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Nerve guiding regeneration and controlled release of growth factor
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《Chinese Journal of Biomedical Engineering(English Edition)》 2001年第2期50-52,共3页
关键词 PDLLA Nerve guiding regeneration and controlled release of growth factor FGF
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The Growth of China’s Private Sector: A Case Study of Zhejiang Province 被引量:3
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作者 Zhikai Wang 《China & World Economy》 SCIE 2006年第3期109-120,共12页
Private capital is one of the main driving forces in China's initiatives towards stimulating the market economy. The development of private economy in China has always been based on integrating industrial and corp... Private capital is one of the main driving forces in China's initiatives towards stimulating the market economy. The development of private economy in China has always been based on integrating industrial and corporate structures with product composition and market structures. This paper explores the development of the private economy and how it integrates different industries with specific markets by analyzing the leading private sector in Zhejiang province. It also examines the trends of industrial cluster, the formation of the agglomerative economy and their effects on private economy development. Finally, the paper explains why Zhejiang people have profited much from the Wenzhou model and discusses some existing problems and future possibilities for development of the Wenzhou model. 展开更多
关键词 industrial growth integration of growth factors market development private economy
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Gelatin-based hydrogel functionalized with taurinemoieties for in vivo skin tissue regeneration 被引量:2
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作者 Farnaz Rahimi Nima Ahmadkhani +5 位作者 Aida Goodarzi Fariba Noori Sajad Hassanzadeh Sepideh Saghati Mehdi Khanmohammadi Arash Goodarzi 《Bio-Design and Manufacturing》 SCIE EI CAS CSCD 2023年第3期284-297,共14页
Functionalized hydrogels stimulate the migration and morphogenesis of endothelial cells(ECs)and are useful substrates for wound healing.The present study investigates the feasibility of covalent conjugation of taurine... Functionalized hydrogels stimulate the migration and morphogenesis of endothelial cells(ECs)and are useful substrates for wound healing.The present study investigates the feasibility of covalent conjugation of taurine(Tau)on a gelatin-based hydrogel.This hydrogel is expected to maintain positive charged growth factors such as basic fibroblast growth factor(bFGF)and vascular endothelial growth factors(VEGFs)near ECs within the hydrogel microenvironment.The gelatin was conjugated with hydroxyl phenol(Ph)and Tau moieties,and in following that Ph residues were crosslinked through a horseradish peroxidase-catalyzed reaction.The migration characteristics of ECs were analyzed by scratch migration assay and microparticle-based cell migration assay.Cellular morphology and amounts of angiopoietin 1(Ang 1),bFGF,and VEGF proteins were evaluated for encapsulated cells.The potential of synthesized hydrogels in wound healing was assessed by the percentage of reduction from the original wound size and histopathological analyses of rat skin.The incorporated Tau molecules within the hydrogel remained stable through covalent bonds during incubation.During extended incubation,the gelatin-based hydrogel conjugated with Tau improved the migration distance and number of existing migrated ECs.Immobilized Tau within the gelatin-based hydrogel induced high motility of ECs,accompanied by robust cytoskeleton extension and a cell subpopulation that expressed CD44 and CD31 receptors as well as enhancement of Ang 1,bFGF,and VEGF.We found that injectable Gel-Ph-Tau effectively improves wound-healing parameters. 展开更多
关键词 Taurine conjugation Covalent crosslinking Immobilization of growth factors Gelatin-based hydrogel Endothelial cells
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