OBJECTIVE: To study the clinical and pathological characteristics of solitary fibrous tumor (SFT). METHODS: Clinical pathological analysis and immunohistochemical studies were performed on ten patients with SFT. RESUL...OBJECTIVE: To study the clinical and pathological characteristics of solitary fibrous tumor (SFT). METHODS: Clinical pathological analysis and immunohistochemical studies were performed on ten patients with SFT. RESULTS: The SFTs located variously and showed different histological features. All cases showed positive staining for CD(34), VM (vimentin) and Bcl-2, but negative staining for Desmin, S-100, CK (cytokeratin) and EMA (epithelial membrane antigen). CONCLUSIONS: SFT is described as a 'patternless' growth pattern. According to clinical pathological features and immunohistochemistry, it is different from other soft tissue tumors. Long-term clinical follow-up is necessary for this kind of tumor.展开更多
文摘OBJECTIVE: To study the clinical and pathological characteristics of solitary fibrous tumor (SFT). METHODS: Clinical pathological analysis and immunohistochemical studies were performed on ten patients with SFT. RESULTS: The SFTs located variously and showed different histological features. All cases showed positive staining for CD(34), VM (vimentin) and Bcl-2, but negative staining for Desmin, S-100, CK (cytokeratin) and EMA (epithelial membrane antigen). CONCLUSIONS: SFT is described as a 'patternless' growth pattern. According to clinical pathological features and immunohistochemistry, it is different from other soft tissue tumors. Long-term clinical follow-up is necessary for this kind of tumor.
