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Prediction of subsurface settlement induced by shield tunnelling in sandy cobble stratum 被引量:1
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作者 Fan Wang Xiuli Du Pengfei Li 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期192-212,共21页
This study focuses on the analytical prediction of subsurface settlement induced by shield tunnelling in sandy cobble stratum considering the volumetric deformation modes of the soil above the tunnel crown.A series of... This study focuses on the analytical prediction of subsurface settlement induced by shield tunnelling in sandy cobble stratum considering the volumetric deformation modes of the soil above the tunnel crown.A series of numerical analyses is performed to examine the effects of cover depth ratio(C/D),tunnel volume loss rate(h t)and volumetric block proportion(VBP)on the characteristics of subsurface settle-ment trough and soil volume loss.Considering the ground loss variation with depth,three modes are deduced from the volumetric deformation responses of the soil above the tunnel crown.Then,analytical solutions to predict subsurface settlement for each mode are presented using stochastic medium theory.The influences of C/D,h t and VBP on the key parameters(i.e.B and N)in the analytical expressions are discussed to determine the fitting formulae of B and N.Finally,the proposed analytical solutions are validated by the comparisons with the results of model test and numerical simulation.Results show that the fitting formulae provide a convenient and reliable way to evaluate the key parameters.Besides,the analytical solutions are reasonable and available in predicting the subsurface settlement induced by shield tunnelling in sandy cobble stratum. 展开更多
关键词 Shield tunnelling Sandy cobble stratum Subsurface settlement Volumetric deformation mode Stochastic medium theory
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Discontinuity development patterns and the challenges for 3D discrete fracture network modeling on complicated exposed rock surfaces 被引量:1
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作者 Wen Zhang Ming Wei +8 位作者 Ying Zhang Tengyue Li Qing Wang Chen Cao Chun Zhu Zhengwei Li Zhenbang Nie Shuonan Wang Han Yin 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2154-2171,共18页
Natural slopes usually display complicated exposed rock surfaces that are characterized by complex and substantial terrain undulation and ubiquitous undesirable phenomena such as vegetation cover and rockfalls.This st... Natural slopes usually display complicated exposed rock surfaces that are characterized by complex and substantial terrain undulation and ubiquitous undesirable phenomena such as vegetation cover and rockfalls.This study presents a systematic outcrop research of fracture pattern variations in a complicated rock slope,and the qualitative and quantitative study of the complex phenomena impact on threedimensional(3D)discrete fracture network(DFN)modeling.As the studies of the outcrop fracture pattern have been so far focused on local variations,thus,we put forward a statistical analysis of global variations.The entire outcrop is partitioned into several subzones,and the subzone-scale variability of fracture geometric properties is analyzed(including the orientation,the density,and the trace length).The results reveal significant variations in fracture characteristics(such as the concentrative degree,the average orientation,the density,and the trace length)among different subzones.Moreover,the density of fracture sets,which is approximately parallel to the slope surface,exhibits a notably higher value compared to other fracture sets across all subzones.To improve the accuracy of the DFN modeling,the effects of three common phenomena resulting from vegetation and rockfalls are qualitatively analyzed and the corresponding quantitative data processing solutions are proposed.Subsequently,the 3D fracture geometric parameters are determined for different areas of the high-steep rock slope in terms of the subzone dimensions.The results show significant variations in the same set of 3D fracture parameters across different regions with density differing by up to tenfold and mean trace length exhibiting differences of 3e4 times.The study results present precise geological structural information,improve modeling accuracy,and provide practical solutions for addressing complex outcrop issues. 展开更多
关键词 Complicated exposed rock surfaces Discontinuity characteristic variation Three-dimensional discrete fracture network modeling Outcrop study Vegetation cover and rockfalls
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Physical and numerical investigations of target stratum selection for ground hydraulic fracturing of multiple hard roofs
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作者 Binwei Xia Yanmin Zhou +2 位作者 Xingguo Zhang Lei Zhou Zikun Ma 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第5期699-712,共14页
