A series of novel and easily accessed ferrocene-based amino-phosphine-sulfonamide （f-Amphamide） ligands have been developed and ap- plied in Ir-catalyzed asymmetric hydrogenation of aryl ketones, affording the corre...A series of novel and easily accessed ferrocene-based amino-phosphine-sulfonamide （f-Amphamide） ligands have been developed and ap- plied in Ir-catalyzed asymmetric hydrogenation of aryl ketones, affording the corresponding chiral secondary alcohols with excellent results （up to 〉99% conversion, 〉99% ee and TON up to 200 000）. DFT calculations suggest an activating model involving an alkali cation Li.展开更多
文摘A series of novel and easily accessed ferrocene-based amino-phosphine-sulfonamide （f-Amphamide） ligands have been developed and ap- plied in Ir-catalyzed asymmetric hydrogenation of aryl ketones, affording the corresponding chiral secondary alcohols with excellent results （up to 〉99% conversion, 〉99% ee and TON up to 200 000）. DFT calculations suggest an activating model involving an alkali cation Li.
