Clinical Study on the Effectiveness of Xian Fang Huo Ming Yin for Treating Cutaneous Infections and Promoting Wound Healing in Patients with Perianal Abscess

Objective:To explore the effect of the Xian Fang Huo Ming Yin(XFHM)for treating cutaneous infections and promoting wound healing in patients with perianal abscesses.Methods:Sixty-one patients with perianal abscesses who were admitted to our hospital(Xinghua City People’s Hospital)from May 2022 to May 2023 were selected and randomly divided into two groups,a control group(30 cases)and a study group(31 cases).Both groups received surgical treatment.The control group received conventional treatment and warm water fumigation,sitz bath,and surgical dressing change after surgery,while the research group received XFHM based on the control group.XFHM was taken orally and replaced with warm water for fumigation and sitz bathing.Both groups received treatment for 4 weeks but discontinued sitz bathing after 2 weeks.Various clinical indicators between the two groups were compared.Results:The total clinical effective rate and wound recovery rate of the study group were higher than that of the control group.There were differences in the wound pain scores,surrounding tissue edema,and wound secretions at different time points.Both groups experienced wound pain.The scores of wound pain,surrounding tissue edema,and wound secretions of the study group were lower than those of the control group,7 and 14 days after surgery.The serum interleukin 6(IL-6),tumor necrosis factor-alpha(TNF-α)levels,and pH values of the study group were lower than those of the control group 10 days after surgery(P<0.05).Conclusion:The application of XFHM for treating cutaneous infections and promoting wound healing in patients with perianal abscesses improved the treatment outcome,alleviated clinical symptoms,and promoted healing.

Soxllb regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish

The transcription factor Sox11 plays important roles in retinal neurogenesis during vertebrate eye development.However,its function in retina regeneration remains elusive.Here we report that Sox11 b,a zebrafish Sox11 homolog,regulates the migration and fate determination of Müller glia-derived progenitors(MGPCs)in an adult zebrafish model of mechanical retinal injury.Following a stab injury,the expression of Sox11 b was induced in proliferating MGPCs in the retina.Sox11 b knockdown did not affect MGPC formation at 4 days post-injury,although the nuclear morphology and subsequent radial migration of MGPCs were alte red.At 7 days post-injury,Sox11 b knockdown res ulted in an increased proportion of MGPCs in the inner retina and a decreased propo rtion of MGPCs in the outer nuclear layer,compared with controls.Furthermore,Sox11 b knockdown led to reduced photoreceptor regeneration,while it increased the numbe rs of newborn amacrines and retinal ganglion cells.Finally,quantitative polymerase chain reaction analysis revealed that Sox11 b regulated the expression of Notch signaling components in the retina,and Notch inhibition partially recapitulated the Sox11 b knockdown phenotype,indicating that Notch signaling functions downstream of Sox11 b.Our findings imply that Sox11 b plays key roles in MGPC migration and fate determination during retina regeneration in zebrafish,which may have critical im plications for future explorations of retinal repair in mammals.

Analysis of Dynamical Behavior of One-Dimensional Real Maps: An Executable Dynamical Programming Software Approach

The dynamical behavior of real-world phenomena is implausible graphically due to the complexity of mathematical coding. The present article has mainly focused on some one-dimensional real maps’ dynamical behavior irrespective of using coding. In continuation, linear, quadratic, cubic, higher-order, exponential, logarithmic, and absolute value maps have been used to scrutinize their dynamical behavior, including the characteristics of the orbit of points. Dynamical programming software (DPS.exe) will be proposed as a new technique to ascertain the dynamical behavior of said maps. Thus, a mathematician can automatically determine one-dimensional real maps’ dynamical behavior apart from complicated programming code and analytical solutions.

