Corneal Biomechanical Parameters and Asymmetric Visual Field Damage in Patients with Untreated Normal Tension Glaucoma

Background： High intraocular pressure （IOP） and low central corneal thickness （CCT） are important validated risk factors for glaucoma, and some studies also have suggested that eyes with more deformable corneas may be in higher risk of the development and worsening of glaucoma. In the present study, we aimed to evaluate the association between corneal biomechanical parameters and asymmetric visual field （VF） damage using a Corvis-ST device in patients with untreated normal tension glaucoma （NTG）. Methods： In this observational, cross-sectional study, 44 newly diagnosed NTG patients were enrolled. Of these, 31 had asymmetric VF damage, which was defined as a 5-point difference between the eyes according to the Advanced Glaucoma Intervention Study scoring system. Corneal biomechanical parameters were obtained using a Corvis-ST device, such as time from start until the first and second applanation is reached （time A 1 and time A2, respectively）, cord length of the first and second applanation （length A 1 and length A2, respectively）, corneal speed during the first and second applanation （velocity A1 and velocity A2, respectively）, time from start until highest concavity is reached （time HC）, maximum amplitude at the apex of highest concavity （def ampl HC）, distance between the two peaks at highest concavity （peak dist HC）, and central concave curvature at its highest concavity （radius HC）. Results： Time A 1 （7.19 q- 0.28 vs. 7.37 ~ 0.41 ms, P = 0.010）, length A 1 （1.73 [ 1.70-1.76] vs. 1.78 [ 1.76-1.79] mm, P = 0.007）, length A2 （1.58 [1.46-1.70] vs. 1.84 [h76-1.92] mm, P 〈 0.001）, peak dist HC （3.53 [3.08-4.00] vs. 4.33 [3.92-4.74] mm, P = 0.010）, and radius HC （6.20 ± 0.69 vs. 6.59 i h 18 mm, P = 0.032） were significantly lower in the worse eyes than in the better eyes, whereas velocity A 1 and def ampl HC were significantly higher （0.156 [0.149-0.163] vs. 0.145 [0.138-0.152] m/s, P= 0.002 and 1.19 ± 0.13 vs. 1.15 ± 0.13 mm, P = 0.005, respectively）. There was no significant difference in time A2, velocity A2, and time HC between the two groups. In addition, no difference was observed in lOP, CCT, and axial length. In the univariate and multivariate analyses, some of the Corvis-ST parameters, including time A1 and def ampl HC, were correlated with known risk factors for glaucoma, and there was also a significant positive correlation between def ampl HC and age. Conclusions： There were differences in dynamic corneal response parameters but not IOP or CCT between the paired eyes of NTG patients with asymmetric VF damage. We suggest that the shape of the cornea is more easily altered in the worse eyes of asymmetric NTG patients.

Analysis on characteristics of damaged field of surrounding rock and face of FMTC

Numerical simulation-FLAC^(3D) and equivalent material simulation were carried out to analyze the damaged patterns and lows, distribution of plastic width of face, and surrounding rock of FMTC during the advance of work face with different thick coal seams based on engineering geology and exploitation technology of 1151(3) fully mechanized top-coal caving (FMTC) face in Xieqiao Colliery.The results show that there is damage,and the destruction characteristics of surrounding rock and coal mass are different obviously in asymmetric exploitation layout.The damaged zone in surrounding rock and the coal of the return airway is larger than that of the intake airway.Moreover, the retained coal pillars are all damaged by tension and shear fracture, and plastic zone in coal mass in the dip direction ahead of Face is nonuniform.There are large damage zones in roof and floor strata, surrounding rock, and coal of return and intake airways near work face.The damaged zone in the upper part of Face is larger than that in middle and lower parts.The fruits of this paper are of guiding significance for engineering practices, such as support design and choice, roadway supporting and maintaining, rock pressure control of FMTC face, etc.

Characterization of deep ground geothermal field in Jiahe Coal Mine

Research into the characteristics of geothermal fields is important for the control of heat damage in mines. Based on measured geothermal data of boreholes from 200 m to 1200 m in a Jiahe Coal Mine, we demonstrate non-linear but increasing relations of both geo-temperatures and geothermal gradients with increases depth. Numerically, we fitted the relationship between geo-temperatures and depth, a first-order exponential decay curve, formulated as: T(h) = 4.975 + 23.08 exp(h/1736.1).

Risk forecasting and evaluating model of Environmental pollution accident

Environmental risk(ER) factors come from ER source and they are controlled by the primary control mechanism(PCM) of environmental risk, due to the self failures or the effects of external environment risk trigger mechanism, the PCM could not work regularly any more, then, the ER factors will release environmental space, and an ER field is formed up. The forming of ER field does not mean that any environmental pollution accident(EPA) will break out; only the ER receptors are exposed in the ER field and damaged seriously, the potential ER really turns into an actual EPA. Researching on the general laws of evolving from environmental risk to EPA, this paper bring forwards a relevant concept model of risk forecasting and evaluating of EPA. This model provides some scientific methods for risk evaluation, prevention and emergency response of EPA. This model not only enriches and develops the theory system of environment safety and emergency response, but also acts as an instruction for public safety, enterprise's safety management and emergency response of the accident.

Effect of standing-wave field distribution on femosecond laser-induced damage of HfO_2/SiO_2 mirror coating

Single-pulse and multi-pulse damage behaviors of ＂standard＂ （with A/4 stack structure） and ＂modified＂ （with reduced standing-wave field） HfO2/SiO2 mirror coatings are investigated using a commercial 50-fs, 800-nm Ti：sapphire laser system. Precise morphologies of damaged sites display strikingly different features when the samples are subjected to various number of incident pulses, which are explained reasonably by the standing-wave field distribution within the coatings. Meanwhile, the single-pulse laser-induced damage threshold of the ＂standard＂ mirror is improved by about 14% while suppressing the normalized electric field intensity at the outmost interface of the HfO2 and SiO2 layers by 37%. To discuss the damage mechanism, a theoretical model based on photoionization, avalanche ionization, and decays of electrons is adopted to simulate the evolution curves of the conduction-band electron densitv during r^ulse dHratian.

Restoration technologies of damaged paddy in hilly post-mining and subsidence-stable area of Southwest China

The paddy fields and water storage facilities are seriously damaged by the coal mine subsiding in the hilly post-mining and subsidence-stable areas in China,which make the farmers there being suffered greatly from the lack of water for traditional rice cultivation and daily life.The purpose of this paper is to find a method to restore the damaged paddy fields,thereby promoting sustainable development of land resources,and alleviating the contradiction between people and land,as well as creating a more inhabitable environment.The research methodology included field experiments,cultivated observation,and field investigation.This paper selected the Songzao Mining Area as the research area,and focused on the restoration technologies of damaged paddy fields,through the following four different measures at three experimental fields:(1)Traditional repeated cattle plowing(CK);(2)Water retention agent with repeated cattle plowing(W&C);(3)Film without holes under tilth depth(FO);and(4)Film with holes under tilth depth(FW).At last,a contrastive analysis of the four measures was made according to the results of the experiments.The results show that the use of water retaining agent with repeated cattle plowing(W&C)can be the most appropriate method to restore the damaged paddy field in the hilly post-mining and subsidence-stable area in southwest China.Compared with the other three measures,its water productivity is the maximum(0.81 kg/m3),and the net income is the highest(1403$/hm^(2)).What’s more,it is simple,short time-consuming,and low cost,which is benefit to generalize the use of this restoration technology.