An Assessment of Heavy-Metal Contamination in Soils within Auto-Mechanic Workshops Using Enrichment and Contamination Factors with Geoaccumulation Indexes

Soil characterization and heavy metals in different layers (0 - 15 cm;15 - 30 cm and 30 - 45 cm depth) of automobile mechanic waste dumps were studied. The soils showed remarkably high levels of all the metals above background concentrations with most (Ni, Cu, Fe, Cr and Cd) decreasing with soil depth. The distribution pattern were in the following order Fe > Cu > Zn > Pb > Cr > Ni > Cd. Across all the sampling locations and profiles, Fe and Cd showed the highest (476.4 μg·g-1) and least (37.5 μg·g-1) mean concentrations respectively. Pollution load index (PLI) and index of geoaccumulation (Igeo) revealed overall high and moderate contamination respectively but the enrichment factors (EFs) for Pb Ni and Cd are severe. The inter-element relationship revealed the identical source of elements in the soils of the studied area. The accuracy of the results has been cheeked using the standard reference material;SRM (PACS-2). The mechanic waste dumps represent potential sources of heavy metal pollution to environment. The elevated levels of heavy metals in these soil profiles constitute a serious threat to both surface and groundwater.

The stability safety factor calibration based on the reliability index

When the bridge structure stability safety factor of the first type is 4, the research that whether the structure reliability index will reach target reliability index under the more-likely-to-happen collapse situation of the second type is necessary. The stability calculations of the first and the second type are made respectively for single layer and single span rigid frame bridge. Based on the critical load obtained from the stability calculation of the first type, the stability safety factor of the first type is taken as 4, and the first order reliability method is used to program and calculate the reliability index. Then, the load effect under the stability reliability index cal- culation of the first type and the critical load of the second type are employed to calculate the reliability index of the second type. The evaluation of structure stability safety factor is discussed according to reliability index. Based on the discussion above, parameter analysis of the stable critical loads of two types is made, and the in- fluence of critical load change on reliability index is researched. The result shows that stability analysis should identify collapse state; when the stability safety factor of the first type is 4, but the structure has the collapse of the second type, the reliability index cannot be ensured to reach the target reliability index under certain condi- tions.

Estimation of Global Solar Radiation Using Clearness Index and Cloud Transmittance Factor at Trans-Himalayan Region in Nepal

This paper presents the global solar radiation (GSR) and cloud transmittance factor (cf) measured at the horizontal surface over a period of one year from 2009 to 2010 using CMP6 Pyranometer and NILUUV Irradiance Meter at Lukla (Latitude 26.69oN,Longitude 86.73?E and Altitude 2850 m) in the foothills of the Mt Everest (8850 m high). Monthly and seasonal variations of global solar radiation as well as correlation between clearness index and cloud transmittance factor at Lukla are presented. The annual average daily global solar radiation is about 3.83 kWh/sq·m/day which is sufficient to promote solar active and passive energy technology at high mountain terrain where there is no other viable alternative sources of energy. The maximum and minimum global solar radiation of 5.33 and 2.08 kWh/sq·m/day is recorded in April and September 2010 respectively. The seasonal variation of solar energy is about 2.87 kWh/sq·m/day and 4.83 kWh/sq·m/day in summer and spring respectively which is not in line with the general trend. The coefficient of determination (R2) between cloud transmittance factor (cf) and clearness factor (K) is found to be 0.97. This novel result can be utilized to estimate the global solar radiation at the horizontal surface where K and cf are available.

