速度、技艺与感知:意大利文艺复兴艺术理论中的Facilità

本文通过对意大利文艺复兴艺术文献的研究,以视觉艺术术语“facilita”为中心,呈现术语在艺术实践中的衍义。本文首先追溯词语从修辞学进入艺术理论的方式,发现艺术术语“facilita”在英译与中译中“速度”含义的来源。进一步借由两位文艺复兴艺术理论作者瓦萨里与多尔切的争论,讨论“facilita”与不同绘画媒介湿壁画、油画的联系,其被讨论的背后是不同艺术中心与不同艺术批评体系的竞争。最终理解其与画布“表面”的关系,以及其“隐藏之艺”与感动观众的多重性质。

Sex-specific facilitation and reproduction of the gynodioecious cushion plant Arenaria polytrichoides on the Himalaya-Hengduan mountains,SW China

When benefiting other beneficiaries,cushion plants may reciprocally receive feedback effects.The feedback effects on different sex morphs,however,remains unclear.In this study,taking the gynodioecious Arenaria polytrichiodes as a model species,we aimed to assess the sex-specific facilitation intensity of cushion plant by measuring the beneficiary cover ratio,and to assess the potential costs in cushion reproductive functions by measuring the flower and fruit cover ratios.The total beneficiary cover ratio was similar between females and hermaphrodites.Females produced much less flowers but more fruits than hermaphrodites.These results suggested that females and hermaphrodites possess similar facilitation intensity,and female cushion A.polytrichoides may allocate more resources saved from pollen production to seed production,while hermaphrodites possibly allocate more resources to pollen production hence reducing seed production.The surface areas covered by beneficiaries produced less flowers and fruits than areas without beneficiaries.In addition,strong negative correlations between beneficiary cover and flower cover were detected for both females and hermaphrodites,but the correlation strength were similar for these two sex morphs.However,the correlation between beneficiary cover and fruit cover was only significantly negative for females,suggesting that beneficiary plants negatively affect fruit reproduction of females while have neutral effects on hermaphrodites.All the results suggest that to facilitate other beneficiaries can induce reproductive costs on cushion A.polytrichoides,with females possibly suffering greater cost than hermaphrodites.Such differentiation in reproductive costs between sex morphs,in long-term perspective,may imply sex imbalance in population dynamics.

Encroachment drives facilitation at alpine shrublines

Ongoing encroachment is driving recent alpine shrubline dynamics globally,but the role of shrub-shrub interactions in shaping shrublines and their relationships with stem density changes remain poorly understood.Here,the size and age of shrubs from 26 Salix shrubline populations along a 900-km latitudinal gradient(30°-38°N)were measured and mapped across the eastern Tibetan Plateau.Point pattern analyses were used to quantify the spatial distribution patterns of juveniles and adults,and to assess spatial associations between them.Mean intensity of univariate and bivariate spatial patterns was related to biotic and abiotic variables.Bivariate mark correlation functions with a quantitative mark(shrub height,basal stem diameter,crown width)were also employed to investigate the spatial relationships between shrub traits of juveniles and adults.Structural equation models were used to explore the relationships among conspecific interactions,patterns,shrub traits and recruitment dynamics under climate change.Most shrublines showed clustered patterns,suggesting the existence of conspecific facilitation.Clustered patterns of juveniles and conspecific interactions(potentially facilitation)tended to intensify with increasing soil moisture stress.Summer warming before 2010 triggered positive effects on population interactions and spatial patterns via increased shrub recruitment.However,summer warming after2010 triggered negative effects on interactions through reduced shrub recruitment.Therefore,shrub recruitment shifts under rapid climate change could impact spatial patterns,alter conspecific interactions and modify the direction and degree of shrublines responses to climate.These changes would have profound implications for the stability of alpine woody ecosystems.

