The electrostatic discharge(ESD)protection circuit widely exists in the input and output ports of CMOS digital circuits,and fast rising time electromagnetic pulse(FREMP)coupled into the device not only interacts with ...The electrostatic discharge(ESD)protection circuit widely exists in the input and output ports of CMOS digital circuits,and fast rising time electromagnetic pulse(FREMP)coupled into the device not only interacts with the CMOS circuit,but also acts on the protection circuit.This paper establishes a model of on-chip CMOS electrostatic discharge protection circuit and selects square pulse as the FREMP signals.Based on multiple physical parameter models,it depicts the distribution of the lattice temperature,current density,and electric field intensity inside the device.At the same time,this paper explores the changes of the internal devices in the circuit under the injection of fast rising time electromagnetic pulse and describes the relationship between the damage amplitude threshold and the pulse width.The results show that the ESD protection circuit has potential damage risk,and the injection of FREMP leads to irreversible heat loss inside the circuit.In addition,pulse signals with different attributes will change the damage threshold of the circuit.These results provide an important reference for further evaluation of the influence of electromagnetic environment on the chip,which is helpful to carry out the reliability enhancement research of ESD protection circuit.展开更多
目的探讨凝视-面-臂-言语-时间(gaze-face-arm-speech-time,G-FAST)评分对院前急救卒中前循环大血管闭塞(large vessel occlusion in the anterior circulation,aLVO)的诊断价值。方法选取2019年7月至2020年12月北京急救中心直属5个分...目的探讨凝视-面-臂-言语-时间(gaze-face-arm-speech-time,G-FAST)评分对院前急救卒中前循环大血管闭塞(large vessel occlusion in the anterior circulation,aLVO)的诊断价值。方法选取2019年7月至2020年12月北京急救中心直属5个分中心送至宣武医院,且有完整院前G-FAST评分和入院诊断信息的卒中患者,根据缺血性卒中患者是否发生LVO分为LVO和非LVO组,采用ROC曲线分析G-FAST评分对院前卒中急救aLVO的诊断价值。结果纳入患者352例,其中急性缺血性卒中占比69.0%(243/352)。进行大血管评估的急性缺血性卒中患者149例,占急性缺血性卒中的61.3%(149/243);发生aLVO患者61例,占大血管病变评估的40.9%(61/149)、占急性缺血性卒中的25.1%(61/243)。149例大血管评估的急性缺血性卒中患者中,男100例,女49例;年龄18~93岁,平均70.5岁。与非aLVO组相比,aLVO组女性较多,G-FAST评分较高,差异均有统计学意义(P<0.05)。G-FAST≥3分患者的aLVO发生率显著高于G-FAST≤2分者(68.9%比31.1%),差异有统计学意义(P<0.05)。G-FAST评分诊断院前急救卒中aLVO的ROC曲线的AUC为0.675(95%CI:0.589~0.761,P=0.000),G-FAST的cut-off值为2.5分时,灵敏度为72.10%,特异度为58.00%。结论G-FAST评分在院前急救卒中可准确识别急性缺血性患者aLVO,早诊断aLVO将利于急性缺血性患者尽早送至高级别卒中中心。展开更多
This paper reports on the time and frequency standard system for the Five-hundred meter Aperture Spherical radio Telescope(FAST),including the system design,stability measurements and pulsar timing observations.The st...This paper reports on the time and frequency standard system for the Five-hundred meter Aperture Spherical radio Telescope(FAST),including the system design,stability measurements and pulsar timing observations.The stability and drift rate of the frequency standard are calculated using 1-year monitoring data.The UTC-NIM Disciplined Oscillator(NIMDO)system improves the system time accuracy and stability to the level of 5 ns.Pulsar timing observations were carried out for several months.The weighted RMS of timing residuals reaches the level of less than 3.0μs.展开更多
In the traditional random-conformational-search model,various hypotheses with a series of meta-stable intermediate states were proposed to resolve the Levinthal paradox in protein-folding time.Here we introduce a quan...In the traditional random-conformational-search model,various hypotheses with a series of meta-stable intermediate states were proposed to resolve the Levinthal paradox in protein-folding time.Here we introduce a quantum strategy to formulate protein folding as a quantum walk on a definite graph, which provides us a g’eneral framework without making hypotheses.Evaluating it by the mean of first passage time,we find that the folding time via our quantum approach is much shorter than the one obtained via.classical random walks.This idea is expected to evoke more insights for future studies.展开更多
We propose a novel hybrid phase-locked loop (PLL) architecture for overcoming the trade-off between fast locking time and low spur. To reduce the settling time and meanwhile suppress the reference spurs, we employ a...We propose a novel hybrid phase-locked loop (PLL) architecture for overcoming the trade-off between fast locking time and low spur. To reduce the settling time and meanwhile suppress the reference spurs, we employ a wide-band single-path PLL and a narrow-band dual-path PLL in a transient state and a steady state, respectively, by changing the loop bandwidth according to the gain of voltage controlled oscillator (VCO) and the resister of the loop filter. The hybrid PLL is implemented in a 0.18-μm complementary metal oxide semiconductor (CMOS) process with a total die area of 1.4×0.46 mm2. The measured results exhibit a reference spur level of lower than -73 dB with a reference frequency of 10 MHz and a settling time of 20 μs with 40 MHz frequency jump at 2 GHz. The total power consumption of the hybrid PLL is less than 27 mW with a supply voltage of 1.8 V.展开更多
