique and helps to strengthen the efficacy of Masquelet technique in the treatment of long bones indeed.CONCLUSION Allograft cortical bone combined with the Masquelet technique provides a new method of treatment to large bone defect. 展开更多
关键词 OSTEOMYELITIS Bone defect Allogeneic cortical bone Masquelet technique Membrane induction technique Case report
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An Enhanced Lung Cancer Detection Approach Using Dual-Model Deep Learning Technique
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作者 Sumaia Mohamed Elhassan Saad Mohamed Darwish Saleh Mesbah Elkaffas 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期835-867,共33页
Lung cancer continues to be a leading cause of cancer-related deaths worldwide,emphasizing the critical need for improved diagnostic techniques.Early detection of lung tumors significantly increases the chances of suc... Lung cancer continues to be a leading cause of cancer-related deaths worldwide,emphasizing the critical need for improved diagnostic techniques.Early detection of lung tumors significantly increases the chances of successful treatment and survival.However,current diagnostic methods often fail to detect tumors at an early stage or to accurately pinpoint their location within the lung tissue.Single-model deep learning technologies for lung cancer detection,while beneficial,cannot capture the full range of features present in medical imaging data,leading to incomplete or inaccurate detection.Furthermore,it may not be robust enough to handle the wide variability in medical images due to different imaging conditions,patient anatomy,and tumor characteristics.To overcome these disadvantages,dual-model or multi-model approaches can be employed.This research focuses on enhancing the detection of lung cancer by utilizing a combination of two learning models:a Convolutional Neural Network(CNN)for categorization and the You Only Look Once(YOLOv8)architecture for real-time identification and pinpointing of tumors.CNNs automatically learn to extract hierarchical features from raw image data,capturing patterns such as edges,textures,and complex structures that are crucial for identifying lung cancer.YOLOv8 incorporates multiscale feature extraction,enabling the detection of tumors of varying sizes and scales within a single image.This is particularly beneficial for identifying small or irregularly shaped tumors that may be challenging to detect.Furthermore,through the utilization of cutting-edge data augmentation methods,such as Deep Convolutional Generative Adversarial Networks(DCGAN),the suggested approach can handle the issue of limited data and boost the models’ability to learn from diverse and comprehensive datasets.The combined method not only improved accuracy and localization but also ensured efficient real-time processing,which is crucial for practical clinical applications.The CNN achieved an accuracy of 97.67%in classifying lung tissues into healthy and cancerous categories.The YOLOv8 model achieved an Intersection over Union(IoU)score of 0.85 for tumor localization,reflecting high precision in detecting and marking tumor boundaries within the images.Finally,the incorporation of synthetic images generated by DCGAN led to a 10%improvement in both the CNN classification accuracy and YOLOv8 detection performance. 展开更多
关键词 Lung cancer detection dual-model deep learning technique data augmentation CNN YOLOv8
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Advancements and challenges in neuroimaging for the diagnosis of intracranial aneurysms:Addressing false positive diagnoses and emerging techniques
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作者 Nanthida Arora Sombat Muengtaweepongsa 《World Journal of Clinical Cases》 SCIE 2025年第6期48-50,共3页
Despite advancements in neuroimaging,false positive diagnoses of intracranial aneurysms remain a significant concern.This article examines the causes,prevalence,and implications of such false-positive diagnoses.We dis... Despite advancements in neuroimaging,false positive diagnoses of intracranial aneurysms remain a significant concern.This article examines the causes,prevalence,and implications of such false-positive diagnoses.We discuss how conditions like arterial occlusion with vascular stump formation and infundibular widening can mimic aneurysms,particularly in the anterior circulation.The article compares various imaging modalities,including computer tomography angiogram,magnetic resonance imaging/angiography,and digital subtraction angiogram,highlighting their strengths and limitations.We emphasize the im-portance of accurate differentiation to avoid unnecessary surgical interventions.The potential of emerging technologies,such as high-resolution vessel wall ima-ging and deep neural networks for automated detection,is explored as promising avenues for improving diagnostic accuracy.This manuscript underscores the need for continued research and clinical vigilance in the diagnosis of intracranial aneurysms. 展开更多
关键词 Intracranial aneurysms Neuroimaging techniques Computed tomographic angiography Magnetic resonance angiography Digital subtraction angiography False positive diagnoses
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Explosion temperature mapping of emulsion explosives containing TiH_(2)powders with the two-color pyrometer technique 被引量:4