Risk factors and ankle brachial indexes in cerebral infarction combined with peripheral arterial disease

BACKGROUND: Ankle brachial index (ABI) is widely involved in researches and clinical application of peripheral vascular injury of patients with diabetes mellitus (DM); however, the application in cerebral infarction (CI) is rare. OBJECTIVE: To investigate the possible risk factor of cerebral infarction plus peripheral arterial disease (PAD), compare metabolic characteristics of patients who having CI plus PAD or only having CI, and understand the significance of ABI on screening and diagnosing CI plus PAD of lower limb. DESIGN: Contrast observation based on CI patients. SETTING: Department of Neurology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region. PARTICIPANTS: A total of 124 CI patients were selected from Department of Neurology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region from July 2005 to April 2006, including 72 males and 52 females aged from 45 to 88 years. All patients met the diagnostic criteria of cerebrovascular disease established by National Academic Conference of Cerebrovascular Diseases in 1995 and determined as cerebral infarction with MRI or CT examination. All patients provided informed consent. There were 46 cases (37.2%) with CI plus PAD and 78 cases (62.8%) only with CI. METHODS: Blood pressure of bilateral ankles and upper extremities was measured at plain clinostatism with DINAMAP blood pressure monitor (GE Company). The ratio between average systolic pressure of lateral ankle and average systolic pressure of both upper extremities was regarded as ABI. The normal ABI was equal to or more than 0.9. If ABI < 0.9 occurred at one side, patients were diagnosed as PAD. On the second morning after hospitalization, blood was collected to measure fasting blood glucose (FBG), 2-hour postprandial blood glucose (PBG2h), glycosylated hemoglobin (HbA1c), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Among them, blood glucose, lipid and other biochemical markers were measured with enzyme chemistry assay and HbA1c was measured with HbA1c meter based on high liquid phase. Measurement data and enumeration data were compared with t test and Chi-square test, and multiple factors were dealt with Logistic regression analysis and multivariate linear regression analysis. MAIN OUTCOME MEASURES: Results of correlation between ABI and metabolic markers with multivariate linear regression analysis; risk factors of CI plus PAD with Logistic regression analysis; comparisons of metabolic markers between PAD and non-PAD patients. RESULTS: All 124 patients with acute CI were involved in the final analysis. ① Comparisons of metabolic markers: Levels of serum LDL-C and uric acid (UA) were higher of PAD patients than those of non-PAD patients (t =2.051 9, 3.339 1, P < 0.05); however, there were no significant differences among other metabolic markers (P > 0.05). ② Results of multivariate linear regression analysis: PBG2h, LDL-C and UA were obvious correlation with ABI of posterior tibial artery of lower limb and dorsal pedis artery (partial regression coefficient = -0.231 to -1.010, P < 0.05). ③ Risk factors of CI plus PAD with Logistic regression analysis: Age, smoking history, sum of CI focus (≥3) and LDL-C were independent risk factor of CI plus PAD (OR =1.524-5.422, P < 0.05-0.01). CONCLUSION: ① Levels of serum LDL-C and UA of patients with CI plus PAD are high. ② ABI of lower limbs is correlation with PBG2h, LDL-C and UA. In addition, measuring ABI is beneficial for early diagnosing PAD of lower limbs of patients who have poorly controlled blood glucose, abnormal lipid and poor renal function. ③ Age, LDL-C and sum of CI focus (≥3) are independent risk factors of CI plus PAD. It is of significance for screening non-PAD patients to evaluate risk degrees and prognosis and select therapeutic methods based on ABI measurement.

BD-77雾化吸入给药对肺炎支原体感染小鼠的治疗作用

目的评价BD-77雾化吸入给药对肺炎支原体肺炎小鼠模型的治疗作用。方法Balb/c小鼠按照体质量随机分为正常对照组、模型对照组、阿奇霉素对照组(42 mg·kg^(-1)·d^(-1))、BD-77高剂量组(75 mg·mL^(-1),雾化15 min)、BD-77低剂量组(37.5 mg·mL^(-1),雾化15 min)。以肺炎支原体滴鼻感染建立小鼠支原体肺炎模型,雾化给药4 d后,通过小鼠体重及肺重计算肺指数和肺指数抑制率,酶联免疫吸附试验(ELISA)检测肺组织中白介素-6(IL-6)、白介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)含量及血清中C反应蛋白(CRP)水平,苏木精-伊红(HE)染色评估小鼠肺组织病理学变化,全面评价BD-77对小鼠支原体肺炎的治疗作用。结果BD-772个剂量组雾化吸入给药15 min均可显著降低小鼠肺指数,减轻肺部炎症病变,降低肺组织中IL-6、IL-1β、TNF-α含量及血清CRP水平。结论BD-77雾化吸入可治疗支原体感染小鼠肺炎,本研究为BD-77开发作为防治肺炎支原体肺炎的药物提供了实验室数据支持。