Fate of Parent and Substituted Polycyclic Aromatic Hydrocarbons in SBR/MBBR Treatment Process:Experimental Value Against Model Prediction

The knowledge of the existence,distribution and fate of polycyclic aromatic hydrocarbons(PAHs)and substituted polycyclic aromatic hydrocarbons(SPAHs)in wastewater treatment plants(WWTPs)was vital for reducing their concentrations entering the aquatic environment.The concentrations of 13 SPAHs and 16 PAHs were all determined in a WWTP with styrene butadiene rubber(SBR)in partnership with the moving bed biofilm reactor(MBBR)process.SPAHs presented a higher concentration lever than PAHs in nearly all samples.The total removal efficiencies of PAHs and SPAHs ranged from 64.0%to 71.36%and 78.4%to 79.7%,respectively.The total yearly loads of PAHs(43.0 kg)and SPAHs(73.0 kg)were mainly reduced by the primary and SBR/MBBR biological treatment stages.The tertiary treatment stage had a minor contribution to target compounds removal.According to a synthesis and improvement fate model,we found that the dominant processes changed as the chemical octanol water partition coefficient(K_(ow))increased.But the seasonal variations of experimental removal efficiencies were more obvious than that of predicted data.In the primary sedimentation tank,dissolution in the aqueous phase and sorption to sludge/particulate matter were controlling processes for the removal of PAHs and SPAHs.The sorption to sludge and biodegradation were the principal removal mechanisms during the SBR/MBBR biological treatment process.The contribution of volatilization to removal was always insignificant.Furthermore,the basic physicochemical properties and operating parameters influenced the fate of PAHs and SPAHs in the WWTP.

Fate of fertilizer nitrogen and residual nitrogen in paddy soil in Northeast China

The relationship between the fate of nitrogen (N) fertilizer and the N application rate in paddy fields in Northeast China is unclear,as is the fate of residual N.To clarify these issues,paddy field and15N microplot experiments were carried out in 2017 and 2018,with N applications at five levels:0,75,105,135 and 165 kg N ha–1(N0,N75,N105,N135 and N165,respectively).15N-labeled urea was applied to the microplots in 2017,and the same amount of unlabeled urea was applied in 2018.Ammonia (NH3) volatilization,leaching,surface runoff,rice yield,the N contents and15N abundances of both plants and soil were analyzed.The results indicated a linear platform model for rice yield and the application rate of N fertilizer,and the optimal rate was 135 kg N ha–1.N uptake increased with an increasing N rate,and the recovery efficiency of applied N (REN) values of the difference subtraction method were 45.23 and 56.98%on average in 2017and 2018,respectively.The RENwas the highest at the N rate of 135 kg ha–1in 2017 and it was insignificantly affected by the N application rate in 2018,while the agronomic efficiency of applied N (AEN) and physiological efficiency of applied N (PEN) decreased significantly when excessive N was applied.N loss through NH3volatilization,leaching and surface runoff was low in the paddy fields in Northeast China.NH3volatilization accounted for 0.81 and 2.99%of the total N application in 2017 and 2018,respectively.On average,the leaching and surface runoff rates were 4.45% and less than 1.05%,respectively,but the apparent denitrification loss was approximately 42.63%.The residual N fertilizer in the soil layer (0–40 cm) was 18.37–31.81 kg N ha–1in 2017,and the residual rate was 19.28–24.50%.Residual15N from fertilizer in the soil increased significantly with increasing N fertilizer,which was mainly concentrated in the 0–10 cm soil layer,accounting for 58.45–83.54% of the total residual N,and decreased with increasing depth.While the ratio of residual N in the 0–10 cm soil layer to that in the 0–40 cm soil layer was decreased with increasing N application.Furthermore,of the residual N,approximately 5.4%was taken up on average in the following season and 50.2%was lost,but 44.4%remained in the soil.Hence,the amount of applied N fertilizer should be reduced appropriately due to the high residual N in paddy fields in Northeast China.The appropriate N fertilizer rate in the northern fields in China was determined to be 105–135 kg N ha–1in order to achieve a balance between rice yield and high N fertilizer uptake.