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作者 Yu-Le Yao Yang-Fan Cheng +4 位作者 Qi-Wei Zhang Yu Xia Fang-Fang Hu Quan Wang Yuan Chen 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2022年第10期1834-1841,共8页
In the study,the two-color pyrometer technique was used to measure the transient temperature field of emulsion explosives with different contents of TiH_(2)powders.The experimental results showed that the introduction... In the study,the two-color pyrometer technique was used to measure the transient temperature field of emulsion explosives with different contents of TiH_(2)powders.The experimental results showed that the introduction of TiH_(2)powders could significantly increase the explosion temperature and fireball duration of emulsion explosive.When emulsion explosives were ignited,the average explosion temperature of pure emulsion explosive continuously decreased while emulsion explosives added with TiH_(2)powders increased at first and then decreased.When the content of TiH_(2)powders was 6 mass%,the explosion average temperature reached its maximum value of 3095 K,increasing by 43.7%as compared with that of pure emulsion explosive.In addition,the results of air blast experiment and explosion heat test showed that the variation trends of shock wave parameters,explosion heat and theoretical explosion temperature of emulsion explosives with different contents of TiH_(2)powders were basically consistent with that of explosion temperature measured by the two-color pyrometer technique.In conclusion,the two-color pyrometer technique would be conducive to the formula design of emulsion explosive by understanding the explosion temperature characteristics. 展开更多
关键词 Two-color pyrometer Emulsion explosive explosion temperature field explosion heat
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Numerical and Experimental Investigation into Plane Charge Explosion Technique
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作者 ZHANG Yadong LIU Ou FANG Qin XIANG Hengbo 《Transactions of Tianjin University》 EI CAS 2006年第B09期51-55,共5页
Plane charge explosion technique (PCET) is one of the major techniques frequently used in large-scale blast-resistant structure tests. An FEM model was established, which can simulate the process of air releasing from... Plane charge explosion technique (PCET) is one of the major techniques frequently used in large-scale blast-resistant structure tests. An FEM model was established, which can simulate the process of air releasing from the blast cavity. The effects of the charge density, the interval of the charge strip, the distance of the charges from the structure, and the mass of backfill soil on the overpressures applied on the tested structures were analyzed by the FEM model. The quantitative relationships between the peak value and the duration of the overpressure and the above-mentioned affecting parameters were established. Agreement between numerical results and the test data was obtained. 展开更多
关键词 plane charge explosion technique blast wave numerical simulation LS-DYNA
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A novel method for simulating nuclear explosion with chemical explosion to form an approximate plane wave: Field test and numerical simulation 被引量:1
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作者 Wei Ming Xiaojie Yang +3 位作者 Yadong Mao Xiang Wang Manchao He Zhigang Tao 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2137-2153,共17页
A nuclear explosion in the rock mass medium can produce strong shock waves,seismic shocks,and other destructive effects,which can cause extreme damage to the underground protection infrastructures.With the increase in... A nuclear explosion in the rock mass medium can produce strong shock waves,seismic shocks,and other destructive effects,which can cause extreme damage to the underground protection infrastructures.With the increase in nuclear explosion power,underground protection engineering enabled by explosion-proof impact theory and technology ushered in a new challenge.This paper proposes to simulate nuclear explosion tests with on-site chemical explosion tests in the form of multi-hole explosions.First,the mechanism of using multi-hole simultaneous blasting to simulate a nuclear explosion to generate approximate plane waves was analyzed.The plane pressure curve at the vault of the underground protective tunnel under the action of the multi-hole simultaneous blasting was then obtained using the impact test in the rock mass at the site.According to the peak pressure at the vault plane,it was divided into three regions:the stress superposition region,the superposition region after surface reflection,and the approximate plane stress wave zone.A numerical simulation approach was developed using PFC and FLAC to study the peak particle velocity in the surrounding rock of the underground protective cave under the action of multi-hole blasting.The time-history curves of pressure and peak pressure partition obtained by the on-site multi-hole simultaneous blasting test and numerical simulation were compared and analyzed,to verify the correctness and rationality of the formation of an approximate plane wave in the simulated nuclear explosion.This comparison and analysis also provided a theoretical foundation and some research ideas for the ensuing study on the impact of a nuclear explosion. 展开更多