Interaction of major facilitator superfamily domain containing 2A with the blood-brain barrier

The functional and structural integrity of the blood-brain barrier is crucial in maintaining homeostasis in the brain microenvironment;however,the molecular mechanisms underlying the formation and function of the blood-brain barrier remain poorly understood.The major facilitator superfamily domain containing 2A has been identified as a key regulator of blood-brain barrier function.It plays a critical role in promoting and maintaining the formation and functional stability of the blood-brain barrier,in addition to the transport of lipids,such as docosahexaenoic acid,across the blood-brain barrier.Furthermore,an increasing number of studies have suggested that major facilitator superfamily domain containing 2A is involved in the molecular mechanisms of blood-brain barrier dysfunction in a variety of neurological diseases;however,little is known regarding the mechanisms by which major facilitator superfamily domain containing 2A affects the blood-brain barrier.This paper provides a comprehensive and systematic review of the close relationship between major facilitator superfamily domain containing 2A proteins and the blood-brain barrier,including their basic structures and functions,cross-linking between major facilitator superfamily domain containing 2A and the blood-brain barrier,and the in-depth studies on lipid transport and the regulation of blood-brain barrier permeability.This comprehensive systematic review contributes to an in-depth understanding of the important role of major facilitator superfamily domain containing 2A proteins in maintaining the structure and function of the blood-brain barrier and the research progress to date.This will not only help to elucidate the pathogenesis of neurological diseases,improve the accuracy of laboratory diagnosis,and optimize clinical treatment strategies,but it may also play an important role in prognostic monitoring.In addition,the effects of major facilitator superfamily domain containing 2A on blood-brain barrier leakage in various diseases and the research progress on cross-blood-brain barrier drug delivery are summarized.This review may contribute to the development of new approaches for the treatment of neurological diseases.

Impact of BRICS Trade Facilitation on China's Exports Using Cross-Border E-Commerce

With the rapid growth of the global digital economy, cross-border e-commerce, as an emerging form of trade, has gradually become a powerful engine to promote the development of global trade. BRICS is an important force in the global economy, and the progress of the BRICS countries' trade facilitation level has an important impact on the global trade environment. This paper conducts an in-depth study of the dynamic changes in BRICS trade facilitation from 2013 to 2022, and uses an extended gravity model to analyze the specific impact of this change on China's exports using cross-border e-commerce. The results show that although the BRICS countries have made some progress in trade facilitation, the overall level still needs to be improved, and there are obvious differences among member countries. However, the improvement of trade facilitation among BRICS countries has undoubtedly brought significant positive effects to China's exports using cross-border e-commerce.

The Influence of the Implementation of Trade Facilitation Systems on the Time Required for Creating Delivery Orders: A Case Study of Tema Port

This study evaluated the impact of Ghana’s Integrated Customs Management System (ICUMS), implemented within the National Single Window initiative, on the efficiency of issuing Delivery Orders (DO) at Tema Port. Filling a gap in the existing literature, the research employed a quantitative approach to assess a specific time-related aspect of the cargo clearance process. Employing an Independent t-test on a dataset spanning 2026 Delivery Orders (924 pre-ICUMS and 1102 post-ICUMS) from July 2020 to July 2023, the study investigated ICUMS’s effectiveness in reducing DO issuance time. Results indicate a noteworthy decrease in average DO issuance time, from 11 days pre-implementation to approximately 9 days post-implementation, a reduction validated by statistical analysis through the independent t-test. In light of these findings, the study recommends ongoing refinement of the implementation, reinforcement of trade facilitation measures, and the adoption of best practices from successful global ports. Continuous stakeholder training and regular assessments of ICUMS performance are also endorsed. The study’s implications support the theoretical framework for Single Window systems and carry significant policy implications, emphasizing the need for collaborative efforts to streamline trade facilitation processes driven by Information Technology. Practically, the results serve as a management tool for stakeholders, highlighting areas for targeted interventions to reduce DO issuance times. Methodologically, this research contributes by applying robust statistical analysis to a specific component within the Time Release Study framework, offering a nuanced understanding of trade facilitation systems’ effectiveness in improving cargo clearance processes.