Ground hydraulic fracturing plays a crucial role in controlling the far-field hard roof,making it imperative to identify the most suitable target stratum for effective control.Physical experiments are conducted based ... Ground hydraulic fracturing plays a crucial role in controlling the far-field hard roof,making it imperative to identify the most suitable target stratum for effective control.Physical experiments are conducted based on engineering properties to simulate the gradual collapse of the roof during longwall top coal caving(LTCC).A numerical model is established using the material point method(MPM)and the strain-softening damage constitutive model according to the structure of the physical model.Numerical simulations are conducted to analyze the LTCC process under different hard roofs for ground hydraulic fracturing.The results show that ground hydraulic fracturing releases the energy and stress of the target stratum,resulting in a substantial lag in the fracturing of the overburden before collapse occurs in the hydraulic fracturing stratum.Ground hydraulic fracturing of a low hard roof reduces the lag effect of hydraulic fractures,dissipates the energy consumed by the fracture of the hard roof,and reduces the abutment stress.Therefore,it is advisable to prioritize the selection of the lower hard roof as the target stratum. 展开更多
关键词 Target stratum selection Ground hydraulic fracturing Hard roof control Fracture network Material point method
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Research on the design method for uniform wear of shield cutters in sand-pebble strata
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作者 Jinxun Zhang Bo Li +4 位作者 Guihe Wang Yusheng Jiang Hua Jiang Minglun Yin Zhengyang Sun 《Deep Underground Science and Engineering》 2024年第2期216-230,共15页
During shield tunneling in highly abrasive formations such as sand–pebble strata,nonuniform wear of shield cutters is inevitable due to the different cutting distances.Frequent downtimes and cutter replacements have ... During shield tunneling in highly abrasive formations such as sand–pebble strata,nonuniform wear of shield cutters is inevitable due to the different cutting distances.Frequent downtimes and cutter replacements have become major obstacles to long-distance shield driving in sand–pebble strata.Based on the cutter wear characteristics in sand–pebble strata in Beijing,a design methodology for the cutterhead and cutters was established in this study to achieve uniform wear of all cutters by the principle of frictional wear.The applicability of the design method was verified through three-dimensional simulations using the engineering discrete element method.The results show that uniform wear of all cutters on the cutterhead could be achieved by installing different numbers of cutters on each trajectory radius and designing a curved spoke with a certain arch height according to the shield diameter.Under the uniform wear scheme,the cutter wear coefficient is greatly reduced,and the largest shield driving distance is increased by approximately 47%over the engineering scheme.The research results indicate that the problem of nonuniform cutter wear in shield excavation could be overcome,thereby providing guiding significance for theoretical innovation and construction of long-distance shield excavation in highly abrasive strata. 展开更多
关键词 cutter wear EDEM model long-distance shield driving sand-pebble stratum shield tunnel uniform wear design method
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Correction to:Wear mechanism and life prediction of the ripper in a 9‐m‐diameter shield machine tunneling project of the Beijing new airport line in a sand‐pebble stratum
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《Deep Underground Science and Engineering》 2023年第3期274-274,共1页
Jiang H,Zhu J,Zhang X,Zhang J,Li H,Meng L.Wear mechanism and life prediction of the ripper in a 9‐m‐diameter shield machine tunneling project of the Beijing new airport line in a sand‐pebble stratum.Deep Undergr Sc... Jiang H,Zhu J,Zhang X,Zhang J,Li H,Meng L.Wear mechanism and life prediction of the ripper in a 9‐m‐diameter shield machine tunneling project of the Beijing new airport line in a sand‐pebble stratum.Deep Undergr Sci Eng.2022;1:65‐76.doi:10.1002/dug2.12010. 展开更多
关键词 TUNNELING mechanism stratum
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Study on the disaster caused by the linkage failure of the residual coal pillar and rock stratum during multiple coal seam mining:mechanism of progressive and dynamic failure
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作者 Yunliang Tan Qing Ma +4 位作者 Xiaoli Liu Xuesheng Liu Derek Elsworth Ruipengg Qian Junlong Shang 《International Journal of Coal Science & Technology》 EI CAS CSCD 2023年第3期122-135,共14页
