BACKGROUND Our study expand upon a large body of evidence in the field of neuropsychiatric imaging with cognitive,affective and behavioral tasks,adapted for the functional magnetic resonance imaging(MRI)(fMRI)experime...BACKGROUND Our study expand upon a large body of evidence in the field of neuropsychiatric imaging with cognitive,affective and behavioral tasks,adapted for the functional magnetic resonance imaging(MRI)(fMRI)experimental environment.There is sufficient evidence that common networks underpin activations in task-based fMRI across different mental disorders.AIM To investigate whether there exist specific neural circuits which underpin differ-ential item responses to depressive,paranoid and neutral items(DN)in patients respectively with schizophrenia(SCZ)and major depressive disorder(MDD).METHODS 60 patients were recruited with SCZ and MDD.All patients have been scanned on 3T magnetic resonance tomography platform with functional MRI paradigm,comprised of block design,including blocks with items from diagnostic paranoid(DP),depression specific(DS)and DN from general interest scale.We performed a two-sample t-test between the two groups-SCZ patients and depressive patients.Our purpose was to observe different brain networks which were activated during a specific condition of the task,respectively DS,DP,DN.RESULTS Several significant results are demonstrated in the comparison between SCZ and depressive groups while performing this task.We identified one component that is task-related and independent of condition(shared between all three conditions),composed by regions within the temporal(right superior and middle temporal gyri),frontal(left middle and inferior frontal gyri)and limbic/salience system(right anterior insula).Another com-ponent is related to both diagnostic specific conditions(DS and DP)e.g.It is shared between DEP and SCZ,and includes frontal motor/language and parietal areas.One specific component is modulated preferentially by to the DP condition,and is related mainly to prefrontal regions,whereas other two components are significantly modulated with the DS condition and include clusters within the default mode network such as posterior cingulate and precuneus,several occipital areas,including lingual and fusiform gyrus,as well as parahippocampal gyrus.Finally,component 12 appeared to be unique for the neutral condition.In addition,there have been determined circuits across components,which are either common,or distinct in the preferential processing of the sub-scales of the task.CONCLUSION This study has delivers further evidence in support of the model of trans-disciplinary cross-validation in psychiatry.展开更多
To cope with various unpredictable changes in large scale parts,the concept of reconfigurable manufacturing system (RMS) for machining these components is presented.Considering with large-size space measurement and th...To cope with various unpredictable changes in large scale parts,the concept of reconfigurable manufacturing system (RMS) for machining these components is presented.Considering with large-size space measurement and the fixed-free manufacture mode,an automatically localizing machining method for large scale part is studied in this paper,and the architecture of the RMS for machining large scale parts is proposed.According to the method and structure,the automatically localizing model is established.The theoretical analysis and simulation examples demonstrate the feasibility and validity of the proposed method,and the results indicate that the method is suitable and effective for machining large scale components in significant scientific projects.展开更多
The research of the category and extraction methods of effective ingredients of fish scale was reviewed at home and abroad. The extraction process of fish scale was studied, including collagen, hydroxyapatite, lecithi...The research of the category and extraction methods of effective ingredients of fish scale was reviewed at home and abroad. The extraction process of fish scale was studied, including collagen, hydroxyapatite, lecithin, guanine etc. The different extraction methods and the components were analyzed. The research of effective ingredients of fish scales was reviewed as theory basis to further research and comprehensive development.展开更多
Feature extraction of signals plays an important role in classification problems because of data dimension reduction property and potential improvement of a classification accuracy rate. Principal component analysis (...Feature extraction of signals plays an important role in classification problems because of data dimension reduction property and potential improvement of a classification accuracy rate. Principal component analysis (PCA), wavelets transform or Fourier transform methods are often used for feature extraction. In this paper, we propose a multi-scale PCA, which combines discrete wavelet transform, and PCA for feature extraction of signals in both the spatial and temporal domains. Our study shows that the multi-scale PCA combined with the proposed new classification methods leads to high classification accuracy for the considered signals.展开更多