Assessing Total Factor Productivity for Soybean Production in China Based on DEA-Malmquist Index: 2005-2017

The low and slowly increasing soybean yield restricts the development of soybean production. Accurate measures of total factor productivity (TFP) for soybean production can be helpful in identifying conditions, institutions or policies that promote soybean production development in China. In this paper, TFP growth for soybean production was estimated for a panel data of 10 major soybean producing provinces from 2005 to 2017. Results reveal that TFP grew at an average rate of 1.3% over the whole period, with technical progress contributing 2.3% and efficiency change providing the other -1.0%. The change of TFP for soybean production over that time, whether increase or decline, was mainly derived by technical change except in three years (2005-2007). Positive TFP growth in the provinces of Liaoning and Inner Mongolia, and negative TFP growth in Hebei and Anhui were mainly driven by efficiency change, specifically scale efficiency change except pure technical efficiency in Liaoning.

老年急性脑出血患者并发低钾血症的相关危险因素及风险预测模型构建

目的 探讨老年急性脑出血患者并发低钾血症的相关危险因素,并且基于logistic回归构建风险预测模型。方法 选取2022年6月至2024年5月佛山市中医院诊治的老年急性脑出血患者190例,根据有无并发低钾血症分为低钾血症组(血钾<3.5 mmol/L)51例和正常组(血钾3.5~5.5 mmol/L)139例。采用logistic回归分析影响急性脑出血患者并发低钾血症的危险因素,并根据危险因素构建综合指数模型;ROC曲线分析综合指数预测急性脑出血患者并发低钾血症危险因素的诊断价值。结果 低钾血症组女性、入院时美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale, NIHSS)评分、入院时尿素、入院时血清肌酐、肾小球滤过率≤60 ml/min、呋塞米剂量>20 mg/d比例高于正常组(P<0.01)。单因素logistic回归分析显示,女性、入院时NIHSS评分、入院时尿素、入院时血清肌酐、肾小球滤过率≤60 ml/min、呋塞米剂量>20 mg/d为老年急性脑出血患者并发低钾血症的危险因素(P<0.05,P<0.01);多因素logistic回归分析显示,女性、入院时NIHSS评分、肾小球滤过率≤60 ml/min、呋塞米剂量>20 mg/d为老年急性脑出血患者并发低钾血症的危险因素(OR=6.393,95%CI:2.138~19.112,P=0.001;OR=3.123,95%CI:2.161~4.513,P=0.000;OR=3.327,95%CI:1.137~9.736,P=0.028;OR=3.111,95%CI:1.083~8.933,P=0.035)。ROC曲线分析显示,女性、入院时NIHSS评分、肾小球滤过率≤60 ml/min、呋塞米剂量>20 mg/d及综合指数预测急性脑出血患者并发低钾血症的曲线下面积分别为0.621、0.897、0.601、0.613、0.857,敏感性分别为52.90%、76.50%、49.00%、54.90%、72.50%,特异性分别为71.20%、88.50%、71.20%、67.60%、87.80%。结论 女性、入院时NIHSS评分、肾小球滤过率≤60 ml/min、呋塞米剂量>20 mg/d可能会对急性脑出血患者并发低钾血症产生影响,并依据这些危险因素构建综合指数模型对预测急性脑出血患者并发低钾血症具有较高的效能。