Multi-seam mining often leads to the retention of a significant number of coal pillars for purposes such as protection,safety,or water isolation.However,stress concentration beneath these residual coal pillars can sig... Multi-seam mining often leads to the retention of a significant number of coal pillars for purposes such as protection,safety,or water isolation.However,stress concentration beneath these residual coal pillars can significantly impact their strength and stability when mining below them,potentially leading to hydraulic support failure,surface subsidence,and rock bursting.To address this issue,the linkage between the failure and instability of residual coal pillars and rock strata during multi-seam mining is examined in this study.Key controls include residual pillar spalling,safety factor(f.),local mine stiffness(LMS),and the post-peak stiffness(k)of the residual coal pillar.Limits separating the two forms of failure,progressive versus dynamic,are defined.Progressive failure results at lower stresses when the coal pillar transitions from indefinitely stable(f,>1.5)to failing(f,<1.5)when the coal pillar can no longer remain stable for an extended duration,whereas sud-den(unstable)failure results when the strength of the pillar is further degraded and fails.The transition in mode of failure is defined by the LMS/k ratio.Failure transitions from quiescent to dynamic as LMS/k.<1,which can cause chain pillar instability propagating throughout the mine.This study provides theoretical guidance to define this limit to instability of residual coal pillars for multi-seam mining in similar mines. 展开更多
关键词 Multi-seam mining Residual coal pillars Rock stratum Linkage instability mechanism Local mine stiffness
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Exploring the mechanism of moist exposed burn ointment for the treatment of diabetic ulcer based on network pharmacology and molecular docking
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作者 YANG Ya-liang GE Xing-yue +3 位作者 LI Wen-wu ZHU Shi-lin YAO Ming-zhe TANG Qian-li 《Journal of Hainan Medical University》 CAS 2023年第22期39-47,共9页
Objective:To discuss the main active components and potential mechanisms of moist burn ointment in the treat-ment of diabetic ulcer were discussed by network pharmacology and molecular docking technology.Methods:Based... Objective:To discuss the main active components and potential mechanisms of moist burn ointment in the treat-ment of diabetic ulcer were discussed by network pharmacology and molecular docking technology.Methods:Based on the TC-MSP database,the main active components and targets of MEBO were screened.The targets related to diabetic ulcers were searched from GeneCards,OMIM,PharmGkb,TTD,and DrugBank databases.The STRING 11.5 database was used to con-struct a protein-protein interaction(PPI)network to screen the core targets.The'drug-target-disease'network diagram was made in Cytoscape 3.8.2 software to screen the core active components.GO enrichment analysis and KEGG pathway enrichment analysis were performed using R language software.Finally,molecular docking was used to preliminarily verify the screening results.Results:A total of 37 active components of MEBO were screened to map 100 targets,5527 targets for diabetic ulcer dis-ease,and 77 intersection targets.PPI network topology analysis suggested that TP53,TNF,HSP90AA1 and other targets were key targets;the network diagram of ‘drug-target-disease’showed that acacetin,wogonin,quercetin,and rutaecarpine were the core active ingredients.GO function analysis mainly involved angiogenesis,ion transport,diameter regulation,cytokine receptor binding,and other processes.KEGG enrichment analysis mainly included PI3K-Akt,AGE-RAGE,and other signaling pathways.Molecular docking showed that the core active ingredients and key targets had good docking activity.Conclusion:The treatment of diabetic ulcer with MEBO is the result of multi-component,multi-target,and synergistic regulation,which provides a theoretical basis for the clinical application of MEBO and the treatment of diabetic ulcer. 展开更多
关键词 Network pharmacology Molecular docking Moist exposed burn ointment Diabetic ulcers
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Deoxyribonucleic Acid-Polymerase Chain Reaction Status of HIV Exposed Infants in a Sub Regional Prevention of Mother-to-Child Transmission of HIV Programme during the Period 2009-2020
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作者 Elon Warnow Isaac Ayomikun Ajani +4 位作者 Jalo Iliya Mohammed Manga Abubakar Joshua Difa Oyeniyi Christianah Oluwaseun Muhammad Danlami Hassan 《Open Journal of Epidemiology》 2023年第4期328-341,共14页
Introduction: Transitioning to more efficacious Antiretrovirals for HIV infected pregnant women and infant prophylaxis has reduced Mother to child transmission of HIV significantly. This study aimed to determine HIV i... Introduction: Transitioning to more efficacious Antiretrovirals for HIV infected pregnant women and infant prophylaxis has reduced Mother to child transmission of HIV significantly. This study aimed to determine HIV infection status in HIVexposed infants who had their first DNA polymerase chain reaction test in our molecular Laboratory. Subjects, Materials and Methods: Dried Blood Spots for HIV DNA results from 5 states between 2009 and 2020 were analyzed in the PCR laboratory of the Federal Teaching Hospital, Gombe. Results: Nine thousand eight hundred and twenty-three Human Immunodeficiency Virus Deoxyribonucleic acid polymerase Chain Reaction results were analysed;4937 (50.2%) were males. During the study period, there was an overall declining trend in the mother-to-child transmission rate from 3.8% in 2009 to 1.0% in 2020. 