In this paper, we conduct research on the large-scale network intrusion mode based on the principal component analysis and dropquality sampling. With the growing of network security issues, invasion detection becomes ...In this paper, we conduct research on the large-scale network intrusion mode based on the principal component analysis and dropquality sampling. With the growing of network security issues, invasion detection becomes the study hotspot. There are two main types of thatinvasion detection technology, the fi rst is that misuse detection and the anomaly detection. Misuse detection can more accurately detect attacks,but high non-response rates, anomaly detection could detect the unknown attacks, but higher rate of false positives. Network invasion detectionproblem is summed up in the network data fl ow of discriminant problem, namely the judgment of network data fl ow is normal or malicious andin this sense here invasion detection problem can be understood as a pattern recognition problem. Our research integrates the PCA and samplingtechnique to propose the new idea on the IDS that is innovative and will promote the development of the corresponding techniques.展开更多
A new microelement method for the analyses of functionally graded structures was proposed. The key of this method is the maneuverable combination of two kinds of elements. Firstly, the macro elements are divided from ...A new microelement method for the analyses of functionally graded structures was proposed. The key of this method is the maneuverable combination of two kinds of elements. Firstly, the macro elements are divided from the functionally graded material structures by the normal finite elements. In order to reflect the functionally graded distributions of materials and the microconstitutions in each macro-element, the microelement method sets up the dense microelements in every macro-element, and translates nodes to the same as the normal finite elements by the degrees of freedom of all microelemental the compatibility conditions. This microelement method can fully reflect the micro constitutions and different components of materials, and its computational elements are the same as the normal finite elements, so it is an effective numerical method for the analyses of the functionally graded material structures. The three-dimensional analyses of functionally graded plates with medium components and different micro net structures are given by using the microelement method in this paper. The differences of the stress contour in the plane of functionally graded plates with different net microstructures are especially given in this paper.展开更多
目的探讨阿立哌唑和利培酮对于治疗女性精神分裂症患者的疗效。方法选取2022年7月—2023年7月福建省福州神经精神病防治院符合入组条件的85例女性精神分裂症住院患者。随机分为阿立哌唑组和利培酮组,阿立哌唑42例给予阿立哌唑治疗,利培...目的探讨阿立哌唑和利培酮对于治疗女性精神分裂症患者的疗效。方法选取2022年7月—2023年7月福建省福州神经精神病防治院符合入组条件的85例女性精神分裂症住院患者。随机分为阿立哌唑组和利培酮组,阿立哌唑42例给予阿立哌唑治疗,利培酮组43例给予利培酮治疗。比较2组在治疗前、治疗8周后阳性与阴性症状量表(positive and negative syndrome scale,PANSS)评分、P300成分、血清催乳素水平。结果治疗前,2组PANSS量表评分比较,差异无统计学意义(P>0.05);治疗后,2组PANSS量表评分比较,差异无统计学意义(P>0.05);治疗后,2组PANSS量表评分低于治疗前,差异有统计学意义(P<0.05)。治疗后,2组P300波幅均高于治疗前,差异有统计学意义(P<0.05);2组P300潜伏期与治疗前比较,差异无统计学意义(P>0.05)。治疗前,2组血清催乳素水平比较,差异无统计学意义(P>0.05);治疗后,利培酮组的血清催乳素水平为(37.785±6.068)ng/mL,高于阿立哌唑组的(28.433±5.288)ng/mL与治疗前的(25.522±5.200)ng/mL,差异有统计学意义(P<0.05)。结论阿立哌唑和利培酮作为疗效较好的临床抗精神病药物,能够有效且快速地控制临床精神症状(阴性症状和阳性症状),改善认知功能;阿立哌唑基本不引起血清催乳素水平升高,更适合推荐女性患者服用。展开更多
文摘BACKGROUND Our study expand upon a large body of evidence in the field of neuropsychiatric imaging with cognitive,affective and behavioral tasks,adapted for the functional magnetic resonance imaging(MRI)(fMRI)experimental environment.There is sufficient evidence that common networks underpin activations in task-based fMRI across different mental disorders.AIM To investigate whether there exist specific neural circuits which underpin differ-ential item responses to depressive,paranoid and neutral items(DN)in patients respectively with schizophrenia(SCZ)and major depressive disorder(MDD).METHODS 60 patients were recruited with SCZ and MDD.All patients have been scanned on 3T magnetic resonance tomography platform with functional MRI paradigm,comprised of block design,including blocks with items from diagnostic paranoid(DP),depression specific(DS)and DN from general interest scale.We performed a two-sample t-test between the two groups-SCZ patients and depressive patients.Our purpose was to observe different brain networks which were activated during a specific condition of the task,respectively DS,DP,DN.RESULTS Several significant results are demonstrated in the comparison between SCZ and depressive groups while performing this task.We identified one component that is task-related and independent of condition(shared between all three conditions),composed by regions within the temporal(right superior and middle temporal gyri),frontal(left middle and inferior frontal gyri)and limbic/salience system(right anterior insula).Another com-ponent is related to both diagnostic specific conditions(DS and DP)e.g.It is shared between DEP and SCZ,and includes frontal motor/language and parietal areas.One specific component is modulated preferentially by to the DP condition,and is related mainly to prefrontal regions,whereas other two components are significantly modulated with the DS condition and include clusters within the default mode network such as posterior cingulate and precuneus,several occipital areas,including lingual and fusiform gyrus,as well as parahippocampal gyrus.Finally,component 12 appeared to be unique for the neutral condition.In addition,there have been determined circuits across components,which are either common,or distinct in the preferential processing of the sub-scales of the task.CONCLUSION This study has delivers further evidence in support of the model of trans-disciplinary cross-validation in psychiatry.