关键词 Approximate plane wave Multi-hole simultaneous blasting Chemical explosion Nuclear explosion Pressure sensor inclusion
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Understanding the Mechanism of Nanoparticle Formation in a Wire Explosion Process by Adopting the Optical Emission Technique
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作者 B.DEBALINA M.KAMARAJ +2 位作者 S.R.CHAKRAVARTHI N.J.VASA R.SARATHI 《Plasma Science and Technology》 SCIE EI CAS CSCD 2013年第6期562-569,共8页
In the present study nano-tungsten carbide particles were generated in a wire explosion process.The plasma generated during the wire explosion process was analyzed using optical emission spectroscopy(OES).The impact... In the present study nano-tungsten carbide particles were generated in a wire explosion process.The plasma generated during the wire explosion process was analyzed using optical emission spectroscopy(OES).The impact of ambient pressure on the plasma temperature,electron density and plasma lifetime was studied.Lifetime variations of the plasma produced under different experimental conditions were analyzed.The produced nanoparticles were characterized through wide angle X-ray diffraction(WAXD) and transmission electron microscopy(TEM) studies. Particles produced with a negative DC charging voltage had a larger mean size when compared to a positive charging voltage.Polarity dependence on the plasma duration was observed where plasma was sustained for a longer duration with a negative DC charging voltage. 展开更多
关键词 optical emission wire explosion tungsten carbide life time nano particle
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Clinical diagnostic advances in intestinal anastomotic techniques:Hand suturing,stapling,and compression devices 被引量:1
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作者 Ah Young Lee Joo Young Cho 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第5期1231-1234,共4页
The development of intestinal anastomosis techniques,including hand suturing,stapling,and compression anastomoses,has been a significant advancement in surgical practice.These methods aim to prevent leakage and minimi... The development of intestinal anastomosis techniques,including hand suturing,stapling,and compression anastomoses,has been a significant advancement in surgical practice.These methods aim to prevent leakage and minimize tissue fibrosis,which can lead to stricture formation.The healing process involves various phases:hemostasis and inflammation,proliferation,and remodeling.Mechanical staplers and sutures can cause inflammation and fibrosis due to the release of profibrotic chemokines.Compression anastomosis devices,including those made of nickel-titanium alloy,offer a minimally invasive option for various surgical challenges and have shown safety and efficacy.However,despite advancements,anastomotic techniques are evaluated based on leakage risk,with complications being a primary concern.Newer devices like Magnamosis use magnetic rings for compression anastomosis,demonstrating greater strength and patency compared to stapling.Magnetic technology is also being explored for other medical treatments.While there are promising results,particularly in animal models,the realworld application in humans is limited,and further research is needed to assess their safety and practicality. 展开更多
关键词 ANASTOMOSES Diagnostic advances Anastomotic techniques technique Intestine
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Predictive modeling for postoperative delirium in elderly patients with abdominal malignancies using synthetic minority oversampling technique 被引量:3
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作者 Wen-Jing Hu Gang Bai +6 位作者 Yan Wang Dong-Mei Hong Jin-Hua Jiang Jia-Xun Li Yin Hua Xin-Yu Wang Ying Chen 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第4期1227-1235,共9页
BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling techn... BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling technique(SMOTE)-based model for predicting postoperative delirium in elderly abdominal cancer patients.METHODS In this retrospective cohort study,we analyzed data from 611 elderly patients who underwent abdominal malignant tumor surgery at our hospital between September 2020 and October 2022.The incidence of postoperative delirium was recorded for 7 d post-surgery.Patients were divided into delirium and non-delirium groups based on the occurrence of postoperative delirium or not.A multivariate logistic regression model was used to identify risk factors and develop a predictive model for postoperative delirium.The SMOTE technique was applied to enhance the model by oversampling the delirium cases.The model’s predictive accuracy was then validated.RESULTS In our study involving 611 elderly patients with abdominal malignant tumors,multivariate logistic regression analysis identified significant risk factors for postoperative delirium.These included the Charlson comorbidity index,American Society of Anesthesiologists classification,history of cerebrovascular disease,surgical duration,perioperative blood transfusion,and postoperative pain score.The incidence rate of postoperative delirium in our study was 22.91%.The original predictive model(P1)exhibited an area under the receiver operating characteristic curve of 0.862.In comparison,the SMOTE-based logistic early warning model(P2),which utilized the SMOTE oversampling algorithm,showed a slightly lower but comparable area under the curve of 0.856,suggesting no significant difference in performance between the two predictive approaches.CONCLUSION This study confirms that the SMOTE-enhanced predictive model for postoperative delirium in elderly abdominal tumor patients shows performance equivalent to that of traditional methods,effectively addressing data imbalance. 展开更多
