Vibration measurements can be used to evaluate the operation status of power equipment and are widely applied in equipment quality inspection and fault identification.Event-sensing technology can sense the change in s...Vibration measurements can be used to evaluate the operation status of power equipment and are widely applied in equipment quality inspection and fault identification.Event-sensing technology can sense the change in surface light intensity caused by object vibration and provide a visual description of vibration behavior.Based on the analysis of the principle underlying the transformation of vibration behavior into event flow data by an event sensor,this paper proposes an algorithm to reconstruct event flow data into a relationship correlating vibration displacement and time to extract the amplitude-frequency characteristics of the vibration signal.A vibration measurement test platform is constructed,and feasibility and effectiveness tests are performed for the vibration motor and other power equipment.The results show that event-sensing technology can effectively perceive the surface vibration behavior of power and provide a wide dynamic range.Furthermore,the vibration measurement and visualization algorithm for power equipment constructed using this technology offers high measurement accuracy and efficiency.The results of this study provide a new noncontact and visual method for locating vibrations and performing amplitude-frequency analysis on power equipment.展开更多
BACKGROUND Intraductal papillary neoplasm of the bile duct(IPNB)is a premalignant biliarytype epithelial neoplasm with intraductal papillary or villous growth.Currently reported local palliative therapeutic modalities...BACKGROUND Intraductal papillary neoplasm of the bile duct(IPNB)is a premalignant biliarytype epithelial neoplasm with intraductal papillary or villous growth.Currently reported local palliative therapeutic modalities,including endoscopic nasobiliary drainage,stenting and biliary curettage,endoscopic biliary polypectomy,percutaneous biliary drainage,laser ablation,argon plasma coagulation,photodynamic therapy,and radiofrequency ablation to relieve mechanical obstruction are limited with weaknesses and disadvantages.We have applied percutaneous transhepatic cholangioscopy(PTCS)-assisted biliary polypectomy(PTCS-BP)technique for the management of IPNB including mucin-hypersecreting cast-like and polypoid type tumors since 2010.AIM To assess the technical feasibility,efficacy,and safety of PTCS-BP for local palliative treatment of IPNB.METHODS Patients with mucin-hypersecreting cast-like or polypoid type IPNB and receiving PTCS-BP between September 2010 and December 2019 were included.PTCS-BP was performed by using a half-moon type snare with a soft stainless-steel wire,and the tumor was snared and resected with electrocautery.The primary outcome was its feasibility,indicated by technical success.The secondary outcomes were efficacy,including therapeutic success,curative resection,and clinical success,and safety.RESULTS Five patients(four with mucin-hypersecreting cast-like type and one with polypoid type IPNB)were included.Low-and high-grade intraepithelial neoplasia(HGIN)and recurrent IPNB with invasive carcinoma were observed in one,two,and two patients,respectively.Repeated cholangitis and/or obstructive jaundice were presented in all four patients with mucin-hypersecreting cast-like type IPNB.All five patients achieved technical success of PTCS-BP.Four patients(three with mucin-hypersecreting cast-like type and one with polypoid type IPNB)obtained therapeutic success;one with mucin-hypersecreting cast-like type tumors in the intrahepatic small bile duct and HGIN had residual tumors.All four patients with mucin-hypersecreting IPNB achieved clinical success.The patient with polypoid type IPNB achieved curative resection.There were no PTCS-BP-related serious adverse events.CONCLUSION PTCS-BP appears to be feasible,efficacious,and safe for local palliative treatment of both mucin-hypersecreting cast-like and polypoid type IPNB.展开更多
Introduction: Seasonal Malaria Chemoprevention (SMC) aims at preventing malaria in children during the high transmission season. It has been recommended by the WHO since 2013 for children from the age of 3-59 months. ...Introduction: Seasonal Malaria Chemoprevention (SMC) aims at preventing malaria in children during the high transmission season. It has been recommended by the WHO since 2013 for children from the age of 3-59 months. However, despite the impact of this intervention, a peak in the prevalence and incidence of malaria is observed in children from the age of 5-9 years. The aim of this study is to determine from the current literature the feasibility, impact and cost-effectiveness of extending SMC to five cycles and to older children. Methods: A litterature search of PubMed/Medline, NCBI and Google scholar identified 1333 articles. After reading the titles and abstracts by two authors, 24 articles were selected and submitted for full reading. Random control studies on the extension of SMC, malaria, feasibility of SMC, impact of SMC and cost-effectiveness of SMC were selected. A total of 16 articles were included for the qualitative synthesis after excluding 8 studies. Results: Following the summary of the evidence, we conclude that the extension is feasible but will be confronted with the unavailability of older children. The intervention period coincides with field work. SMC is effective in reducing the prevalence and incidence of malaria and the parasite density in children. The financial cost of administering SMC is lower than that of treating a child suffering from malaria. Conclusion: After analysing the information, it was found that the majority of the African population supports the extension of the SMC to the number of cycles and the age group in order to alleviate the high mortality and morbidity rates among children due to malaria.展开更多
In this paper,the anti-tumor effects of Aconiti Radix were reviewed and summarized,and the clinical feasibility of Aconiti Radix as a potential anti-tumor drug was analyzed,in order to provide a useful reference for t...In this paper,the anti-tumor effects of Aconiti Radix were reviewed and summarized,and the clinical feasibility of Aconiti Radix as a potential anti-tumor drug was analyzed,in order to provide a useful reference for the future research and development of new anti-cancer drugs of Aconiti Radix.展开更多