恩施州乡村旅游地农户返贫风险评估及其影响因素研究

有效预防返贫风险是后脱贫时代脱贫攻坚和乡村振兴战略有效衔接的关键.该研究将风险的概率纳入返贫风险评估体系,从发生概率和破坏程度两方面综合评估其返贫风险,系统反映返贫风险的可能性和破坏性,进而探究其影响因素.研究发现:1)农户各维度的返贫风险水平从高到低依次为个体风险、家庭风险、社会风险和自然风险,农户受家庭风险和个体风险影响较大,存在明显的内生性、个体化特征.2)依据风险的发生概率和破坏程度,返贫风险可分为“高概率-高破坏”型、“高概率-低破坏”型和“低概率-低破坏”型3种类型,其中,“高概率-高破坏”型风险包括非农就业能力和教育负担,返贫风险指数最高,对农户返贫的威胁最大.3)抚养人数和户主的文化程度等家庭特征是影响返贫风险的主要因素,乡村旅游扶贫开发模式不同导致农户的返贫风险存在显著差异.在返贫防治实践中,应因户施策,重点防治内生性返贫,同时要根据返贫风险发生概率及破坏程度的差异,制定合理的返贫风险预警机制及防治措施.

多馈入直流换相失败与同步电网交互影响机理研究评述

换相失败场景下交直流交互影响机理是多馈入直流系统安全稳定控制决策前提。从直流换相失败分类及机理、换相失败影响因素、换相失败评价指标及风险评估4个方面梳理了换相失败与同步电网交互影响机理研究现状,并从直-交、交-直两个角度分析了交直流电网的交互影响,最后介绍了基于受扰轨迹知识提取的交直流系统量化分析方法及应用现状,实例分析单直流换相安全评估方法推广至多直流连续换相失败的可行性,指出基于关断角受扰轨迹提取的量化分析方法能实现多馈入直流换相安全量化评估和换相安全性与系统稳定性的交互影响分析,后续应该理论分析多馈入直流换相失败场景下电压和频率跌落可接受性量化评估的适应性,在多维量化指标空间内,深入探讨同步电网多时间尺度复杂动态响应对多馈入直流换相安全的影响规律,揭示多馈入直流换相失败与同步电网动态响应相互作用机理。

生态旅游赋能矿山修复开发适宜性评价及影响因素

【目的】发展生态旅游赋能以绿色矿山为代表的矿山土地综合修复利用受到广泛关注,研究生态旅游赋能矿山修复开发适宜性评价体系与影响因素,为全国绿色矿山生态旅游高质量发展提供技术支撑。【方法】基于层次分析法(AHP)从科研价值、历史文化价值、休闲游憩价值、生态环境价值、矿区开发条件、城市开发环境6个维度构建了绿色矿山生态旅游评价指标体系,以湖南为案例地,运用因子分析法测算湖南绿色矿山生态旅游开发适宜性评价,采用多元线性回归方法分析了湖南绿色矿山生态旅游开发的影响因素。【结果】结果显示,湖南绿色矿山生态旅游开发评价指标综合评分最高为0.84,最低为0.38,开发评价指标综合评分差距较小。旅游资源丰富程度、生态环境质量、政策支持情况通过了1%水平的显著性检验,基础设施、相关者的参与度和友善度、交通便利性通过了5%水平的显著性检验,且与湖南绿色矿山生态旅游开发存在正相关关系,风险安全状况对湖南绿色矿山生态旅游开发影响不显著。【结论】湖南省生态旅游赋能矿山修复开发潜力大,为此,应加强政府的宏观规划管理,制定相应政策法规,引导和保障矿山生态旅游开发。加强科学技术与数字化水平,加大创新投入,充分利用矿山遗留资源和当地文化,在生态修复保护的基础上,提高矿山生态旅游价值,打造矿山生态旅游产品。

基于广义超椭球模型的结构非概率可靠性指标

非概率凸集合模型仅需获知结构不确定性的范围或界限来度量结构可靠性,因而适用于小样本不确定性结构工程问题.针对广义超椭球模型,对其非概率可靠性度量问题进行了研究.首先,提出了基于广义超椭球模型的简单非概率可靠性指标,定义为结构功能函数的均值与离差之比,并讨论了该可靠性指标的不一致性问题.其次,为克服上述不一致性问题,提出了一种比例因子非概率可靠性指标,定义为不确定域向外扩大或向内收缩时,失效面与不确定域接触的最小比例因子.最后,通过3个工程算例分析验证了所提非概率可靠性指标的有效性和可行性.

