IL-2 production and IL-2 receptor (Tac antigen) of the peripheral blood mononuclear cells in 30 patients with aplastic anemic (AA) were studied. We found that mononuclear cells from patients produce spontaneously IL-2...IL-2 production and IL-2 receptor (Tac antigen) of the peripheral blood mononuclear cells in 30 patients with aplastic anemic (AA) were studied. We found that mononuclear cells from patients produce spontaneously IL-2 in the absence of exogenous lee-tin stimulation, the proportion of Tac+ cells in mononuclear cells increased. The release of IL-2 and or Tac antigen expression were elevated in almost every patient with AA. The plasma from patients stimulate mitogen-induced blastogenesis and Tac antigen expression of normal human lymphocytes. Immunological 1 abnormalities of patients with AA possibly might represents secondary response to bone marrow depression.展开更多
Objective To investigate the relationship between the expression of histone acetylation enzyme 2(HDAC2),interleukin-8(IL-8),tumor necrosis factor-α(TNF-α)in lung adenocarcinoma tissues and smoking.Methods A total of...Objective To investigate the relationship between the expression of histone acetylation enzyme 2(HDAC2),interleukin-8(IL-8),tumor necrosis factor-α(TNF-α)in lung adenocarcinoma tissues and smoking.Methods A total of 73 cases of lung adenocarcinoma confirmed by pathological examination after surgical展开更多
91-95.Objective To investigate the expression of transcriptionfactor forkhead /winged helix transcription factor 3(Foxp3),immune factor transforming growth factor-beta1 (TGF-β1),and T-lymphocyte activation related fa...91-95.Objective To investigate the expression of transcriptionfactor forkhead /winged helix transcription factor 3(Foxp3),immune factor transforming growth factor-beta1 (TGF-β1),and T-lymphocyte activation related factorinterleukin-2 (IL-2) in peripheral blood of patients withcoal-burning arsenic poisoning,and to analyze the effectsof arsenic exposure on immune function. Methods Acase-control study was conducted to investigate 149 cases[94 males and 55 females,(50. 69 ± 6. 14) years old]of arsenic poisoning in Yuzhang coal-burning arsenic poisoningarea,southwestern Guizhou Province,and the caseswere diagnosed based on the“Diagnosis of EndemicArsenicosis”(WS /T 211-2015) and confirmed by clinicalreview. According to skin damage,the patients weredivided into mild arsenic poisoning group (39 cases),moderate arsenic poisoning group (54 cases) and severearsenic poisoning group ( 56 cases );and 41 cases[12 males and 29 females,(45. 76 ± 7. 88) years old]of non-arsenic exposed residents from 12 km of Yuzhangcoal-burning area were selected as control group. Morningurine and peripheral blood samples were collectedwith informed consent.展开更多
文摘IL-2 production and IL-2 receptor (Tac antigen) of the peripheral blood mononuclear cells in 30 patients with aplastic anemic (AA) were studied. We found that mononuclear cells from patients produce spontaneously IL-2 in the absence of exogenous lee-tin stimulation, the proportion of Tac+ cells in mononuclear cells increased. The release of IL-2 and or Tac antigen expression were elevated in almost every patient with AA. The plasma from patients stimulate mitogen-induced blastogenesis and Tac antigen expression of normal human lymphocytes. Immunological 1 abnormalities of patients with AA possibly might represents secondary response to bone marrow depression.
文摘Objective To investigate the relationship between the expression of histone acetylation enzyme 2(HDAC2),interleukin-8(IL-8),tumor necrosis factor-α(TNF-α)in lung adenocarcinoma tissues and smoking.Methods A total of 73 cases of lung adenocarcinoma confirmed by pathological examination after surgical
文摘91-95.Objective To investigate the expression of transcriptionfactor forkhead /winged helix transcription factor 3(Foxp3),immune factor transforming growth factor-beta1 (TGF-β1),and T-lymphocyte activation related factorinterleukin-2 (IL-2) in peripheral blood of patients withcoal-burning arsenic poisoning,and to analyze the effectsof arsenic exposure on immune function. Methods Acase-control study was conducted to investigate 149 cases[94 males and 55 females,(50. 69 ± 6. 14) years old]of arsenic poisoning in Yuzhang coal-burning arsenic poisoningarea,southwestern Guizhou Province,and the caseswere diagnosed based on the“Diagnosis of EndemicArsenicosis”(WS /T 211-2015) and confirmed by clinicalreview. According to skin damage,the patients weredivided into mild arsenic poisoning group (39 cases),moderate arsenic poisoning group (54 cases) and severearsenic poisoning group ( 56 cases );and 41 cases[12 males and 29 females,(45. 76 ± 7. 88) years old]of non-arsenic exposed residents from 12 km of Yuzhangcoal-burning area were selected as control group. Morningurine and peripheral blood samples were collectedwith informed consent.