Background and Aim: The incidence of incisional hernias has been reported to be around 15%. In the present scenario, a wide array of surgical procedures are available for their better management. In this study, we int...Background and Aim: The incidence of incisional hernias has been reported to be around 15%. In the present scenario, a wide array of surgical procedures are available for their better management. In this study, we intend to share our experience with one novel technique, “Hybrid IPOM (Intraperitoneal onlay meshplasty)” as a management option for a selected cohort of patients. Methods: This prospective study was undertaken during January 2019 to July 2023 at King Abdullah medical city, Makkah. A total of 51 cases were selected for Hybrid IPOM repair as per inclusion criteria;medium sized (4 - 10 cm) hernia defects;uncomplicated hernias;age more than 18 years. The follow-up period of the patients varied from 6 months to 4 years. The operation commenced with open hernia dissection, mesh deployment into abdomen, defect closure and then conversion to laparoscopy for the posterior mesh placement. Results: A total of 51 cases were repaired successfully with this technique. 48 out of 51 cases were incisional hernias secondary to some primary procedure done either for hernias itself or some other intra-abdominal pathology. The three cases were primary hernias falling in medium to large category with unaesthetic overlying skin. The age range was 19 to 72 years. The mean (range) operative time was 135 (90 - 240) min, and the average blood loss was 70 ml. The mean (range) hospital stay was 3 (2 - 11) days. All patients returned to routine work within 2 - 3 weeks of surgery. The median follow-up was 15 (6 - 48) months. Of the 51 cases, 3 patients developed seroma (managed conservatively), 1 patient developed a large hematoma (needed evacuation), and 1 patient developed superficial wound infection (managed with antibiotics). Two patients had recurrences;one patient had previously failed multiple repairs, and the other developed a postoperative hematoma. None of our patients had an iatrogenic bowel injury. Conclusion: Hybrid IPOM technique is a safe, feasible and easily reproducible technique. It may prove easier especially for beginners in laparoscopy, as it achieves faster and easy adhesiolysis thereby reducing operative time and easier establishment of the pneumoperitoneum. Besides, it gives the chance to excise ugly scars and improve the cosmesis.展开更多
The integration of 7 Tesla magnetic resonance imaging(7 T MRI)in adult patients has marked a revolutionary stride in radiology.In this article we explore the feasibility of 7 T MRI in paediatric practice,emphasizing i...The integration of 7 Tesla magnetic resonance imaging(7 T MRI)in adult patients has marked a revolutionary stride in radiology.In this article we explore the feasibility of 7 T MRI in paediatric practice,emphasizing its feasibility,applications,challenges,and safety considerations.The heightened resolution and tissue contrast of 7 T MRI offer unprecedented diagnostic accuracy,particularly in neuroimaging.Applications range from neuro-oncology to neonatal brain imaging,showcasing its efficacy in detecting subtle structural abnormalities and providing enhanced insights into neurological conditions.Despite the promise,challenges such as high cost,discomfort,and safety concerns necessitate careful consideration.Research suggests that,with precautions,7 T MRI is feasible in paediatrics,yet ongoing studies and safety assessments are imperative.展开更多
The“one-stop”student community provides new support for innovation and entrepreneurship education in universities.Integrating innovation and entrepreneurship education into the“one-stop”student community work enri...The“one-stop”student community provides new support for innovation and entrepreneurship education in universities.Integrating innovation and entrepreneurship education into the“one-stop”student community work enriches course materials,integrates teacher resources,improves students’participation in innovation and entrepreneurship,and solves problems such as low student participation,lack of course resources,insufficient teacher resources,and single evaluation methods in traditional classrooms.Through various means such as exploring course resources,innovating management models,and strengthening team construction,the role of“one-stop”student communities in innovation and entrepreneurship education has been fully utilized,promoting the development of innovation and entrepreneurship education.展开更多
The concept of the carbon cycle in the old goaf of a coal mine based on CO_(2)utilization and storage was put forward adhering to the principle of low-carbon development,utilization of space resources in old goafs,and...The concept of the carbon cycle in the old goaf of a coal mine based on CO_(2)utilization and storage was put forward adhering to the principle of low-carbon development,utilization of space resources in old goafs,and associated gas resources development.Firstly,the evolution characteristics of overburden fissures in the goaf of the case was studied using a two-dimensional physical similarity simulation test,the sealing performance of the caprocks after stabilization was analyzed,and the fissures were counted and classi-fied.Then,the process of gaseous CO_(2)injection in the connected fissure was simulated by Ansys Fluent software,and the migration law and distribution characteristics of CO_(2)under the condition of gaseous CO_(2)injection were analyzed.Finally,the estimation models of free CO_(2)storage capacity in the old goaf were constructed considering the proportion of connected fissure and the effectiveness of CO_(2)injection.The CO_(2)storage capacity in the old goaf of the case coal mine was estimated.The results showed that a caprock group of“hard-thickness low-permeability hard-thickness”was formed after the caprock-fissures system in the goaf of the case tended to be stable vertically.The connected fissure,occlude cracks,and micro-fractures in the goaf accounted for 85.5%,8.5%,and 6%of the total fissures,respectively.Gaseous CO_(2)first migrated to the bottom of the connected fissure after CO_(2)was injected into the goaf,then spread horizontally along the bottom of the connected fissure after reaching the bottom,and finally spread longitudinally after filling the bottom of the entire connected fissure.The theoretical and effective storage capacities of free CO_(2)at normal temperature and pressure in the old goaf of the case were 9757 and 7477 t,respectively.The effective storage capacity of free CO_(2)at normal temperature and pressure in the old goaf after all minefield mined was 193404 t.The research can provide some reference for the coal mining industry to help the goal of“carbon peaking and carbon neutrality”.展开更多
In this paper, we propose two hybrid inertial CQ projection algorithms with linesearch process for the split feasibility problem. Based on the hybrid CQ projection algorithm, we firstly add the inertial term into the ...In this paper, we propose two hybrid inertial CQ projection algorithms with linesearch process for the split feasibility problem. Based on the hybrid CQ projection algorithm, we firstly add the inertial term into the iteration to accelerate the convergence of the algorithm, and adopt flexible rules for selecting the stepsize and the shrinking projection region, which makes an optimal stepsize available at each iteration. The shrinking projection region is the intersection of three sets, which are the set C and two hyperplanes. Furthermore, we modify the Armijo-type line-search step in the presented algorithm to get a new algorithm.The algorithms are shown to be convergent under certain mild assumptions. Besides, numerical examples are given to show that the proposed algorithms have better performance than the general CQ algorithm.展开更多
