Synthesis of Glucoside Compounds of Ferrocenyl Phenols and Their Antianemic Activity

Six glucoside compounds have been synthesized by means of phase-transfer catalytic method and deacetylation from the starting material ferrocene. Their structures have been confirmed by elementary analysis, IR,1HNMR and MS. The antianemic activities of some compounds have also been tested. Results indicate that these glucoside compounds possess the antianemic activities and therefore, the further study is well worth making.

Synthesis and Characterizations of New Ferrocenyl Schiff Base with NLO Responses

A series of new stable (thermal and photochemical) ferrocenyl derivatives containing C=N bond and benzene ring in long conjugated chains have been synthesized and characterized by (HNMR)-H-1(400MHz), IR, and elemental analysis. Pull-push ferrocenyl complexes that we have prepared have strong NLO responses identified by electronic absorption spectrum.

Synthesis,Structural Characterization of Ferrocenyl Iminophosphines and Amidophosphines as Well as Their Application in the Suzuki Reaction

Ferrocenyliminophosphine 1 and 1,1′-bisferrocenyliminophosphine 2 were easily prepared from the condensation of formylferrocene or 1,1′-diformylferrocene with 2-（diphenylphosphino） aniline. The following reduction of imine group by LiAlH4 led to the formation of the corresponding ferrocenyl amidophosphines 3 and 4. The new ligands 2- 4 were well characterized by IR, ^1H NMR, ^31p NMR spectra, elemental analysis, and ESI-MS. The catalytic activity of all the ligands with palladium compounds in the Suzuki reaction was evaluated. Ligand 1, in combination with Pd （OAc）2, was found to be the most effective for the Suzuki reaction of aryl bromides with phenylboronic acid. Typically, the use of 0. 1% （molar fraction） of Pd（OAc）2/ligand 1 in the presence of two equivalents of K2CO3 as base in toluene at 110 ℃ provided good to excellent yields of the coupled products.

A New Approach to [60]Fullerene Ferrocenyl Derivative

A new approach to fullerene ferrocenyl derivative has been made. [60]Fullerene reacts with ferrocenylmethyl azide to give N-ferrocenylmethyl imino[60]fullerene in 42% yield.

Novel Zn(Ⅱ) ladder-like coordination polymer constructed from designed ferrocenyl ligand

Reaction of Zn（NO3）2·6H2O with 3-（4-carboxylphenylamino）-l-ferrocenyl-2-butylen-l-one （HL） and 4,4′-bipyfidine （4,4′- bipy） in methanol solution resulted in a novel ladder-like coordination polymer {[Zn2L2（μ2-L）2（4,4′-bipy）2]·MeOH}n （1）. Its crystal structure, thermal and electrochemical properties are presented.

Synthesis and Characterization of Novel Mercapto-end Ferrocenyl Derivatives with Schiff Base Linkage

Novel ferrocenyl derivatives of p-(10-mercaptodecyloxy) benzal 4-ferrocenylaniline have been prepared and characterized by element analysis, 1HNMR, and FAB-MS. Cyclic voltammetry has been used to characterize the self-assembled monolayers formed from the compounds on the gold electrodes.

Synthesis and Crystal Structure of (E)-[1-Ferrocenyl-2-(4-Chlorophenyl) ethylene]

The single crystal structure of the donor-acceptor ferrocenyl derivativeC18H15ClFe (Mr = 322. 62 ) has been determined, belonging to orthorhombic crystalsystem, space group P212121 with lattice parameters a= 11. 307 (2), b= 8. 471 (2 ), c=15. 427(3) A, V= 1477. 7(9) A3, Z=4, D.= 1. 45 g. cm-3, λ(MoKα) =0. 71073A,μ= 11. 9 cm-1, F(000) = 664. The final R value for 1534 observed [I>3σ(I)] reflec-tions is 0. 060. The configuration of the C =C double bond is trans. The C5H4CH =CHC6H4Cl fragrnent is almost planar. The rings of ferrocene are almost in the eclipsedpositions with each other.