6120 (62.3%) of HIV + mothers received Highly active antiretroviral therapy HAART before pregnancy. 7845 (76.2%) of the infants received Nevirapine prophylaxis. Dried blood spot samples were collected from 4077 (41.5%) at 6 - 8 weeks. 8438 (85.9%) received cotrimoxazole. 9469 (96.4%) were ever breastfed. Of the 9823 HIV DNA PCR results, 255 (2.6%) were positive while 69/4077 (1.7%) and 109/2662 (4.1%) were positive for HIV DNA at 6 - 8 weeks and > 12 weeks respectively. (p = 0.001). 86/747 (11.5%) of infants whose HIV-positive mothers received no ARVS were HIV DNA positive. (p = 0.001). 106/884 (12.0%) of infants who had no Antiretroviral prophylaxis had positive HIV DNA results;7/413 (1.7%) with Zidovudine/Nevirapine prophylaxis had positive results. (p = 0.001). 246/9469 (2.6%) of infants that were ever breastfed were positive for HIV DNA;11/354 (3.0%) that never breastfed had positive HIV DNA. Conclusion: Lack of maternal/infant ARVs and prolonged breastfeeding increased the risk of infant HIV infection. 展开更多
关键词 Mother to Child Transmission of HIV aNTIRETROVIRaLS HIV exposed Infants Deoxyribonucleic acid Polymerase Chain Reaction Early Infant Diagnosis
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F-doped orthorhombic Nb_(2)O_(5) exposed with 97% (100) facet for fast reversible Liþ-Intercalation
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作者 Xiaodi Liu Yufeng Tang +5 位作者 Dan Zhang Guangyin Liu Xinwei Luo Yi Shang Xiu Li Jianmin Ma 《Green Energy & Environment》 SCIE EI CAS CSCD 2024年第4期723-731,共9页
Orthorhombic Nb_(2)O_(5)(T-Nb_(2)O_(5))is attractive for fast-charging Li-ion batteries,but it is still hard to realize rapid charge transfer kinetics for Li-ion storage.Herein,F-doped T-Nb_(2)O_(5) microflowers(F-Nb_(... Orthorhombic Nb_(2)O_(5)(T-Nb_(2)O_(5))is attractive for fast-charging Li-ion batteries,but it is still hard to realize rapid charge transfer kinetics for Li-ion storage.Herein,F-doped T-Nb_(2)O_(5) microflowers(F-Nb_(2)O_(5))are rationally synthesized through topotactic conversion.Specifically,F-Nb_(2)O_(5) are assembled by single-crystal nanoflakes with nearly 97%exposed(100)facet,which maximizes the exposure of the feasible Li^(+)transport pathways along loosely packed 4g atomic layers to the electrolytes,thus effectively enhancing the Li^(+)-intercalation performance.Besides,the band gap of F-Nb_(2)O_(5) is reduced to 2.87 eV due to the doping of F atoms,leading to enhanced electrical conductivity.The synergetic effects between tailored exposed crystal facets,F-doping,and ultrathin building blocks,speed up the Li^(+)/electron transfer kinetics and improve the pseudocapacitive properties of F-Nb_(2)O_(5).Therefore,F-Nb_(2)O_(5) exhibit superior rate capability(210.8 and 164.9 mAh g^(-1) at 1 and 10 C,respectively)and good long-term 10 C cycling performance(132.7 mAh g^(-1) after 1500 cycles). 展开更多
关键词 exposed facets Orthorhombic Nb_(2)O_(5) F-doping Pseudocapacitive intercalation anode Li-ion storage
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A method for predicting the water-flowing fractured zone height based on an improved key stratum theory 被引量:1
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作者 Jianghui He Wenping Li +3 位作者 Kaifang Fan Wei Qiao Qiqing Wang Liangning Li 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2023年第1期61-71,共11页
In the process of using the original key stratum theory to predict the height of a water-flowing fractured zone(WFZ),the influence of rock strata outside the calculation range on the rock strata within the calculation... In the process of using the original key stratum theory to predict the height of a water-flowing fractured zone(WFZ),the influence of rock strata outside the calculation range on the rock strata within the calculation range as well as the fact that the shape of the overburden deformation area will change with the excavation length are ignored.In this paper,an improved key stratum theory(IKS theory)was proposed by fixing these two shortcomings.Then,a WFZ height prediction method based on IKS theory was established and applied.First,the range of overburden involved in the analysis was determined according to the tensile stress distribution range above the goaf.Second,the key stratum in the overburden involved in the analysis was identified through IKS theory.Finally,the tendency of the WFZ to develop upward was determined by judging whether or not the identified key stratum will break.The proposed method was applied and verified in a mining case study,and the reasons for the differences in the development patterns between the WFZs in coalfields in Northwest and East China were also fully explained by this method. 展开更多
关键词 Coal mining Water-flowing fractured zone height Prediction method Improved key stratum theory