Facilitation of controllable excitation in Rydberg atomic ensembles

Strongly-interacting Rydberg atomic ensembles have shown intense collective excitation effects due to the inclusion of single Rydberg excitation shared by multiple atoms in the ensemble.In this paper we investigate a counter-intuitive Rydberg excitation facilitation with a strongly-interacting atomic ensemble in the strong probe-field regime,which is enabled by the role of a control atom nearby.Differing from the case of a single ensemble,we show that,the control atom's excitation adds to a second two-photon transition onto the doubly-excited Rydberg state,arising an excitation facilitation for the ensemble atoms.Our numerical studies depending on the method of quantum Monte Carlo wave function,exhibit the observation constraints of this excitation facilitation effect under practical experimental conditions.The results obtained can provide a flexible control for the excitation of Rydberg atomic ensembles and participate further uses in developing mesoscopic Rydberg gates for multiqubit quantum computation.

Invariant measures for the strong-facilitated exclusion process

Consider a generalized model of the facilitated exclusion process, which is a onedimensional exclusion process with a dynamical constraint that prevents the particle at site x from jumping to x+1 (or x-1) if the sites x-1, x-2 (or x+1, x+2) are empty. It is nongradient and lacks invariant measures of product form. The purpose of this paper is to identify the invariant measures and to show that they satisfy both exponential decay of correlations and equivalence of ensembles. These properties will play a pivotal role in deriving the hydrodynamic limit.

Open visitation in the NICU:nurses’perspectives on barriers and facilitators

Objective:This study aimed to investigate the nurses’perspectives on open family visitation and its barriers and facilitators in neonatal intensive care units(NICUs).Methods:This is a descriptive,cross-sectional study.A total of 113 nurses employed in 3 main NICUs of Tabriz participated in the study through the census sampling method.Nurses’perspectives on open visitation and its facilitators and barriers were assessed and analyzed using the Beliefs and Attitudes toward Visitation in NICU Questionnaire(BAVNIQ)and descriptive and analytical statistics,respectively.Results:Approximately 74%of the nurses who participating in the study had a moderate perspective on open visitation.From the nurses’viewpoint,“Parents’low awareness of sensitivity and hygienic principles of the NICU”was the first(90.3%)barrier,and the 2 factors,namely,“physical structure of the ward/lack of sufficient space”and“far distance between family’s residence and the hospital/having another child,”were the second(86.8%)barrier with an equal percentage.Among the facilitating factors,“Supporting employed parents during the neonate’s hospitalization”and“providing facilities for family accommodation in the hospital”were the first(82.3%)and the second(79.6%)facilitators,respectively,for open visitation.Conclusions:The majority of NICU nurses had a moderate perspective on the family open visitation.This reluctance seems to be originated mainly from the factors inhibiting open visitation,making its implementation challenging for nurses.The perspective of the frontline staff in caring for vulnerable infants on facilitators and barriers to open visitation may help policymakers,managers,and relevant officials in decision-making and implementing new visiting policies in the NICUs.

No effect of invasive tree species on aboveground biomass increments of oaks and pines in temperate forests

Prunus serotina and Robinia pseudoacacia are the most widespread invasive trees in Central Europe.In addition,according to climate models,decreased growth of many economically and ecologically important native trees will likely be observed in the future.We aimed to assess the impact of these two neophytes,which differ in the biomass range and nitrogen-fixing abilities observed in Central European conditions,on the relative aboveground biomass increments of native oaks Qucrcus robur and Q.petraea and Scots pine Pinus sylvestris.We aimed to increase our understanding of the relationship between facilitation and competition between woody alien species and overstory native trees.We established 72 circular plots(0.05 ha)in two different forest habitat types and stands varying in age in western Poland.We chose plots with different abundances of the studied neophytes to determine how effects scaled along the quantitative invasion gradient.Furthermore,we collected growth cores of the studied native species,and we calculated aboveground biomass increments at the tree and stand levels.Then,we used generalized linear mixed-effects models to assess the impact of invasive species abundances on relative aboveground biomass increments of native tree species.We did not find a biologically or statistically significant impact of invasive R.pseudoacacia or P.serotina on the relative aboveground,biomass increments of native oaks and pines along the quantitative gradient of invader biomass or on the proportion of total stand biomass accounted for by invaders.The neophytes did not act as native tree growth stimulators but also did not compete with them for resources,which would escalate the negative impact of climate change on pines and oaks.The neophytes should not significantly modify the carbon sequestration capacity of the native species.Our work combines elements of the per capita effect of invasion with research on mixed forest management.