The Clones’Struggle for Happiness under the Doomed Fate in Never Let Me Go

Japanese British writer Kazuo Ishiguro is one of the leading writers in contemporary British literature.He has always been committed to creating works with universal significance.Responsibility and destiny are themes that run through his works.His novel Never Let Me Go tells a story of a group of clones growing up in the Hailsham,who are given the mission to donate organs at birth.So,there is no doubt that they will inevitably end their lives in the process of donating organs to human beings again and again.The tragic life of clones is determined by the motivation of human to create them.

Review of Dietary Therapy Development in Ming and Qing Dynasties

In the Ming and Qing Dynasties,with the development of politics,economy and culture,the development of health maintenance of traditional Chinese medicine entered a heyday.Food therapy is an important part of the health theory of traditional Chinese medicine.In the 5,000 years of Chinese civilization,you can see the record of food therapy everywhere.It can be said that food therapy of traditional Chinese medicine develops together with traditional Chinese medicine.As a treasure in the treasure-house of Chinese medicine,food therapy has a long history and rich practice.Based on the current research,further research on relevant theories remains to be carried out.Focusing on the historical period of Ming and Qing dynasties,this paper takes the works related to food,nutrition and therapy(including general works and monographs on diet),the health thoughts and practice characteristics of representative health practitioners as the research perspective,and sorts out the above research contents in the past 20 years,analyzes the research overview and trend.It is found that in the study of food nourishing in Ming and Qing dynasties,there are few studies on the contents of diet nourishing in the general works.This suggests that when we study the development of diet nourishing in Ming and Qing Dynasties,we should not only study the monograph of diet nourishing and the thoughts of doctors,but also pay attention to the diet nourishing thought reflected in the general works.The study of diet monographs in Ming Dynasty mainly focused on the textual research of wild plants,and the study of diet monographs in Qing Dynasty mainly focused on the application.The study on the health care thought of doctors in Ming and Qing Dynasties mainly focused on the views of food nourishing and personal health care.These studies are summarized in order to provide reference for further theoretical research and provide reference for contemporary research on food nourishing diet.

明代地方公共典礼的庙堂设计

明代地方公共典礼不同于庙堂典礼和庶民礼仪,是指在各府州县乡、都司卫所等地方的公共领域内公开举行的,由地方政府官员主导、官民共同参与的仪式活动。地方公共典礼以仪式展演的方式表达对地方公共事务的关注,于润物无声中指向地方社会秩序的建构。明代的官方礼书、典制类史籍,以及大量官箴书中关于地方公共典礼的集中记载,展现了庙堂设计视角下公共典礼的形成及其内容。具体来讲主要包含3类:一类是官署公式,包括新官到任典礼、朝廷遣使各处开读诏敕典礼、进春鞭春仪、庆典朝贺仪与进表笺仪、日月食救护仪;一类是崇教化类礼仪,包括庙学释奠、释菜与行香礼,以及乡饮酒礼、乡射礼;一类是公共祀典,主要指各级各类坛庙祭祀。这些典礼仪式举行于开放的公共空间,以地方公共事务为内容,体现了地方社会的公共权力,推进了地方公共礼仪文化的形成。对明代地方公共典礼的研究,是理解明代地方社会礼仪秩序建构的重要内容。

猪肠道病毒感染的致病机理与营养调控研究进展

腹泻是养猪业面临的世界性难题,由猪肠道病毒感染导致的仔猪腹泻更是如此。营养与动物健康关系十分密切,营养干预已是防控肠道病毒感染的重要措施。营养干预的理论基础是弄清病毒的致病机制及营养对病毒及其感染与动物康复过程的调节作用。本文在简述猪主要肠道病毒特征基础上,重点围绕免疫、细胞命运和肠道微生物等方面总结了病毒的致病机制和营养调控作用研究进展,旨在为深入认识和研究营养与猪肠道病毒的关系,开发肠道保健和抗病营养技术提供参考。