关键词 Elderly patients Abdominal cancer Postoperative delirium Synthetic minority oversampling technique Predictive modeling Surgical outcomes
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Exploring battery material failure mechanisms through synchrotron X-ray characterization techniques 被引量:1
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作者 Lingzhe Fang Xiaozhao Liu Tao Li 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第7期128-135,共8页
Rechargeable battery cycling performance and related safety have been persistent concerns.It is crucial to decipher the capacity fading induced by electrode material failure via a range of techniques.Among these,synch... Rechargeable battery cycling performance and related safety have been persistent concerns.It is crucial to decipher the capacity fading induced by electrode material failure via a range of techniques.Among these,synchrotron-based X-ray techniques with high flux and brightness play a key role in understanding degradation mechanisms.In this comprehensive review,we summarize recent advancements in degra-dation modes and mechanisms that were revealed by synchrotron X-ray methodologies.Subsequently,an overview of X-ray absorption spectroscopy and X-ray scattering techniques is introduced for charac-terizing failure phenomena at local coordination atomic environment and long-range order crystal struc-ture scale,respectively.At last,we envision the future of exploring material failure mechanism. 展开更多
关键词 Battery failure Synchrotron-based techniques X-ray scattering X-ray absorption spectroscopy
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Hydromechanical characterization of gas transport amidst uncertainty for underground nuclear explosion detection 被引量:1
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作者 Wenfeng Li Chelsea W.Neil +3 位作者 J William Carey Meng Meng Luke P.Frash Philip H.Stauffer 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2019-2032,共14页
Given the challenge of definitively discriminating between chemical and nuclear explosions using seismic methods alone,surface detection of signature noble gas radioisotopes is considered a positive identification of ... Given the challenge of definitively discriminating between chemical and nuclear explosions using seismic methods alone,surface detection of signature noble gas radioisotopes is considered a positive identification of underground nuclear explosions(UNEs).However,the migration of signature radionuclide gases between the nuclear cavity and surface is not well understood because complex processes are involved,including the generation of complex fracture networks,reactivation of natural fractures and faults,and thermo-hydro-mechanical-chemical(THMC)coupling of radionuclide gas transport in the subsurface.In this study,we provide an experimental investigation of hydro-mechanical(HM)coupling among gas flow,stress states,rock deformation,and rock damage using a unique multi-physics triaxial direct shear rock testing system.The testing system also features redundant gas pressure and flow rate measurements,well suited for parameter uncertainty quantification.Using porous tuff and tight granite samples that are relevant to historic UNE tests,we measured the Biot effective stress coefficient,rock matrix gas permeability,and fracture gas permeability at a range of pore pressure and stress conditions.The Biot effective stress coefficient varies from 0.69 to 1 for the tuff,whose porosity averages 35.3%±0.7%,while this coefficient varies from 0.51 to 0.78 for the tight granite(porosity<1%,perhaps an underestimate).Matrix gas permeability is strongly correlated to effective stress for the granite,but not for the porous tuff.Our experiments reveal the following key engineering implications on transport of radionuclide gases post a UNE event:(1)The porous tuff shows apparent fracture dilation or compression upon stress changes,which does not necessarily change the gas permeability;(2)The granite fracture permeability shows strong stress sensitivity and is positively related to shear displacement;and(3)Hydromechanical coupling among stress states,rock damage,and gas flow appears to be stronger in tight granite than in porous tuff. 展开更多
关键词 Underground nuclear explosion uncertainty quantification Radionuclide transport Biot effective stress coefficient Fracture permeability Matrix permeability
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Improving the Segmentation of Arabic Handwriting Using Ligature Detection Technique 被引量:1
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作者 Husam Ahmad Al Hamad Mohammad Shehab 《Computers, Materials & Continua》 SCIE EI 2024年第5期2015-2034,共20页