Enhancing CO_(2) transport with plasma-functionalized ionic liquid membranes

The ionic liquid(IL) 1-butyl-3-methylimidazolium tetrafluoroborate treated with radiofrequency plasma is proposed for functionalization and immobilization on polyethersulfone supports to form supported ionic liquid membranes for CO_(2) separation.The effects of treatment time and transmembrane pressure difference on CO_(2) permeance were evaluated.The best gas permeation performance was obtained with a treatment time of 10 min and the transmembrane pressure difference was 0.25 MPa.Characterization of the materials by Fourier transform infrared spectroscopy,x-ray photoelectron spectroscopy and nuclear magnetic resonance spectroscopy demonstrates that the IL is grafted with carboxyl groups and deprotonated through plasma treatment.A preliminary mechanism for the plasma treatment and facilitated transport of CO_(2)has been proposed on this basis.

Functionalized lipid nanoparticles modulate the blood-brain barrier and eliminate α-synuclein to repair dopamine neurons

The challenge in the clinical treatment of Parkinson's disease lies in the lack of disease-modifying therapies that can halt or slow down the progression. Peptide drugs, such as exenatide (Exe), with potential disease-modifying efficacy, have difficulty in crossing the blood-brain barrier (BBB) due to their large molecular weight. Herein, we fabricate multi-functionalized lipid nanoparticles (LNP) Lpc-BoSA/CSO with BBB targeting, permeability-increasing and responsive release functions. Borneol is chemically bonded with stearic acid and, as one of the components of Lpc-BoSA/CSO, is used to increase BBB permeability. Immunofluorescence results of brain tissue of 15-month-old C57BL/6 mice show that Lpc-BoSA/CSO disperses across the BBB into brain parenchyma, and the amount is 4.21 times greater than that of conventional LNP. Motor symptoms of mice in Lpc-BoSA/CSO-Exe group are significantly improved, and the content of dopamine is 1.85 times (substantia nigra compacta) and 1.49 times (striatum) that of PD mice. α-Synuclein expression and Lewy bodies deposition are reduced to 51.85% and 44.72% of PD mice, respectively. Immunohistochemical mechanism studies show AKT expression in Lpc-BoSA/CSO-Exe is 4.23 times that of PD mice and GSK-3β expression is reduced to 18.41%. Lpc-BoSA/CSO-Exe could reduce the production of α-synuclein and Lewy bodies through AKT/GSK-3β pathway, and effectively prevent the progressive deterioration of Parkinson's disease. In summary, Lpc-BoSA/CSO-Exe increases the entry of exenatide into brain and promotes its clinical application for Parkinson's disease therapy.

Fuel of the Future

Lawmakers call for stepping up hydrogen power production to facilitate China’s clean and low-carbon energy transformation and create a new engine of growth.

Effects of primary PCI and facilitated PCI on myocardial viability and ventricular systolic synchrony in acute myocardial infarction patients