Controlled,guided munitions can reduce dispersion in the shot,while providing the capability of engaging both stationary and maneuvering targets.The Netherlands Organisation for Applied Scientific Research has develop...Controlled,guided munitions can reduce dispersion in the shot,while providing the capability of engaging both stationary and maneuvering targets.The Netherlands Organisation for Applied Scientific Research has developed a fin-less control technology called Stagnation Pressure Reaction Control(SPRC)that takes stagnation pressure air and directs it sideways to control non-spinning projectiles.In a previous study,this technology was demonstrated at Mach 2 wind-tunnel conditions to achieve up to 1.5°controllable angle of incidence for a non-spinning,aerodynamically unstable projectile-like test object.In an operational scenario,the decelerating projectile will experience a decline in control force while the simultaneous forward shift of the center of pressure increases the need for control force.Furthermore,angles of incidence exceeding 1.5°will be experienced under realistic flight conditions,especially against maneuvering targets.This work addresses these challenges and presents an operational feasibility study for a practical application of SPRC in a non-spinning mid-caliber gun-launched projectile,using experiment data on control latency and force of the earlier study.It illustrates the combined effect of the control-and stability dynamics and underlines the potential of an SPRC projectile as a precisionoperation ammunition.This research revealed that SPRC technology can stabilize and control the hypothesized projectile in a direct fire scenario against stationary and maneuvering targets.展开更多
This paper discusses the two-block large-scale nonconvex optimization problem with general linear constraints.Based on the ideas of splitting and sequential quadratic optimization(SQO),a new feasible descent method fo...This paper discusses the two-block large-scale nonconvex optimization problem with general linear constraints.Based on the ideas of splitting and sequential quadratic optimization(SQO),a new feasible descent method for the discussed problem is proposed.First,we consider the problem of quadratic optimal(QO)approximation associated with the current feasible iteration point,and we split the QO into two small-scale QOs which can be solved in parallel.Second,a feasible descent direction for the problem is obtained and a new SQO-type method is proposed,namely,splitting feasible SQO(SF-SQO)method.Moreover,under suitable conditions,we analyse the global convergence,strong convergence and rate of superlinear convergence of the SF-SQO method.Finally,preliminary numerical experiments regarding the economic dispatch of a power system are carried out,and these show that the SF-SQO method is promising.展开更多
Fog computing brings computational services near the network edge to meet the latency constraints of cyber-physical System(CPS)applications.Edge devices enable limited computational capacity and energy availability th...Fog computing brings computational services near the network edge to meet the latency constraints of cyber-physical System(CPS)applications.Edge devices enable limited computational capacity and energy availability that hamper end user performance.We designed a novel performance measurement index to gauge a device’s resource capacity.This examination addresses the offloading mechanism issues,where the end user(EU)offloads a part of its workload to a nearby edge server(ES).Sometimes,the ES further offloads the workload to another ES or cloud server to achieve reliable performance because of limited resources(such as storage and computation).The manuscript aims to reduce the service offloading rate by selecting a potential device or server to accomplish a low average latency and service completion time to meet the deadline constraints of sub-divided services.In this regard,an adaptive online status predictive model design is significant for prognosticating the asset requirement of arrived services to make float decisions.Consequently,the development of a reinforcement learning-based flexible x-scheduling(RFXS)approach resolves the service offloading issues,where x=service/resource for producing the low latency and high performance of the network.Our approach to the theoretical bound and computational complexity is derived by formulating the system efficiency.A quadratic restraint mechanism is employed to formulate the service optimization issue according to a set ofmeasurements,as well as the behavioural association rate and adulation factor.Our system managed an average 0.89%of the service offloading rate,with 39 ms of delay over complex scenarios(using three servers with a 50%service arrival rate).The simulation outcomes confirm that the proposed scheme attained a low offloading uncertainty,and is suitable for simulating heterogeneous CPS frameworks.展开更多
With the development of satellite communication,in order to solve the problems of shortage of on-board resources and refinement of delay requirements to improve the communication performance of satellite optical netwo...With the development of satellite communication,in order to solve the problems of shortage of on-board resources and refinement of delay requirements to improve the communication performance of satellite optical networks,this paper proposes a bee colony optimization algorithm for routing and wavelength assignment based on directional guidance(DBCO-RWA)in satellite optical networks.In D-BCORWA,directional guidance based on relative position and link load is defined,and then the link cost function in the path search stage is established based on the directional guidance factor.Finally,feasible solutions are expanded in the global optimization stage.The wavelength utilization,communication success probability,blocking rate,communication hops and convergence characteristic are simulated.The results show that the performance of the proposed algorithm is improved compared with existing algorithms.展开更多
The energy industry faces a significant challenge in extracting natural gas from offshore natural gas hydrate(NGH)reservoirs,primarily due to the low productivity of wells and the high operational costs involved.The p...The energy industry faces a significant challenge in extracting natural gas from offshore natural gas hydrate(NGH)reservoirs,primarily due to the low productivity of wells and the high operational costs involved.The present study offers an assessment of the feasibility of utilizing geothermal energy to augment the production of natural gas from offshore gas hydrate reservoirs through the implementation of the methane-CO_(2)swapping technique.The present study expands the research scope of the authors beyond their previous publication,which exclusively examined the generation of methane from marine gas hydrates.Specifically,the current investigation explores the feasibility of utilizing the void spaces created by the extracted methane in the hydrate reservoir for carbon dioxide storage.Analytical models were employed to forecast the heat transfer from a geothermal zone to an NGH reservoir.A study was conducted utilizing data obtained from a reservoir situated in the Shenhu region of the Northern South China Sea.The findings of the model indicate that the implementation of geothermal heating can lead to a substantial enhancement in the productivity of