An investigation of the influence of intestinal flora in external traditional Chinese medicine therapy

External therapy,which has been used for millennia to treat disease,has now become the newest member of complementary and alternative therapies.A growing number of clinical studies and animal experiments have shown that external therapy exerts a positive effect on the intestinal flora.In this paper,we review the research related to external therapy on various systemic diseases and focus on changes in the intestinal flora.We found that studies on external therapy are dominated by acupuncture and tuina,primarily aimed at the treatment of digestive and neurological diseases.However,the deeper mechanism of regulation of the intestinal flora by external therapy has not yet been experimentally confirmed.

Analysis of effect of external therapies of traditional Chinese medicine on eczema by data mining

Objective:To determine medication regularity external therapies of Traditional Chinese medicine of eczema by data mining.Methods:Papers were retrieved from databases Pubmed,CNKI,WF,VIP,CBM,Web of Science and Embase.From the establishment of the database to April 2020 were searched.The main points of Medication Regularity were established with Excel 2016 software;the characteristics and laws in external therapies of Traditional Chinese medicine Treatment of eczema were analyzed with the relevance rule and cluster analysis Methods in data mining technology.Results:The property and flavor of the herbs mainly used were cold,bitter,while the channel which are mostly involved included liver meridian,lung meridian and Bladder Meridian,The analysis of association rules showed that kushen and difuzi had the highest correlation.The clustering analysis figured out 7groups of the herbs.Conclusion:The study presents the common pair herbs in the treatment of external therapies of Traditional Chinese medicine of eczema,which provides the approach to syndrome differentiation and medication in clinical treatment of eczema.

Research progress of external therapies of traditional Chinese medicine in the treatment of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease(NAFLD)is a common chronic liver disease characterized by diffuse hepatic steatosis.With the improvement of people's living standard,the incidence rate of NAFLD has been increasing,which has become one of the global health problems in 21st Century.However,there is no specific drug or standard treatment for NAFLD,which brings challenges to treatment.Acupuncture,moxibustion,massage and other external therapies based on the characteristics of traditional Chinese medicine have obvious curative effect in the clinical treatment of NAFLD,but the mechanism has not been systematically explained,which makes the clinical promotion evidence insufficient.This paper aims to summarize the researches on the treatment of NAFLD by external therapies of traditional Chinese medicine in recent years,and analyze its possible mechanism,so as to provide a scientific theoretical basis for future basic experiments and clinical research,and form a set of standardized clinical diagnosis and treatment scheme with the characteristics of traditional Chinese medicine.

Therapeutic Effect of Oral Administration and External Therapy of Traditional Chinese Medicine on Cervical Tuberculous Lymphadenopathy

Objective:To analyze the clinical effect and value of oral administration and external therapy of traditional Chinese medicine for treatment of cervical tuberculous lymphadenopathy.Methods:A total of 56 patients with cervical tuberculous lymphadenopathy admitted to our hospital from January 1 to January 2018 were recruited.By using double-blind method,the patients were divided into control group(n=28)and experimental group(n=28).Control group comprised of patients with conventional anti-tuberculosis treatment,while the experimental group comprised of patients treated with oral administration and external therapy of traditional Chinese medicine.Total effective rate,incidence of complication and level of T lymphocyte subsets were compared between the two groups of cervical tuberculous lymphadenopathy patients.Results:Post-treatment data of total effective rate,complication rate,CD3+,CD4+,CD8+,CD4+/CD8+of the experimental group were compared with the control group.P<0.05;statistical analysis showed statistical significance.Post-treatment data of CD3+,CD4+,CD8+,CD4+/CD8+of both control and experimental groups were compared with pre-treatment data.P<0.05;statistical analysis showed statistical significance.Conclusion:Oral administration and external therapy of traditional Chinese medicine possesses significant effect in treatment of cervical tuberculous lymphadenopathy.

The use of traditional Chinese medicine internally and externally combined with auricular acupuncture point bloodletting in the treatment of vulvar leukoplakia

Vulvar leukoplakia refers to the chronic disease of degeneration and hypopigmentation of the skin and mucous membrane of the vulva with unbearable itching in women, seriously affecting the quality of life. The main treatment of western medicine for vulvar leukoplakia is the external use of glucocorticoids or estrogen, resulting to the high recurrence rate and side effects. Traditional Chinese medicine (TCM) has the characteristics of the overall concept and dialectical treatment with a variety of ways. Literature review in recent years found that the treatment of TCM decoction combined with external therapies, such as external fumigation, acupuncture and other treatments, or the combination of TCM decoction and external western medicine hormone ointment, can obtain good effects in vulvar leukoplakia. During the clinical practice, we found that the use of TCM internally and externally combined with auricular acupuncture point bloodletting was highly effective with unique advantages in the treatment of vulvar leukoplakia, providing the ideas guidance for clinicians.

