Objective:To evaluate the intervention effects of seated Baduanjin exercise on patients undergoing maintenance hemodialysis(MHD).Methods:A total of 108 MHD patients admitted between July 2022 and July 2023 were select...Objective:To evaluate the intervention effects of seated Baduanjin exercise on patients undergoing maintenance hemodialysis(MHD).Methods:A total of 108 MHD patients admitted between July 2022 and July 2023 were selected.They were randomly assigned into two groups:the experimental group,with 55 patients,who received seated Baduanjin exercise combined with leg exercises during dialysis;and the control group,with 53 patients,who only performed leg exercises during dialysis.The psychological state,fatigue symptoms,quality of life,and sleep quality scores were compared between the two groups,and exercise endurance was recorded.Results:After the intervention,the psychological state scores in the experimental group were lower than those in the control group,the fatigue symptom scores were lower,the quality of life scores were higher,the sleep quality scores were lower,and the exercise endurance was higher(P<0.05).Conclusion:Seated Baduanjin exercise can improve the negative psychological state and fatigue symptoms of MHD patients,enhance their quality of life and sleep quality,and effectively increase their exercise endurance.展开更多
In China,moxibustion is reported to be useful and has few side effects for chronic fatigue syndrome,but its mechanisms are largely unknown.More recently,the focus has been on the wealth of information supporting stres...In China,moxibustion is reported to be useful and has few side effects for chronic fatigue syndrome,but its mechanisms are largely unknown.More recently,the focus has been on the wealth of information supporting stress as a factor in chronic fatigue syndrome,and largely concerns dysregulation in the stress-related hypothalamic-pituitary-adrenal axis.In the present study,we aimed to determine the effect of moxibustion on behavioral symptoms in chronic fatigue syndrome rats and examine possible mechanisms.Rats were subjected to a combination of chronic restraint stress and forced swimming to induce chronic fatigue syndrome.The acupoints Guanyuan（CV4） and Zusanli（ST36,bilateral） were simultaneously administered moxibustion.Untreated chronic fatigue syndrome rats and normal rats were used as controls.Results from the forced swimming test,open field test,tail suspension test,real-time PCR,enzyme-linked immunosorbent assay,and western blot assay showed that moxibustion treatment decreased m RNA expression of corticotropin-releasing hormone in the hypothalamus,and adrenocorticotropic hormone and corticosterone levels in plasma,and markedly increased progranulin m RNA and protein expression in the hippocampus.These findings suggest that moxibustion may relieve the behavioral symptoms of chronic fatigue syndrome,at least in part,by modulating the hypothalamic-pituitary-adrenal axis and upregulating hippocampal progranulin.展开更多
基金Research Project of Sichuan Nursing Vocational College(Project No.2022RZY38)。
文摘Objective:To evaluate the intervention effects of seated Baduanjin exercise on patients undergoing maintenance hemodialysis(MHD).Methods:A total of 108 MHD patients admitted between July 2022 and July 2023 were selected.They were randomly assigned into two groups:the experimental group,with 55 patients,who received seated Baduanjin exercise combined with leg exercises during dialysis;and the control group,with 53 patients,who only performed leg exercises during dialysis.The psychological state,fatigue symptoms,quality of life,and sleep quality scores were compared between the two groups,and exercise endurance was recorded.Results:After the intervention,the psychological state scores in the experimental group were lower than those in the control group,the fatigue symptom scores were lower,the quality of life scores were higher,the sleep quality scores were lower,and the exercise endurance was higher(P<0.05).Conclusion:Seated Baduanjin exercise can improve the negative psychological state and fatigue symptoms of MHD patients,enhance their quality of life and sleep quality,and effectively increase their exercise endurance.
基金funded by the National Natural Science Foundation (No.81303034 and 81303031)China Postdoctoral Science Foundation (No.KLF501004)Development Project of Shanghai Peak Disciplines-Integrated Chinese and Western Medicine
文摘In China,moxibustion is reported to be useful and has few side effects for chronic fatigue syndrome,but its mechanisms are largely unknown.More recently,the focus has been on the wealth of information supporting stress as a factor in chronic fatigue syndrome,and largely concerns dysregulation in the stress-related hypothalamic-pituitary-adrenal axis.In the present study,we aimed to determine the effect of moxibustion on behavioral symptoms in chronic fatigue syndrome rats and examine possible mechanisms.Rats were subjected to a combination of chronic restraint stress and forced swimming to induce chronic fatigue syndrome.The acupoints Guanyuan（CV4） and Zusanli（ST36,bilateral） were simultaneously administered moxibustion.Untreated chronic fatigue syndrome rats and normal rats were used as controls.Results from the forced swimming test,open field test,tail suspension test,real-time PCR,enzyme-linked immunosorbent assay,and western blot assay showed that moxibustion treatment decreased m RNA expression of corticotropin-releasing hormone in the hypothalamus,and adrenocorticotropic hormone and corticosterone levels in plasma,and markedly increased progranulin m RNA and protein expression in the hippocampus.These findings suggest that moxibustion may relieve the behavioral symptoms of chronic fatigue syndrome,at least in part,by modulating the hypothalamic-pituitary-adrenal axis and upregulating hippocampal progranulin.