wells located in heated reservoirs during CO_(2)swapping procedures.The non-linear relationship between the temperature of the heated reservoir and the rate of fold increase has been observed.It is anticipated that the fold of increase will surpass 5 when the gas hydrate reservoir undergoes a temperature rise from 6℃ to 16℃.The mathematical models utilized in this study did not incorporate the impact of heat convection resulting from CO_(2)flow into the gas reservoir.This factor has the potential to enhance well productivity.The mathematical models’deviation assumptions may cause over-prediction of well productivity in geothermal-stimulated reservoirs.Additional research is required to examine the impacts of temperature drawdown,heat convection resulting from depressurization,heat-induced gas pressure increment,and the presence of free gas in the formation containing hydrates.The process of CH4-CO_(2)swapping,which has been investigated,involves the utilization of geothermal stimulation.This method is highly encouraging as it enables the efficient injection of CO_(2)into gas hydrate reservoirs,resulting in the permanent sequestration of CO_(2)in a solid state.Additional research is warranted to examine the rate of mass transfer of CO_(2)within reservoirs of gas hydrates.展开更多
The objective of this research will be to calculate the feasibility of investing in a solar energy generation project through the development of a methodology that allows the capture of environmental uncertainties by ...The objective of this research will be to calculate the feasibility of investing in a solar energy generation project through the development of a methodology that allows the capture of environmental uncertainties by improving decision making. The article presents a comparative study of the feasibility analysis of investment in a solar mini solar energy for a Shopping, considering a regime of certainty and uncertainty. The assumed stochastic variables were energy tariff and price of solar panels. The trajectories were simulated with the binomial approach that combined resulted in a quadratic diagram. The applied methodology presented the best recommendation and the option to wait was the most valuable. The exchange of the energy obtained from LIGHT by own generation of energy with solar photovoltaic source will be viable for the manager since it observes the behavior of the variables over time and follows the rules of optimal decision.展开更多
Minimizing transportation time and getting optimal solutions are always considered as important factors while solving transportation problem. This paper shows a new approach for finding initial basic solution for tran...Minimizing transportation time and getting optimal solutions are always considered as important factors while solving transportation problem. This paper shows a new approach for finding initial basic solution for transportation problem which reduces cost of transportation more than any transportation method such as LCM, northwest, Vogel’s approximation and so on. This method has been illustrated by taking an example;afterwards, it compares basic initial feasible solution with other methods IBF and optimal dictate solutions such as MODI and Steppingstone method.展开更多
Objective:To explore the feasibility of tiotropium bromide therapy and its effect on the lung function of patients with asthma-COPD overlap syndrome(ACOS).Method:The 58 subjects selected in this study were all ACOS pa...Objective:To explore the feasibility of tiotropium bromide therapy and its effect on the lung function of patients with asthma-COPD overlap syndrome(ACOS).Method:The 58 subjects selected in this study were all ACOS patients admitted to our hospital(Hohhot First Hospital)from October 2020 to October 2022.They were grouped according to the random number table method and divided into a control group(29 cases)and an observation group(29 cases).The control group received routine treatment plus salmeterol-fluticasone powder inhalation treatment,and the observation group received tiotropium bromide treatment.The relevant indicators of the two groups were compared.Results:The total clinical effective rate of the observation group was significantly higher than that of the control group.Besides,the forced vital capacity(FVC),forced expiratory volume in 1 second(FEV1)levels,and ACT scores of the two groups increased after treatment,with the observation group having better results than the control group.The residual volume-total lung capacity ratio(RV/TLC),acute exacerbation frequency,and CAT scores all decreased,with the observation group showing smaller values than the control group.The difference between the results of both groups were significant(P<0.05)Conclusion:Tiotropium bromide has a significant clinical effect in the treatment of ACOS patients and can effectively improve the lung function of patients.展开更多
In this paper, we have used two reliable approaches (theorems) to find the optimal solutions to transportation problems, using variations in costs. In real-life scenarios, transportation costs can fluctuate due to dif...In this paper, we have used two reliable approaches (theorems) to find the optimal solutions to transportation problems, using variations in costs. In real-life scenarios, transportation costs can fluctuate due to different factors. Finding optimal solutions to the transportation problem in the context of variations in cost is vital for ensuring cost efficiency, resource allocation, customer satisfaction, competitive advantage, environmental responsibility, risk mitigation, and operational fortitude in practical situations. This paper opens up new directions for the solution of transportation problems by introducing two key theorems. By using these theorems, we can develop an algorithm for identifying the optimal solution attributes and permitting accurate quantification of changes in overall transportation costs through the addition or subtraction of constants to specific rows or columns, as well as multiplication by constants inside the cost matrix. It is anticipated that the two reliable techniques presented in this study will provide theoretical insights and practical solutions to enhance the efficiency and cost-effectiveness of transportation systems. Finally, numerical illustrations are presented to verify the proposed approaches.展开更多
With the extending scale of agricultural production,the treatment and utilization of waste have become increasingly serious environmental problem.Taking city garden and Zhongnan pasture in Pujiang Town of Minhang Dist...With the extending scale of agricultural production,the treatment and utilization of waste have become increasingly serious environmental problem.Taking city garden and Zhongnan pasture in Pujiang Town of Minhang District in Shanghai for example,according to the analysis on discharge characteristic of waste and balance of resources and energy utilization,mixed anaerobic digestion was chosen to dispose waste based on government guidance and feasibility analysis of project,and the combining disposal and resource utilization of waste were realized in two enterprises,providing reference for close cases.展开更多
基金supported by the National Key Research and Development Program of China(No.2023YFB2604600).