Objective To evaluate short time effects of primary percutaneous coronary intervention (pPCI) and rtPA thrombolysis+PCI (rtPA+PCI) on myocardial viability and ventricular systolic synchrony in AMI patients.Methods Eighty seven patients with first AMI were divided into two groups: group A ( n =42), pPCI group, the patients underwent PCI within 6h after onset of AMI; group B ( n =45), rtPA+PCI group, the patients underwent PCI after thrombolysis within 6h after onset of AMI; Myocardial viability was measured by 99m Tc MIBI SPECT. While, the parameters of cardiac function LVEF and ventricular systolic synchrony LVPS were measured by 99m Tc gated cardiac blood pool image on the first and the fourth weekend. Results (1) The peak CK MB was significantly lower in group A than that in group B( P <0.01 ). (2) Myocardial infarction area (MIA) was decreased and radioactivity counts in MIA was significantly increased in group A and B on the 4th weekend compared with that on the first weekend ( P <0.01 ), but there were no significant difference between group A and group B. (3) LVEF, LVPS were no significant difference between group A and group B.Conclusions (1)pPCI in acute myocardial infartion can limit infarct area, maintain ventricular systolic synchrony and improve ventricular function; (2) but, in those hospitals that there were no any condition for PCI, they should transfer the patients to central hospital for PCI after thrombolysis at the first time. It is beneficial to improve myocardial viability and ventricular systolic synchrony of AMI patients in short time.

Therapeutic efficacy of acupuncture combined with neuromuscular joint facilitation in treatment of hemiplegic shoulder pain

BACKGROUND Stroke is a type of cerebrovascular disease with high prevalence,mortality,and onset of disability.As a neurodevelopmental therapy,neuromuscular joint facilitation(NJF)is widely used in the treatment of orthopedic and neurological disorders in the clinical practice.It is mainly used for central nervous system diseases or orthopedic diseases,movement disorders,and pain rehabilitation.According to related studies,NJF can also be used as a rehabilitation treatment in patients with hemiplegic shoulder pain(HSP).AIM To investigate the clinical efficacy of acupuncture combined with NJF in patients with HSP.METHODS Forty patients with HSP were randomly divided into a treatment group and a control group.The treatment group was treated with acupuncture combined with NJF and the control group was treated with acupuncture alone.All patients were assessed by using the visual analogue scale(VAS),Fugl-Meyer assessment(FMA),Barthel index(BI),and passive range of motion(PROM)before and after the training.All the clinical data were analyzed using SPSS 20.0 statistical software.RESULTS There was no statistical difference in the general characteristics between the two groups.In the terms of duration of treatment,age,and pre-treatment indicators,the two groups were comparable(P>0.05).After the treatment,VAS,PROM,BI,and FMA scores were significantly improved in the two groups of patients(P<0.05).The VAS,PROM and FMA scores were significantly higher in the treatment group than in the control group(P<0.05).However,there was no significant difference in BI scores between the two groups(P>0.05).CONCLUSION Both acupuncture alone and acupuncture combined with NJF in the treatment of HSP are effective,and can improve the clinical symptoms of patients.Acupuncture combined with NJF can improve the upper limb motor function,relieve pain,and increase joint mobility in patients with HSP.The combination therapy is better than acupuncture alone.However,there is no significant difference in improving the score of patients’self-care ability.

PVA/PVP blend polymer matrix for hosting carriers in facilitated transport membranes: Synergistic enhancement of CO2 separation performance

CO2 separation performance in facilitated transport membranes has been reported depended not only on the CO2 carrier properties but also to a great extent on the polymeric matrix regarding the capacity of retaining water and carriers as well as the processability for coating defect-free ultra-thin films. In this study, the blends of hydrophilic polymers polyvinyl pyrrolidone(PVP) and polyvinyl alcohol(PVA) were studied to find an optimal polymer matrix to host carriers in facilitated transport membranes for enhanced CO2 separation. It is found out that the optimized blend is 50/50 PVA/PVP by weight, which shows a significant increase in the water uptake(from 63 to 84%) at equilibrium state compared to the neat PVA. Polyethyleneimine(PEI) was employed to provide sample carriers to evaluate the synergistic effect of PVA and PVP on the CO2 separation performance. A thin film composite(TFC) membrane of the optimized blend(50/50 PVA/PVP with 50 wt% PEI) was fabricated on polysulfone(PSf) porous support. The fabrication of the TFC membranes is simple and low cost, and CO2 permeance of the optimized blend membrane is nearly doubled with the CO2/N2 selectivity remained unchanged, showing great potential for industrial applications of the resulted membranes.