Due to their unique features,such as the inherent safety,simplified fuel cycle,and continuous on-line reprocessing,molten salt reactors(MSRs)are regarded as one of the six reference reactors in the Generation IV Inter...Due to their unique features,such as the inherent safety,simplified fuel cycle,and continuous on-line reprocessing,molten salt reactors(MSRs)are regarded as one of the six reference reactors in the Generation IV International Forum(GEN-IV).Molten chloride salt fast reactors(MCFRs)are a type of MSR.Compared to molten fluoride salt reactors(MFSRs),MCFRs have a higher solubility of heavy metal atoms,a harder neutron spectrum,lower accumulation of fission products(FPs),and better breeding and transmutation performance.Thus,MCFRs have been recognized as a type of MSR with great prospects for future development.However,as the most important feature for MSRs,the effect of different reprocessing modes on MCFRs must be researched in depth.As such,this study investigated the effect of different isotopes,especially FPs,on the neutronic performance of an MCFR,such as its breeding performance.Furthermore,the characteristics of the different reprocessing modes and MCFR rates were analyzed in terms of safety,radioactivity level,neutron economy,and breeding capacity.In the end,a reprocessing method suitable for MCFRs was determined through calculation and analysis,which provides a reference for the further research of MCFRs.展开更多
Due to actuator time delay existing in an adaptive control of the active balancing system for a fast speed-varying Jeffcott rotor, if an unsynchronized control force (correction imbalance) is applied to the system, it...Due to actuator time delay existing in an adaptive control of the active balancing system for a fast speed-varying Jeffcott rotor, if an unsynchronized control force (correction imbalance) is applied to the system, it may lead to degradation in control efficiency and instability of the control system. In order to avoid these shortcomings, a simple adaptive controller was designed for a strictly positive real rotor system with actuator time delay, then a Lyapunov-Krasovskii functional was constructed after an appropriate transform of this sys-tem model, the stability conditions of this adaptive control system with actuator time delay were derived. After adding a filter function, the active balancing system for the fast speed-varying Jeffcott rotor with actuator time delay can easily be converted to a strictly positive real system, and thus it can use the above adaptive controller satisfying the stability conditions. Finally, numerical simulations show that the adaptive controller proposed works very well to perform the active balancing for the fast speed-varying Jeffcott rotor with actuator time delay.展开更多
The absorption of neutral beam power and the fast ion stored energy in EAST plasmas with neutral beam injection(NBI)is analyzed to improve the calculation of thermal energy confinement time.The neutral beam power abso...The absorption of neutral beam power and the fast ion stored energy in EAST plasmas with neutral beam injection(NBI)is analyzed to improve the calculation of thermal energy confinement time.The neutral beam power absorption and fast ion stored energy are systematically calculated using the TRANSP code,through the investigation of global parameters including plasma current,line averaged density and beam energy.Results have shown that scaling laws for the NBI absorption coefficient and fast ion energy rate are obtained through statistical analysis.A comparison of the confinement improvement factor H98y2 with these new scaling laws against those assuming fixed coefficients is given.展开更多
Time-delay effects on synchronization features of delay-coupled slow-fast van der Pol systems are investigated in the present paper. The synchronization mechanism of “slow-manifold adjustment” is firstly described o...Time-delay effects on synchronization features of delay-coupled slow-fast van der Pol systems are investigated in the present paper. The synchronization mechanism of “slow-manifold adjustment” is firstly described on the basis of geometric singular perturbation theory. Then, the impact of time delay on the structure of the slow manifold of synchronized system is obtained by using the method of stability switch, and thus, time-delay effects on synchronization features are stated. It is shown the time delay cannot qualitatively affect the synchronization mechanism, however, it can result in the drift of the optimal coupling strength.展开更多
基金National Natural Science Foundation of China(61974116)。
文摘The electrostatic discharge(ESD)protection circuit widely exists in the input and output ports of CMOS digital circuits,and fast rising time electromagnetic pulse(FREMP)coupled into the device not only interacts with the CMOS circuit,but also acts on the protection circuit.This paper establishes a model of on-chip CMOS electrostatic discharge protection circuit and selects square pulse as the FREMP signals.Based on multiple physical parameter models,it depicts the distribution of the lattice temperature,current density,and electric field intensity inside the device.At the same time,this paper explores the changes of the internal devices in the circuit under the injection of fast rising time electromagnetic pulse and describes the relationship between the damage amplitude threshold and the pulse width.The results show that the ESD protection circuit has potential damage risk,and the injection of FREMP leads to irreversible heat loss inside the circuit.In addition,pulse signals with different attributes will change the damage threshold of the circuit.These results provide an important reference for further evaluation of the influence of electromagnetic environment on the chip,which is helpful to carry out the reliability enhancement research of ESD protection circuit.