文摘Vibration measurements can be used to evaluate the operation status of power equipment and are widely applied in equipment quality inspection and fault identification.Event-sensing technology can sense the change in surface light intensity caused by object vibration and provide a visual description of vibration behavior.Based on the analysis of the principle underlying the transformation of vibration behavior into event flow data by an event sensor,this paper proposes an algorithm to reconstruct event flow data into a relationship correlating vibration displacement and time to extract the amplitude-frequency characteristics of the vibration signal.A vibration measurement test platform is constructed,and feasibility and effectiveness tests are performed for the vibration motor and other power equipment.The results show that event-sensing technology can effectively perceive the surface vibration behavior of power and provide a wide dynamic range.Furthermore,the vibration measurement and visualization algorithm for power equipment constructed using this technology offers high measurement accuracy and efficiency.The results of this study provide a new noncontact and visual method for locating vibrations and performing amplitude-frequency analysis on power equipment.
文摘BACKGROUND Intraductal papillary neoplasm of the bile duct(IPNB)is a premalignant biliarytype epithelial neoplasm with intraductal papillary or villous growth.Currently reported local palliative therapeutic modalities,including endoscopic nasobiliary drainage,stenting and biliary curettage,endoscopic biliary polypectomy,percutaneous biliary drainage,laser ablation,argon plasma coagulation,photodynamic therapy,and radiofrequency ablation to relieve mechanical obstruction are limited with weaknesses and disadvantages.We have applied percutaneous transhepatic cholangioscopy(PTCS)-assisted biliary polypectomy(PTCS-BP)technique for the management of IPNB including mucin-hypersecreting cast-like and polypoid type tumors since 2010.AIM To assess the technical feasibility,efficacy,and safety of PTCS-BP for local palliative treatment of IPNB.METHODS Patients with mucin-hypersecreting cast-like or polypoid type IPNB and receiving PTCS-BP between September 2010 and December 2019 were included.PTCS-BP was performed by using a half-moon type snare with a soft stainless-steel wire,and the tumor was snared and resected with electrocautery.The primary outcome was its feasibility,indicated by technical success.The secondary outcomes were efficacy,including therapeutic success,curative resection,and clinical success,and safety.RESULTS Five patients(four with mucin-hypersecreting cast-like type and one with polypoid type IPNB)were included.Low-and high-grade intraepithelial neoplasia(HGIN)and recurrent IPNB with invasive carcinoma were observed in one,two,and two patients,respectively.Repeated cholangitis and/or obstructive jaundice were presented in all four patients with mucin-hypersecreting cast-like type IPNB.All five patients achieved technical success of PTCS-BP.Four patients(three with mucin-hypersecreting cast-like type and one with polypoid type IPNB)obtained therapeutic success;one with mucin-hypersecreting cast-like type tumors in the intrahepatic small bile duct and HGIN had residual tumors.All four patients with mucin-hypersecreting IPNB achieved clinical success.The patient with polypoid type IPNB achieved curative resection.There were no PTCS-BP-related serious adverse events.CONCLUSION PTCS-BP appears to be feasible,efficacious,and safe for local palliative treatment of both mucin-hypersecreting cast-like and polypoid type IPNB.
文摘Introduction: Seasonal Malaria Chemoprevention (SMC) aims at preventing malaria in children during the high transmission season. It has been recommended by the WHO since 2013 for children from the age of 3-59 months. However, despite the impact of this intervention, a peak in the prevalence and incidence of malaria is observed in children from the age of 5-9 years. The aim of this study is to determine from the current literature the feasibility, impact and cost-effectiveness of extending SMC to five cycles and to older children. Methods: A litterature search of PubMed/Medline, NCBI and Google scholar identified 1333 articles. After reading the titles and abstracts by two authors, 24 articles were selected and submitted for full reading. Random control studies on the extension of SMC, malaria, feasibility of SMC, impact of SMC and cost-effectiveness of SMC were selected. A total of 16 articles were included for the qualitative synthesis after excluding 8 studies. Results: Following the summary of the evidence, we conclude that the extension is feasible but will be confronted with the unavailability of older children. The intervention period coincides with field work. SMC is effective in reducing the prevalence and incidence of malaria and the parasite density in children. The financial cost of administering SMC is lower than that of treating a child suffering from malaria. Conclusion: After analysing the information, it was found that the majority of the African population supports the extension of the SMC to the number of cycles and the age group in order to alleviate the high mortality and morbidity rates among children due to malaria.
基金Supported by Science and Technology Innovation Plan for Medical Workers in Shandong Province(SDYWZGKCJH2023095)Clinical Pharmacy Research Project of Shandong Provincial Medical Association(YXH2022ZX010)+1 种基金Traditional Chinese Medicine Science and Technology Development Project of Shandong Province(2019-0400&2021Q097)Traditional Chinese Medicine Research Program of Qingdao City(2020-zyy031)Medical Research Guidance Plan of Qingdao City(2020-WJZD087).