Research progress in the treatment of diabetic foot with traditional Chinese medicine

Diabetic foot is one of the chronic complications of diabetes,which is serious and expensive to treat.As an effective method for treating diabetic foot,Chinese medicine plays an important role in improving the clinical symptoms and reducing the suffering of diabetic foot patients.The methods of traditional Chinese medicine to treat diabetic foot include internal treatment method,external treatment method and comprehensive therapy.This article reviews the research results of traditional Chinese medicine treatment of diabetic foot in order to provide reference for the treatment of diabetic foot.

Study of the similarities and differences between TCM and Tujia medicine in clinical diagnosis and treatment of liver cancer

目前国内对于肝癌的治疗已经不仅仅局限于西医的放化疗。随着中国传统医学的发展,更多的患者选择中医进行保守治疗。中医作为我国传统医学,具有完善的理论体系及诊疗体系。土家族医学作为中华民族医学的一个分支,在疾病治疗方面拥有其独特的诊疗手段。在探索肝癌诊疗时,笔者发现,中医与土家医在治疗肝癌时具有异曲同工之效,故进行对比性整理与研究,以期为诊疗肝癌提供参考与借鉴。

Technical operation specification for pricking-cupping therapy

Pricking-cupping therapy is a Traditional Chinese Medicine(TCM)nursing technology that can adjust the viscera of the human body,make the meridians smooth,and Yin and Yang balanced mainly by means of relieving heat and detoxification,harmonizing Qi and blood,promoting blood circulation and removing blood stasis,dredging meridians and activating collaterals,reducing swelling and pain,purging heat and calming shock,clearing heat,and opening orifices.Pricking-cupping therapy has a long history and wide application.After thousands of years of development,it has made great progress.They are widely used to treat lumbar disc herniation,herpes zoster,acute arthritis,migraine,and other diseases in China.Through the clinical practice and theoretical exploration of physicians of past dynasties,the therapeutic mechanism and application scope of pricking-cupping therapy have been greatly enriched.Modern TCM practitioners have conducted in-depth researches on the operation norms of the therapy on the basis of the ancients,hoping to grasp the essence of the disease more accurately and make the rational use of the operation technology of the therapy.

中医适宜技术联合盆底肌肉训练治疗产后压力性尿失禁临床观察

目的 对产后压力性尿失禁患者进行中医适宜技术干预治疗,并观察效果。方法 将60例患者随机分为治疗组和训练组,并对其进行相应治疗,观察2组1 h尿垫试验结果、Sandvik尿失禁指数和国际尿失禁咨询委员会尿失禁问卷简表(ICI-Q-SF)评分改善情况,以及临床疗效。结果 治疗后,治疗组1 h尿垫试验结果、Sandvik尿失禁指数和ICI-Q-SF评分改善均优于训练组。治疗结束时,治疗组总有效率为86.7%(26/30),高于对照组的63.3%(19/30)(P<0.05)。6个月随访时治疗组总有效率86.7%(26/30)亦高于对照组的56.7%(17/30)(P<0.05)。结论 在产后女性中,压力性尿失禁的发生是值得关注的问题。将中医适宜技术与凯格尔训练联用干预产后压力性尿失禁达到巩固、延长疗效的目的。