Recognizing handwritten characters remains a critical and formidable challenge within the realm of computervision. Although considerable strides have been made in enhancing English handwritten character recognitionthr... Recognizing handwritten characters remains a critical and formidable challenge within the realm of computervision. Although considerable strides have been made in enhancing English handwritten character recognitionthrough various techniques, deciphering Arabic handwritten characters is particularly intricate. This complexityarises from the diverse array of writing styles among individuals, coupled with the various shapes that a singlecharacter can take when positioned differently within document images, rendering the task more perplexing. Inthis study, a novel segmentation method for Arabic handwritten scripts is suggested. This work aims to locatethe local minima of the vertical and diagonal word image densities to precisely identify the segmentation pointsbetween the cursive letters. The proposed method starts with pre-processing the word image without affectingits main features, then calculates the directions pixel density of the word image by scanning it vertically and fromangles 30° to 90° to count the pixel density fromall directions and address the problem of overlapping letters, whichis a commonly attitude in writing Arabic texts by many people. Local minima and thresholds are also determinedto identify the ideal segmentation area. The proposed technique is tested on samples obtained fromtwo datasets: Aself-curated image dataset and the IFN/ENIT dataset. The results demonstrate that the proposed method achievesa significant improvement in the proportions of cursive segmentation of 92.96% on our dataset, as well as 89.37%on the IFN/ENIT dataset. 展开更多
关键词 Arabic handwritten SEGMENTATION image processing ligature detection technique intelligent recognition
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Explosion resistance performance of reinforced concrete box girder coated with polyurea:Model test and numerical simulation
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作者 Guangpan Zhou Rong Wang +2 位作者 Mingyang Wang Jianguo Ding Yuye Zhang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期1-18,共18页
To study the anti-explosion protection effect of polyurea coating on reinforced concrete box girder,two segmental girder specimens were made at a scale of 1:3,numbered as G(without polyurea coating)and PCG(with polyur... To study the anti-explosion protection effect of polyurea coating on reinforced concrete box girder,two segmental girder specimens were made at a scale of 1:3,numbered as G(without polyurea coating)and PCG(with polyurea coating).The failure characteristics and dynamic responses of the specimens were compared through conducting explosion tests.The reliability of the numerical simulation using LS-DYNA software was verified by the test results.The effects of different scaled distances,reinforcement ratios,concrete strengths,coating thicknesses and ranges of polyurea were studied.The results show that the polyurea coating can effectively enhance the anti-explosion performance of the girder.The top plate of middle chamber in specimen G forms an elliptical penetrating hole,while that in specimen PCG only shows a very slight local dent.The peak vertical displacement and residual displacement of PCG decrease by 74.8% and 73.7%,respectively,compared with those of specimen G.For the TNT explosion with small equivalent,the polyurea coating has a more significant protective effect on reducing the size of fracture.With the increase of TNT equivalent,the protective effect of polyurea on reducing girder displacement becomes more significant.The optimal reinforcement ratio,concrete strength,thickness and range of polyurea coating were also drawn. 展开更多
关键词 Explosive load explosion resistance performance Model test POLYUREA Concrete box girder Numerical simulation
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Numerical Analysis of Explosion Characteristics of Vent Gas From 18650 LiFePO_(4) Batteries With Different States of Charge
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作者 Shi-Lin Wang Xu Gong +5 位作者 Li-Na Liu Yi-Tong Li Chen-Yu Zhang Le-Jun Xu Xu-Ning Feng Huai-Bin Wang 《电化学(中英文)》 CAS 北大核心 2024年第8期28-35,共8页
The combustion and explosion characteristics of lithium-ion battery vent gas is a key factor in determining the fire hazard of lithium-ion batteries.Investigating the combustion and explosion hazards of lithium-ion ba... The combustion and explosion characteristics of lithium-ion battery vent gas is a key factor in determining the fire hazard of lithium-ion batteries.Investigating the combustion and explosion hazards of lithium-ion batteries vent gas can provide guidance for rescue and protection in explosion accidents in energy storage stations and new energy vehicles,thereby promoting the application and development of lithium-ion batteries.Based on this understanding and combined with previous research on gas production from lithium-ion batteries,this article conducted a study on the combustion and explosion risks of vent gas from thermal runaway of 18650 LFP batteries with different states of