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Postoperative encapsulated hemoperitoneum in a patient with gastric stromal tumor treated by exposed endoscopic full-thickness resection: A case report
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作者 Hui-Fei Lu Jing-Jing Li +4 位作者 De-Bin Zhu Li-Qi Mao Li-Fen Xu Jing Yu Lin-Hua Yao 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第2期601-608,共8页
BACKGROUND Gastric stromal tumors,originating from mesenchymal tissues,are one of the most common tumors of the digestive tract.For stromal tumors originating from the muscularis propria,compared with conventional end... BACKGROUND Gastric stromal tumors,originating from mesenchymal tissues,are one of the most common tumors of the digestive tract.For stromal tumors originating from the muscularis propria,compared with conventional endoscopic submucosal dissection(ESD),endoscopic full-thickness resection(EFTR)can remove deep lesions and digestive tract wall tumors completely.However,this technique has major limitations such as perforation,postoperative bleeding,and post-polypectomy syndrome.Herein,we report a case of postoperative serous surface bleeding which formed an encapsulated hemoperitoneum in a patient with gastric stromal tumor that was treated with exposed EFTR.Feasible treatment options to address this complication are described.CASE SUMMARY A 47-year-old male patient had a hemispherical protrusion found during gastric endoscopic ultrasonography,located at the upper gastric curvature adjacent to the stomach fundus,with a smooth surface mucosa and poor mobility.The lesion was 19.3 mm×16.1 mm in size and originated from the fourth ultrasound layer.Computed tomography(CT)revealed no significant evidence of lymph node enlargement or distant metastasis.Using conventional ESD technology for mucosal pre-resection,exposed EFTR was performed to resect the intact tumor in order to achieve a definitive histopathological diagnosis.Based on its morphology and immunohistochemical expression of CD117 and DOG-1,the lesion was proven to be consistent with a gastric stromal tumor.Six days after exposed EFTR,CT showed a large amount of encapsulated fluid and gas accumulation around the stomach.In addition,gastroscopy suggested intracavitary bleeding and abdominal puncture drainage indicated serosal bleeding.Based on these findings,the patient was diagnosed with serosal bleeding resulting in encapsulated abdominal hemorrhage after exposed EFTR for a gastric stromal tumor.The patient received combined treatments,such as hemostasis under gastroscopy,gastrointestinal decompression,and abdominal drainage.All examinations were normal within six months of follow-up.CONCLUSION This patient developed serous surface bleeding in the gastric cavity following exposed EFTR.Serosal bleeding resulting in an encapsulated hemoperitoneum is rare in clinical practice.The combined treatment may replace certain surgical techniques. 展开更多
关键词 exposed endoscopic full-thickness resection Gastric stromal tumors HEMOPERITONEUM abdominal infection COMPLICaTION Postoperative bleeding Case report
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Study on the interaction between volatile oil components and skin lipids based on molecular docking techniques
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作者 REN Weishuo WULAN Tuya +4 位作者 DAI Xingxing ZHANG Yingying JIA Mingyue FENG Minfang SHI Xinyuan 《Digital Chinese Medicine》 CAS CSCD 2024年第2期148-159,共12页
Objective To analyze the interactions between different structural types of volatile oil compo-nents(VOCs)and skin lipid molecules;and investigate the mechanism of volatile oil in Chi-nese materia medica(VOCMM)as pene... Objective To analyze the interactions between different structural types of volatile oil compo-nents(VOCs)and skin lipid molecules;and investigate the mechanism of volatile oil in Chi-nese materia medica(VOCMM)as penetration enhancers.Methods In this study;210 different structural types of VOCs were selected from the VOCMM penetration enhancer database;and the molecular docking experiments were conducted with three main lipid molecules of skin:ceramide 2(CER2);cholesterol(CHL);and free fatty acid(FFA).Each VOC was docked individually with each lipid molecule.Cluster analysis was used to explore the relationship between the binding energy of VOCs and their molecular struc-tures.Nine specific pathogen-free(SPF)Sprague Dawley(SD)rats were randomly divided in-to Control;Nootkatone;and 3-Butylidenephthalide groups for in vitro percutaneous experi-ments;with three rats in each group.The donor pool solutions were 3%gastrodin;3%gas-trodin+3%nootkatone;and 3%gastrodin+3%3-butylidenephthalide;respectively.The pen-etration enhancing effects of VOCs with higher binding energy were evaluated by comparing the 12-hour cumulative percutaneous absorption of gastrodin(Q12;µg/cm²).Results(i)Most of the VOCs were non-hydrogen bonded to the hydrophobic parts of CHL and FFA;and hydrogen bonded to the head group of CER2.Among them;sesquiterpene ox-ides showed the most pronounced binding affinity to CER2.The VOCs with 2-4 rings(in-cluding carbon rings;benzene rings;and heterocycles)demonstrated stronger binding affini-ty for three skin lipid molecules compared with the VOCs without intramolecular rings(P<0.01).