基于DEA-ESDA模型和Malmquist指数的我国卫生服务供给效率研究

[目的]分析我国卫生服务供给效率,为提高医疗卫生服务质量提供依据。[方法]基于我国2013-2021年31个省份卫生服务投入产出数据,运用DEA-BCC模型对数据进行静态分析;运用DEA-Malmquist方法进行动态分析;运用探索性空间数据分析(ESDA)研究空间分布特征。[结果]2013-2021年我国东部、中部地区卫生服务供给综合效率(VRS)值较高,东北地区、西部地区综合效率值较低;2021年综合效率均值为0.943,DEA非有效的省份有13个;全要素生产率下降主要由技术进步效率的下降导致;卫生服务供给效率具有显著空间负相关性,呈“低-高”“高-低”聚集。[结论]我国卫生服务供给效率普遍较低,不同地区间差距明显,卫生资源配置效率低,资源供给不均,存在技术“洼地”。各省需结合本地实际情况合理配置资源,充实人才队伍,鼓励技术创新,依托互联网信息技术,促进区域协同发展。

区域创新发展能力评价与空间差异测度

区域创新发展能力是区域经济在发展过程中获取竞争优势的重要影响因素,文章从区域创新发展规模、区域创新发展条件、区域创新发展活力、区域创新发展环境四个子系统筛选出20个可观测指标构建区域创新发展能力评价指标体系,应用面板数据熵权法对我国31个省份2014—2019年创新发展能力进行综合评价,利用泰尔指数和莫兰指数对创新发展能力空间差异特征进行分析,并为区域创新发展能力实现协同发展提供参考。

市场性因素介入之内幕交易罪违法所得的计算

内幕交易罪等证券类犯罪因涉及多方主体、复杂的违法链条、严重的危害后果以及隐蔽的犯罪手段,对市场交易秩序造成严重破坏,一直是监管部门严厉打击的重点。为实现刑法的有效规制并保障人权,科学准确地计算内幕交易罪的违法所得数额显得尤为重要。在实践中,市场性因素的介入会导致内幕交易罪中行为人所获得的收益或避免的损失数额增大。对于扩大的收益或者避免的损失数额,由于不符合没收违法所得制度的宗旨与内涵,因此不能计入行为人的违法所得数额。在具体计算方法上,法院可以综合选取相关市场指数或者个股组合作为参照,综合测算市场性因素所导致的股市波动权重,进而将其从违法所得的认定中排除。

婴儿体脂指数的影响因素分析

目的探究不同性别婴儿体脂指数(FMI)的影响因素。方法于2021年10月至2022年12月,在山东省开展婴儿体成分的横断面研究,对研究对象进行电子问卷调查和体成分测量获取研究数据,最终纳入9291份有效数据,应用多因素线性回归分析不同性别婴儿FMI的影响因素。结果不同性别婴儿月龄与FMI具有显著正相关。与适于胎龄儿相比,大于胎龄儿的FMI增加(β值分别为0.086、0.078,P<0.001),小于胎龄儿的FMI降低(β值分别为-0.088、-0.072,P<0.001)。与6月龄以后添加辅食相比,4~6月龄添加辅食男女婴儿FMI均增加,差异均具有统计学意义(β值分别为0.099、0.053,P<0.001)。与父母亲体重正常相比、父母亲肥胖与婴儿FMI的增加显著相关(β值分别为0.058、0.070和0.054、0.058,P<0.001),母亲体重过低与婴儿FMI降低显著相关(β值分别为-0.039、-0.046,P=0.005、0.002)。妊娠期糖尿病与婴儿FMI降低显著相关(β值分别为-0.039、-0.046,P=0.005、0.002),妊娠期高血压与男婴FMI升高显著相关(β=0.028,P=0.038)。纯配方奶喂养对女婴FMI存在显著正向影响(β=0.029,P=0.046)。孕期增重不足对女婴FMI存在显著负向影响(β=-0.033,P=0.032)。结论影响婴儿身体成分的因素有胎龄别体重、喂养方式、辅食添加时间、母亲孕期增重及孕期疾病等,应在生命早期采取干预措施进行控制,预防子代代谢性疾病的发生。