文摘目的探讨凝视-面-臂-言语-时间(gaze-face-arm-speech-time,G-FAST)评分对院前急救卒中前循环大血管闭塞(large vessel occlusion in the anterior circulation,aLVO)的诊断价值。方法选取2019年7月至2020年12月北京急救中心直属5个分中心送至宣武医院,且有完整院前G-FAST评分和入院诊断信息的卒中患者,根据缺血性卒中患者是否发生LVO分为LVO和非LVO组,采用ROC曲线分析G-FAST评分对院前卒中急救aLVO的诊断价值。结果纳入患者352例,其中急性缺血性卒中占比69.0%(243/352)。进行大血管评估的急性缺血性卒中患者149例,占急性缺血性卒中的61.3%(149/243);发生aLVO患者61例,占大血管病变评估的40.9%(61/149)、占急性缺血性卒中的25.1%(61/243)。149例大血管评估的急性缺血性卒中患者中,男100例,女49例;年龄18~93岁,平均70.5岁。与非aLVO组相比,aLVO组女性较多,G-FAST评分较高,差异均有统计学意义(P<0.05)。G-FAST≥3分患者的aLVO发生率显著高于G-FAST≤2分者(68.9%比31.1%),差异有统计学意义(P<0.05)。G-FAST评分诊断院前急救卒中aLVO的ROC曲线的AUC为0.675(95%CI:0.589~0.761,P=0.000),G-FAST的cut-off值为2.5分时,灵敏度为72.10%,特异度为58.00%。结论G-FAST评分在院前急救卒中可准确识别急性缺血性患者aLVO,早诊断aLVO将利于急性缺血性患者尽早送至高级别卒中中心。
基金supported by the Joint Research Fund in Astronomy(Grant Nos.U1931129,U1631115 and U1831117)under cooperative agreement between NSFC and Chinese Academy of Sciences(CAS)NSFC-STINT Grant 11611130023(CH2015-6360)the National Natural Science Foundation of China(NSFC,Grant No.11403054)
文摘This paper reports on the time and frequency standard system for the Five-hundred meter Aperture Spherical radio Telescope(FAST),including the system design,stability measurements and pulsar timing observations.The stability and drift rate of the frequency standard are calculated using 1-year monitoring data.The UTC-NIM Disciplined Oscillator(NIMDO)system improves the system time accuracy and stability to the level of 5 ns.Pulsar timing observations were carried out for several months.The weighted RMS of timing residuals reaches the level of less than 3.0μs.
基金Supported by National Key R&D Program of China under Grant No 2017YFA0304304partially by the Fundamental Research Funds for the Central Universities
文摘In the traditional random-conformational-search model,various hypotheses with a series of meta-stable intermediate states were proposed to resolve the Levinthal paradox in protein-folding time.Here we introduce a quantum strategy to formulate protein folding as a quantum walk on a definite graph, which provides us a g’eneral framework without making hypotheses.Evaluating it by the mean of first passage time,we find that the folding time via our quantum approach is much shorter than the one obtained via.classical random walks.This idea is expected to evoke more insights for future studies.
