Evaluation of the famous classic formula Sanhua decoction based on network pharmacology and multi-component quantitative analysis

Background:Sanhua decoction has significant effects in the treatment of stroke.The study of the Sanhua decoction material benchmark was carried out to analyze the value transfer relationship between the Chinese herbal pieces and the substance benchmark.Methods:Network pharmacology was employed to investigate the potential active components and molecular mechanisms of Sanhua decoction in the treatment of stroke.15 batches of Sanhua decoction lyophilized powder were prepared using traditional formulas and subjected to high-performance liquid chromatography analysis to generate fingerprints of the Sanhua decoction substance benchmarks.Then,a multi-component quantitative analysis method was established,allowing for the simultaneous determination of ten components,to study the transfer of quantity values between pieces and substance benchmarks.Results:60 active ingredients were screened from Sanhua decoction by network pharmacology,of which gallic acid,magnolol honokiol,physcion,and aloe-emodin may have a greater effect than other active components.63 key targets and 134 pathways were predicted as the potential mechanism of Sanhua decoction in treating stroke.The fingerprint similarity of the Sanhua decoction substance benchmarks was found to be good among the 15 batches,confirming the 19 common peaks.The content of the 10 components was basically consistent.The components’transfer rates were within 30%of their respective means.Conclusions:This study provided a comprehensive and reliable strategy for the quality evaluation of Sanhua decoction substance benchmarks and held significant importance in improving its application value.

Clinical research report on traditional Chinese patent medicines and traditional Chinese classic famous prescriptions(2022)

Objective:The paper is to comprehensively summarize and analyze the basic situation and methodological quality of clinical randomized controlled trials(RCTs)of traditional Chinese patent medicines and traditional Chinese classic famous prescriptions published in 2022,to provide evidence and reasonable suggestions for the advancement of clinical research and the formulation of policies and guidelines.Methods:The Evidence Database System of clinical evidence-based evaluation of traditional Chinese medicine was searched,and data from China National Knowledge Infrastructure(CNKI),PubMed,and other databases were supplemented.The search duration was from January 1,2022,to December 31,2022.RCTs of traditional Chinese patent medicines and traditional Chinese classic famous prescriptions were included as the source of clinical evidence,and published information,sample size,intervention,control measures,treatment course,methodological quality,and key link report were analyzed and evaluated.Results:A total of 1,464 RCTs of traditional Chinese patent medicines were included,which comprised 667 types of traditional Chinese patent medicines;“traditional Chinese patent medicines+Western medicine vs.Western medicine”was the most widely used intervention and control setting,involving 417 RCTs(28.48%).A total of 245 RCTs of traditional Chinese classic famous prescriptions were included,comprising 55 types of traditional Chinese classic famous prescriptions.“Decoction+conventional treatment vs.conventional treatment”was the most widely used intervention and control setting,with 87 RCTs(35.51%).Published RCTs on traditional Chinese patent medicines and traditional Chinese classic famous prescriptions were limited by the study design and implementation.Most“allocation concealment”and“blinding of patients and personnel”were rated as medium to high risk.There are insufficient reports on key research links such as experimental registration and ethical approval.Conclusions:The number of RCTs on traditional Chinese patent medicines has decreased in 2022,but there has been a slight improvement in the research quality and impact.There are relatively few studies on traditional Chinese classic famous prescriptions.Measures must be taken to improve clinical trial design,implementation,and reporting.Methodological experts should be invited to provide professional technical guidance on the trial design.In the research implementation process,attention should be paid to quality control,particularly the standardization of the randomized execution.

Analysis of Mineral Elements in 13 Famous Tea Varieties in Sichuan Province

This study was to analyze the mineral elements in famous tea varieties in Sichuan Province. Eighteen mineral elements in the samples of 13 famous tea varieties in Sichuan Province were measured via related instruments. The results showed, of all the 18 measured samples, that the contents of K, P, S, Ca and Mg were relatively higher（ 〉1 500 mg/kg） in famous tea varieties in Sichuan Province, while those of Ba, Cr, V, Co and Se were relatively lower（ 〈 10 mg/kg） ; compared to common green tea, the famous tea varieties in Sichuan Province contained higher contents of K, Zn, P, Na, Ni, Cu, S, Se and Co（0.38% -115.65% higher than that in common green tea）, and lower contents of Mg, Mn, AI, Ca, V, Rb, Fe and Cr（7.20% -46.67% lower than that in common green tea）; of the 13 tested tea varieties, Hongyanyingchun, Yongchuanxiuya and Qingchengxueya were rich in mineral elements, while Yuchengyunwu and Yuqiancha lacked in mineral elements. The re- suits show that Hongyanyingchun, Yongchuanxiuya and Qingchengxueya are the elites in the famous tea varieties in Sichuan Province.