charge(SOCs).The explosion limit of mixed gases affected by carbon dioxide inert gas is calculated through the“elimination”method,and the Chemkin-Pro software is used to numerically simulate the laminar flame speed and adiabatic flame temperature of the battery vent gas.And the concentration of free radicals and sensitivity coefficients of major elementary reactions in the system are analyzed to comprehensively evaluate the combustion explosion hazard of battery vent gas.The study found that the 100%SOC battery has the lowest explosion limit of the vent gas.The inhibitory elementary reaction sensitivity coefficient in the reaction system is lower and the concentration of free radicals is higher.Therefore,it has the maximum laminar flame speed and adiabatic flame temperature.The combustion and explosion hazard of battery vent gas increases with the increase of SOC,and the risk of explosion is the greatest and most harmful when SOC reaches 100%.However,the related hazards decrease to varying degrees with overcharging of the battery.This article provides a feasible method for analyzing the combustion mechanism of vent gas from lithium-ion batteries,revealing the impact of SOC on the hazardousness of battery vent gas.It provides references for the safety of storage and transportation of lithium-ion batteries,safety protection of energy storage stations,and the selection of related fire extinguishing agents. 展开更多
关键词 Combustion and explosion characteristics explosion limit Laminar flame speed Adiabatic flame temperature Sensitivity analysis
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Anti-explosion performance and dynamic response of an innovative multi-layer composite explosion containment vessel
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作者 Zhen Wang Heng Chen +3 位作者 Qi Yuan Wenbin Gu Xingbo Xie Hongwei Li 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第6期105-121,共17页
An innovative multi-layer composite explosion containment vessel(CECV)utilizing a sliding steel platealuminum honeycomb-fiber cloth sandwich is put forward to improve the anti-explosion capacity of a conventional sing... An innovative multi-layer composite explosion containment vessel(CECV)utilizing a sliding steel platealuminum honeycomb-fiber cloth sandwich is put forward to improve the anti-explosion capacity of a conventional single-layer explosion containment vessel(SECV).Firstly,a series of experiments and finite element(FE)simulations of internal explosions are implemented to understand the basic anti-explosion characteristics of a SECV and the rationality of the computational models and methods is verified by the comparison between the experimental results and simulation results.Based on this,the CECV is designed in detail and a variety of FE simulations are carried out to investigate effects of the sandwich structure,the explosive quantity and the laying mode of the fiber cloth on anti-explosion performance and dynamic response of the CECV under internal explosions.Simulation results indicate that the end cover is the critical position for both the SECV and CECV.The maximum pressure of the explosion shock wave and the maximum strain of the CECV can be extremely declined compared to those of the SECV.As a result,the explosive quantity the CECV can sustain is up to 20 times of that the SECV can sustain.Besides,as the explosive quantity increases,the internal pressure of the CECV keeps growing and the plastic deformation and failure of the sandwich structure become more and more severe,yielding plastic strain of the CECV in addition to elastic strain.The results also reveal that the laying angles of the fiber cloth's five layers have an impact on the anti-explosion performance of the CECV.For example,the CECV with fiber cloth layered in 0°/45°/90°/45°/0°mode has the optimal anti-capacity,compared to 0°/0°/0°/0°/0°and 0°/30°/60°/30°/0°modes.Overall,owing to remarkable anti-explosion capacity,this CECV can be regarded as a promising candidate for explosion resistance. 展开更多
关键词 Explosive container Honeycomb-fiber cloth ANTI-explosion Aluminum honeycomb core COMPOSITE
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Explosion damage effects of aviation kerosene storage tank under strong ignition
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作者 Shixiang Song Cheng Wang +1 位作者 Boyang Qiao Gongtian Gu 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第7期27-38,共12页
In order to study the blast damage effects of aviation kerosene storage tanks,the out-field explosion experiments of 8 m3fixed-roof tanks were carried out.The fragments,shock wave and fireball thermal radiation of the... In order to study the blast damage effects of aviation kerosene storage tanks,the out-field explosion experiments of 8 m3fixed-roof tanks were carried out.The fragments,shock wave and fireball thermal radiation of the tank in the presence of bottom oil,half oil and full oil,as well as empty tank,were investigated under internal explosion by various TNT charge contents(1.8 kg,3.5 kg and 6.2 kg).The results showed that the tank roof was the only fragment produced,and the damage forms could be divided into three types.The increase of TNT charge content and oil volume enlarged the deformation of the tank,while the hole ratio presented a trend of increase first and then decrease.The H_r,maxand V_(max)values positively increased as increasing the TNT charge content and oil volume(from empty to half oil),but decreased in full oil.The Pmaxvalues had a progressive increase with the increment of TNT charge content,but not the case with the increase in oil volumes.The development of fireball was divided into three stages:tank roof‘towed'flame,jet flow flame tumbling and rising,and jet flow flame extinguishing.The Dmaxand Hf,maxvalues both increased as increasing TNT charge content and oil volumes.The oscillation phenomenon of fireball temperature was observed in the cooling process.The average temperature of fireball surface was positively correlated with TNT charge content,and negatively correlated with oil volumes. 展开更多
