The objective of the study was to compare the efficacy of one topical insecticide-acaricide (Frontline Tri-Act?) and of one collar (Seresto?) against fleas (Ctenocephalides felis) and ticks (Rhipicephalus sanguineus) ...The objective of the study was to compare the efficacy of one topical insecticide-acaricide (Frontline Tri-Act?) and of one collar (Seresto?) against fleas (Ctenocephalides felis) and ticks (Rhipicephalus sanguineus) on dogs exposed to bi-weekly water showering. Twenty four (24) dogs were enrolled in the study. A first set of 16 dogs were acclimatised to their cages from Day 1 to 7 and a second set of 8 dogs from Day 163 to Day 169. The 24 dogs were randomly allocated to three groups (1 to 3). Dogs assigned to Group 1 were not treated and served as negative controls. Dogs assigned to Group 2 received the Seresto? collar on Day 0 and dogs in Group 3 received Frontline Tri-Act? on Days 170 and 198. The dogs were observed hourly for four hours after treatment administration for possible adverse reactions. Dogs in Groups 1 and 2 underwent water showering on Days 14, 28, 42, 56, 70, 84, 98, 112, 126, 143 and 157. Dogs in all groups underwent water showering on Days 173, 185, 199 and 213. Dogs were infested with approximately 100 (±4) adult, unfed C. felis fleas only on Days 177, 190, 203, and 217, in alternance with infestations with 50 adult unfed R. sanguineus on Days 182, 196, 210, and 224, to assess sustained efficacy. Fleas and ticks were removed and counted on 24 and 48 hours ± 2 hours after each infestation, respectively. Frontline Tri-Act? was >99% effective against C. felis following an initial and a second monthly administration on dogs that were water showered bi-weekly. The Seresto? collar was from 68.3% to 92.9% effective against C. felis Days 178 to 218 after collar administration. Frontline Tri-Act? was effective from 87.8% to 100% against ticks whereas Seresto collar was effective from 82.2% to 94.2% from Day 184 to Day 226.展开更多
The endemic fauna of New Zealand evolved in the absence of mammalian predators and their introduction has been responsible for many extinctions and declines.Introduced species including possums(Trichosurus vulpecula K...The endemic fauna of New Zealand evolved in the absence of mammalian predators and their introduction has been responsible for many extinctions and declines.Introduced species including possums(Trichosurus vulpecula Kerr),ship rats(Rattus rattus L.)and stoats(Mustela erminea L.)are targeted to protect native birds.Control methodologies currently rely largely on labor-intensive trapping or the use of increasingly unpopular poisons,or poisons that are linked with low welfare standards.Hence,the development of safer humane predator toxins and delivery systems is highly desirable.Para-aminopropiophenone(PAPP)is being developed as a toxin for feral cats(Felis catus L.)and stoats.Carnivores appear to be much more susceptible to PAPP than birds,so it potentially has high target specificity,at least in New Zealand.Pen trials with 20 feral cats and 15 stoats have been undertaken using meat baits containing a proprietary formulation of PAPP.A PAPP dose of 20-34 mg kg^(-1)was lethal for feral cats and 37-95 mg kg^(-1)was lethal for stoats.Our assessments suggest that PAPP,for the control of feral cats and stoats,is a humane and effective toxin.PAPP causes methaemoglobinaemia,resulting in central nervous system anoxia,lethargy and death.展开更多
The aesthetic component of skin closure following surgery is important as it will likely be the only part of the surgery that the owner is likely to see.The pulley knot-free anchor used in conjunction with a continuou...The aesthetic component of skin closure following surgery is important as it will likely be the only part of the surgery that the owner is likely to see.The pulley knot-free anchor used in conjunction with a continuous intradermal pattern has been used in the in the field of human plastic surgery and has applications in veterinary surgery as well(Campbell,2004).The use of an intradermal pattern and absorbable suture material has an added benefit of not requiring suture re-展开更多
文摘The objective of the study was to compare the efficacy of one topical insecticide-acaricide (Frontline Tri-Act?) and of one collar (Seresto?) against fleas (Ctenocephalides felis) and ticks (Rhipicephalus sanguineus) on dogs exposed to bi-weekly water showering. Twenty four (24) dogs were enrolled in the study. A first set of 16 dogs were acclimatised to their cages from Day 1 to 7 and a second set of 8 dogs from Day 163 to Day 169. The 24 dogs were randomly allocated to three groups (1 to 3). Dogs assigned to Group 1 were not treated and served as negative controls. Dogs assigned to Group 2 received the Seresto? collar on Day 0 and dogs in Group 3 received Frontline Tri-Act? on Days 170 and 198. The dogs were observed hourly for four hours after treatment administration for possible adverse reactions. Dogs in Groups 1 and 2 underwent water showering on Days 14, 28, 42, 56, 70, 84, 98, 112, 126, 143 and 157. Dogs in all groups underwent water showering on Days 173, 185, 199 and 213. Dogs were infested with approximately 100 (±4) adult, unfed C. felis fleas only on Days 177, 190, 203, and 217, in alternance with infestations with 50 adult unfed R. sanguineus on Days 182, 196, 210, and 224, to assess sustained efficacy. Fleas and ticks were removed and counted on 24 and 48 hours ± 2 hours after each infestation, respectively. Frontline Tri-Act? was >99% effective against C. felis following an initial and a second monthly administration on dogs that were water showered bi-weekly. The Seresto? collar was from 68.3% to 92.9% effective against C. felis Days 178 to 218 after collar administration. Frontline Tri-Act? was effective from 87.8% to 100% against ticks whereas Seresto collar was effective from 82.2% to 94.2% from Day 184 to Day 226.
文摘The endemic fauna of New Zealand evolved in the absence of mammalian predators and their introduction has been responsible for many extinctions and declines.Introduced species including possums(Trichosurus vulpecula Kerr),ship rats(Rattus rattus L.)and stoats(Mustela erminea L.)are targeted to protect native birds.Control methodologies currently rely largely on labor-intensive trapping or the use of increasingly unpopular poisons,or poisons that are linked with low welfare standards.Hence,the development of safer humane predator toxins and delivery systems is highly desirable.Para-aminopropiophenone(PAPP)is being developed as a toxin for feral cats(Felis catus L.)and stoats.Carnivores appear to be much more susceptible to PAPP than birds,so it potentially has high target specificity,at least in New Zealand.Pen trials with 20 feral cats and 15 stoats have been undertaken using meat baits containing a proprietary formulation of PAPP.A PAPP dose of 20-34 mg kg^(-1)was lethal for feral cats and 37-95 mg kg^(-1)was lethal for stoats.Our assessments suggest that PAPP,for the control of feral cats and stoats,is a humane and effective toxin.PAPP causes methaemoglobinaemia,resulting in central nervous system anoxia,lethargy and death.
文摘The aesthetic component of skin closure following surgery is important as it will likely be the only part of the surgery that the owner is likely to see.The pulley knot-free anchor used in conjunction with a continuous intradermal pattern has been used in the in the field of human plastic surgery and has applications in veterinary surgery as well(Campbell,2004).The use of an intradermal pattern and absorbable suture material has an added benefit of not requiring suture re-