文摘In this paper,the anti-tumor effects of Aconiti Radix were reviewed and summarized,and the clinical feasibility of Aconiti Radix as a potential anti-tumor drug was analyzed,in order to provide a useful reference for the future research and development of new anti-cancer drugs of Aconiti Radix.
文摘Background and Aim: The incidence of incisional hernias has been reported to be around 15%. In the present scenario, a wide array of surgical procedures are available for their better management. In this study, we intend to share our experience with one novel technique, “Hybrid IPOM (Intraperitoneal onlay meshplasty)” as a management option for a selected cohort of patients. Methods: This prospective study was undertaken during January 2019 to July 2023 at King Abdullah medical city, Makkah. A total of 51 cases were selected for Hybrid IPOM repair as per inclusion criteria;medium sized (4 - 10 cm) hernia defects;uncomplicated hernias;age more than 18 years. The follow-up period of the patients varied from 6 months to 4 years. The operation commenced with open hernia dissection, mesh deployment into abdomen, defect closure and then conversion to laparoscopy for the posterior mesh placement. Results: A total of 51 cases were repaired successfully with this technique. 48 out of 51 cases were incisional hernias secondary to some primary procedure done either for hernias itself or some other intra-abdominal pathology. The three cases were primary hernias falling in medium to large category with unaesthetic overlying skin. The age range was 19 to 72 years. The mean (range) operative time was 135 (90 - 240) min, and the average blood loss was 70 ml. The mean (range) hospital stay was 3 (2 - 11) days. All patients returned to routine work within 2 - 3 weeks of surgery. The median follow-up was 15 (6 - 48) months. Of the 51 cases, 3 patients developed seroma (managed conservatively), 1 patient developed a large hematoma (needed evacuation), and 1 patient developed superficial wound infection (managed with antibiotics). Two patients had recurrences;one patient had previously failed multiple repairs, and the other developed a postoperative hematoma. None of our patients had an iatrogenic bowel injury. Conclusion: Hybrid IPOM technique is a safe, feasible and easily reproducible technique. It may prove easier especially for beginners in laparoscopy, as it achieves faster and easy adhesiolysis thereby reducing operative time and easier establishment of the pneumoperitoneum. Besides, it gives the chance to excise ugly scars and improve the cosmesis.
文摘The integration of 7 Tesla magnetic resonance imaging(7 T MRI)in adult patients has marked a revolutionary stride in radiology.In this article we explore the feasibility of 7 T MRI in paediatric practice,emphasizing its feasibility,applications,challenges,and safety considerations.The heightened resolution and tissue contrast of 7 T MRI offer unprecedented diagnostic accuracy,particularly in neuroimaging.Applications range from neuro-oncology to neonatal brain imaging,showcasing its efficacy in detecting subtle structural abnormalities and providing enhanced insights into neurological conditions.Despite the promise,challenges such as high cost,discomfort,and safety concerns necessitate careful consideration.Research suggests that,with precautions,7 T MRI is feasible in paediatrics,yet ongoing studies and safety assessments are imperative.
基金Jiangsu Province Philosophy and Social Sciences General Project"Exploration of the Path for Cultivating Innovation and Entrepreneurship Ability of Employment-Oriented Applied Undergraduate Talents"。
文摘The“one-stop”student community provides new support for innovation and entrepreneurship education in universities.Integrating innovation and entrepreneurship education into the“one-stop”student community work enriches course materials,integrates teacher resources,improves students’participation in innovation and entrepreneurship,and solves problems such as low student participation,lack of course resources,insufficient teacher resources,and single evaluation methods in traditional classrooms.Through various means such as exploring course resources,innovating management models,and strengthening team construction,the role of“one-stop”student communities in innovation and entrepreneurship education has been fully utilized,promoting the development of innovation and entrepreneurship education.
基金the financial support from the National Natural Science Foundation of China(No.52074217)the Natural Science Basic Research Program of Shaanxi Province(No.2021JLM-26).
文摘The concept of the carbon cycle in the old goaf of a coal mine based on CO_(2)utilization and storage was put forward adhering to the principle of low-carbon development,utilization of space resources in old goafs,and associated gas resources development.Firstly,the evolution characteristics of overburden fissures in the goaf of the case was studied using a two-dimensional physical similarity simulation test,the sealing performance of the caprocks after stabilization was analyzed,and the fissures were counted and classi-fied.Then,the process of gaseous CO_(2)injection in the connected fissure was simulated by Ansys Fluent software,and the migration law and distribution characteristics of CO_(2)under the condition of gaseous CO_(2)injection were analyzed.Finally,the estimation models of free CO_(2)storage capacity in the old goaf were constructed considering the proportion of connected fissure and the effectiveness of CO_(2)injection.The CO_(2)storage capacity in the old goaf of the case coal mine was estimated.The results showed that a caprock group of“hard-thickness low-permeability hard-thickness”was formed after the caprock-fissures system in the goaf of the case tended to be stable vertically.The connected fissure,occlude cracks,and micro-fractures in the goaf accounted for 85.5%,8.5%,and 6%of the total fissures,respectively.Gaseous CO_(2)first migrated to the bottom of the connected fissure after CO_(2)was injected into the goaf,then spread horizontally along the bottom of the connected fissure after reaching the bottom,and finally spread longitudinally after filling the bottom of the entire connected fissure.The theoretical and effective storage capacities of free CO_(2)at normal temperature and pressure in the old goaf of the case were 9757 and 7477 t,respectively.The effective storage capacity of free CO_(2)at normal temperature and pressure in the old goaf after all minefield mined was 193404 t.The research can provide some reference for the coal mining industry to help the goal of“carbon peaking and carbon neutrality”.