Polyvinylamine-Based Facilitated Transport Membranes for Post-Combustion CO_(2) Capture:Challenges and Perspectives from Materials to Processes

Carbon dioxide(CO_(2))capture by gas-separation membranes has become increasingly attractive due to its high energy efficiency,relatively low cost,and environmental impact.Polyvinylamine(PVAm)-based facilitated transport(FT)membranes were developed in the last decade for CO_(2) capture.This work discusses the challenges of applying PVAm-based FT membranes from materials to processes for postcombustion CO_(2) capture in power plants and cement factories.Experiences learned from a pilot demonstration system can be used to guide the design of other membranes for CO_(2) capture.The importance of module and process design is emphasized in the achievement of a high-performance membrane system.Moreover,the results from process simulation and cost estimation indicate that a three-stage membrane system is feasible for achieving a high CO_(2) purity of 95 vol%.The specific CO_(2) capture cost was found to significantly depend on the required CO_(2) capture ratio,and a moderate CO_(2) capture ratio of 50%presented a cost of 63.7USD per tonne CO_(2) captured.Thus,FT membrane systems were found to be more competitive for partial CO_(2) capture.

GAS BUBBLE-FACILITATED TRANSPORT OF METALS IN LITHOSPHERE

１ＩＮＴＲＯＤＵＣＴＩＯＮＳｔｕｄｉｅｓｏｎｄｉｓｔａｎｔｍｉｇｒａｔｉｏｎｏｆｅｌｅｍｅｎｔｓｆｒｏｍｔｈｅｄｅｐｔｈｏｆｔｈｅｅａｒｔｈｈａｖｅｉｎｃｒｅａｓｅｄｓｉｎｃｅ１９８０．Ｏｎｅｏｆｔｈｅｓｅｓｔｕｄｉｅｓｉｓｆｏｃｕｓｅｄｏｎｔｈｅｔ...

Elevated NKCC1 transporter expression facilitates early post-traumatic brain injury seizures

As a leading cause for morbidity and mortality in young adults,traumatic brain injury（TBI）,along with the poorly understood TBI-related seizures inducing their predispositions,pose a major health and socioeconomic problem in the world（Huang,2013）.

Response of root traits of Reaumuria soongorica and Salsola passerina to facilitation

C3 plant Reaumuria soongorica and C4 plant Salsola passerina are super xerophytes and coexist in a mixed community in either isolated or associated growth, and interspecific facilitation occurs in associated growth. In the present study, the root traits including root distribution, root length（RL）, root surface area（RSA）, root weight（RW） and specific root length（SRL） of both species in two growth forms were investigated to clarify their response to facilitation in associated growth. Six isolated plants of each species, as well as six associated plants similar in size and development were selected during the plant growing season, and their roots were excavated at 0–10, 10–20, 20–30, 30–40 and 40–50 cm soil depths at the end of the growing season. All the roots of each plant were separated into the two categories of fine roots（2 mm diameter） and coarse roots（≥2 mm diameter）. Root traits such as RL and RSA in the fine and coarse roots were obtained by the root analyzing system WinRHIZO. Most of the coarse roots in R. soongorica and S. passerina were distributed in the top 10 cm of the soil in both growth forms, whereas the fine roots of the two plant species were found mainly in the 10–20 and 20–30 cm soil depths in isolated growth, respectively. However, the fine roots of both species were mostly overlapped in 10–20 cm soil depth in associated growth. The root/canopy ratios of both species reduced, whereas the ratios of their fine roots to coarse roots in RL increased, and both species had an increased SRL in the fine roots in associated growth. In addition, there was the increase in RL of fine roots and content of root N for S. passerina in associated growth. Taken together, the root growth of S. passerina was facilitated for water and nutrient exploration under the interaction of the overlapped roots in both species in associated growth, and higher SRL allowed both species to more effectively adapt to the infertile soil in the desert ecosystem.