(ii)According to the cluster analysis;most of the VOCs that bond well to CER2 had 2-3 intramolecular rings.The non-oxygenated VOCs were bonded to CER2 in a hydrophobic manner.The oxygenated VOCs were mostly bonded to CER2 by hydrogen bonding.(iii)The results of Franz diffusion cell experiment showed that the Q12 of Control group was 260.60±25.09µg/cm2;and the transdermal absorption of gastrodin was significantly increased in Nootkatone group(Q12=5503.00±1080.00µg/cm²;P<0.01).The transdermal absorption of gastrodin was also increased in 3-Butylidenephthalide group(Q12=495.40±56.98µg/cm²;P>0.05).(iv)The type of oxygen-containing functional groups in VOCs was also an influencing factor of binding affinity to CER2.Conclusion The interactions between different types of VOCs with different structures in the VOCMM and three skin lipid molecules in the stratum corneum were investigated at the molecular level in this paper.This research provided theoretical guidance and data support for the screening of volatile oil-based penetration enhancers;and a simple and rapid method for studying the penetration-enhancing mechanism of volatile oils. 展开更多
关键词 Chinese materia medica Volatile oil stratum corneum lipids Transdermal penetration-enhancing effects Molecular docking Ceramide 2(CER2) Penetration enhancers
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An analytical solution for evaluating the safety of an exposed face in a paste backfill stope incorporating the arching phenomenon 被引量:11
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作者 Xu Zhao Andy Fourie Chong-chong Qi 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2019年第10期1206-1216,共11页
In current underground mining, the stability of the exposed backfill face is a basic issue associated with mining design and has been the subject of considerable research in mining safety and efficiency. In this study... In current underground mining, the stability of the exposed backfill face is a basic issue associated with mining design and has been the subject of considerable research in mining safety and efficiency. In this study, an improved analytical solution for evaluating the safety of vertically exposed faces in backfilling was proposed. Based on a differential slice method, the proposed solution emphasizes the arching effect as having the advantages of more rigor and wider scalability. Feasibility of the proposed solution was validated with classic centrifuge results. Good agreement between compared results indicated that the proposed solution skillfully predicts the behavior of the paste centrifuge model. Additionally, calculation of exposed face safety in sequential filling was presented. The proposed solution has practical significance in mine backfill design. 展开更多
关键词 mine SaFETY cemented PaSTE BaCKFILL exposed FaCE aRCHING sequential filling
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Treating aplasia cutis congenita in a newborn with the combination of ionic silver dressing and moist exposed burn ointment: A case report 被引量:4
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作者 Guo-Feng Lei Jun-Ping Zhang +6 位作者 Xiao-Bing Wang Xiao-Li You Jin-Ya Gao Xiao-Mei Li Mei-Ling Chen Xiu-Qin Ning Jiang-Li Sun 《World Journal of Clinical Cases》 SCIE 2019年第17期2611-2616,共6页
BACKGROUND Aplasia cutis congenita (ACC) in newborns is a condition in which congenital defects or hypoplasia is present in part of the epidermis,dermis and even subcutaneous tissue (including muscle and bones).First ... BACKGROUND Aplasia cutis congenita (ACC) in newborns is a condition in which congenital defects or hypoplasia is present in part of the epidermis,dermis and even subcutaneous tissue (including muscle and bones).First reported by Cordon in 1767,ACC is a rare disease with a low incidence of 1/100000 to 3/10000.Currently,there are 500 cases reported worldwide.ACC can be accompanied by other malformations.The onset mechanism of the disease remains unknown but is thought to be correlated to factors such as genetics,narrow uterus,foetal skin and amniotic membrane adhesion,use of teratogenic drugs in early pregnancy and viral infection.CASE SUMMARY In August 2018,we treated a newborn with ACC on the left lower limbs using a combination of ionic silver dressing and moist exposed burn ointment (MEBO) and achieved a satisfactory treatment outcome.The skin defects were observed on the external genitals and on areas from the left foot to 3/4 of the upper left side.Subcutaneous tissue and blood vessels were observed in the regions with skin defects.The following treatments were provided.First,the wound was rinsed with 0.9% sodium chloride solution followed by disinfection with povidone-iodine twice.And then MEBO was applied to the wound at a thickness of approximately 1 mm.After applying ionic silver dressing,the wound was covered with sterile gauze.The wound dressing was replaced every 2-3 d.At the 4-mo follow-up,the treatment outcome was satisfactory.There was minimal scar tissue formation,and limb function was not impaired.CONCLUSION The combination of ionic silver dressing and MEBO to ACC is helpful. 展开更多