基金Supported by the National Natural Science Foundation of China(72071130)。
文摘In this paper, we propose two hybrid inertial CQ projection algorithms with linesearch process for the split feasibility problem. Based on the hybrid CQ projection algorithm, we firstly add the inertial term into the iteration to accelerate the convergence of the algorithm, and adopt flexible rules for selecting the stepsize and the shrinking projection region, which makes an optimal stepsize available at each iteration. The shrinking projection region is the intersection of three sets, which are the set C and two hyperplanes. Furthermore, we modify the Armijo-type line-search step in the presented algorithm to get a new algorithm.The algorithms are shown to be convergent under certain mild assumptions. Besides, numerical examples are given to show that the proposed algorithms have better performance than the general CQ algorithm.
文摘Controlled,guided munitions can reduce dispersion in the shot,while providing the capability of engaging both stationary and maneuvering targets.The Netherlands Organisation for Applied Scientific Research has developed a fin-less control technology called Stagnation Pressure Reaction Control(SPRC)that takes stagnation pressure air and directs it sideways to control non-spinning projectiles.In a previous study,this technology was demonstrated at Mach 2 wind-tunnel conditions to achieve up to 1.5°controllable angle of incidence for a non-spinning,aerodynamically unstable projectile-like test object.In an operational scenario,the decelerating projectile will experience a decline in control force while the simultaneous forward shift of the center of pressure increases the need for control force.Furthermore,angles of incidence exceeding 1.5°will be experienced under realistic flight conditions,especially against maneuvering targets.This work addresses these challenges and presents an operational feasibility study for a practical application of SPRC in a non-spinning mid-caliber gun-launched projectile,using experiment data on control latency and force of the earlier study.It illustrates the combined effect of the control-and stability dynamics and underlines the potential of an SPRC projectile as a precisionoperation ammunition.This research revealed that SPRC technology can stabilize and control the hypothesized projectile in a direct fire scenario against stationary and maneuvering targets.
基金supported by the National Natural Science Foundation of China(12171106)the Natural Science Foundation of Guangxi Province(2020GXNSFDA238017 and 2018GXNSFFA281007)the Shanghai Sailing Program(21YF1430300)。
文摘This paper discusses the two-block large-scale nonconvex optimization problem with general linear constraints.Based on the ideas of splitting and sequential quadratic optimization(SQO),a new feasible descent method for the discussed problem is proposed.First,we consider the problem of quadratic optimal(QO)approximation associated with the current feasible iteration point,and we split the QO into two small-scale QOs which can be solved in parallel.Second,a feasible descent direction for the problem is obtained and a new SQO-type method is proposed,namely,splitting feasible SQO(SF-SQO)method.Moreover,under suitable conditions,we analyse the global convergence,strong convergence and rate of superlinear convergence of the SF-SQO method.Finally,preliminary numerical experiments regarding the economic dispatch of a power system are carried out,and these show that the SF-SQO method is promising.
基金Zulqar and Kim’s research was supported in part by the Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(NRF-2021R1A6A1A03039493)in part by the NRF grant funded by the Korea government(MSIT)(NRF-2022R1A2C1004401)+1 种基金Mekala’s research was supported in part by the Basic Science Research Program of the Ministry of Education(NRF-2018R1A2B6005105)in part by the National Research Foundation of Korea(NRF)grant funded by the Korea Government(MSIT)(no.2019R1A5A8080290).
文摘Fog computing brings computational services near the network edge to meet the latency constraints of cyber-physical System(CPS)applications.Edge devices enable limited computational capacity and energy availability that hamper end user performance.We designed a novel performance measurement index to gauge a device’s resource capacity.This examination addresses the offloading mechanism issues,where the end user(EU)offloads a part of its workload to a nearby edge server(ES).Sometimes,the ES further offloads the workload to another ES or cloud server to achieve reliable performance because of limited resources(such as storage and computation).The manuscript aims to reduce the service offloading rate by selecting a potential device or server to accomplish a low average latency and service completion time to meet the deadline constraints of sub-divided services.In this regard,an adaptive online status predictive model design is significant for prognosticating the asset requirement of arrived services to make float decisions.Consequently,the development of a reinforcement learning-based flexible x-scheduling(RFXS)approach resolves the service offloading issues,where x=service/resource for producing the low latency and high performance of the network.Our approach to the theoretical bound and computational complexity is derived by formulating the system efficiency.A quadratic restraint mechanism is employed to formulate the service optimization issue according to a set ofmeasurements,as well as the behavioural association rate and adulation factor.Our system managed an average 0.89%of the service offloading rate,with 39 ms of delay over complex scenarios(using three servers with a 50%service arrival rate).The simulation outcomes confirm that the proposed scheme attained a low offloading uncertainty,and is suitable for simulating heterogeneous CPS frameworks.
基金supported in part by the National Key Research and Development Program of China under Grant 2021YFB2900604in part by the National Natural Science Foundation of China(NSFC)under Grant U22B2033,61975234,61875230。
文摘With the development of satellite communication,in order to solve the problems of shortage of on-board resources and refinement of delay requirements to improve the communication performance of satellite optical networks,this paper proposes a bee colony optimization algorithm for routing and wavelength assignment based on directional guidance(DBCO-RWA)in satellite optical networks.In D-BCORWA,directional guidance based on relative position and link load is defined,and then the link cost function in the path search stage is established based on the directional guidance factor.Finally,feasible solutions are expanded in the global optimization stage.The wavelength utilization,communication success probability,blocking rate,communication hops and convergence characteristic are simulated.The results show that the performance of the proposed algorithm is improved compared with existing algorithms.