碳排放约束下我国地级及以上城市物流效率研究

绿色发展是物流业健康发展的一个关键因素。借助非期望产出超效率SBM模型和Global Malmquist-Luenberger指数模型,分别计算在碳排放约束下2009—2020年中国339个地级及以上城市的物流效率和物流全要素生产率,再运用空间马尔科夫链揭示物流效率类型转移的空间溢出效应,最后通过泰尔系数和变异系数研究物流业全要素生产率指数在城市间与省际的区域差异。研究发现:(1)我国碳排放约束下物流效率呈上升态势,在空间上呈现出东部地区高、中西部地区低的特征,在逐渐通车的铁路干线与公路干线周围的城市物流效率提升明显。(2)同一时间段内,不同物流效率类型的城市对其邻近城市的物流效率转移有明显带动或抑制影响。(3)物流业GML指数值大于等于1的城市在全国各个地区分布大致均匀,物流全要素生产率受技术进步指数的影响较大。(4)省际物流业全要素生产率的差异明显高于城市间物流业全要素生产率的差异。基于结果分析提出在碳排放约束下提升物流效率和全要素生产率的对策建议。

西昌市中学生高血压发病情况及其危险因素分析

目的分析西昌市中学生高血压发病情况及相关危险因素,指导西昌市中学生高血压的防治。方法采用整群随机抽样的方法,从西昌市及周边乡镇学校收集学生数约13999例,全部进行血压测量,明确高血压的诊断及高血压相关危险因素,包括性别、年龄、民族、体重指数等,分析高血压发病情况及相关危险因素。结果本人群中共有高血压患者31人,高血压患病率0.221%。其中男性高血压患病率(0.448%)高于女性高血压患病率(0.027%),平均收缩压及舒张压均高于女性(P<0.01)。少数民族中学生平均舒张压水平低于汉族中学生平均舒张压水平,差异有统计学意义(P<0.01)。不同年龄段各组间的高血压患病率及血压均值比较,差异有统计学意义,19~22岁组高血压患病率最高,平均血压最高(P<0.01)。不同体重指数各组间的高血压患病率及血压均值比较,差异有统计学意义,肥胖高血压患病率最高,平均收缩压及舒张压最高(P<0.01)。结论性别、年龄、体重指数是西昌市中学生高血压发病独立危险因素,其中性别是最显著影响因素。