关键词 Aviation kerosene Storage tank Internal explosion Shock wave FIREBALL
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Tuning microstructures of TC4 ELI to improve explosion resistance
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作者 Changle Zhang Yangwei Wang +6 位作者 Lin Wang Zixuan Ning Guoju Li Dongping Chen Zhi-Wei Yan Yuchen Song Xucai Wang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期78-99,共22页
A reasonable heat treatment process for TC4 ELI titanium alloy is crucial to tune microstructures to improve its explosion resistance.However,there is limited investigation on tuning microstructures of TC4 ELI to impr... A reasonable heat treatment process for TC4 ELI titanium alloy is crucial to tune microstructures to improve its explosion resistance.However,there is limited investigation on tuning microstructures of TC4 ELI to improve explosion resistance.Moreover,the current challenge is quantifying microstructural changes'effects on explosion resistance and incorporating microstructural changes into finite element models.This work aims to tune microstructures to improve explosion resistance and elucidate their anti-explosion mechanism,and find a suitable method to incorporate microstructural changes into finite element models.In this work,we systematically study the deformation and failure characteristics of TC4 ELI plates with varying microstructures using an air explosion test and LS-DYNA finite element modeling.The Johnson-Cook(JC)constitutive parameters are used to quantify the effects of microstructural changes on explosion resistance and incorporate microstructural changes into finite element models.Because of the heat treatment,one plate has equiaxed microstructure and the other has bimodal microstructure.The convex of the plate after the explosion has a quadratic relationship with the charge mass,and the simulation results demonstrate high reliability,with the error less than 17.5%.Therefore,it is feasible to obtain corresponding JC constitutive parameters based on the differences in microstructures and mechanical properties and characterize the effects of microstructural changes on explosion resistance.The bimodal target exhibits excellent deformation resistance.The response of bimodal microstructure to the shock wave may be more intense under explosive loading.The well-coordinated structure of the bimodal target enhances its resistance to deformation. 展开更多
关键词 MICROSTRUCTURE Finite element modelling Parameter optimization Failure characteristics explosion resistance
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Influences of oscillation on the physical stability and explosion characteristics of solid-liquid mixed fuel
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作者 Chi Zhang Ge Song +2 位作者 Hui Guo Jiafan Ren Chunhua Bai 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第10期191-198,共8页
The stratification phenomenon resulting from differences in the physical properties of solid-liquid components seriously affect the final combustion and explosion characteristics of mixed fuel under the action of osci... The stratification phenomenon resulting from differences in the physical properties of solid-liquid components seriously affect the final combustion and explosion characteristics of mixed fuel under the action of oscillation.The effects of oscillation on the physical stability of mixed fuel with two solid-liquid ratios and three liquid component distribution ratios have been investigated using a self-designed experimental system at oscillation frequencies of 60-300 r/min.The explosion characteristics of mixed fuel before and after oscillation are gained from a 20 L spherical explosion container system.When the mass ratio of liquid components is controlled at 66.9%,64.7%,62.6%the final explosion characteristics are stable,with a maximum difference of only 0.71%.The volume of liquid fuel precipitation increases with increasing oscillation frequency when the mass ratio of liquid components reaches 71.7%,69.6%,67.7%.The fuel explosion overpressure after oscillation decreases with increasing liquid precipitation volume,and the repeatability is poor,with a maximum standard deviation of 82.736,which is much higher than the ratio without stratification.Properly controlling the mass ratio of liquid components of the mixed fuel can effectively combat the impact of oscillation on the physical state and maintain the stability of the final explosion characteristics. 展开更多
关键词 Solid-liquid mixed fuel Physical stability explosion characteristics