基金funding the project“Safe,Sustainable,and Resilient Development of Offshore Reservoirs and Natural Gas Upgrading through Innovative Science and Technology:Gulf of Mexico–Mediterranean,”through Contract No.EC-19 Fossil Energy。
文摘The energy industry faces a significant challenge in extracting natural gas from offshore natural gas hydrate(NGH)reservoirs,primarily due to the low productivity of wells and the high operational costs involved.The present study offers an assessment of the feasibility of utilizing geothermal energy to augment the production of natural gas from offshore gas hydrate reservoirs through the implementation of the methane-CO_(2)swapping technique.The present study expands the research scope of the authors beyond their previous publication,which exclusively examined the generation of methane from marine gas hydrates.Specifically,the current investigation explores the feasibility of utilizing the void spaces created by the extracted methane in the hydrate reservoir for carbon dioxide storage.Analytical models were employed to forecast the heat transfer from a geothermal zone to an NGH reservoir.A study was conducted utilizing data obtained from a reservoir situated in the Shenhu region of the Northern South China Sea.The findings of the model indicate that the implementation of geothermal heating can lead to a substantial enhancement in the productivity of wells located in heated reservoirs during CO_(2)swapping procedures.The non-linear relationship between the temperature of the heated reservoir and the rate of fold increase has been observed.It is anticipated that the fold of increase will surpass 5 when the gas hydrate reservoir undergoes a temperature rise from 6℃ to 16℃.The mathematical models utilized in this study did not incorporate the impact of heat convection resulting from CO_(2)flow into the gas reservoir.This factor has the potential to enhance well productivity.The mathematical models’deviation assumptions may cause over-prediction of well productivity in geothermal-stimulated reservoirs.Additional research is required to examine the impacts of temperature drawdown,heat convection resulting from depressurization,heat-induced gas pressure increment,and the presence of free gas in the formation containing hydrates.The process of CH4-CO_(2)swapping,which has been investigated,involves the utilization of geothermal stimulation.This method is highly encouraging as it enables the efficient injection of CO_(2)into gas hydrate reservoirs,resulting in the permanent sequestration of CO_(2)in a solid state.Additional research is warranted to examine the rate of mass transfer of CO_(2)within reservoirs of gas hydrates.
文摘The objective of this research will be to calculate the feasibility of investing in a solar energy generation project through the development of a methodology that allows the capture of environmental uncertainties by improving decision making. The article presents a comparative study of the feasibility analysis of investment in a solar mini solar energy for a Shopping, considering a regime of certainty and uncertainty. The assumed stochastic variables were energy tariff and price of solar panels. The trajectories were simulated with the binomial approach that combined resulted in a quadratic diagram. The applied methodology presented the best recommendation and the option to wait was the most valuable. The exchange of the energy obtained from LIGHT by own generation of energy with solar photovoltaic source will be viable for the manager since it observes the behavior of the variables over time and follows the rules of optimal decision.
文摘Minimizing transportation time and getting optimal solutions are always considered as important factors while solving transportation problem. This paper shows a new approach for finding initial basic solution for transportation problem which reduces cost of transportation more than any transportation method such as LCM, northwest, Vogel’s approximation and so on. This method has been illustrated by taking an example;afterwards, it compares basic initial feasible solution with other methods IBF and optimal dictate solutions such as MODI and Steppingstone method.
文摘Objective:To explore the feasibility of tiotropium bromide therapy and its effect on the lung function of patients with asthma-COPD overlap syndrome(ACOS).Method:The 58 subjects selected in this study were all ACOS patients admitted to our hospital(Hohhot First Hospital)from October 2020 to October 2022.They were grouped according to the random number table method and divided into a control group(29 cases)and an observation group(29 cases).The control group received routine treatment plus salmeterol-fluticasone powder inhalation treatment,and the observation group received tiotropium bromide treatment.The relevant indicators of the two groups were compared.Results:The total clinical effective rate of the observation group was significantly higher than that of the control group.Besides,the forced vital capacity(FVC),forced expiratory volume in 1 second(FEV1)levels,and ACT scores of the two groups increased after treatment,with the observation group having better results than the control group.The residual volume-total lung capacity ratio(RV/TLC),acute exacerbation frequency,and CAT scores all decreased,with the observation group showing smaller values than the control group.The difference between the results of both groups were significant(P<0.05)Conclusion:Tiotropium bromide has a significant clinical effect in the treatment of ACOS patients and can effectively improve the lung function of patients.
文摘In this paper, we have used two reliable approaches (theorems) to find the optimal solutions to transportation problems, using variations in costs. In real-life scenarios, transportation costs can fluctuate due to different factors. Finding optimal solutions to the transportation problem in the context of variations in cost is vital for ensuring cost efficiency, resource allocation, customer satisfaction, competitive advantage, environmental responsibility, risk mitigation, and operational fortitude in practical situations. This paper opens up new directions for the solution of transportation problems by introducing two key theorems. By using these theorems, we can develop an algorithm for identifying the optimal solution attributes and permitting accurate quantification of changes in overall transportation costs through the addition or subtraction of constants to specific rows or columns, as well as multiplication by constants inside the cost matrix. It is anticipated that the two reliable techniques presented in this study will provide theoretical insights and practical solutions to enhance the efficiency and cost-effectiveness of transportation systems. Finally, numerical illustrations are presented to verify the proposed approaches.
基金Supported by Science and Technology Planning Project of Science Committee Science Committee(08DZ1980902)~~
文摘With the extending scale of agricultural production,the treatment and utilization of waste have become increasingly serious environmental problem.Taking city garden and Zhongnan pasture in Pujiang Town of Minhang District in Shanghai for example,according to the analysis on discharge characteristic of waste and balance of resources and energy utilization,mixed anaerobic digestion was chosen to dispose waste based on government guidance and feasibility analysis of project,and the combining disposal and resource utilization of waste were realized in two enterprises,providing reference for close cases.