散结透脓方外敷联合消肿清热解毒汤内服治疗泛发性肛周脓肿术后的效果及对创面愈合时间、肛门功能的影响

目的观察散结透脓方外敷联合消肿清热解毒汤内服在泛发性肛周脓肿术后的应用效果及对创面愈合时间、肛门功能的影响。方法将102例热毒炽盛型泛发性肛周脓肿术后患者按照随机数字表法分为2组,对照组51例术后予以抗感染及对症支持等治疗方法,治疗组51例在对照组基础上予以散结透脓方外敷联合消肿清热解毒汤内服治疗,2组均治疗4周。比较2组治疗后创面愈合情况(创面腐肉脱落时间、创面愈合时间、治疗2周创面回缩率)、治疗前后中医证候评分、治疗前和治疗2周疼痛视觉模拟评分(VAS)、治疗前和术后2个月肛门失禁Wexner评分量表评分、治疗前和治疗2周炎症相关指标[白细胞计数(WBC)、C反应蛋白(CRP)、白细胞介素6(IL-6)],并统计2组临床疗效,记录治疗期间不良反应发生情况。结果治疗组总有效率90.20%(46/51),对照组总有效率74.51%(38/51),治疗组临床疗效优于对照组(P<0.05)。2组治疗后中医证候各项评分均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。治疗组创面腐肉脱落时间、愈合时间均低于对照组(P<0.05),治疗2周时创面回缩率高于对照组(P<0.05)。2组治疗2周时疼痛VAS均较本组治疗前降低(P<0.05),且治疗组治疗2周时疼痛VAS低于对照组同期(P<0.05)。2组术后2个月Wexner评分均较本组治疗前降低(P<0.05),且治疗组术后2个月Wexner评分低于对照组同期(P<0.05)。2组治疗2周后外周血WBC、CRP、IL-6水平均较本组治疗前降低(P<0.05),且治疗组治疗2周后均低于对照组同期(P<0.05)。结论散结透脓方外敷联合消肿清热解毒汤内服可提高泛发性肛周脓肿术后疗效,缩短愈合时间,减轻术后疼痛,缓解炎症反应,有利于改善患者肛门功能。

下肢洗剂治疗膝骨关节炎临床观察

目的探讨下肢洗剂治疗膝骨关节炎的效果。方法选择60例膝骨关节炎患者作为研究对象,将其随机分成试验组和对照组,各30例。对照组给予双氯芬酸二乙胺乳胶剂外用,试验组给予下肢洗剂外用,2组均持续治疗2周。观察2组的临床疗效,比较2组治疗前后西安大略大学和麦克马斯特大学骨关节炎指数(WOMAC)量表评分、膝关节综合评分、血清学指标变化情况,以及不良反应发生情况。结果试验组的愈显率为66.67%(20/30),高于对照组的50.00%(15/30),差异有统计学意义(P<0.05)。治疗后,2组患者的WOMAC量表评分、膝关节综合评分及白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)水平均有不同程度下降,且试验组下降程度大于对照组,差异有统计学意义(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论下肢洗剂对于阳虚寒凝型膝骨关节炎具有治疗作用,可以很好地改善其临床症状,使血清炎性因子水平降低,在临床有一定的应用推广价值。

灸刺放血联合治疗椎动脉型颈椎病急性发作期临床观察

目的 观察灸刺放血联合治疗椎动脉型颈椎病急性发作期的临床效果。方法 将70例椎动脉型颈椎病急性发作期患者随机分成观察组(灸刺放血结合组)和对照组(灸刺结合组),各35例。观察组予电子灸、普通针刺及刺络放血拔罐疗法,对照组给予电子灸及普通针刺法联合治疗;于首次治疗前后行椎-基底动脉血流动力学[脑血管彩色多普勒超声(TCD)]测定及对眩晕程度进行评估对比。结果 治疗后,TCD显示2组患者收缩峰期血流速度(Vs)、平均血流速度(Vm)均降低(P<0.01),且2组比较,差异有统计学意义(P<0.05)。但2组血管搏动指数(PI)、血管阻力指数(RI)无改善(P>0.05)。治疗后,2组眩晕程度均好转(P<0.01),且2组比较,差异有统计学意义(P<0.05)。结论 灸刺放血结合疗法能够有效减慢椎动脉型颈椎病急性发作期患者的椎-基底动脉高血流速度、缓解眩晕程度,即时效果明显优于针刺艾灸结合组,可在各级医疗机构推广应用。