基金supported by the National Natural Science Foundation of China(Grant No.61307128)the National Basic Research Program of China(GrantNo.2010CB327505)+1 种基金the Specialized Research Found for the Doctoral Program of Higher Education of China(Grant No.20131101120027)the Basic Research Foundation of Beijing Institute of Technology of China(Grant No.20120542015)
文摘We propose a novel hybrid phase-locked loop (PLL) architecture for overcoming the trade-off between fast locking time and low spur. To reduce the settling time and meanwhile suppress the reference spurs, we employ a wide-band single-path PLL and a narrow-band dual-path PLL in a transient state and a steady state, respectively, by changing the loop bandwidth according to the gain of voltage controlled oscillator (VCO) and the resister of the loop filter. The hybrid PLL is implemented in a 0.18-μm complementary metal oxide semiconductor (CMOS) process with a total die area of 1.4×0.46 mm2. The measured results exhibit a reference spur level of lower than -73 dB with a reference frequency of 10 MHz and a settling time of 20 μs with 40 MHz frequency jump at 2 GHz. The total power consumption of the hybrid PLL is less than 27 mW with a supply voltage of 1.8 V.
基金supported by the Chinese TMSR Strategic Pioneer Science and Technology Project (No.XDA02010000)the Frontier Science Key Program of Chinese Academy of Sciences (No.QYZDY-SSW-JSC016)the Shanghai Sailing Program (No.20YF1457600).
文摘Due to their unique features,such as the inherent safety,simplified fuel cycle,and continuous on-line reprocessing,molten salt reactors(MSRs)are regarded as one of the six reference reactors in the Generation IV International Forum(GEN-IV).Molten chloride salt fast reactors(MCFRs)are a type of MSR.Compared to molten fluoride salt reactors(MFSRs),MCFRs have a higher solubility of heavy metal atoms,a harder neutron spectrum,lower accumulation of fission products(FPs),and better breeding and transmutation performance.Thus,MCFRs have been recognized as a type of MSR with great prospects for future development.However,as the most important feature for MSRs,the effect of different reprocessing modes on MCFRs must be researched in depth.As such,this study investigated the effect of different isotopes,especially FPs,on the neutronic performance of an MCFR,such as its breeding performance.Furthermore,the characteristics of the different reprocessing modes and MCFR rates were analyzed in terms of safety,radioactivity level,neutron economy,and breeding capacity.In the end,a reprocessing method suitable for MCFRs was determined through calculation and analysis,which provides a reference for the further research of MCFRs.
文摘Due to actuator time delay existing in an adaptive control of the active balancing system for a fast speed-varying Jeffcott rotor, if an unsynchronized control force (correction imbalance) is applied to the system, it may lead to degradation in control efficiency and instability of the control system. In order to avoid these shortcomings, a simple adaptive controller was designed for a strictly positive real rotor system with actuator time delay, then a Lyapunov-Krasovskii functional was constructed after an appropriate transform of this sys-tem model, the stability conditions of this adaptive control system with actuator time delay were derived. After adding a filter function, the active balancing system for the fast speed-varying Jeffcott rotor with actuator time delay can easily be converted to a strictly positive real system, and thus it can use the above adaptive controller satisfying the stability conditions. Finally, numerical simulations show that the adaptive controller proposed works very well to perform the active balancing for the fast speed-varying Jeffcott rotor with actuator time delay.
基金Numerical computations were performed on the ShenMa High Performance Computing Cluster in Institute of Plasma Physics,Chinese Academy of SciencesThe work is supported by National MCF Energy R&D Program of China(Nos.2018YFE0302100,2017YFE0301100)+1 种基金National Natural Science Foundation of China(Nos.11775262,11975274,11805237,11705239)the National Magnetic Confinement Fusion Science Program of China(No.2015GB102000).
文摘The absorption of neutral beam power and the fast ion stored energy in EAST plasmas with neutral beam injection(NBI)is analyzed to improve the calculation of thermal energy confinement time.The neutral beam power absorption and fast ion stored energy are systematically calculated using the TRANSP code,through the investigation of global parameters including plasma current,line averaged density and beam energy.Results have shown that scaling laws for the NBI absorption coefficient and fast ion energy rate are obtained through statistical analysis.A comparison of the confinement improvement factor H98y2 with these new scaling laws against those assuming fixed coefficients is given.
文摘Time-delay effects on synchronization features of delay-coupled slow-fast van der Pol systems are investigated in the present paper. The synchronization mechanism of “slow-manifold adjustment” is firstly described on the basis of geometric singular perturbation theory. Then, the impact of time delay on the structure of the slow manifold of synchronized system is obtained by using the method of stability switch, and thus, time-delay effects on synchronization features are stated. It is shown the time delay cannot qualitatively affect the synchronization mechanism, however, it can result in the drift of the optimal coupling strength.