目的:探讨A型肉毒毒素(Botulinum toxin type A,BTX-A)联合眶隔膜张力重建术整复松弛型下睑袋临床效果。方法:选取2020年12月-2022年12月在笔者医院治疗的松弛型下睑袋就医者为研究对象,共87例。根据治疗方法分为实验组(n=47)和对照组(n...目的:探讨A型肉毒毒素(Botulinum toxin type A,BTX-A)联合眶隔膜张力重建术整复松弛型下睑袋临床效果。方法:选取2020年12月-2022年12月在笔者医院治疗的松弛型下睑袋就医者为研究对象,共87例。根据治疗方法分为实验组(n=47)和对照组(n=40),实验组行BTX-A联合眶隔膜张力重建术,对照组行眶隔膜张力重建术,术后对就医者进行随访,比较下睑袋术后效果、泪沟畸形(Barton分级)、术后外观满意度、手术并发症。结果:治疗后,实验组瘢痕宽度、VSS低于对照组(P<0.05),手术时间及切口恢复时间与对照组比较,差异无统计学意义(P>0.05);两组就医者Barton分级均有所改善,且实验组0级和1级(95.74%)高于对照组(82.50%)(P<0.05);治疗后,实验组满意度(95.74%)高于对照组(80.00%)(P<0.05);治疗后,实验组与对照组并发症发生率比较,差异无统计学意义(P>0.05)。结论:BTX-A联合眶隔膜张力重建术整复松弛型下睑袋,能够有效消除下睑袋,减少瘢痕增生,改善Barton分级构成,就医者外观满意度较高。展开更多
AIM:To investigate the clinical characteristics and prognosis of patients with malignant eyelid tumors.·METHODS:This was a retrospective,non-randomized,clinical reviews.Between January,2002 and December,2011,75 c...AIM:To investigate the clinical characteristics and prognosis of patients with malignant eyelid tumors.·METHODS:This was a retrospective,non-randomized,clinical reviews.Between January,2002 and December,2011,75 cases with histologically confirmed malignant eyelid tumors were evaluated.Patients’ charts were reviewed for clinical information,treatment procedure,and disease course.Survival analysis in terms of recurrence-free survival was performed using age,sex,location of tumor and histopathological type.The followup ranged from 1 to 78 months(mean=21 months).·RESULTS:The 75 eyelid tumors included 35 basal cell carcinoma(BCC,46.7%),22 sebaceous gland carcinoma(SGC,29.3%),7 squamous cell carcinoma(SCC,9.3%),10 malignant melanoma(MM,13.3%),and 1 Merkel cell carcinoma(MCC,1.3%).Recurrence developed in 17cases(22.7%).The recurrence rate of BCC(4/35,11.4%)was significant lower than MM(6/10,60.0%,P 【0.001).The mean interval of recurrence was 21 months(range 3-62) for all eyelid tumors.Tumor located at canthus had higher recurrence rate(50%) compared with those located at eyelid(19%,P 【0.05).Histological type was independent variable for recurrence by Cox regression analysis.·CONCLUSION:It is important to achieve a negative tumor margin in canthus located malignant eyelid tumor.Clinicians should have a high level of suspicion for recurrence according to histological type when treating patients with eyelid tumor.展开更多
文摘目的:探讨A型肉毒毒素(Botulinum toxin type A,BTX-A)联合眶隔膜张力重建术整复松弛型下睑袋临床效果。方法:选取2020年12月-2022年12月在笔者医院治疗的松弛型下睑袋就医者为研究对象,共87例。根据治疗方法分为实验组(n=47)和对照组(n=40),实验组行BTX-A联合眶隔膜张力重建术,对照组行眶隔膜张力重建术,术后对就医者进行随访,比较下睑袋术后效果、泪沟畸形(Barton分级)、术后外观满意度、手术并发症。结果:治疗后,实验组瘢痕宽度、VSS低于对照组(P<0.05),手术时间及切口恢复时间与对照组比较,差异无统计学意义(P>0.05);两组就医者Barton分级均有所改善,且实验组0级和1级(95.74%)高于对照组(82.50%)(P<0.05);治疗后,实验组满意度(95.74%)高于对照组(80.00%)(P<0.05);治疗后,实验组与对照组并发症发生率比较,差异无统计学意义(P>0.05)。结论:BTX-A联合眶隔膜张力重建术整复松弛型下睑袋,能够有效消除下睑袋,减少瘢痕增生,改善Barton分级构成,就医者外观满意度较高。
基金National Natural Science Foundation of China (No.81070756)National "Twelfth Five-Year" Plan for Science and Technology Support Program (No.2012BAI08B01)+1 种基金Zhejiang Key Innovation Team Project of China (No.2009R50039)Zhejiang Key Laboratory Fund of China (No.2011E10006)
文摘AIM:To investigate the clinical characteristics and prognosis of patients with malignant eyelid tumors.·METHODS:This was a retrospective,non-randomized,clinical reviews.Between January,2002 and December,2011,75 cases with histologically confirmed malignant eyelid tumors were evaluated.Patients’ charts were reviewed for clinical information,treatment procedure,and disease course.Survival analysis in terms of recurrence-free survival was performed using age,sex,location of tumor and histopathological type.The followup ranged from 1 to 78 months(mean=21 months).·RESULTS:The 75 eyelid tumors included 35 basal cell carcinoma(BCC,46.7%),22 sebaceous gland carcinoma(SGC,29.3%),7 squamous cell carcinoma(SCC,9.3%),10 malignant melanoma(MM,13.3%),and 1 Merkel cell carcinoma(MCC,1.3%).Recurrence developed in 17cases(22.7%).The recurrence rate of BCC(4/35,11.4%)was significant lower than MM(6/10,60.0%,P 【0.001).The mean interval of recurrence was 21 months(range 3-62) for all eyelid tumors.Tumor located at canthus had higher recurrence rate(50%) compared with those located at eyelid(19%,P 【0.05).Histological type was independent variable for recurrence by Cox regression analysis.·CONCLUSION:It is important to achieve a negative tumor margin in canthus located malignant eyelid tumor.Clinicians should have a high level of suspicion for recurrence according to histological type when treating patients with eyelid tumor.