关键词 aPLaSIa cutis congenita Newborns IONIC SILVER DRESSING Moist exposed burn OINTMENT
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Effect on Stratum Gradient Frequency Distribution of Landslides in the Three Gorges Area of Northeast Chongqing 被引量:1
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作者 FAN Xiaoyi QIAO Jianping 《Wuhan University Journal of Natural Sciences》 EI CAS 2006年第4期767-772,共6页
The landslide data were calculated in the Three Gorges Area of northeast Chongqing. The results showed that landslide frequency distributions of gradients accorded with the Weibull probability density distribution fun... The landslide data were calculated in the Three Gorges Area of northeast Chongqing. The results showed that landslide frequency distributions of gradients accorded with the Weibull probability density distribution function. The landslide hazard ratios of gradients were acquired by Weibull accumulation probability distribution function in the different geological units. There was discord between landslide hazard ratio of different geological units and variance of landslide gradient. But they were approximate homology in the strata of Jurassic. The results indicate that the Weibull distribution can quantitatively evaluate the landslide hazard ratios of gradients of the different strata in the Three Gorges Area. 展开更多
关键词 GRaDIENT stratum Weibull distribution LaNDSLIDE
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CORROSION BEHAVIORS OF THE EXPOSED SIDE AND UNDERSIDE OF LOW ALLOY WEATHERING STEEL IN QINGDAO AND WANNING FOR 18 MONTHS 被引量:1
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作者 S. T. Wang S. W. Yang K. W. Gao X.L. He 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2008年第6期425-436,共12页
For 18 months, a newly developed low alloy weathering steel has been exposed in two coastal sites (Qingdao in the north China, Wanning in the south China). The different corrosion behaviors of the exposed side and t... For 18 months, a newly developed low alloy weathering steel has been exposed in two coastal sites (Qingdao in the north China, Wanning in the south China). The different corrosion behaviors of the exposed side and the underside of the samples were characterized by X-ray diffraetion (XRD), polarization curve, electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), and N2 adsorption approach. It was found that the samples exhibited higher corrosion rate in Wanning than that in Qingdao. The underside of the samples corrodes more seriously than the exposed side in Qingdao, whereas the result in Wanning is just the reverse. The protection performance of rust layers mainly depends on its compactness and the enrichment of Cu and Cr is a secondary causation. The different compactness of rust layers in the exposed side and the underside originates from different corrosion conditions of the two sides. 展开更多
关键词 Low alloy weathering steel Temperate marine environment Subtropical marine environment exposed side Underside side
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Characteristics of Corrosion Product Layer Formed on Weathering Steel Exposed to the Tropical Climate of Vietnam 被引量:3
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作者 Le Thi Hong Lien Hoang Lam Hong 《Materials Sciences and Applications》 2013年第7期6-16,共11页
The weathering steel (Corten B) was exposed to out-door atmosphere of Hanoi (urban site) and Donghoi (marine site). The results showed the protective ability of corrosion product layer formed on weathering steel in th... The weathering steel (Corten B) was exposed to out-door atmosphere of Hanoi (urban site) and Donghoi (marine site). The results showed the protective ability of corrosion product layer formed on weathering steel in the initial stage. The SEM-EDX analysis detected the presence of chromium and copper in the inner layers of corrosion product formed on weathering steel. These elements improved corrosion resistance of corrosion product layers. In addition, the dense α-FeOOH phase were appeared early in corrosion product which is detected by X-ray diffraction and Micro Raman investigations. The results of polarization and EIS measurements also demonstrated the protectiveness of the corrosion product of weathering steel. 展开更多
关键词 WEatheRING Steel Corrosion Product LaYER Protectiveness exposed to INNER LaYER Outer LaYER
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Microglia activation in the offspring of prenatal Poly I:C exposed rats:a PET imaging and immunohistochemistry study 被引量:1
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作者 Xue Li Xin Tian +7 位作者 Luxian Lv Gangrui Hei Xufeng Huang Xiaoduo Fan Jinming Zhang Jianjiang Zhang Lijuan Pang Xueqin Song 《General Psychiatry》 CSCD 2018年第4期31-38,共8页