Synthesis and Characterization of [60]Fullerene Ferrocenylmethyl Derivatives

Two new [60]fullerene ferrocenylmethyl derivatives have been prepared via different approaches and characterized by UV-Vis, FT-IR, NMR, FAB-MS spectra and VPO. The second approach, i.e reacting fullerene with ferrocenylmethyl azide directly, was never reported as yet.

Synthesis and Potential Application of Novel C_(2)-Symmetrical Bis(ferrocenyl)P2N Ligand

A novel chiral bis(ferrocenyl) P2N ligand 1 with C2-symmetry was synthesized through a four-step procedure from (R)-N,N-dimethyl-1-ferrocenylethylamine. In a model reaction of Pd-catalyzed allylic alkylation of 1,3-diphenylprop-2-enyl acetate 6 with dimethyl malonate, good enantioselectivity (86% e.e.) was obtained.

Electron Ionization Mass Spectrometry of Some Ferrocenyl Thia-crown Ethers

A new type of ferrocenyl thia crown ethers used as selective ligands to some poisonous metals was synthesized, and the features of their mass spectra in electron ionization mode were summarized as: (1) the strong molecular ion peaks; (2) a characteristic homologous ion series with sequential loss of C 2H 4S or C 2H 4O from M C 5H 5; (3) a new rearrangement reaction of Fe migration; (4) the uncommon loss of alcohol or thiol from the fragments of Fe rearrangement. Some typical fragmentation patterns were discussed in detail with the aid of exact mass measurement and MS/MS technique.

Synthesis and Spectroscopic Properties of Ferrocenyl Derivative Containing Donor and Acceptor Groups

Much interest has been devoted to organometallic NLO materials. We have become interested in exploring the utility of ferrocenyl group as the conjugating bridge. Thus, we synthesized 1-{{[1,3-(5-methylbenzo)dithiol]-2-yli- dene}methyl}-1’-[2-(p-nitrophenyl)-(E)-ethenyl]ferrocene (1). This new ferrocenyl compound has a donor and an acceptor group in 1,1’-positions. Investigations of the solvatochromic property of the compound revealed that it has polarized structure in a polar solvent, such as DMF. SHG efficiency of the compound was estimated by an SHEW (second-harmonic generation with the evanescent wave) method.

Synthesis and Structure of an Iridium(Ⅲ)-ferrocenyl-dithiophosphonate Complex [{Fc(OCH_3)PS_2}Ir(cod)] (Fc=Fe(η~5-C_5H_4)(η~5-C_5H_5),cod=1,5 Cyclooctadiene)

The title complex [Fc（OCH3）PS2Ir（cod）] （1, Fc = Fe（η^5-C5H4）（η^5-C5H5）, cod = 1,5-cyclooctadiene） has been prepared and characterized by X-ray diffraction analysis. It crystallizes in monoclinic, space group P21/n with a = 12.5567（5）, b = 13.5197（5）, c = 11.7833（4） A, β = 99.651（2）°, V = 1972.06（13）A^3, Z = 4, Mr = 611.52, Dc = 2.06 g/cm^3, μ（MoKα） = 7.775 mm^-, F（000） = 1184, S = 1.063, the final R = 0.0199 and wR = 0.0468 for 4063 observed reflections with I 〉 2σ（I） and 227 variables. The molecular structure of 1 shows that the central iridium atom is chelated by the [Fc（OCH3）PS2]-ligand via two sulfur atoms and coordinated by one η^4-cod molecule via four carbon atoms in a distorted octahedral coordination geometry. The average Ir-S and Ir-C bond lengths are 2.3712（8） and 2.122（3） A, respectively.

Enantioselective Reduction of Achiral Ketones with NaBH_4/I_2 Catalyzed by (S)-Ferrocenyl Amino Alcohols

The reduction reagents prepared from sodium borohydride, I-2 and a catalytic amount of chiral ferrocenyl amino alcohols 2a-e have been successfully applied to the enantioselective reduction of ketones. The optically active secondary alcohols were obtained in moderate enantiomeric excess and high chemical yield.

