Perspectives in human brain plasticity sparked by glioma invasion:from intraoperative(re)mappings to neural reconfigurations

Exploring the aptitude of the human brain to compensate functional consequences of a lesion damaging its structural architecture is a key challenge to improve patient care in various neurological diseases,to optimize neuroscientifically-informed strategies of postlesional rehabilitation,and ultimately to develop innovative neuro-regenerative therapies.The term‘plasticity’,initially referring to the intrinsic propensity of neurons to modulate their synaptic transmission in a learning situation,was progressively transposed to brain injury research and clinical neurosciences.Indeed,in the event of brain damage,adaptive mechanisms of compensation allow a partial reshaping of the structure and activities of the central nervous system,thus permitting to some extent the maintenance of brain functions.

Effects of processing parameters on figuration during the GMAW rapid prototyping process

As a deposition technology, gas metal arc welding （GMAW） has shown new promise for rapid prototyping of metallic parts. During the process of metal forming using the arc of GMA W, low heat input and stable droplet transition are critical to high quality figuration. The effects of various processing parameters on figuration quality were studied in the experiment of GMA W rapid prototyping using the wire of ERSO-6 , including welding voltage, wire feeding rate, welding speed and so on. The optimal parameters for ERSO-6 are obtained. Simultaneously, it is verified that the rapid prototyping parts with favorable structures and quality can be achieved under the conditions of low heat input and stable droplet transition.

A Heuristic for Resource Reconfiguration of Agile Manufacturing Supply Chain

The agile manufacturing is a new conception for rap id reaction to the consumers. One of its implements is establishing a virtual ente rprise (VE) around the task, where each manufacturing unit, or sub-task, probab ly have at least one resource, or referred to as suppliers. Because each manufac turing unit might be carried out in different geographical places that implies t his probably gives rise to transportation cost, the selection of resources for e ach manufacturing unit must considers not only the manufacturing price of each r esource but also the transfer cost between any two potential resources. This pap er discusses the resource reconfiguration problem with two hypotheses: 1. Permit s one or more resources to attend the same manufacturing unit as long as the tot al cost can reach its least; 2. The freight contains the initial part, that is t he freight concave. Indeed, these hypotheses are much meaningful in the real wor ld. Furthermore, to simplify the solution for this problem, we propose two conce pts: assembly tree (AT) and combinatorial mode base (CMB). Formally an AT is a c omplete production line, which can ensure the parts equilibrium, and its capacit y is subjected to the least capacity of every resources and every path in it. In the end, we propose an implicit enumeration algorithm (IEA) by the use of CMB, including it is a heuristic algorithm for integer programming (HAIP) by the use of AT. The IEA can be outlined that for a determined combinatorial mode, if it h as not enumerated, we use the HAIP to get an near optima and corresponding CMB, marking every combinatorial mode extended from the CMB as enumerated, other cont inue a new iteration. The HAIP can be outlined that for a determined combinatori al mode, there are some determined number of AT, we select an AT with the le ast slope, and select the volume of this AT to its ultimate within its capacity, iterates this doing until the needed volume reached. In the end, we conclude th is paper and prospect the deep research based on GA thought.

Discharge electrode configuration effects on the performance of a plasma sparker

A multi-electrode array is commonly applied in a plasma sparker to generate stable acoustic pulses.In this paper, the effects of the electrode configuration on the performance of a plasma sparker have been investigated. In terms of the load electrical characteristics, the electrode radius and distance have negligible influence on the electric characteristics, whereas a larger electrode number results in a smaller voltage and a larger current but has little effect on the load energy. Regarding the acoustic characteristics, both the expansion and collapse pulses can be increased by decreasing the electrode tip radius. the influence of the electrode number and electrode gap distance on the amplitude of the expansion pulse was found to be negligible. And the amplitude of the collapse pulse decreases significantly with increasing electrode number. Increasing the electrode number decreases the energy efficiency for intense bubble interactions, thus, a small electrode tip radius and a small electrode number are preferred for the design of a plasma sparker if the total discharge energy is given.

Performance Tendency of Gain and Noise Figure at Different EDFA Configurations

A comprehensive behavioral investigation of gain and noise figure （NF） at different erbium doped fiber amplifier （EDFA） configurations is proposed. Configurations such as single pass （SP）, single pass with filter （SPF）, double pass （DP） and double pass with filter （DPF） are designed, investigated and compared. A continuous increasing of gain value is recorded by changing the configuration from SP to SPF to DP then to DPF. The NF value shows different behaviors at different configurations.