“体用排偶”与明清制义的文体特征

“制义”是明清科举考试中经义文体的正式名称,“八股文”则是对经义文体的俗称。明代官方正式文件从不称其科举文体为“八股文”,明代的经义文集一般不以“八股文”为书名,“八股文”一词不能准确、全面揭示明清经义文的文体性质和特点。《明史·选举志》指出“体用排偶”是明代制义主体部分的文体形态特点。“排偶”包括排比和骈偶,骈偶类包括两扇、四段、六股、八股、十股、十二股、十六股等。在排比类中存在着一种股数为奇数的排比形态,如三股文、五股文、七股文、九股文,可统称为“奇股文”。奇股文的存在应引起我们重视,明清制义文体的本质与特点需要重新认识。决定明、清制义“排偶”部分文体形态的,是题目的句型结构特点和语义结构特点。当然,作者的修辞理念和兴趣也对其“排偶”设置产生影响。明代成化之后,八股形态在“排偶”诸形态中占据主流地位,这既与它契合传统文章学理念有关,也与科举考试的标准化进程是相呼应的。

从“产权单位”到“纳税单位”:《同治兰溪鱼鳞图册》所载户名考释

《同治兰溪鱼鳞图册》所载户名,根据其登记的表达方式可分为人户、祀户、族户、佃户、会户、庙户、商户、官户、客户九大类别。这些户名在鱼鳞图册上皆分为“业名”与“业户”两列登载。其中业户表达的是“产权单位”,依据“谁的土地谁承粮”的逻辑,其内涵是指“名义上的承粮户”;业名是对业户的补充与说明,其内涵是指土地的实际拥有者或税粮的实际承担者,即“业主真实姓名”。在兰溪,不管是从习惯上还是从制度上,田底主(大皮)是承粮户,但实际情况是只要某户拥有地权某个层面的权利,就可能成为实际的承粮者,故在业名之下或在其旁边以批注的形式可以登载各类经营者、佃耕者等信息,以表达这些人或单位是税粮的实际承担者。

明清家具一腿三牙结构部件类型与匠意研究

通过书籍、博物馆、拍卖会等渠道收集统计了52例具有一腿三牙结构部件的明清家具,根据一腿三牙结构部件中角牙的造型,将一腿三牙结构部件分为A类型、B类型和C类型。分类的目的是为了更好地探讨构件与构件之间的关系,分析出不同类型构造规律、构造原理以及蕴含的匠意。经探究得出,一腿三牙部件在家具中的构造原理为受力解力、加固稳定以及家具顺纹而做遵循木材的物理力学性能。此外,总结了一腿三牙结构部件所蕴含的美学内涵、线脚艺术以及其中的榫卯结构。研究结果有助于深化对一腿三牙部件的认识,同时为研究明清家具中的结构部件提供新思路。

明清鸡足山兴起中的多民族共塑与交融

大理宾川鸡足山是一座跨民族、跨地域、跨宗教的圣山。鸡足山在明清时期作为圣山兴起的过程,是区域社会中各民族对鸡足山景观的共同塑造、朝山盛节共庆、生产生活物资互通的过程,同时也是鸡足山被各民族接纳认可并被构建为多民族共享的文化符号的过程。一部鸡足山圣地的兴起史,于区域社会而言就是一段多民族共塑圣山的交往交流交融史。在各民族交往交流交融的实践过程中,鸡足山逐渐成为各民族共筑共享的精神家园。

明代文化及其历史定位

明代物质文化与精神文化双峰并峙,共开繁花。正德时期是明代文化变迁的分水岭。明代文化的动态变迁分为三个时期:一是程朱理学一统与明初文化的保守期;二是王学崛起与市民文化的形成期;三是“实学”思潮兴盛与知识阶层的内在反思期。明代堪称最有活力、多样性且具解放精神的时代,文化呈现出多元纷呈的景象,进而形塑成以个性张扬、人文主义、市民文化为主要表征的“明型文化”。在近代化的历史进程中,明代文化不但是中国文化近代化的起始,有着与世界文化进程合辙的面向;而且有不同于他者文化的独特个性,在近代化进程中展现出本土化的特色。