Research on Monitoring and Early-warning Standards of Ancient and Famous Trees Protection in the Humble Administrator's Garden

Based on the current situation and symptoms of the trees' growth in the Humble Administrator's Garden,this paper put forward corresponding monitoring and early-warning standards and technical measures of the ancient and famous trees protection in the Humble Administrator's Garden specifically.The aim of doing this is to establish a scientific basis for the protection of the ancient and famous trees in the Humble Administrator's Garden by setting up systematic fundamental data,dynamic protection standard grades and technique measures of protecting the trees.The main symptom of trees in the Humble Administrator's Garden is the erosion and decay of the tree trunks.Fifteen tree trunks need technical protection,which holds 65.22% of the total sum of trees in the Humble Administrator's Garden.Therefore,much more emphasis should be paid in strengthening technical protection procedures of monitoring and early warning of the tree trunks in the future protection of the ancient and famous trees in the garden.Besides,the rejuvenation technique of rooting zone and rooting system,tree pruning technique as well as tree supporting measures according to the specific condition and symptom of the trees should be concerned with in order to protect the ancient and famous trees in the Humble Administrator's Garden in a more scientific and effective way.

Current Situation of Ancient and Famous Trees and Ecological Landscapes in Classical Suzhou Gardens

Due to the regional characteristics and special environment of classical Suzhou gardens, ancient and famous trees in these gardens are not only organisms or natural resources, but also witnesses and recorders of history, so they have unique attributes and value of humanistic resources. On this basis, current situation of ancient and famous trees as well as ecological landscapes formed by these trees in classical Suzhou gardens were analyzed, connotations of these trees elaborated, and relevant regulations taken to identify the grade of these trees. Ancient and famous trees in 9 classical Chinese gardens were investigated, specifically, the Humble Administrator's Garden, the Lingering Garden, the Master-of-Nets Garden, the Mountain Villa with Embracing Beauty, the Pavilion of Surging Waves, the Lion Grove Garden, the Garden of Cultivation, the Couple's Retreat Garden and the Garden of Pleasure. Compared with statistics obtained in 2002, the quantity of ancient and famous trees in these 9 gardens reduced by 11. History and growth state of some trees were introduced, such as Pinus bungeana Zucc. ex Endl., Ginkgo biloba L., Sabina chinensis (Linn.) Ant., Buxus sinica (Rehd. et Wils.) Cheng, Cudrania tricuspidata (Carr.) Bur., and significance of the principle-"right tree for right land" for ancient trees aged 100 years or more was stressed. Moreover, it was stressed that garden protection should also devote more attention to researches on plants.

Research on the Value of Chinese Famous Mountainous Scenic Spots in the Perspective of Cultural Landscape

After summarizing relevant researches on famous mountainous scenic spots and the development of cultural landscapes in world cultural heritages, the paper has analyzed the value of famous mountainous scenic spots in China and considered that Chinese famous mountainous scenic spots are of rich natural science value and unique aesthetic value, have inherited traditional humane landscape aesthetic value, reflected the philosophical view of "the unity between heaven and human" and profound religious culture, and preserved rich cultural remains, corresponding with the definition and requirement of cultural landscape in world heritages.

Study on Present Situation of Ancient and Famous Trees in the Lingering Garden and Its Protective Measures

The field investigation of the present situation of ancient and famous tress in Lingering Garden was conducted, the results showed that there were 18 trees, belonging to 13 species, 12 genera and 10 families. The trees’ ages were between 100 years old and 330 years old; 14 trees (accounting for 77.78% of the total trees) required regular management, 2 trees (accounting for 11.11%) required bole antiseptic protection, 1 tree (accounting for 5.56% of the total plants) required protection for its trunk, and 1 tree (accounting for 5.56%) required bole antiseptic protection and rejuvenation. According to the survey results, the monitoring and early warning standard grades were divided, its reasons were analyzed, and finally, the relative protection and restoration countermeasures were put forward.