中药外敷联合复合超声关节治疗仪治疗膝骨关节炎的临床效果

目的探究中药外敷联合复合超声关节治疗仪在膝骨关节炎(KOA)中的应用效果。方法选取2022年8月至2023年8月就诊于安阳市中医院的99例KOA患者为研究对象,随机分为3组,每组33例。超声组接受超声关节治疗仪治疗,中药组接受中药外敷治疗,联合组接受中药外敷联合超声关节治疗仪治疗。对比3组疗效及治疗前后西安大略和麦克马斯特大学骨关节炎指数(WOMAC)、视觉模拟评分法(VAS)、奎森功能演算(Lequesne)指数评分、成纤维细胞生长因子2(FGF-2)、Ⅰ型胶原C-末端肽(CTX-I)、软骨寡聚基质蛋白(COMP)及不良反应。结果联合组总有效率[93.94%(31/33)]高于超声组[75.76%(25/33)]、中药组[72.73%(24/33)](P<0.05),超声组与中药组总有效率对比,差异无统计学意义(P>0.05);治疗3个疗程后联合组FGF-2高于超声组、中药组,CTX-1、COMP、Lequesne、WOMAC评分低于超声组、中药组(P<0.05),超声组、中药组组间对比,差异无统计学意义(P>0.05);治疗3个疗程后联合组静态、动态VAS评分<中药组<超声组(P<0.05);治疗期间3组均未出现不良反应。结论中药外敷与复合超声关节治疗仪联合治疗KOA患者效果确切,可有效调节骨代谢指标,有助于缓解患者疼痛感,恢复膝关节功能。

吴氏理筋手法结合J型针刀治疗术后肘关节僵硬的临床研究

目的 探讨吴氏理筋手法结合J型针刀治疗术后肘关节僵硬的临床应用价值。方法 选取江西省南昌市洪都中医院康复科2020年6月—2021年6月收治的60例术后肘关节僵硬患者,以单盲随机法分为对照组(关节松动术)与治疗组(吴氏理筋手法结合J型针刀),各30例。治疗4周后,比较两组Mayo肘关节功能评分(MEPS)与视觉模拟量表(VAS)评分,同时对疗效开展评估。结果 治疗后,与对照组相比,治疗组MEPS评分较高,而VAS评分较低(P<0.05);且治疗组总有效率为100.00%(30/30),明显高于对照组的83.33%(25/30)(P<0.05)。结论 吴氏理筋手法结合J型针刀治疗术后肘关节僵硬患者,能实现肘关节功能的恢复,并减轻患者疼痛,效果确切,具有较高的推广价值。

中医外治法治疗乳腺癌相关淋巴水肿研究进展

乳腺癌相关淋巴水肿(BCRL)是乳腺癌术后常见并发症,其发展迅速,如若不及时治疗,严重者可导致肌肉疼痛和肩肘关节功能永久丧失。中医药为中华民族主流医学,是历代医学家通过不断实践而传承下来的文化瑰宝,众多研究表明其防治BCRL效果显著,具有独特优势。故文章从中药外用、针灸推拿、耳穴压豆、刺络拔罐4个角度,对中医药外治法在防治BCRL中的研究进展进行系统性总结,也为BCRL的后续相关研究提供理论依据。

火针疗法联合消疮散中药面膜治疗面部寻常痤疮的疗效观察

目的:观察火针疗法联合消疮散中药面膜治疗面部寻常痤疮的临床疗效和安全性。方法:选取面部寻常痤疮患者66例,根据纳入标准制定随机对照表,随机分为治疗组(针药联合)和对照组(火针),治疗后,两组实际各纳入31例、32例。火针治疗每周1次,中药面膜治疗隔日1次,疗程均为4周,分别于治疗第2周末、第4周末进行疗效判定,并记录治疗过程中发生的不良反应,疗程结束后1个月对患者进行回访。结果:治疗2周后,两组患者的皮损评分均低于治疗前(P<0.05)。且治疗4周后,治疗组皮损评分低于对照组(P<0.05)。治疗组总有效率96.77%,高于对照组的78.13%(P<0.05)。结论:火针疗法联合消疮散中药面膜治疗面部寻常痤疮疗效确切,安全性高,临床可推广应用。