明清时期关中地区地震灾害时空变化特征研究

通过《陕西省志·地震志》《中国地震目录》等汇编性史料提取明清时期(1368—1912年)关中地区地震发生频次、位置、震级和地震灾害影响等信息,应用指标统计、滑动平均及语义差异分析等方法,建立关中地区地震灾害时空变化图并分析特征。结果表明:①明清时期关中地区地震有显著的阶段性、年代际和季节变化特征。1474—1676年是当地地震相对活跃期,其中1500年代和1480年代地震发生频次最高,且多发于夏季。②地震震中主要分布于关中地区中东部,且随时间变化震中逐渐分散,地震频次及强度也随之减弱。③关中地区历史地震高发期处于汾渭地震带第二活动期中,且区域空间分布特征为东强西弱。受多灾叠加、社会动荡及经济发展等因素影响,“小震大灾”情景时有发生。

地理场景与空间建构——地理与麦克白的命运

莎士比亚在《麦克白》中设置许多地理场景,构建出神秘空间和权力空间,命运随着地理场景的不同而变迁,悲剧随着空间的转换而发展,剧中的地理差异反映出麦克白悲惨命运的必然性,呈现地理即命运的观点。研究《麦克白》中的地理场景与空间建构,既提供了一种解读作品的新方法和新视角,又可以更好地理解莎士比亚如何通过地理空间表达时空体验,展现人物命运。

从王府到帝宫的跃迁--明代兴王府建筑规制演变研究

王府建筑是研究中国古代官式建筑形制的重要实物载体,具有较高的历史价值。该文借助史料文献,通过历史学研究以及图像分析法,梳理明代钟祥兴王府(龙潜旧邸)遗址的历代沿革,探寻兴王府的建筑规制特征及变迁,论述兴王府与《大明会典》中所颁定的亲王府规制的差异性以及背后的原因,为明代官式建筑研究提供独具特色的范本。

身份置换下的多元书写——论明代散曲中的代笔现象

在明代,代笔散曲的题材范围较为宽泛,其中代人赠妓或代妓赠人类曲作最多,此外还有代人抒怀、悼内、劝诫、恭贺、饯行、邀柬、嘲谑等曲作。明代散曲代笔现象的产生和多元发展,究其原因,主要有以下几个方面:一是明代文士对代笔传统的承继;二是作者的个人兴趣,以及代笔的获利、抒情、交际、娱乐等功用;三是明代重情纵欲思潮影响下的士风;四是散曲较少受到名教渗透的文体特点。这一现象具有其不可忽视的文化价值与意义。

来源原则在明清契约文书整理中的遵循:价值、困境及出路

从明清契约文书整理的相关成果来看,当前研究探讨多集中于“归户性”整理方面,而来源原则作为一项重要原则在明清契约文书整理中并未受到应有的重视。来源原则的核心思想是按档案来源进行整理和分类,保持同一来源档案不可分散、不同来源档案不得混淆,遵循来源原则对保障契约文书的完整性,保持契约原有整理方法和体系都具有积极的价值。在实践中,遵循来源原则也面临着契约文书完整性和关联性在前端已被破坏,来源信息追溯困难,整理、出版中有关信息被删节等困境。为了突破困境,在明清契约文书的整理、出版中应尊重契约的原貌和原有整理方法,尽最大可能开展研究补充与契约文书完整性和关联性密切相关的信息。

宿山:明清杭州的天竺进香及其香市

天竺分称上天竺、中天竺、下天竺,既指天竺山,又指天竺寺。在明清两代,普陀因观音而成为天下佛教名山,引得全国信众前去“朝海”;而杭州天竺因观音而名闻遐迩,进而引得信众前来“宿山”。从本地日常的烧香,到越境进香;从朝山、朝海,再到宿山,诸如此类的宗教仪式及其转向,无不说明明清民间信众的宗教信仰更趋广泛,形式也更加多样。因进香而形成的“香市”,既是宗教与经济的结缘,更是一个流动的商业市场。香市既促进了区域性市场网络的形成,又扩大了人们的社会交往,进而成为杭州的一处城市人文景观。