A Procedure for Trisecting an Acute Angle (Method 2)

This paper presents an alternate graphical procedure (Method 2), to that presented in earlier publications entitled, “A Procedure for Trisecting an Acute Angle” and “A Key to Solving the Angle Trisection Problem”. The procedure, when applied to the 30˚ and 60˚ angles that have been “proven” to be nottrisectable and the 45˚ benchmark angle that is known to be trisectable, in each case produced a construction having an identical angular relationship with Archimedes’ Construction, as in Section 2 on THEORY of this paper, where the required trisection angle was found to be one-third of its respective angle (i.e. DE’MA = 1/3 DE’CG). For example, the trisection angle for the 30˚, 45˚ and 60˚ angles were 10.00000˚, 15.00000˚, and 20.00000˚, respectively, and Section 5 on PROOF in this paper. Therefore, based on this identical angular relationship and the numerical results (i.e. to five decimal places), which represent the highest degree of accuracy and precision attainable by The Geometer’s Sketch Pad software, one can only conclude that not only the geometric requirements for arriving at an exact trisection of the 30˚ and 60˚ angle (which have been “proven” to be not-trisectable) have been met, but also, the construction is valid for any arbitrary acute angle, despite theoretical proofs to the contrary by Wantzel, Dudley, and others.

哈罗德·阿克顿与L.C.阿灵顿之他者戏剧审美言说在Famous Chinese Plays中的体现

Famous Chinese Plays是英国汉学家哈罗德·阿克顿与美国戏剧学家L.C.阿灵顿于20世纪30年代合作翻译编撰的中国京剧经典曲目汇集。这部译作不仅融汇了两位译者作为汉学家对中国传统戏剧艺术形式——京剧的关注,也倾注了两人对中国戏剧文化的个性化审美体认。这种基于西方文化而又寻求突破传统的异质审美取向的审美模子,在译介中撷取中国传统戏剧文化养分的同时,也不自觉地融入了西方文化浓厚的受体因子的评介体系,既旨在向西方介绍中国传统艺术形式,也兼顾了西方文化体系对中国传统审美理念的个性化维度思考。

Locating Famous Tea’s Picking Point Based on Shi-Tomasi Algorithm

To address the difficulty of locating the picking point of a tea sprout during the intelligent automatic picking of famous tea,this study proposes a method to obtain information on the picking point on the basis of the ShiTomasi algorithm.This method can rapidly identify a tea sprout’s picking point and obtain its coordinates.Images of tea sprouts in a tea garden were collected,and the G-B component of tea sprouts was segmented using the Otsu algorithm.The region of interest was set with the lowest point of its contour as the center.The characteristics of tea buds and branches in the area were extracted,and the Otsu algorithm was used for a second segmentation of tea sprout images.The tea buds were segmented using the improved Zhang algorithm.The branch feature binary image was used to refine the skeleton,and the Shi-Tomasi algorithm was used to detect the corners of the skeleton and calculate and mark the picking points of the shoots.Sixty sets of samples were tested.The test identified 1,042 effective shoots for tender buds,and 887 picking points were marked,with a success rate of 85.12%,thereby verifying the effectiveness of the method and providing a theoretical reference for the visual positioning of the automatic picking of famous tea.

Determination of Trace Elements in Famous Teas from Huangshan Area by ICP-AES

With an Iris Intrepid II XSP ICP full spectrum ICP emission spectrometer,trace elements including Se,Fe,Mn,Cd,Cr,Co,Ni,Cu,Pb and Zn in Huangshan teas were determined.The best analysis conditions were selected by experiments.The method is simple and rapid,and the precision and accuracy are all in line with the requirements.This method was used to analyze actual tea samples with satisfactory results.

Research on Landscape Planning and Design of Famous Historic and Cultural Sites as Outdoor Sightseeing and Relaxation Spaces——A Case Study of Taiqing Scenic Area in Mount Laoshan,Qingdao City

Design attributes of famous historic and cultural sites were analyzed,and problems in the present planning and design of these relics were proposed on the basis of fully studying characteristics of outdoor sightseeing and relaxation spaces in famous historic and cultural sites such as disordered route,lack of cultural context and overuse of design formalism.Taiqing Scenic Area in the Mount Laoshan was taken for example to explore design techniques of famous historic and cultural sites.It was stressed that history should be respected,cultural context continued;development properly designed,favorable ecological conditions created;tour routes reasonably designed,tourists' feelings valued;aesthetic principles should be followed,and beauty of scenery depends on moods of viewers.This study was to make the future design of famous historic and cultural sites practical.