Programmable droplet manipulation enabled by charged-surface pattern reconfiguration

Programmable droplet manipulation based on external stimulation is in high demand in various modern technologies.Despite notable progress,current manipulation strategies still suffer from a common drawback such as single control means of modulating the external stimulation input,which leads to huge challenges in sophisticated and large scale-up droplet handling.Herein,a unique patternreconfiguration-driven droplet manipulation method is developed on conductive/nonconductive pattern surfaces under charge deposition.Contactless charge deposition induces the“edge barrier”phenomenon at the boundaries of conductive/nonconductive patterns,analogous to an invisible and tunable wall guiding droplet behaviors.The edge barrier effect can be flexibly tuned by the nonconductive surface pattern.Thus,with charge deposition,surfaces are endowed with protean control functionality.The design of conductive/nonconductive patterns can effectively enable multifunction droplet manipulations,including track-guided sliding,sorting,merging,and mixing.Moreover,dynamical pattern reconfiguration drives programmable fluidics with sophisticated and large scale-up droplet handling capabilities in a low-cost and simple approach.

Erratum to:Vibration analysis of a gear-rotor-bearing system with outer-ring spalling and misalignment

Because of an unfortunate mistake during the production of this article,Figure 13 was wrongly inserted.The corrected Figure 13 is shown as follows.

Erratum to:Regulation of different light conditions for efficient biomass production and protein accumulation of Spirulina platensis

In this article,the legend for Fig.3 f&g was inadvertently mislabeled.The figure below shows the wrong one.The figure should have appeared as shown below.

Notice of Retraction

Retraction:Susceptibility-weighted imaging is suitable for evaluating signal strength in different brain regions of a rabbit model of acute hemorrhagic anemia https://doi.org/10.4103/1673-5374.386492 After publication of the article entitled“Susceptibility-weighted imaging is suitable for evaluating signal strength in different brain regions of a rabbit model of acute hemorrhagic anemia”(Xia et al.,2014a),concerns were raised to the journal that figures 1-5 appeared to be identical to figures 1-5 in the paper published in Medical Science Monitor(Xia et al.,2014b;doi:10.4103/1673-5374.133153).

Cortical hem signaling center: functions, development, and potential implications for evolution and brain disorders

Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical neuroepithelium.One such signaling center is the cortical hem,which arises during embryonic development at the telencephalic dorsal midline,adjacent to the choroid plexus and hippocampal primordium(Figure 1A).While the cortical hem has also been described in reptiles and birds,most of our knowledge about the developmental roles of the cortical hem is derived from the analysis in mice.The cortical hem produces several types of secreted molecules,including wingless-related integration site(Wnt)and bone morphogenetic(Bmp)proteins.The cortical hem is particularly important for the development of the hippocampus,which is involved in learning and memory,and the neocortex,which is the most complex brain region that mediates multiple types of behavior and higher cognitive functions(Mangale et al.,2008;Dal-Valle-Anton and Borrell,2022).

Regeneration mechanisms and therapeutic strategies for neuromuscular junctions in aging and diseases

The neuromuscular junction(NMJ)is an essential synaptic structure composed of motor neurons,skeletal muscles,and glial cells that orchestrate the critical process of muscle contraction(Li et al.,2018).The typical NMJ structure is classically described as having a“pretzel-like”shape in mice(Figure 1),whereas human NMJs have a smaller,fragmented structure throughout adulthood.Degenerated NMJs exhibit smaller or fragmented endplates,partial denervation,reduced numbers of synaptic vesicles,abnormal presynaptic mitochondria,and dysfunctional perisynaptic Schwann cells(Alhindi et al.,2022).

Impact of letters to the editor and publications in 2023

A letter to the editor constitutes a short communication addressing a range of topics pertinent to the readership of a journal(Dkhar,2018).This format offers several benefits,such as timeliness,accessibility,innovation,and conciseness,thereby serving as an effective means to disseminate cuttingedge scientific ideas.Over the past five years,there has been a considerable increase in the number of letters published,representing the highest growth rate(approximately 20%)observed in the last three decades(Figure 1A).In the field of academic publishing,letters to the editor are typically more concise than typical research papers.