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The Application of Analytical Techniques to Alpha-Synuclein in Parkinson’s Disease
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作者 Olatayo Adedayo Olahanmi 《American Journal of Analytical Chemistry》 CAS 2024年第9期269-285,共17页
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms such as tremors, rigidity, and bradykinesia, as well as non-motor symptoms including cognitive impairment and mood ... Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms such as tremors, rigidity, and bradykinesia, as well as non-motor symptoms including cognitive impairment and mood disorders. A hallmark of PD is the accumulation of alpha-synuclein, a presynaptic neuronal protein that aggregates to form Lewy bodies, leading to neuronal dysfunction and cell death. The study of alpha-synuclein and its pathological forms is crucial for understanding the etiology of PD and developing effective diagnostic and therapeutic strategies. Analytical techniques play a pivotal role in elucidating the structure, function, and aggregation mechanisms of alpha-synuclein. Biochemical methods such as Western blotting and enzyme-linked immunosorbent assay (ELISA) are employed to detect and quantify alpha-synuclein in biological samples, offering insights into its expression levels and post-translational modifications. Imaging techniques like immunohistochemistry and positron emission tomography (PET) allow for the visualization of alpha-synuclein aggregates in tissue samples and in vivo, respectively, facilitating the study of its spatial distribution and progression in PD Spectroscopic methods, including nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry, provide detailed structural information on alpha-synuclein and its isoforms, aiding in the identification of conformational changes associated with aggregation. Emerging techniques such as cryo-electron microscopy (Cryo-EM) and single-molecule fluorescence enable high-resolution structural analysis and real-time monitoring of alpha-synuclein aggregation dynamics, respectively. The application of these analytical techniques has significantly advanced our understanding of the pathophysiological role of alpha-synuclein in PD. They have contributed to the identification of potential biomarkers for early diagnosis and the evaluation of therapeutic interventions targeting alpha-synuclein aggregation. Despite technical limitations and challenges in clinical translation, ongoing advancements in analytical methodologies hold promise for improving the diagnosis, monitoring, and treatment of Parkinson’s disease through a deeper understanding of alpha-synuclein pathology. 展开更多
关键词 Parkinson’s Disease ALPHA-SYNUCLEIN techniqueS
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Analysis of explosion wave interactions and rock breaking effects during dual initiation
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作者 Renshu Yang Jinjing Zuo +3 位作者 Liwei Ma Yong Zhao Zhen Liu Quanmin Xie 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第8期1788-1798,共11页
In blasting engineering, the location and number of detonation points, to a certain degree, regulate the propagation direction ofthe explosion stress wave and blasting effect. Herein, we examine the explosion wave fie... In blasting engineering, the location and number of detonation points, to a certain degree, regulate the propagation direction ofthe explosion stress wave and blasting effect. Herein, we examine the explosion wave field and rock breaking effect in terms of shockwave collision, stress change of the blast hole wall in the collision zone, and crack propagation in the collision zone. The produced shockwave on the collision surface has an intensity surpassing the sum of the intensities of the two colliding explosion shock waves. At the collisionlocation, the kinetic energy is transformed into potential energy with a reduction in particle velocity at the wave front and the wavefront pressure increases. The expansion form of the superposed shock wave is dumbbell-shaped, the shock wave velocity in the collisionarea is greater than the radial shock wave velocity, and the average propagation angle of the explosion shock waves is approximately 60°.Accordingly, a fitted relationship between blast hole wall stress and explosion wave propagation angle in the superposition area is plotted.Under the experimental conditions, the superimposed explosion wave stress of the blast hole wall is approximately 1.73 times the singleexplosionwave incident stress. The results of the model test and numerical simulations reveal that large-scale radial fracture cracks weregenerated on the blast hole wall in the superimposed area, and the width of the crack increased. The width of the large-scale radial fracturecracks formed by a strong impact is approximately 5% of the blast hole length. According to the characteristics of blast hole wallcompression, the mean peak pressures of the strongly superimposed area are approximately 1.48 and 1.84 times those of the weakly superimposedand nonsuperimposed areas, respectively. 展开更多
关键词 BLASTING shock wave collision high-speed schlieren system crack fracture characteristic explosion wave
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