Synthesis and Properties of Rare Earth Complexes with 3-Ferrocenyl-5-Phenyl-Pyrazoline-1-Dithiocarbamate

Sodium 3-ferrocenyl-5-phenyl-pyrazoline-1-dithiocarbamate (FPPD) reacts with anhydrous rare earth chlorides in absolute ethanol to give 14 new complexes.The results of elemental analysis show that the compositions of the complexes are RE(FPPD)_3·nH_2O(RE=La,Pr～Lu and Y;n=3).The ligand and its complexes have been characterized by infrared spectroscopy,UV-visible absorption spectroscopy,~1H-NMR spectra,thermal analysis and molar conductivity measurement.

Novel Chiral Ferrocenyl Aziridino Alcohol Catalysts Promoting Asymmetric Addition of Diethylzinc to Aldehydes

Optically active aziridino alcohols containing ferrocenyl groups were prepared from commercially available L-threonine in excellent yields and used as catalysts to promote the asymmetric addition of diethylzinc to aryalde-hydes to afford 1-arylpropanol in up to 84% enantiomeric excesses with moderate to good yields.

Catalytic Enantioselective Reduction of Prochiral Ketones with Chiral Ferrocenyl Amino Alcohols

The asymmetric reduction of prochiral ketones was catalyzed by a class of recoverable and highly stable chiral ferrocenyl amino alcohols derived from natural amino acids to yield optically active secondary alcohols in high chemical yields and moderate to good enantiomeric excesses.

Etherification of Ferrocenyl Alcohol by Highly-efficient Ytterbium Triflate

Nucleophilic substitution of ferrocenyl alcohols with various aliphatic alcohols in the presence of a catalytic amount of ytterbium triflate [Yb（OTf）3] was studied. It was found the unsymmetrical ferrocenyl ethers could be easily obtained in excellent yields when the reactions were performed in primary and secondary alcohols. However, in other organic non-alcoholic solvents such as acetonitrile, the formation of symmetrical ferrocenyl ethers rather than unsymmetrical ones was observed.

Novel redox-active ionic thermotropic liquid crystalline complexes of polyelectrolyte and ferrocenyl surfactants

Redox-active polyelectrolyte-surfactant complexes（PSC） were prepared via the ionic self-assembly of sodium poly（styrenesulfonate） （PSS） and ferrocenyl surfactant,（11-ferrocenylundecyl）trimethylammonium bromide（FTMA） in aqueous solution. The PSS-FTMA complex exhibited an ordered interdigitated monolayer mesomorphous structure with the long period of d = 3.13 nm,and was in the ionic thermotropic liquid crystal SmA state at room temperature.Interestingly,in the solid complex, the ferrocenyl moieties formed H-aggregation showing an increase in theπ-π~＊ energy transfer of cyclopentadienes in the ferrocene moieties as known from the blue-shift in the UV spectrum.The complexes showed higher thermal stability compared with their components due to the ionic interaction.The PSS-FTMA film had a good redox reversibility,which promised to be used in electrochemical sensors.

3-二茂铁基-2-丁烯酸稀土配合物的合成及抑菌活性研究

用稀土硝酸盐与 3 二茂铁基 2 丁烯酸在 95 %乙醇中反应 ,合成了六种新的稀土配合物。由元素分析、红外光谱、电子光谱、失重分析和摩尔电导率对配合物进行了表征。并研究了配合物的抑菌活性 ,抑菌活性试验表明六种配合物具有选择性抑菌性能。

两个新的双二茂铁硫脲衍生物FcL_1和FcL_2的合成、结构及电化学性质

以二茂铁苯甲酰氯和二茂铁间(对)苯胺为原料,合成了两个新的双二茂铁硫脲衍生物FcL1和FcL2.通过IR,1HNMR和元素分析等手段确定了标题化合物的结构.X射线单晶结构分析表明,FcL1属于三斜晶系,P1空间群,R1=0.0786,wR=0.1762.电化学分析结果表明,FcL1和FcL2的电化学性质相似,说明化合物中的两个二茂铁基所处的化学环境基本相同.间苯胺取代和对苯胺取代对化合物在电极表面的扩散系数影响不大,但对其反应速率常数则有较大的影响.