Lactate is a potentially harmful substitute for brain glucose fuel:consequences for metabolic restoration of neurotransmission

The metabolite lactate (L-lactate) can be generated and released by diverse brain cells,including neurons,astrocytes,and oligodendrocytes (Kann,2023;Rae et al.,2024).Lactate production usually requires the degradation of glucose (D-glucose)-and glycogen in astrocytes-to pyruvate by glycolysis and subsequent conversion of pyruvate to lactate by the enzyme lactate dehydrogenase(Figure 1A;Dienel,2019;Rae et al.,2024).

Retraction:Procaine inhibits proliferation and migration and promotes cell apoptosis in osteosarcoma cells by upregulation of microRNA-133b

Following the publication,concerns have been raised about a number of figures in this article.The western blots in this article were presented with atypical,unusually shaped and possibly anomalous protein bands in many cases.The authors were contacted and invited to comment on the concerns raised and to provide the original,unmodified figures,but did not respond.The Editors-in-Chief therefore no longer have confidence in the integrity of the data in this article and decided to retract this article.

Retraction: Knockdown of Long Noncoding RNA CAT104 Inhibits the Proliferation, Migration, and Invasion of Human Osteosarcoma Cells by Regulating MicroRNA-381

Following the publication,concerns have been raised about a number of figures in this article.The western blots in this article were presented with atypical,unusually shaped and possibly anomalous protein bands in many cases.The authors were contacted and invited to comment on the concerns raised and to provide the original,unmodified figures,but did not respond.The Editors-in-Chief therefore no longer have confidence in the integrity of the data in this article and decided to retract this article.

Retraction:MicroRNA-103 promotes proliferation and inhibits apoptosis in spinal osteosarcoma cells by targeting p57

Following the publication,concerns have been raised about a number of figures in this article.The western blots in this article were presented with atypical,unusually shaped and possibly anomalous protein bands in many cases.The authors were contacted and invited to comment on the concerns raised and to provide the original,unmodified figures,but did not respond.The Editors-in-Chief therefore no longer have confidence in the integrity of the data in this article and decided to retract this article.All authors have not responded to correspondence about this retraction.As a responsible publisher,we hold the reliability and integrity of our published content in high regard.We deeply regret any inconvenience caused by this situation to our readers and all concerned parties.

Retraction:miRNA-497 negatively regulates the growth and motility of chondrosarcoma cells by targeting Cdc25A

Following the publication,concerns have been raised about a number of figures in this article.An unexpected area of similarity was identified in terms of the cellular data,where the results from differently performed experiments were intended to have been shown,although the areas immediately surrounding this area featured comparatively different distributions of cells.The authors were contacted and invited to comment on the concerns raised and to provide the original,unmodified figures,but did not respond.The Editors-in-Chief therefore no longer have confidence in the integrity of the data in this article and decided to retract this article.

From the dust:extracellular vesicles as regulators of development and neuroregeneration

First impressions can have a lasting impact.In science,this can be especially problematic,because our lack of understanding often causes us to mislabel and thus ignore important biological processes.In this vein,extracellular vesicles(EVs)were once considered to be“cellular dust”.Similar to the previous concept of“junk DNA”to describe protein non-coding regions,EVs are far more than just cellular dust.In fact,EVs are emerging as key mediators of intracellular communication across nearly all biological systems.This includes peripheral immune responses(e.g.,arthropathies and sepsis),intra-organ communication(Seim et al.,2023),and a host of other physiological and pathological states(Figure 1A and B).

Notice of Retraction

Retraction:Regulation of extracellular signal-regulated kinase 1/2 influences hippocampal neuronal survival in a rat model of diabetic cerebral ischemia.https://doi.org/10.4103/NRR.NRR-D-24-00178.Following publication of the article entitled“Regulation of extracellular signal-regulated kinase 1/2 influences hippocampal neuronal survival in a rat model of diabetic cerebral ischemia”(Zhao et al.,2014b;doi:10.4103/1673-5374.131581),concerns were raised to Neural Regeneration Research that Figure 1B and D in the paper by Zhao et al.(2014b)were identical to Figure 1D and E in the paper published in Molecular Medicine Reports(Zhao et al.,2016).

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