On the Tone of Finality in Famous Successful Speeches

The public speech skill consists of cultural virtue,knowledge accumulation,psychological quality,logical thinking,thinking capacity and language expression.It is a kind of art that speakers achieve the success through their own sound.In dealing with various English speeches,Chinese students are always influenced by the Chinese way of speech delivery,adopting the style of it,especially its tone of finality.After collecting,arranging and learning relevant material,I attaches great importance to the tone of finality in famous English speeches.They show some rules and regulations,such as the return to the middle pitch,the unstable change of stress and the final rising and falling tone.This paper begins with a brief introduction to what the tone of finality is and three famous English speeches in different areas are provided as study cases with the PRAAT pictures and their relevant analysis.And then the comparison will be made among these three speeches from aspects of pitch,length and weight,in the hope of concluding similarities in the tone of finality of these three cases.

A STUDY ON THE ECOLOGICAL CLIMATES OF SOME FAMOUS TEA GROWING AREAS IN HIGH MOUNTAINOUS REGIONS OF CHINA

The tea tree [Camellia sinensis (L) Kuntze] is one of the world’s economic crops. It is an especially important crop for southern China. Environmental factors related to the tea yield and quality in some high mountain areas of China are identified in this paper. These factors are: geology, topography, climate, hydrology, soil and vegetation. Climatological factors are the most important. Using data collected from meteorological stations which are situated at the summit and the base of high mountains, this paper discusses ecological climatic problems in growing tea in China. The ecological climatic characteristics of the famous tea areas mainly included are as follows: more . amounts of clouds and fog, less percentage of sunshine, abundant rainfall and high relative humidity in the air, temperatures that rise and fall slowly, daily and annual temperature ranges that are smaller, more days that are suitable for tea growing and low wind speeds in the lee-sides and valleys of mountains. All of these

FAMOUS PRODUCTS

Model Z3040X 16/1 Radial Drilling Machine The Model Z3040X16/1 radial drilling machine made by the Shenyang Machine Tool Holdings Co. Ltd. won China state gold medals for quality in 1980. 1984 and 1989. It has a wide scope of changes on rotating and feeding speeds. It can be controlled for safe and accurate work by mechanism or hand. Its position movement of the spindle has a very small error rate. Its speed control mechanism is equipped on the spindle box for easy control. The pre-selection of hydrolic speed and feed is quick, accurate and flexible.

HUANG CUNSHAO——A FAMOUS EXPERT IN MINING

Huang Cunshao, late professor of the Department of Resources Exploitation of Central South University of Technology., graduated from the Mining and Metallurgical Engineering Department of

A Brief Discussion on the Safety of Famous Region Herb

With the vigorous development of the Chinese herbal medicine market in China,the production of high-quality authentic medicinal materials must not only ensure its unique authentic properties,but also ensure its quality and safety.This article elaborates the challenges faced by the authentic Chinese medicinal materials and gives suggestions to improve the quality system of Chinese medicinal materials.

Lianyungang's Famous Enterprises and Products

Jiangsu Suntory Food Co. Ltd.The company was established by jointinvestment from the China International TrustInvestment Corporation, the Jiangsu ProvincialInternational Trust Investment Corporation,

AHP-based System for the Health Assessment of Ancient and Famous Trees in Dongguan

By establishing an AHP-based assessment index system and assessment model,and applying detection technology that is convenient and harmless for ancient and famous trees,this paper is significant for investigating and assessing the health state of ancient and famous trees,and protecting the limited resources. Fourteen indexes such as growth vigor,disease and pest were selected from the perspectives of overall situation,canopy,trunk and root,and AHP(applied analytic hierarchy process) was applied to define weights of these indexes. According to the results,top 3 indexes in terms of weight are tree vigor,treetop death,internal decay and hole,while the indexes with lower weight are parasitism,root damage,ventilation and permeability. On the basis of assessment model and method as well as field investigation,health grade of ancient and famous trees(A) can be obtained. By grading the health of ancient and famous trees into 3 levels,each level indicates a certain health state,so managers can take corresponding maintenance measures to develop the best ecological and social value of these trees.