枸橼酸咖啡因辅助PS治疗新生儿呼吸窘迫综合征对血清炎症因子及血气分析的影响分析

目的 分析枸橼酸咖啡因辅助肺表面活性物质(Pulmonary Surfactant,PS)治疗新生儿呼吸窘迫综合征(Neonatal Respiratory Distress Syndrome,NRDS)的临床疗效及对患儿血清炎症因子、肺功能的影响。方法 单纯随机选择2020年1月—2023年1月南通大学附属妇幼保健院儿科收治的80例NRDS患儿为研究对象,按不同治疗方法分为两组,每组40例。对照组采用PS治疗,观察组联合枸橼酸咖啡因辅助治疗,两组均治疗2周。比较两组临床疗效、血清炎性因子、血气指标、治疗效果及并发症发生情况。结果 观察组临床疗效(95.00%)高于对照组,差异有统计学意义(χ^(2)=5.165,P=0.023)。治疗后,观察组C反应蛋白、降钙素原、白细胞计数低于对照组,差异有统计学意义(P均<0.05)。治疗后,观察组pH、动脉血氧分压、氧合指数高于对照组,动脉血二氧化碳分压低于对照组,差异有统计学意义(P均<0.05)。观察组呼吸机使用时间、用氧时间、住院时间均短于对照组,差异有统计学意义(P均<0.05)。观察组呼吸暂停次数少于对照组,差异有统计学意义(P<0.05)。两组并发症总发生率比较,差异无统计学意义(P>0.05)。结论 对NRDS患儿使用枸橼酸咖啡因辅助PS治疗可有效改善患儿血气指标,减轻炎症反应,提高治疗有效率,安全可靠。

阿莫西林克拉维酸钾四联疗法对幽门螺杆菌感染患者免疫指标及炎症因子的影响

目的观察阿莫西林克拉维酸钾四联疗法对幽门螺杆菌(Hp)感染患者免疫指标及炎症因子的影响。方法选取2023年1月至2024年1月石河子大学第一附属医院消化科收治的82例Hp感染初诊患者作为研究对象,采用随机数字表法分为对照组和观察组,各41例。对照组采用阿莫西林胶囊+胶体果胶铋胶囊+克林霉素分散片+艾司奥美拉唑镁肠溶片四联疗法治疗,观察组采用阿莫西林克拉维酸钾片+胶体果胶铋胶囊+克林霉素分散片+艾司奥美拉唑镁肠溶片四联疗法治疗。比较两组患者Hp根除率,治疗前后免疫指标(CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+))以及炎症因子[白细胞介素-6(IL-6)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)]水平。结果观察组患者Hp根除率明显高于对照组[95.12%(39/41)比75.61%(31/41)](χ^(2)=6.248,P=0.012)。治疗后,观察组患者CD4^(+)、CD4^(+)/CD8^(+)比值明显高于对照组[(48.3±5.2)%比(42.1±5.5)%、1.76±0.43比1.33±0.53](P<0.01),CD8^(+)明显低于对照组[(22.1±3.2)%比(26.8±3.6)%](P<0.01)。治疗后,观察组患者IL-6、CRP、TNF-α水平均明显低于对照组[(11.4±2.1)mg/L比(15.1±2.8)mg/L、(6.8±1.6)ng/L比(10.4±1.9)ng/L、(16.8±3.2)ng/L比(22.4±3.0)ng/L](P<0.01)。结论针对Hp感染初诊患者,阿莫西林克拉维酸钾四联疗法治疗的Hp根除率明显高于阿莫西林四联疗法,且患者免疫功能改善显著,炎症因子水平控制理想。

温肺扶阳祛痰方治疗慢性阻塞性肺疾病稳定期的疗效

目的探讨温肺扶阳祛痰方治疗慢性阻塞性肺疾病(COPD)稳定期疗效。方法选取COPD稳定期患者120例,随机分为两组。对照组应用噻托溴铵吸入粉雾剂^(+)茶碱缓释片,研究组在此基础上应用温肺扶阳祛痰方,对两组的肺功能、免疫、炎症因子指标以及生活质量进行评估,确定其应用价值。结果和对照组比较,研究组治疗后用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、第1秒用力呼气容积/用力肺活量(FEV1/FVC)、6 min步行距离(6MWD)均增大(P<0.05),CAT评分降低(P<0.05)。研究组治疗后C反应蛋白(CRP)、白细胞计数(WBC)、中性粒细胞计数(NEUT)水平均低于对照组(P<0.05)。研究组治疗后CD4^(+)、CD8^(+)T细胞比例、IgA、IgG水平优于对照组(P<0.05)。结论COPD稳定期患者在常规西药治疗基础上应用温肺扶阳祛痰方治疗效果更佳,可以有效降低机体中的炎症因子水平,提高患者肺功能和免疫功能,值得推广应用。