Background The well-known ‘pyrotherapy’ of Julius Wagner-Jauregg might be the beginning of the study on the immunological concepts of schizophrenia. As the primary immune effector cells in the brain, microglia play... Background The well-known ‘pyrotherapy’ of Julius Wagner-Jauregg might be the beginning of the study on the immunological concepts of schizophrenia. As the primary immune effector cells in the brain, microglia play a pivotal role in neuroinfammatory processes. Maternal viral infection during pregnancy is associated with an increased risk for psychiatric disorders with presumed neurodevelopmental origin, including autism spectrum disorders and schizophrenia. The present study was to quantify microglia activation in vivo in the mature offspring of rats exposed to polyriboinosinic–polyribocytidilicacid (Poly I:C) during pregnancy using ^11C-PK11195 positron emission tomography (PET) and immunohistochemistry.Objective The study aimed to quantify microglia activation in vivo in the prefrontal cortex and hippocampus in mature offspring of prenatal Poly I:C exposed rats.Methods Offspring of Poly I:C-treated dams were the model group, offspring of saline-treated dams were the control group. Behavioural test for two groups was taken by spontaneous activity, prepulse inhibition (PPI) and latent inhibition (LI) test (including active avoidance conditioning task and passive avoidance conditioning task). Randomly selected successful model rats were assessed by behavioural test in the model group and control group rats. 11C-PK11195 micro-PET/CT and immunohistochemistry were performed on the selected rats to measure microglia activation.Results The treatment group showed hyperlocomotion and defcits in PPI and LI compared with the control group. The treatment group also showed an increased 11C-PK11195 uptake ratio in the prefrontal cortex (t=-3.990, p=0.003) and hippocampus (t=-4.462, p=0.001). The number of activated microglia cells was signifcantly higher in the treatment group than in the control group (hippocampus: t=8.204, p〈0.001; prefrontal: t=6.995, p〈0.001). Within the treatment group, there were signifcant correlations between the behavioural parameters and the activation of microglia as measured by PET and immunohistochemistry.Conclusions The present study demonstrated microglia activation in vivo in the prefrontal cortex and hippocampus in mature offspring of prenatal Poly I:C exposed rats. This study suggests that microglia activation may play a possible or potential role in the pathogenesis of schizophrenia. 展开更多
关键词 Microglia activation the offspring of prenatal Poly I C exposed rats a PET imaging and immunohistochemistry study
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Synthesis and Optimization of TiO_(2)/Graphene with Exposed {001} Facets Based on Response Surface Methodology and Evaluation of Enhanced Photocatalytic Activity 被引量:2
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作者 Yifei Wang Zhiyang Zhang +2 位作者 Qianqian Shang Xin Tan Hongmei Wang 《Transactions of Tianjin University》 EI CAS 2018年第5期415-423,共9页
Response surface methodology(RSM)was employed to optimize the control parameters of TiO_(2)/graphene with exposed{001}facets during synthesis,and its enhanced photocatalytic activities were evaluated in the photodegra... Response surface methodology(RSM)was employed to optimize the control parameters of TiO_(2)/graphene with exposed{001}facets during synthesis,and its enhanced photocatalytic activities were evaluated in the photodegradation of toluene.Experimental results were in good agreement with the predicted results obtained using RSM with a correlation coefficient(R^(2))of 0.9345.When 22.06 mg of graphite oxide(GO)and 2.09 mL of hydrofluoric acid(HF)were added and a hydrothermal time of 28 h was used,a maximum efficiency in the degradation of toluene was achieved.X-ray diffraction(XRD),transmission electron microscopy(TEM),and scanning electron microscopy(SEM)were employed to characterize the obtained hybrid photocatalyst.The electron transferred between Ti and C retarded the combination of electron–hole pairs and hastened the transferring of electrons,which enhanced the photocatalytic activity. 展开更多
关键词 TiO2/graphene exposed{001}facets SYNtheSIS Response surface METHODOLOGY
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Using of Key Stratum Theory to Study the Structural Development of Roof Aquifer 被引量:2
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作者 CHEN Li ZHANG Fawang +4 位作者 YAO Hongchao HAN Zhantao QIAN Long CHEN Liang JIANG Chengchao 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2015年第6期2091-2091,共1页
During the underground mining of coal resources,overlying rocks on the roof of excavated tunnels will be destroyed due to ground pressure,and as a result,part of them will break and fall into the tunnels.How to determ... During the underground mining of coal resources,overlying rocks on the roof of excavated tunnels will be destroyed due to ground pressure,and as a result,part of them will break and fall into the tunnels.How to determine the distribution of fractured areas and fissures presents a major problem for preserving the overlying aquifer. 展开更多
关键词 In Using of Key stratum theory to Study the Structural Development of Roof aquifer
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