推拿不同部位对孤独症谱系障碍模型鼠行为学及肠道菌群的影响

目的探究不同部位的推拿对丙戊酸(VPA)诱导的孤独症谱系障碍(ASD)模型鼠行为学和肠道菌群的影响。方法将20只怀孕12.5天的Sprague Dawley(SD)雌性大鼠随机分为VPA模型组[腹腔注射VPA(600 mg/kg),n=15]和生理盐水组(腹腔注射等量生理盐水,n=5)。将注射生理盐水的子代雄鼠作为对照组,将注射VPA的子代雄鼠随机分为VPA组、背部组和腹部组(n=7)。在出生后第21天,通过三箱社交、旷场实验和埋珠实验观察四组大鼠的社交能力、焦虑行为和刻板行为,并开始对背部组和腹部组进行推拿,每天2次,持续14天。第35天,再次进行行为学检测,并取肠道内容物进行物种组成与结构分析、标志物种与差异物种分析。结果(1)行为学结果显示,与VPA组相比,背部组大鼠社交时间和旷场中心区运动时间显著增加(P<0.05),埋珠数量明显减少(P<0.01),说明其社交、焦虑和刻板行为得到改善;与VPA组相比,腹部组大鼠埋珠数量显著减少(P<0.05),刻板行为改善;埋珠实验中,背部组较腹部组埋珠数量更少,刻板行为改善更显著(P<0.05),而三箱社交和旷场实验两组结果无显著差异(P>0.05)。(2)肠道微生物检测结果显示,在多样性分析中,与VPA组相比,背部组和腹部组肠道菌群丰富度显著增加(P<0.05),多样性增加(背部组P<0.05,腹部组P<0.01);在差异性分析中,在门水平上,与VPA组相比,腹部组厚壁菌门相对丰度呈现较为明显的降低趋势(P<0.05);在属水平上,与VPA组相比,背部组和腹部组的乳杆菌属相对丰度较VPA组显著下降(P<0.05);标志物种分析中,与VPA组相比,背部组布劳特氏菌属显著增加(P<0.05)。结论推拿能对ASD模型大鼠行为学和肠道菌群结构产生影响;推拿背部对ASD模型鼠的社交能力、焦虑行为和刻板行为疗效显著,推拿腹部仅对刻板行为有明显效果;推拿背部与推拿腹部均使ASD模型鼠肠道菌群丰富度和多样性增加,其中推拿腹部对肠道微生物多样性的改善更显著,并使物种分布更均匀。

蒙医外治法的研究进展

蒙医药学是祖国传统医学的重要组成部分,是在蒙古族人民长期的医疗实践中,吸收中医、藏医等医学理论,并在蒙古特色地域、饮食、文化下逐渐形成与发展起来的民族特色医学。蒙医药学中,外治法特色突出,可分药物外治法和非药物外治法2个角度对蒙医外治法进行探讨,从药浴、外敷、吹药、含漱4个方面对蒙医药物外治法进行分析,从震脑术、灸法、针刺、刮痧、放血、整骨、腹罨、萨木那哈疗法8个方面对蒙医非药物外治法进行分析。通过综合分析,比较蒙医外治法与中医外治法的异同,对蒙医外治法的发展进行探讨。

微波照射联合中药外敷治疗骨折术后切口愈合不良的临床观察

目的探究微波照射联合中药外敷治疗骨折术后切口愈合不良的临床效果。方法采用回顾性观察性研究,选取2019年1月—2020年6月江西中医药大学附属医院骨科收治的43例骨折术后切口愈合不良患者。其中对照组20例,运用西医治疗;研究组23例,在对照组的基础上行中药外敷联合微波照射治疗。比较两组患者的切口愈合时间、切口愈合等级、视觉模拟量表(VAS)评分、不良反应发生率及血清C-反应蛋白(CRP)、白细胞(WBC)、降钙素原(PCT)水平变化。结果研究组患者术后切口愈合时间显著短于对照组,切口愈合等级显著优于对照组(P<0.05)。治疗后,两组患者VAS评分均低于治疗前,且研究组低于对照组(P<0.05);两组患者治疗3 d后、治疗7 d后血清CRP、WBC、PCT表达均低于治疗前,且同时间节点研究组低于对照组(P<0.05)。两组患者治疗期间均未出现不良反应。结论微波照射联合中药外敷治疗骨折术后切口愈合不良的效果确切,值得临床推广应用。

超声引导下针刀松解疗法用于肩峰下撞击综合征临床观察

目的探讨超声引导下针刀松解疗法对肩峰下撞击综合征(SIS)患者的临床效果。方法纳入80例临床期SIS患者,按照随机数字表法分为观察组(行超声引导下针刀松解疗法)40例及对照组(行常规针刺)40例,对照组单纯针刺治疗,观察组在对照组的基础上行超声实时引导下针刀松解疗法。记录2组总体临床疗效,治疗前后视觉模拟量表(VAS)评分、Constant肩关节评分,治疗前后三大常规、肝功能、电解质、心电图检查结果等安全性指标。结果观察组的总有效率为95.00%(38/40),显著高于对照组的85.00%(34/40)(P<0.05);观察组VAS评分、Constant肩关节评分均低于对照组(P<0.05);2组安全性指标均未见明显异常。结论经临床对比,超声引导下针刀松解疗法用于SIS在总体临床疗效、VAS评分、Constant肩关节评分方面较常规针刺疗法更优。