基金Funded by the National Natural Science Foundation of Chinathe Development Program for Outstanding Young Teachers in Harbin Institute of Technology
文摘To cope with various unpredictable changes in large scale parts,the concept of reconfigurable manufacturing system (RMS) for machining these components is presented.Considering with large-size space measurement and the fixed-free manufacture mode,an automatically localizing machining method for large scale part is studied in this paper,and the architecture of the RMS for machining large scale parts is proposed.According to the method and structure,the automatically localizing model is established.The theoretical analysis and simulation examples demonstrate the feasibility and validity of the proposed method,and the results indicate that the method is suitable and effective for machining large scale components in significant scientific projects.
文摘The research of the category and extraction methods of effective ingredients of fish scale was reviewed at home and abroad. The extraction process of fish scale was studied, including collagen, hydroxyapatite, lecithin, guanine etc. The different extraction methods and the components were analyzed. The research of effective ingredients of fish scales was reviewed as theory basis to further research and comprehensive development.
文摘Feature extraction of signals plays an important role in classification problems because of data dimension reduction property and potential improvement of a classification accuracy rate. Principal component analysis (PCA), wavelets transform or Fourier transform methods are often used for feature extraction. In this paper, we propose a multi-scale PCA, which combines discrete wavelet transform, and PCA for feature extraction of signals in both the spatial and temporal domains. Our study shows that the multi-scale PCA combined with the proposed new classification methods leads to high classification accuracy for the considered signals.
文摘In this paper, we conduct research on the large-scale network intrusion mode based on the principal component analysis and dropquality sampling. With the growing of network security issues, invasion detection becomes the study hotspot. There are two main types of thatinvasion detection technology, the fi rst is that misuse detection and the anomaly detection. Misuse detection can more accurately detect attacks,but high non-response rates, anomaly detection could detect the unknown attacks, but higher rate of false positives. Network invasion detectionproblem is summed up in the network data fl ow of discriminant problem, namely the judgment of network data fl ow is normal or malicious andin this sense here invasion detection problem can be understood as a pattern recognition problem. Our research integrates the PCA and samplingtechnique to propose the new idea on the IDS that is innovative and will promote the development of the corresponding techniques.
基金supported by the National Natural Science Foundation of China (No.10432030)the National Youth Science Foundation of China (No.10802091)the Scientific and Technical Foundation of China University of Mining and Technology (No.2007B013)
文摘A new microelement method for the analyses of functionally graded structures was proposed. The key of this method is the maneuverable combination of two kinds of elements. Firstly, the macro elements are divided from the functionally graded material structures by the normal finite elements. In order to reflect the functionally graded distributions of materials and the microconstitutions in each macro-element, the microelement method sets up the dense microelements in every macro-element, and translates nodes to the same as the normal finite elements by the degrees of freedom of all microelemental the compatibility conditions. This microelement method can fully reflect the micro constitutions and different components of materials, and its computational elements are the same as the normal finite elements, so it is an effective numerical method for the analyses of the functionally graded material structures. The three-dimensional analyses of functionally graded plates with medium components and different micro net structures are given by using the microelement method in this paper. The differences of the stress contour in the plane of functionally graded plates with different net microstructures are especially given in this paper.
文摘目的探讨阿立哌唑和利培酮对于治疗女性精神分裂症患者的疗效。方法选取2022年7月—2023年7月福建省福州神经精神病防治院符合入组条件的85例女性精神分裂症住院患者。随机分为阿立哌唑组和利培酮组,阿立哌唑42例给予阿立哌唑治疗,利培酮组43例给予利培酮治疗。比较2组在治疗前、治疗8周后阳性与阴性症状量表(positive and negative syndrome scale,PANSS)评分、P300成分、血清催乳素水平。结果治疗前,2组PANSS量表评分比较,差异无统计学意义(P>0.05);治疗后,2组PANSS量表评分比较,差异无统计学意义(P>0.05);治疗后,2组PANSS量表评分低于治疗前,差异有统计学意义(P<0.05)。治疗后,2组P300波幅均高于治疗前,差异有统计学意义(P<0.05);2组P300潜伏期与治疗前比较,差异无统计学意义(P>0.05)。治疗前,2组血清催乳素水平比较,差异无统计学意义(P>0.05);治疗后,利培酮组的血清催乳素水平为(37.785±6.068)ng/mL,高于阿立哌唑组的(28.433±5.288)ng/mL与治疗前的(25.522±5.200)ng/mL,差异有统计学意义(P<0.05)。结论阿立哌唑和利培酮作为疗效较好的临床抗精神病药物,能够有效且快速地控制临床精神症状(阴性症状和阳性症状),改善认知功能;阿立哌唑基本不引起血清催乳素水平升高,更适合推荐女性患者服用。